Two-Thirds of All Cancers Are Caused by One Thing: Your DNA
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- Опубликовано: 28 сен 2024
- While environmental factors can play a huge role, the number one cause of cancer is mutations from regular cell replication. Does this mean cancer in humans is simply inevitable?
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Researchers Find Mutation 'Hotspots' That Are Linked to Cancer
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"Researchers say they've identified clusters of genetic mutations in proteins that can give rise to cancer, a discovery that may help them zero in on new treatments. Those mutation 'hotspots' occur among families of proteins produced by genes in the body's cells. By sifting through data from nearly 6,000 cancer patients, researchers at the University of Maryland say they found thousands of mutations that occur among those proteins."
Bad luck plays larger role than environmental, genetic factors in determining who gets cancer
hub.jhu.edu/201...
"Two-thirds of adult cancer incidence across tissues can be explained not by environmental factors or inherited genes but by bad luck, according to scientists from the Johns Hopkins Kimmel Cancer Center. The unlucky findings by Johns Hopkins scientists were discovered using a statistical model that measures the proportion of cancer incidence across many tissue types. They found that more often than not, cancer in adults is caused by random mutations that occur when stem cells divide."
DNA typos to blame for most cancer mutations
www.nature.com/...
"Each time a cell divides, it provides an opportunity for errors to crop up during DNA replication. In 2015, Vogelstein and one of his co-authors, mathematician Cristian Tomasetti of Johns Hopkins University in Baltimore, created a stir with an analysis that looked at possible explanations for why some cancers occur more often than others. They concluded that differences in the number of stem-cell divisions in an organ correlated with the frequency of cancers in that area."
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This episode of Seeker was written and hosted by Trace Dominguez.
The other one third is caused by this comment section.
I think we can all agree that all comment sections are the third.
Thought buzzfeed caused most cancer
Buzzfeed is cancer itself
Stoned Avocado cure buzzfeed = cure cancer
Skinny Jasper Imagine going to your doctor to hear him say: "you've got a buzzfeed tumor in your left buzzfeed"
buzzfeed is a simple type of cance, but don't underestimate it is very aggressive and if not caught quick enough can affect the sanity of the people who have unfortunately caught it and once that happens they are forced by the cancerous cells in their brain to wright articles about why their are over a billion genders and to make random ass quizzes that make no sense, this is all done by the cancerous cells to further spread, so please for the sake of your children education them about this cancer so they can avoid catching it one day.
Stoned Avocado LOL and feminism
This is what I have been saying to my friends since my grandma died, she lived her whole life in village, never smoked nor consumed alcohol. She was a vegetarian her entire life. Lived completely on organic diet(there was no such thing as processed food ). She was a perfectly healthy person, until she was diagnosed with pancreatic cancer when she was 78 and died within 6 months of finding it.
I read somewhere that vegetarians were the ones who get cancer more so than any other group.
Boma Boma same story with my 65yo uncle,but he died sooner,he knew that he had to die and my family were in a final destination similar plot,a lot of ppl died from the familly,he knew he was the next,he enteres depresion,gave up and died,wonder who will die next now...this happened 2weeks ago
Exactly. Worrying about getting cancer might not give you cancer, but it can make your life just as miserable. We're all gonna die, enjoy it while youve got it.
Heads will roll once the public discovers that cancer is not a natural occurrence but in fact a microbial infection...
fasting and large amounts of antioxidants negative cancer and this rap cell growth that happens when you eat foods that spike IGF1
next week in media:
DNA is CANCEROUS study says.
in comment section: ''HOW DO I GET RID OF IT? IS THERE A DIET THAT COULD PREVENT DNA IN MY BODY''
failandia even if cancer form in the body due to random mutation ( which happens every day btw) the body is able to fight and kill the cancer cells. To which degree the body is able to shut down these early cancers is heavily influenced by nutrition and lifestyle. I recommend a book called " the China study" if you want to get more info on the topic.
If you go to medical conferences, there is increasing a talk of cancer being more about diet oxidative damage preceding DNA damage. More people are revisiting the mitochondrial origin hypothesis of cancer.
