Long Covid research: Vascular and endothelial dysfunction

[@Feirin332]

I had my endothelial function tested at the beginning of the year (I have long Covid). It was at 3%. For comparison, endothelial function should be at least at 30%. My doctor told me I was at the same level as someone with late stage heart disease. I am lean, do not smoke, do not drink and eat healthily. I am in my early 40s. Long Covid did this to me. I treated micro clots in my blood with Nattokinase and serrapeptase and have been trying to repair my endothelium by taking Berberine, pine bark extract, dark chocolate and consuming a ton of blueberries. I made a big improvement in my symptoms until I got infected with Covid again about a month and half ago. About three weeks later I started feeling my health deteriorating again. Now I have to slowly build myself back up again. I can't seem to get ahead of my symptoms because I have been getting infected with Covid about twice a year since 2020, each time starting the cascade of symptoms again.

[@longcovidontheshort]

Sorry to hear about your recurrent infections Amelia. Nattokinase also helped me quite a bit, it's definitely something worth giving a try. Wishing you the best continuation possible going forward!!

[@candyland8903]

Same here!

[@denda2643]

May i ask for What biomarkers you were tested to test endothelial dysfunktion? Keep doing your Protocol, dont get too discouraged, it sounds very promising. Kind regards from germany!:-)

[@eddie8489]

How did they test you for endothelial function?

[@Mau365PP]

Would stem cells or exosomes help repair the endothelium? 🤔

[@YogaNinja1979]

Great video. Looking forward to the autoimmunity one. I have an appointment with a rheumatologist coming up. I’ve had long covid for nearly 4 years and also cannot improve due to keeping catching the virus and getting serious crashes if I exercise or do too much. I’m 44 and very healthy, used to hike before this. Miss walking more than anything. Some of the worst symptoms that I can feel are in my legs and arms and muscles. I do think this is vascular damage effecting the oxygen. I have found increasing nitric oxide by drinking green vegetable juices and doing wim hof breathing helps but I’m mostly too weak to do this often enough. Good luck to everyone trying to figure this out. So great to see the community getting together and supporting each other and great videos and content like this guy!

[@jamesneilsongrahamloveinth1301]

Am I right in thinking that people who keep catching the virus are unvaccinated? Vaccination is supposed to protect one from the disease . . .

[@ciuffoarancione8929]

In the meantime you did jabs?

[@internationaltax7708]

Thank you! Vascular dysfunction certainly goes a long way toward explaining my problems with long covid. I have observed that there is a tipping point (for lack of a better word) of exercise: going beyond that point triggers cascading symptoms, disproportional fatigue, and far longer recovery times. The exercise duration/intensity to hit this point varies, but has improved slowly.

[@user-hb2gx1hi8b]

This comment describes my experience too. I've gone from riding or swimming 3 times a week to once every couple of weeks and never knowing when I'm going to have a bad few days where I can do nothing. It's been 18 months now. Feels like I turned into an old man overnight.

[@yestedayssolutionstotodays816]

This phenomenon is called Post Excertional Malaise, or PEM for short. ‘Pacing’ helps to manage it (well, it helped me, nearly 2 years Long Covid and it has helped others with long covid and chronic fatigue syndrome). Please, google these terms if you have not come across them before.

[@epepelel7389]

Blood thinners & pycnogenol to help repair the endothelium helped me a alot.

[@royalfamily3076]

What type of blood thinner?

[@foxclover6]

​@eliquis
yalfamily3076

[@natalielynnb4778]

I agree that was well produced, and explained in layman terms where the general public can understand what’s happening I didn’t see your link for the referenced papers if you could provide that please also, if you have any knowledge of current information for treatment my daughter is a long Covid sufferer for three years and she is all but throwing up her hands on what to do I wish we had local and regional long Covid clinics that actually provide immediate help… we are in the Seattle area. thank you for all you do.

