Can Transfusing Young Blood Reverse Ageing?
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- Опубликовано: 15 окт 2024
- Yes! Young blood DOES seem to have some benefits but...it's more complicated than that.
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I use the story of Ambrosia, the Silicon Valley startup that promised the fountain of youth in the form of a transfusion, to illustrate more tips and tricks of the pseudoscientific trade. Heterochronic parabiosis has some fascinating effects, but like with so much quackery, a tiny kernel of truth is extrapolated into something completely fictitious.
Plus this was an excuse for me to revisit Blade, Silicon Valley, Buffy, Interview with a Vampire, Sesame Street and of course the greatest of them all, Count Duckula.
References:
www.ncbi.nlm.n...
www.ncbi.nlm.n...
thewinnower.co...
www.ncbi.nlm.n...
stemcellassays....
Thees ees not episode *ooone*..AH AH AH. Thees ees episode *twooo*..AH AH AH!
This is the story of Ambrosia, the startup that promised the fountain of youth in the form of an IV, presented to illustrate more tricks of the pseudoscientific trade. As with so much quackery, a tiny kernel of truth is extrapolated into something completely fictitious.
There might be a bit of a gap till my next vid due to PhD commitments but just like cancer, I'll come back when you least expect it. In the meantime sink your teeth into a neck of facts with your free month at CuriosityStream at the link in description.
'nuther great vid, good luck on your PhD stuffs 👍
Is episode ooone the Apple Watch one?
Medlife Crisis Hey i found a really intriguing subject I think would be a good case to investigate. Orthotropics
While we are suggesting topics to debunk... if you get a chance check out a fanatic online called "Ivor Cummins". He's a chemical engineer that is obsessed with coronary artery calcification/fad diets and thinks that he has all the answers to chronic disease (of course). His particular mania crosses over nicely with your profession, I'd be particularly interested in a deconstruction of his ideas in a way that a lay person can understand (he has a tendency to beat around the bush endlessly but there is a reasonably succinct interview on the popular yet highly woo "What I've learned" channel). I ask because he keeps cropping up on health/fitness media that I consume, his biases meet mine it seems but it's way too big a stretch for me to be sucked in!
Lol
you really deserve more attention such quality jokes
Seriously? You're going to praise the quality of the JOKES?
Ignore the way my eye is now twitching. It does that whenever I see quality advice.
Smart, funny, sexy, no ring- why doesnt he have more subscribers?!
@@PraiseTheFSMonster Eugh, accurate as hell. Look at this guy go.
You have a very low bar for good jokes.
Give this guy his own Netflix show.
I would watch it!
I never missed a video
also with how creative his videos are, I bet he's got a few ideas
@@moustafamohsen Neither did I!
General knowledge and relevant specific knowledge together. What is not to love. Also a supporting cast of irreverent and irrelevant knowledge. And What we do in the shadows clips.
So I joined curiosity stream.
The writing quality of this is top notch, especially with all the (terrible) AMAZING puns :D
Yes.The purpose of the pun is to be as terrible as possible. That's why the pun is the highest form of humor.
I bet he's got kids. Why tell a bad joke when you can tell a dad joke?
Eugene Motley I hope he does have kids, great genes
Watch your children closely least they disappear
This seems like a very useful video to point people to in general about how just because "they did a study" doesn't mean you can trust their claims. Going into how to skew the results in your favour that way does so much more than many times I've seen people take apart bad studies. Especially the part about ordering so many tests but not focusing on the outcomes of all of them.
I got a good laugh out of this. Statical Jerrymandering is what one of my professors called it. (when you build the study to favor the results you want to get)
Oooooh I love a good take-down video. (Hey wtf my channel doesn't have anything to do with being blind. I was just blind drunk. Fake news)
Heh, how do you know I was referring to you? OK I totally was but I needed to make a joke out of it. btw this isn't at all the thing that I mentioned I was planning, I actually need to learn how to animate for that. It might take...some months.