If you stick the wrong cog into a clock, it either won't work or it will damage/break other parts.
That's the most basic way I can think to describe cancer.
Dr.StickFigure Thank you for the insight
Dr.StickFigure do you mean this "Warburg theory of cancer"? As per wiki, it seems it's more a manifestation of the cancerous DNA than the cause...
Sir Dr.Stickfigure, just wondering, why does oxidization damage DNA? Does that mean if more people are stressed, they higher their chances of cancer?
well they are called "free radicals" and they are comparable to radiation (fun fact: oxygen in your blood is a free radical)
If Einstein was only a cancer researcher.
wow
I feel like this is an oversimplification of cancer because it's my understanding we all have cancer it's just a matter of whether or not we enable cancer to flourish. Some foods are anti angiogenesis which prevents cancers from establishing a fuel source. Also protein restriction like methionine restriction has been shown to reverse cancer or turn it off. What about epigenetics?
This is depressing :( the majority of my father's part of my family suffered from one type of cancer :(
Video starts 0:00
Pomegranate Pro thanks ive been looking for it.
As a 90s kid, I'm confident with future science of curing cancer
Sorry to say, but it will never happen. Its sad, but the truth.
Brewer why are you so negative?
General Grievous probably because there are so many types of cancer it's hard to cure them all but i think it's possible once we have nano bots
Boils down to money, Far more money to be made in treating a disease/cancer than curing it. Sad but true.
Think of it this way, even if we could delay cells turning cancerous, its only a delay, and the more you delay the more other organs and cells will fail for other medical reasons. Eventually science could even surpass all our biological limitations. not just little old cancer.
Thanks for existing Seeker !
the background music made the video so inspiring, very nice
I have been following you guys for a year now. I really love when you guys make big episodes on interesting topics like cancer.
So please make big videos in seeker or seeker plus like the episode about infra radiation.
I love this channel. It makes me think, and then go do research for myself. Best ever!!
Of course it's our DNA!
I thought this was basic knowledge.
which is why some families seem to have more cancer, and some no cancer.
What if... I am cancer?
Michael The Sociopath boi....
Then there’s a lot of doctors with a contract on you
Don't say that :c
The main cause of cancer is that we living longer. In the past not many people live to be 80-100+ years, so cancer was not so common back then. As we get older, there is higher chance we get mutated cells, it is just probability.
Answering Machine such a logical comments
This comments make sense
gosh this makes me even more scared of cancer. No matter how healthy I can be, there is a chance of me getting it.
A very interesting video. Trey however, has a way of making things interesting. When I asked my cancer specialist why I got lymphoma he looked at me seriously and said: "Bad luck".
Thanks. This was a helpful one and honest.
Can you give us the title of the paper that you mentioned?
I feel like a couple of weeks ago I ate a strawberry that definitely had cancer. I could just taste it and it was weird.
That was a mealworm. Congrats on upping your protein intake.
Your immune system killing cancer is also normal though so still abnormal for it to develop into something detectable.
True. Notice also radiation fallout from Nuclear tests also have caused a great deal of Cancer in America.
Your defiantly my favorite speaker or host
If a group of people tell you "this is how it works" will you assimilate to their form of reasoning or will you try to make sense of it in your own way, and if those very few trust and believe in you, your efforts are not in vain. As long we "try" the definition of "you can't" is never everlasting.
The last time I came here, I still had cancer.
Just about everyone in my family over 30 has cancer, maternal and paternal. I just can’t wait until I reach that magic age. I live knowing there’s a bullet out there and it’s traveling straight towards my chest.
Great video. The most important message to take away from this is that we shouldn't miss the big picture. Try to understand cancer, in-depth. And it might take a lot more work and advances in science than we'd like to solve this problem.
We all are gonna die anyways though
Tell Me This using that logic lets just end humanity altogether right?
Even if they stopped aging and all disease related deaths.We would all inevitably die by accidents, only difference is our life expectancy might sky rocket to 1,000+ average years.
switch your DNA for the new XNA which is far less likely to attain mutations
where did he get that T-shirt from? I want one 😊
If cancer is down to genetics, can a gene or DNA test tell me if I am predestined to be affected by cancer??
