The action of a self-test for rupture of membranes

This test is based on an immunoassay for alpha-fetoprotein embedded in a sanitary pad. The leaking fluid is absorbed into the sampling region and spreads by capillary action along the immunoassay test strip. If both control and test bars appear, the assay is interpreted as positive for amniotic fluid leakage. If only the control bar is visible, the assay is interpreted as negative for amniotic fluid leakage, and therefore, the leaking fluid might be urine or semen. See the related article by Mor et al (August 2016 issue; bit.ly/2a56OHJ). Video created by Dr. Amir Mor. Used with permission.