[@longcovidontheshort]

Hi there, thank for the kind words :) You should be able to see all the references at the end of the video description. I am really sorry to hear about your daughter... From my understanding in Seattle there's at least one Long-Covid care facility from the University of Washington -> more info here: www.uwmedicine.org/specialties/post-covid-rehabilitation. I hope they can help you regarding some form of treatment. Unfortunately the situation is complicated, as you surely know, but there are a series of treatments that can help if (and most likely only if) your daughter's Long-Covid presents with symptoms from other known syndromes. See this nice consensus paper: onlinelibrary.wiley.com/doi/10.1002/pmrj.12894

[@andrewyeager9786]

Ever since I got over COVID-19 I have had really bad insomnia. I can't sleep, I even take sleeping pills and it takes me at least two hours to fall asleep, or I sleep about four hours wake up and can't fall back asleep. I also don't have my energy levels back to normal yet.

[@markday6953]

Hey, I have had a similar problem and still struggle with it. In case it helps, I have noticed that increased sodium (vs. potassium) during the day will help me fall asleep - I have found I need way more sodium during the day then I previously did, and need to watch how much potassium I get.
Another thing that may help with getting up in the middle of the night and not being able to sleep is to try a low histamine diet. Apparently, covid can cause histamine intolerance in some people.

[@ciuffoarancione8929]

Most cases of long covid comes from the jabs or jabs and then covid. And doctors know it very well. My life is ruined after 2nd dose of pfizer... Was really fit and healthy...

[@robinfallentine]

Yes.😊😊

[@mojabaka]

same. my life is over since I was 24. I'm 27 now. I actually want to kill myself for everyday for the past 3 years, but I'm a too big pussy to do it. I know for a fact that there will never be a cure for POTS and neuropathy.

[@nickdriver8337]

These videos are really great, wish you would make more!

[@sallyweiner4180]

Thank you, excellent reporting. I’ve been able to walk however tried yoga today and it wiped me out

[@bg5760]

Encourage all to look into mesenchymal stem cell IV infusion. It was tested on severe Covid and long Covid patients with good success but not yet dialed in.

[@stephenbradshaw5311]

Thank you for the video, I have been treated twice with HELP Apheresis after a reinfection and that has brought me back to life by removing all the micro clots from my vascular system, the challenge is wether the fix is permanat given the damaged caused to the endothelium. At present im fine but only time will tell.

[@annaberger6253]

Where did you do the apheresis treatments?

[@ResetTutoriales]

how are you doing rn? are you still fine?

[@stephenbradshaw5311]

​@@annaberger6253Cyprus

[@stephenbradshaw5311]

​​@@ResetTutorialesI am fine and have a normal life as long as I pace carefully.I do have however take clopdogrel 75mg and aspirin and nattokinasse to keep blood from reclotting

[@MyLongCovidAdvocacy]

Well done, thank for taking the time to produce. I re-posted to give it a boost for you.

[@michaelchapman7627]

Thank you so much, this has been very informative. Appreciate the sharing of knowledge in layman terms.

[@johnmaggiorino4493]

Ciao Grazie👍

[@thistree9028]

Thank you for considering this, some type of disjunction with this..thank you. Now I must go to sleep

[@jsquire5pa]

You’re confusing science and medicine .. two very different things .. as we are finding out with the near total failure of medicine to improve human longevity in the last 40 years … medicine is largely hot air

[@ResetTutoriales]

thank you for your work man, i see myself in you u.u

[@rahulsharma369]

Covid Long hauler should try Glycine and taurine, may be choline

[@derrickpromislow9210]

Thanks for the great video. This seems to describe exactly what I’m suffering from. After a bunch of testing I was diagnosed with CNS Vasculitis, damage/inflammation of the small vessels in my brain. The immune suppressant they put me on didn’t help. I’ve had the vaccines and have had Covid and still test positive for it now after almost 5 months. My doctors have no ideas. Can you provide sources for this info so I can try to inform my doctors and get treatment before it’s too late? Any suggestions on treatments?

[@derrickpromislow9210]

Yes, this is quickly damaging my blood vessels in my brain causing strokes, so any help is appreciated

[@derrickpromislow9210]

Yes, I found the your references section. I will forward to me doctors, who probably won’t investigate. 😢

[@LYJManchesterUnited]

I have long covid, how do I recover pls help

[@kylem8117]

Are these vascular biomarker tests easy to get and what type of doctor would be able to order these tests and provide treatment?

