Understanding Pernicious Anaemia (B12 Deficiency)

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  • Опубликовано: 18 окт 2024

Комментарии • 180

  • @aleesheee
    @aleesheee Год назад +23

    A lot of people here are having huge neurological issues and brain fog/ confusion which makes things harder to grasp when our brains keep shutting off and personally I have vestibular migraines too which completely disable me for weeks, so I really appreciate the pace of the author and the free information 🙏😉 I just wanted to share my thoughts and give thanks, blessings and healing to all who are struggling ❤

    • @mrgringo7289
      @mrgringo7289 4 месяца назад

      I had to put on 1.25x lol

  • @ananya5679
    @ananya5679 3 года назад +10

    JUST CAME I ACROSS THIS CHANNEL...AND I AM ABSOLUTELY LOVING IT!!! Although I am high school student but I still just love watching these videos....amazing explanation!!! Thank youuu

  • @UpgradeyourHealth
    @UpgradeyourHealth 7 месяцев назад +2

    This is amazing! I was just diagnosed as a adult, so I'm striving to absorb all the knowledge I can gather.

  • @rahulrahula4527
    @rahulrahula4527 3 года назад +11

    Your videos are criminally underliked! Brilliant levels of detail and clarity of explanation. Very happy!!

  • @sinepsis9578
    @sinepsis9578 3 года назад +37

    Love this! I was recently diagnosed as a young adult, so I’m trying to learn everything I can!

    • @charlyrogers5711
      @charlyrogers5711 2 года назад +4

      Same! Can you describe your symptoms for me? Curious to see if we all match up. Also, how are you feeling now?

    • @sinepsis9578
      @sinepsis9578 2 года назад +8

      @@charlyrogers5711 Of course! My pernicious anemia developed as result of Malabsorption Syndrome and is comorbid with gastric disease, so I have a lot of gastric symptoms like nausea, vomiting, abdominal cramping, and severe weight loss that may not be caused by the anemia, but CAN be. The doctor thinks they are exacerbated with it in my case. I also experienced extreme fatigue, dizziness, loss of balance and confusion. It was these symptoms in particular that got our attention. We did a blood panel, and my B12 measured at 82 pg/mL. I now do weekly injections of 1000mcg and as of three weeks ago have a B12 level of 212 pg/mL. I still suffer severe gastric symptoms but do have periods when I’m much better. I am still a bit unsteady as well but the other neurological symptoms have disappeared. How about you?

    • @sinepsis9578
      @sinepsis9578 2 года назад +2

      @@vapemcvaperson I’m so sorry to hear you’re struggling as well! Ironically, I’m about to start seeing my doctor for routine examination because of bleeding as well. I have Cyanocobalamin 1000mcg and use sterile single-package syringes to inject it weekly. Have you looked into seeing if you may qualify for free health insurance? I know it varies as to where you live/your situation, but if you do end up ordering it, please check into the company! I would still purchase my syringes from a pharmacy vs ordering so you can ensure they are sterile and not broken.

    • @ghanshyamjagada6643
      @ghanshyamjagada6643 2 года назад +1

      What was your b12 level when diagnosed?

    • @sinepsis9578
      @sinepsis9578 2 года назад +3

      @@ghanshyamjagada6643 57 - I am proud to say I am at about 400 now after months of weekly injections.

  • @graceusa3942
    @graceusa3942 3 года назад +11

    This teaching is simply, clearly, easy to follow and the best. Thank you .

    • @binathere2574
      @binathere2574 Год назад

      But testing does not always reveal true condition of the patient. It's best to go by symptoms. Treat the patient not the numbers.

  • @esterherschkovich6499
    @esterherschkovich6499 2 года назад +40

    Excellent video(I am a Nurse) I have Pernicious anaemia 😑the injections are not enough 🤔I take B12 sublingual they are brilliant but I suffer..Bad mussey headaches,totally drain,face looks white+breathing problems...to name a few..have this now.Fatigue too.

    • @jk9719
      @jk9719 2 года назад +3

      What dose do you take for the sublingual b12?