I accidentally wrote “take-off” instead of “take-down”. Planes always on the mind 😅
@@RealEngineering I just figured it was some Irishism I wasn't familiar with
Even one have one like in this comment section😸. (thanos seen happy)
@@RealEngineering what a legend
I was searching for ecg interpretation tutorials and RUclips started recommending me your videos. Couldn't be more grateful haha
As a registered full member of the Comment Reading Association of the People (CRAP), I'm only here to read your comments. Please keep the comments short and succinct. We do appreciate your typing efforts and value your well-thought out responses. We only ask of you to please be mindful of correct spelling, grammar, levels of diction and syntax. Thank you!
Mo1Ya
Too funnieee and well said 👏👏👏👌🏽
Yes I would like to register CRAP.
I don't know why it sounds funny.
piss off chap
Just a minute here!
What happens if you forget to pay the sin tax?
Yes we'll also continue our co-rekt spelling, grandmas, and high levels of dick-shunning.
Shot and so sinked.
Speaking of questionable studies done on mice, and applied as theoretically valid for humans.
I watched a video many moons ago, about Hydrogen Sulphide induced metabolic stasis.
It said that it could be used for:
a) long duration space travel
b) pausing a person in a critical condition (heart attack, stroke, physical trauma), so they have a better chance of surviving the trip to hospital where better care is available.
I haven't heard anything of it since, but maybe it could be an interesting topic for you to explore?
Its funny because hydrogen sulphide kills you.
@Araki Hisahsi so can oxygen or just about anything else. Everything is a poison, it's just highly dose dependent.
@@Jake12220 Yes but inhaling a regular amount of oxygen doesn't kill you, drinking hydrogen sulphide does.
@@holyravioli5795yep if you drank hydrogen sulfide you would certainly die. Drinking anything that needs to be -60 degrees Celsius to be liquid would, let alone liquid farts(it's also known as rotten egg gas and a common cause for the bad smell of farts).
It's honestly an interesting chemical, harmless at low doses, very smelly, but certainly has killed. Honestly, the last time my dog farted in the car lm surprised l didn't die, at the time l was kinda wishing l would....
@@Jake12220 Ok obviously anything will kill you given the right circumstances but the real question is why would anyone consider drinking hydrogen sulphide, let alone think it's healthy.
That was actually an interesting way to solve the problem of pumping blood for a patient. Parent does it for the child. Glad we have pumps now, but that's genius.
One thing about living in Silicon Valley I never could stomach-- all the damn vampires.
you are right next the other big EDU youtubers, your stuff is amazing. Love it all, looking forward for another great vid!
I am sure he's gonna blow up like a few of the other channels I have subbed to. I watch Project farm grow from just over a few thousand subs to over 200k in a year.
Just wanted to say that, as a night shift healthcare worker myself, I didn't know how much I needed a relatable youtube channel like this one
This channel is soooooo underrated 10/10 would succ again
Love this channel... I can't understand how you are not still with at least ~200k subscribers. Keep up the amazing work!
It takes time to grow unless you have a random viral hit... He's well on the way
My take away: Wait a minute, Buffy was named after a component of blood?? Damn that's clever.
Another great video, thanks. Those clips from "What We Do in the Shadows" brought back some funny memories.
Best wishes for your PhD work. I lived in the UK 1985 to 89 doing my PhD. Thirty years of being back in Australia and I'm still not allowed to donate blood because of the Mad Cow thing. There seems to be a link between PhD and blood transfusions. I think it's worth a medical trial.
Fantastic video as always! There's also another point of controversy that you din't cover, but one of the major players in this field of research, Dr. Amy Wagers, published a landmark study a few years back into identifying one factor, GDF11, they determined might be crucial in mouse parabiosis studies, needless to say it hasn't "aged" well. With retractions, conflicting studies, and as of late, research indicating that it might actually induce muscle wasting. I do believe there are circulatory factors that might dampen some aging effects, but like the other newest biotechnology innovations like stem cell implantation and CRISPR modifications, there's a long line of charlatans waiting to swindle, deceive, and mislead their clients and the public.
