What are homeobox genes?

Homeobox genes are a cluster of regulatory genes that are spatially and temporally expressed during early embryological development. They are interesting from both a developmental and evolutionary perspective since their sequences are highly conserved and shared across an enormously wide array of living taxa. Most homeobox genes contain a 180-base-pair region called a homeodomain. The homeodomain portion of the protein transcript has been shown to interact with DNA in a cis-regulatory fashion during the critical stages of early body plan specification and embryogenesis. These sorts of interactions demonstrate the importance of regulatory genes and their architectural role in time-specific expression of DNA. Because almost all multicellular life forms share at least some of these common sequences of DNA, focus has been placed on discovering their evolutionary and developmental significance.

[@debbiehiggins3452]

Explained beautifully. Thanks!

[@andellahypolite]

❤❤❤ Very insightful and thought provoking talk

[@breadt0ast891]

Well done! This really helped :D

[@MyJ.x2]

This was so useful thank u

[@galaxieworld416]

i love your voice

[@GiacomoMilazzo]

What Bateson did in 1894? Did he identified the Hox genes? Are you kidding? The role of William Bateson, sure very important, was to build a very rich catalogue (Materials for the Study of Variation) where he described an entire series of "monsters" from the world, exceding part of the body, kind of appendix instead of other and so on. Bateson divided these anomalies in two groups: the first where the numbers of parts was altered and the second where a part assumes the aspect of another ((such as the famous legs instead of antennas in D. Melanogaster). Bateson called this last group with the name on "homeotic variant" (from greek, homeos, the same). Hox genes have discovered, and their role, only in the 80s of XX century,

[@danielhuck3571]

Lol, just shows we shouldn’t listen to everything we hear.