    • @lovelyrics3656
      @lovelyrics3656 2 года назад +1

      Same here

    • @mihaeraaboud9548
      @mihaeraaboud9548 Год назад +4

      May god heal you💗💗💗🥺🥺🥺

    • @brasshound4442
      @brasshound4442 Год назад +2

      My doctor had me stop taking the extra B12 and shots I was on and just do the 1000mcg she recommended. A year later and I've been in agony not knowing what happened, tested for everything, and finally just took my 10,000mcg of sublingual and instantly felt some relief. I suffered so much for no reason. I'm going to demand my injections again.

    • @ScarlettDuchess
      @ScarlettDuchess Год назад +2

      I have autoimmune PA too. I do great on 2000 mcg daily of sublingual B12 spray. I only had 4 B12 injections before I switched over to sublingual. So much better! I’ve been on sublingual daily for 14 years. If I stop my B12 spray then symptoms start coming back in a day or so.

  • @floorgang5027
    @floorgang5027 3 года назад +11

    Sir you are doing a great job thank you for making these concepts so easy to understand !!!! Thank you ☺️☺️

  • @mariaraluca4744
    @mariaraluca4744 Год назад +2

    Finaly it makes a lot more sense!
    Thank you, Tom!

  • @B3bita1215
    @B3bita1215 3 года назад +9

    Absolutely amazing explanation. Thank you!!

  • @manarsmaan2624
    @manarsmaan2624 3 года назад +5

    Can you make video on other kinds of anemia . Thank you so much, it is very helpful and great explanation

  • @michellecheatley1214
    @michellecheatley1214 Месяц назад +1

    Nice Guideline have made a few changes to the treatment regime as of March 6th 2024 in the UK...

  • @ScarlettDuchess
    @ScarlettDuchess Год назад +3

    I have autoimmune PA with both intrinsic factor antibodies and parietal cell antibodies. I need B12 daily! I first was given B12 injections once a week. A terrible rollcoaster of feeling better then feeling worse. Ugh. And the side effects of an acne rash over my face and chest (took 4 months to go away after stopping injections) and shortness of breath.
    I switched to sublingual to see if that worked and wow! amazing!! I use 2000 mcg bioceuticals sublingual B12 spray every day. I could not imagine going 3 months without B12. 🤯 I once did not have my spray for 3 weeks. OMG!! Horrendous! The most insanely severe unliveable brainfog, extreme fatigue, white spots started reappearing on my forearms again, body odour….etc. Within 5 minutes of taking my B12 sublingual spray the brain fog disappeared. My God the relief was intense!!!! 🙌🥳 But after not having any B12 for 3 weeks I had a headache as a side effect for a few days.
    Whoever wrote the treatment for PA is B12 every 3 months needs to a good kick up the…lol

    • @binathere2574
      @binathere2574 Год назад +1

      It's not possible for someone with PA to absorb sublingual B12 you don't have the ability to absorb if you have intrinsic factor antibodies or parietal cell antibodies . Something is not correct in your diagnosis.

  • @bobbyjoe8900
    @bobbyjoe8900 Год назад +9

    Was diagnosed with Pernicious Anemia. Was told that you can't over take B12. What your body doesn't need it will get rid of. Through your urine.

    • @Chozenfew73
      @Chozenfew73 6 месяцев назад +1

      just a quick question, did your diagnosis get picked up in a random blood test or were they looking for Pernicious Anaemia to start with ? Thanks

    • @bobbyjoe8900
      @bobbyjoe8900 6 месяцев назад +3

      @@Chozenfew73 Went to the emergency room. I had passed out and was going to the ER to find out what happened. Through all the tests they found out I was completely out of B12. I was in the hospital for four days.

    • @oak5261
      @oak5261 Месяц назад

      Did you have an endoscopy? you need one because you probably have Atrophic Gastritis

  • @dannif6479
    @dannif6479 3 года назад +3

    Loving the consistency of uploads !!

    • @ZeroToFinals
      @ZeroToFinals  3 года назад +1

      Thanks - I'll keep them coming!

  • @sandrayates5446
    @sandrayates5446 Год назад +1

    This most helpful. I've recently been diagnosed low diabetes, low oxygen levels, low B12, pernicious anaemia, low blood pressure, pulse missing beats. Ive been prescribed Ferrous Fumarate 305mg, Folic Acid 5mg and Cyanocominn 50mg. Now I'm worried about taking thd Folic Acid. I think I'll have to talk to my GP about that, it's got me thinking. Ive still got all the symptoms as described in video. I've only been on these meds about 2-3 weeks.