Can you please cover mewing and whether or not it genuinely works?
the facial restructure part is absolute bs. the tongue and jaw posture however do tend to look better than just closing your jaw
Oh yes this
what is mewing?
h ch google my friend
Gru look at before and after pictures and make up your own mind
I always wonder how people just figure out that they'd be great for RUclips. Because, honestly, you're a natural at this.
I'm ashamed to say that until now I was almost sure that it actually worked.
I need to be more critical of such claims in the future.
you made a pretty compelling argument for curiosity stream, so i used ur link and started a trial
Yay! Thanks, sincerely. I was a bit nervous doing my first sponsored vid but they were so nice and supportive. Definitely helpful for creators. Hope you find it useful!
Thank you!!! We hope you enjoy our service! And, yes, he is a pretty awesome salesperson :)
@@CuriosityStreaming hehe yupp
Count Duckula! Very fitting choice
Thanks for the upload. I recall about ten years ago reading about research in Mexico transfusing blood from donors 16 years or younger into senior recipients. The scientist predicted that a novel blood protein was responsible for the rejuvenating results. Then a few years later back in 2016: probably May - July; two separate research groups reported preliminary findings one of which was a Japanese based group and both had successfully identified a protein responsible for the effects. However more research was reported as been needed by the principle investigators.
"Cross circulation" That whole using an adult's circulatory system to take over for a child's during surgery is kind of beautiful.
I met one guy when I lived in CA who claimed this worked. He was nine years younger than me and looked like my older brother. I didn't point it out to him.
Another really interesting video/topic. Thank you 'sir' for taking the time out of your busy life to put these out to the masses.
56k subs!! I remember the time (not so long ago) their were only 'us' couple of hundred. Please keep them coming and you'll hit your first big RUclips 100k achievement easily! :-)
Hey your videos are awesome, for the past week or so I've been telling ASAP science and SciShow that they should shout you because those people would enjoy your content. Also you're pretty funny haha.
"Some people dont benefit from oxygen"
I wholeheartedly agree
Mainly the deceased.
I feel like everyone does benefit from oxygen...
Also, love your videos.
My grandmother doesn't require any oxygen whatsoever actually.
people who learned about free radicals: well actually...
@@kuhmuh2357 sure, but free radicals kill you orders of magnitude more slowly than oxygen deprivation, so...
@@Eddy-dn1jx I'm sorry for your loss and I applaud your ability to joke about it!
Since my 70th birthday, I have been transfused twice, each time with a pint of blood, and each time for valid medical reasons (or so I am assured). The blood was not selected to be from younger people, but hey! What are the odds? I’m now every bit of 72 years old, and no younger for the experience.
Hello Rohin, would you mind making a video covering the studies that have been conducted on Wim Hof and his breathing method ? I am really curious if the claims about his/ the methods ability to fight of serious disease are true. Could you also talk about the method itself and possible health risks, considering that it involves hyperventilation (at least thats what it seems like to me)? Thank you :)
Absolutely Genius!! Love your work, your EBP is on point, would love a video on a comparison between different kinds of diets and the effects on the Circulatory system.
Ps. Keep up the good work, a smile a day keeps some doctors away :P
This channel is a gold mine, especially for aspiring medical students like myself. TAKE MY SUBSCRIPTION.
I could not look away from the scenery behind.
I love the concept of ideas thrombos...ing? That opens up a world of possibility for us writer types. I say let no word in no field be too technical or niche to be applied to conversational topics!
Maybe you doctors have been doing this for some time and I'm just catching on! I want to hear some more instances of diction infused into unlikely host subjects!😁
I thought if a person get frequent blood transfusions it can increase the risk of rejection and cause graft host disease because of tissue differences. The ABO system isn’t the only blood type system. If a person gets blood transfusions often they have to do more accurate tissue typing because the body will start rejecting the blood if the tissues don’t match.
I love a good Count Duckula Easter Egg.
"Fangs, but no fangs" . Definitely worth following !
Doctor reacts to 19hr neuro surgery, why is that not a real video?
Sergey tinldw because they did surgery on a grape
@@tigerheaddude ruclips.net/video/AeeA6u3-LJg/видео.html
"He's made a right mess of that kidney."