Make a video about why do we get goosebumps when two metal scrub
I love how this guy smiles even when talking about cancer!
2:19 How many countries, Trace?
our entire molecular structure sheds away over our existence..and as the inner new cells they take the affects of everything you have been doing for your physical body..your metaphysical. The amount of stress and all the hormones youve had for the set amount of time in cell replication. There are many ways of keeping the body clean..that important to look at. Aloe Vera juice is very helpful and eat very spacious as in not large amounts rather small and very complexly mixed in the groupings of them. This is really the 1 true way to eat as far as any forgive the phrase.. diet is concerned. Avoiding meats more then having them is important..of course the quality of your water is one simple key factor for people to ensure they use that well..good clean water with ph around 7 or 9 is great for alkaline which is another key to eat more of..alkaline foods which is vast. eating is so much simpler then has been made to look for average people..for special diets of course special attention. enjoy eating and your health. stay away from soda pop..that stuffs horrible. any of it.
Why do your videos suddenly look much nicer?
Trace....u r d best....please make a video on effect of spicy 🌶 food on mood.....luv u guys
yes! I am a Cancer and I need to be understood and accepted! :-P
I got loyalty got royalty inside my DNA
This is actually kind of scary. It's natural and happens. We need some Philosophical questions, LOTS of careful logical thinking, and a pinch of existential crisis.
Folner Willies I was thinking the same thing.
I used to really like this channel but now I'm wondering if you guys receive funding from the pharmaceutical industry. Since this is not the first video from your channel that has downplayed the power of lifestyle changes and made it sound like the chances of developing a specific condition is completely controlled by our genes and out of our control.
As a scientist that regularly reads through the peer review literature I can tell you, you're partly right. Lifestyle changes such as diets rich in antioxidants (not supplements) play a huge role in mitigating DNA damage in addition these foods inhibit angiogenesis, are low in IGF-1s (which most cancer cells have receptors for) and prevent the cancer from metastasizing.
Furthermore you forget to mention that lifestyle changes such as diet, exercise and effective stress management can up-regulate or down-regulate specific genes in our body that play a crucial role in cancer suppression. This is independent of the specific type of cancer.
Great to see you spreading more misleading news to make those that don't know any better feel helpless and at the mercy of western medicine... I hope Discovery is spending that Pharma money well.
For any viewers that want a credible reference on cancer research...
ruclips.net/video/0VX_oZBMSd4/видео.html
Does this mean that Nad+ will also potentially prevent cancer when it isn't genetically inevitable?
I love how the purple cell is comforting the green one on the thumbnail
"It's alright, you still haven't metastasized"
Hi Trace.........
Can you make a video on stylus? difference between active and passive stylus. How they are made
Fun fact there is also research not only to prevent cancer but to extend human life to an almost indefinite point.
this is so reassuring.
why Dnews changed to seeker ?
My grandmother did NOT smoke, and still got lung cancer
I wonder if they found a cure would they even share it
if we increase our immunity system Then it can be prevent?
interesting number bro.
What is the background instrumental music in this video? it's really nice, if someone could please help me out!!
Then what is the internet?
So this is true for most animals?
we technically have a cure for cancer
and taht would be your immune system
yes, I know your immune system won't help if you have enough cancer to be diagnosed with it. but you make from 3-5 cancerous cells a day (note: all I'm saying is from memory, so there may be some errors in what I say in between lines). so if we could somehow overcharge our immune system, we may be able to cure some cancer.
although I cannot confirm that it'll work.
I can say, it's a thing we should look into (if we haven't yet)
Lonley Eagle I think they're working on getting the immune system to attack things like resistant cancer cells and Alzheimer's plaque forming cells. Some kinds of cancer cells can disguise themselves so the immune system will leave them alone. And since they're actual human cells they can evolve and no longer be susceptible to something that killed them before. Sneaky little bastards!
They have looked into it (we learnt that in school). Search "Magic Bullets". But there are problems, and long story short, it's not working right now, but will in the future.