[@longcovidontheshort]

These vascular transformation proteins are not widely available for testing in clinical/community laboratories. They are mostly used in research settings. The point is that they might be useful for clinical trials. Also regarding treatment it's complicated. There are drugs that modulated HIF-1 but I think a clinical trial would need to occur first

[@alias701]

When does the new video on autoimmunity come?

[@artssite24]

so whats the cure or treatment ?

[@emaarts2997]

Could this thinning of the blood vessels cause PN in the extremities? Hands and feet.

[@theancientsancients1769]

Im wondering if you have or had long COVID? Hypoxia makes not sense for all because some had very mild covid yet got long covid . But generally more oxygen tends help long covid people

[@longcovidontheshort]

Yes I have Long Covid, I mention this in my first video actually but maybe one day I will make a video of my own case (after many videos that are waiting in line though). I guess you're mentioning Hypoxia due to the HIF-1 pathway. Your body can enter an hypoxia or hypoxia-like state without you noticing. It was common for many people with Covid to have low SpO2 without experiencing any type of dyspnea for example. If you check my previous video on microclots it might also help to understand how your body can experience local hypoxic conditions

[@davidmangen1912]

Prednisone for covid. Works great!

[@rahulsharma369]

But what abt long COVID?

[@nevsart5884]

Is there anything like a cure yet or we still groping in the dark?

[@longcovidontheshort]

There is no cure that has been approved for now. But not having a cure does not mean that we are completely clueless. Research is starting to uncover very interesting aspects, it is start to get all these theories linked together, and there are interesting clinical trials which I intend to cover in some of my next videos.

[@nevsart5884]

@@longcovidontheshort Thank you and excuse my impatience but I have been bedridden 80% of the time for the last three and half years, I know there’s many more like me, we are going through a living hell every day, whether we have people to help or not it’s extremely difficult, the medical profession, in my case, have been next to useless (UK), all my teeth fell out early on in the illness. I know they have been those with Long Covid that have taken their lives due to the difficulties endured. Every time I see a thumbnail or heading with something similar to Long Covid breakthrough, I get my hopes up………. It’s literally torture to realise it’s yet another medical hypothesis. I’m not ungrateful, just frustrated beyond belief!

[@longcovidontheshort]

@@nevsart5884 I am sorry for the suffering this disease has brought you. With regards to my channel, just know that it will always be about research and medical hypotheses, but these are not "new". They have been investigated for quite some time, and real progress is being made. I think the next couple of years will be very revealing. Yeah I know "2 years" sucks to hear - same for me! But it might also be faster. Hang in there! 🕊

[@nevsart5884]

@@longcovidontheshort I always have hope……….. not knowing if I’m ever going to get a better has left me with questions like, when will I need to go into assisted living? If there’s a possibility in two years, that’s something………..

[@jipa3883]

Same here. 3,5 years in and no help. Living in Sweden. Completely handicapped.

[@patrickcollins4462]

What's the difference between long COVID and vaccine related injuries?

[@YoYoCoCo777]

Nothing... they are trying to bury the damage from the clot shot!

[@emaarts2997]

I am suffering from 'long covid' and I never had the shot.

[@rosschambers1987]

Any updates please?

[@raloufen4292]

Where to go for help? Which Dr knows how to treat?

[@SuzanaMantovaniCerqueira]

🤔

[@YoYoCoCo777]

Long Covid? Bull crap
It's damage from the clot shot!!!!

[@GungaLaGunga]

No. Take a deep breath, and realize, people who were never vaccinated are getting infected, AND getting long covid too. Oops. Good luck.

[@katebehrend9783]

Not sure if you’re just trolling for the sake of it, but a large proportion of Long Covid sufferers developed their illness following Covid infection long before any vaccines were rolled out.

[@foxclover6]

Plenty of people got it without getting the shot. So no.

[@max-cs9ko]

Blood thinner are extremely helpful, Long covid has something to do with vague nerve but whatever the case long covid just shows failure of Allopathic medical system, they just have a lot of worthless research papers and word play, they have taken some month to create vaccines which was unimportant for most people as most of us already developed normal covid immunity but they are failed to provide any medicine for long covid which is much more serious

[@jamesneilsongrahamloveinth1301]

Could it be that some of those diagnosed as suffering from Long Covid are actually suffering from the after-effects of the vaccines . . . ?