BLOSUM Substitution Matrix

In this video, we discuss the importance and the conceptual aspects of BLOSUM Substitution matrix.

[@mayank9986]

Great....I was unable to understand how to calculate the expected frequency...Nd you nailed it...Thnx

[@BioPandit]

You are welcome buddy... stay in touch and please share our videos with your friends...

[@skbmbgcalcuttauniversity1846]

Excellent one... could you also upload a video on BLOSUM-PAM comparison?

[@BioPandit]

Yes its located here: ruclips.net/video/3h58QOy1QfA/видео.html

[@priyadarshinisanasam7367]

Wanted to know what does the pam and block table actually explain?

[@ritasinha443]

very nice, thanks... :-)

[@meyyamuthu4438]

How do you get the expected frequency? Why is it over 576?

[@hui7303]

24 x 24 = 576; for Ab, exp freq = 14/24 x 4/24 x 2 = 112/576 = 7/36. p.s. look at the second row for AB in the last table