Chatura Muthukumarana as suspected
I was correct
And I knew that it wasn't really working, yet
leeleeturn if they evolve, WE'LL JUST HAVE TO ALSO EVOLVE!
but that doesn't happen overnight (technically it does, but not in the way we want)
If I could reduce my risk of an unwanted early death by 40%, I'd certainly want the how of it! 40% is big in this arena. Nothing to discount as "No Big Deal." My god, what people would do just to save 40% of a leg for example. We're talking our life here!!!!!
Nice thumbnail. lymphocytes attacking a cancer cell, correct?
Do all types of food mess with DNA?
sometimes i feel, m only alive to see dnews(seeker)
The cure for cancer would be regular full body CT scans to detect early cancer but it is too expensive and probably holds a lot of risks.
Memes are the cause and cure for cancer.
this makes me keep smoking lol
When I think of curing cancer I think about the disease and how long it takes to "cure" and how difficult it is to become healthy again. I've never thought we would rid the world of the chance to get cancer, just be better at treating its symptoms and restoring a person's health quicker and less invasively.
YES Trace is back!!
No loyalty inside my DNA smh
did you really have to dumb it down to this point to get the skulls full of mush to pay attention? I also love how it's only tobacco smoke that bothers you. So if you're going to done this down let's dumb it down across the board
-insert cancer memes-
Hopefully those researching cancer are not going to keep the cure in a box and ask for money to use it.
Side note there is one central american country that developed a vaccine for lung cancer with high results. This vaccine is only available there.
Although the FDA finally allowed it for trials in the US (I think).
i want to help cancer patients. becuase i lose someone due to cancer.
Trace, please be in more vids
I would imagine that cancer would taste gross.
Would a world with no disease or sickness be good?.. It's a rhetorical question
Is there going to be something like dnews plus any more
Good to know that I have messed up cells in my brain 😜 brain cancer ftw.
do plant get cancer?
What is healthy living?
While it is true that cancer may start spontaneously, it does not easily proliferate. In order to grow and spread - the body needs to be compromised and likely subjected to foreign oestrogen.
I can't have cancer then because i got loyalty, got royalty inside my DNA
See this is why I think I'm going to get cancer, because I have really bad flaky skin around my eye brows and scalp, so clearly those cells are replicating a lot more than they should be
Sam Trott No, that just means that you have dry, flaky skin. Could be eczema or another skin condition. That's not how skin cancer works.
TRAAACE YOU'RE BACK
I like Trace's shirt. Earth is definitely the only habitation for mankind!
Incoming "The other third is caused by [insert name of stupid concept here]," comments....
Love his t-shirt!
That makes sense.
good video
whats the difference between cancer and mutation?
rtswift Not all mutations result in cancer but all cancers result in mutation. Mutations in DNA can also be good or neutral.
hmm maybe all this cancer stuff is a sign that our human species is trying to evolve
is it possible that its a mutation to lower the human population?
Cancer is a genetic mutation and these mutations are how evolution came about the is a stage where some cancers will survive pass on and mutate changing a humans physical form or appearance other cancers the most common ones are those that kill it is through failure that we became what we are today we just have a lot of other bad factors that we add.
Cancer ford?
Ohh i thought the answer was the youtube prank videos...
A flame that burns twice as bright will burn half as long.This is the price of being alive. One day, your time will come. Not because you did anything, but as a consequence of you merely existing.
From the earth you came, from the earth you took, soon the earth will take back, and with it your return. Time to die, and complete the cycle.
Very interesting.
that said forever chemicals are still disgusting.
I really wouldn't call getting cancer dumb luck
Am I strange to not want to marry and pro create with women who have cancer in their family history? If I find out there is a history of cancer in the her family, then I wouldn't even want to pursue her any more. I have worked in the healthcare industry for 3 years now and work closely with cancer patients. I know it too well how cancer can turn a patient and its family upside down. I noticed that A LOT of the patients have had cancer in their family history... I'm fortunate that my family's medical histoty is free from cancer. I just want do my part to keep the risk low for my future offsprings.
so can i now smoke ???
I'm guessing the other third is from fidget spinners right?