Very witty. A joy watching it.
In a year, This guy will be close to or blown pass the 200k subscribed mark if he keeps this up.
Not quite, unfortunately.
I'd be really interested in your take on the other anti-aging technologies currently in research.
Senolytics, etc.
Especially with regards to the SENS-approach of Dr. Aubrey DeGrey.
Thank you for all you're doing!
A study I really would like to see is the placebos effect of reverse aging!
Placebo can do the most amazing thing and why not reducing some of the ill effects by aging?
4:10 I hate to "b negative" here...
Wonderful.
That's my blood.
Just found this channel!
Its great! So heres not only my gratitude but also my immense respect * magic respect transmission *
Recently came across your channel super impressed with your dry whit and knowledge. I also love sci fi and the EXPANSE is awesome!!
Beautiful information. Love how you break things down and if you have to use medical terms, you explain them. The dry british humor is great too! Keep up the great work :3
Oh my god. I've just discovered your channel. What is this? What's with all the puns? Why do I love it all??
Channel name checks out
Parabiosis sounds similar to proboscis (the part of a mosquito that allows it to suck blood)
I feel the need to point out that Count Duckula is the only confirmed non-blood drinking vampire character of all you have used in this video.
He's a vegetarian & rather hated the sight of blood. Made him very sick.
Seems odd to have his picture next to so much blood info due to it but I suppose he isn't sickened by words so he should be fine :D
I'm a new subscriber & fan, your videos are excellent, your pun game is magnificent & I love all the geek culture you add in.
Thank you so much.
Count Duckula in the beginning is just... perfect.
"The idea hasn't Thrombosed" -> 1) I laughed too hard 2) I am snowflake triggered because I Thombosed too (in my brain, lucky, no stroke).
You have to be the third comedy doctor RUclips channel I've subscribed to.
And the best one.
(Edits for spelling)
Oh tell me the other two! Always keen to find other docs on YT. I met up with Dr Hope recently, if he is one of your two. Hopefully we'll make a video together some time.
@@MedlifeCrisis So looking forward to this!
Teach us how to research and find information effectively!
Thank you for that Grime reference.
Thank you for all the work you put into making this videos to inform people.
Imagine having a transfusion reaction from an illegal transfusion and having to go to ED to explain what you've done.
This is just the high quality medical humour I’m looking for!
This channel is so great
Spot on! Strong work, Doc!
I lived all my life to this point just for the „save blood“- roadman-moment xD
You're such a geek! Love your channel!
Love the use of Count Duckula in the intro.
*>_>*
*
We're born of the blood
Made man by the blood
Undone by the blood.
Not to mention fraudulent "clinical trials" specifically engineered to show positive results.
I saw the title and immediately search for BB reference, not dissapionted.
@@karolinakira8576 I just couldn't help myself. The sweet blood sang to me. It was enough to make a man sick.
So you're saying there's a chance...
Yes
Excellent, excellent, excellent- I just LOVE good information. Some trivia for you- Karmazin, it turns out, is a distant relative to P.T. Barnum, famous for the quote, "There's a sucker born every minute".... J/K. I have the same hot button: professionals who sell out are _____________. (Can't say, as this is a family show).
I was thinking this sounds a lot like Theranos, and two seconds later you said the same thing.
Good job. Lots of information and lots of humor. More.
You must have a team to find all the fun clips and art. Well done!
"...a company called "Ambrosia"..."
Deus Ex intensifies
i saw the results of this in 2001 - 2003 when they had to periodically give transfusions to my 80 year old grandmother. She was dancing around the room for two weeks when they did this,,it lasted a couple of weeks
Great background. Recently discovered your channel so catching up on past vlogs.
The whisper is that the young blood thing is big up the Mall! (Allegedly "One" has a pint of kiddie blood regularly). Seems to bring back memories of a rather more voluptuous Queen from the Hammer Stable. Anywho, great video sir. I don't see why you've had criticism, reminds me of the time I suggested to some Americans that if they didn't own guns on a wholesale fashion then the likelihood of being killed by one is drastically reduced. It was like i'd abused their dead grandmas! Common Sense, and why some hate it.
I'm so fucking happy to find out you watch Silicone Valley. Do you enjoy it? I spend 90% of my day preaching about it.
I love it man. One of the best comedies of the last 10 years. I spend 90% of my day shouting JIN YAAAAAAANG at people.
The real rich people also have strange addictions to blood related rituals. It's strange
Is that why children disappear???
@@melvinmaina4910 about 400k children disappear in the US.
I just saw the entire count duckula ...so much nostalgia
God damn it! That joke at the end made me laugh way too loudly!
Great storytelling. Sublime puns. I foresee generations of children rolling their eyes at your deadpan dad jokes. Thanks!
I just found your channel and I just love the humor and medical topics. I'm only a veterinary tech but I'm interested in everything from cosmology to...less broad topics. :}
always fantastic work (video). and some foolish people(extrapolating from a bad study)
also, GATTACA is great, but then I looked up when it released, and now I feel old.
Did you already know the trivia about the film's name? Probably but just in case - G,A,T,C...all DNA bases.
As a severe mutant hemophiliac (A) i can attest to bloods rejuvenating capabilities blaaaa.
(i know it's not the same thing, just wanted to make the lame joke)
(Hope you do an episode one day in this series about that doctor who is yet to do a head transplant)
Also shoutout to Duckula.
Oh god that dude! I've tweeted about him quite a lot, he's obviously insane but the thing that perplexes me is how so many apparently sensible journalists have bought his BS! Thanks, if he pops up in the news again I might well do.
He even looks like hes straight out of some X Files episode or an evil Bond villain (or from MGSV). I think it's intriguing in the sense that he Might go through with it regardless of success, we all know that medical history has it's dark side where we've been able to take leaps ahead by people doing far worse things to others.
Came for the info, stayed for puns
There's some nutter on RUclips who thinks eating babies and children reverses aging and hasn't had his channel shut down last I saw him, or demonetised (yet my videos on plants regularly do). Go figure?!
Your succulents are communist plants >:|
Are you serious?! Jeez Louise thank god I didn't find that during my research. All kinds of loonies on RUclips. I'm just an amateur loonie, these guys are pros.
@@MedlifeCrisis I think his channel is called sv3rige or something like that. He eats raw meat, stares at the sun, thinks the Illuminati eats babies and the world is flat. He has an unnerving number of subscribers...
@@tron359 very possibly my friend. Who knows what they get up to when I'm not looking
Alex
They must be plants of The herb kind that I like 😝😜
BLOOD DRIVES IN HIGH SCHOOLS! RICH PEOPLE PAY GOOD MONEY TO LIVE FOREVER
As a Wellingtonian I appreciate the what we do in shadows clips
This is a fantastic show.
Varies on just how hungry I am.... Nice.
Thanks Tom. ..
Hey, it would be great if you could do a video on all the science surrounding blood transfusions and donations as a sort of follow-up on this. I have hemochromatosis (C282Y), and in several countries around the globe I'm still not allowed to donate to blood as it is considered "tainted".
"my mini mental medical score test varies quite considerably based on how hungry I am" says the guy who's prolly taken 100000 tests IRL! Modest fella
This channel is great!
Bloody interesting.
Next they'll be stitching a teenager to Bezos. That'd be a pretty interesting horror movie.
My physiology lecturer had told us of this weird anecdote:
Supposedly, in China, as people rush to get on the trains, their heart rates and blood pressure increase, only to fall once they get on the train... hardly surprising, but apparently some faint as they're crammed into these trains as their blood pressure drops, but since they can't faint and fall over (because it's so packed), blood is unable to return to the heart and brain properly, thus resulting in some unfortunate deaths...
Bit weird, but thiught it may make for some good content for a video if you were to talk about it 😊
Gattaca scene? Oh fuck, you bet I'm subscribing.
2:50 seeeerum
7:37 ???
5:12 wait this all pieces together , frida inspired Fran Bow
I wonder how much I could sell my delicious, healthy young blood to these people for?
I'm amazed that this research would have required chancing upon in a TV drama and then research.