    • @binathere2574
      @binathere2574 Год назад +2

      You need folic acid for Utilisation of B12 and you need B12 for the utilisation of folic acid. They work synergistically

  • @auroraveneziacarlislemakea8186
    @auroraveneziacarlislemakea8186 2 года назад +2

    Thank you so much for this video 💖 I am Pernicious Anaemia patient born with it and was given iron supplements for 40years instead of B12 ferinject or what you have written on this video

    • @rogerthat6221
      @rogerthat6221 2 года назад +2

      Can I ask what your recovery has been like ? A friend is dealing with the same thing rite now. She is 38

    • @thomassvensson1523
      @thomassvensson1523 Год назад

      Ferinject is iron

  • @nadinedavid139
    @nadinedavid139 10 месяцев назад +1

    Feel like forwarding this to my GP😢 thank you

    • @Maureen-vg7dx
      @Maureen-vg7dx 10 месяцев назад

      Tell ur gp to go to the pernicious anemia society uk on u tube all uk gpsdr chris steel from this morning they have videos of seriousness of this b12 deficiency pernicious anemia u can fone up pernicious anemia society uk as well have seen Charlotte's story on u tube its called Charlotte's story she sued the nhs with slater and gordon solicitors she's in a wheel chair now

  • @reaganscarborough3143
    @reaganscarborough3143 3 года назад +3

    first nursing exam tomorrow and this video really helped get the concept down !!

    • @Hydra_iiix
      @Hydra_iiix 2 года назад +1

      Best of luck for your future

  • @johnjackson8783
    @johnjackson8783 2 года назад +2

    Thank you for making this video. It's very helpful.

  • @kimsordyl
    @kimsordyl 3 года назад +3

    reading about this condition now, really nicely explained! Thanks :)

  • @NurseJacob360
    @NurseJacob360 2 года назад +2

    ya know, my professor is a genius and has a PHD in biology but somehow this my preferred method! thankss(:

  • @areebzahid8404
    @areebzahid8404 2 года назад +2

    very interesting knowlegde,thanks for making.

  • @MrJake11297
    @MrJake11297 3 года назад +2

    love this flurry of videos coming out in 2021! just before my exams haha

  • @MrSatheeshdent
    @MrSatheeshdent 3 года назад +1

    The best as for pernicious anemia

  • @goaway7272
    @goaway7272 2 года назад +13

    Great I was treated with folate first for years and b12 was ignored now I'm still on folate and was on b12 ingections monthly and have been reduced to 3 months which I think is a massive mistake I wish I could find someone who would actually help me fully.

    • @esterherschkovich6499
      @esterherschkovich6499 2 года назад +5

      Hi.I find the 3 monthly injections not enough and a real battle to get more.Your blood results say all is well but you still suffer with debilitating symptoms 😢 An anaesthetic Doctor I worked with recommended B12 sublingual tablets..Great help..Good luck.

    • @goaway7272
      @goaway7272 2 года назад +3

      @@esterherschkovich6499 its not enough after 3 weeks symptoms start returning I've tried sublingual and tablet neither do anything unfortunately but I'm trying a few workarounds I can not go back to living like that

    • @anthonyman8008
      @anthonyman8008 2 года назад

      This video doesn't help?

  • @Lifesciencebiologyworld
    @Lifesciencebiologyworld 3 месяца назад +1

    Excellent video

  • @michellecheatley1214
    @michellecheatley1214 3 года назад +10

    Example 1. 3 times a week for 2 weeks, then every 3 months, Standard NHS treatment. Example 2. Where neurological symptoms are involved, 1mg every other day untill symptoms improve at that stage ''you are more that likely self injecting, treating your symptoms as they arise & keeping them at bay.

  • @lapislazuli7876
    @lapislazuli7876 2 года назад +3

    Can you drink Apple cider vinegar in water during a meal? I thought we weren’t meant to drink while eating? Or is that ok? Or should the ACV be consumed just before a meal? Please advise.

  • @Pruzar14
    @Pruzar14 3 года назад +2

    The music changed ahahah.... ngl makes a nice change when im powering through listening to all your videos ahah!

    • @ZeroToFinals
      @ZeroToFinals  3 года назад

      haha glad you like it, it was time for a change!

  • @alexbarnwell6397
    @alexbarnwell6397 3 года назад +1

    Great video! Thank you for making these!

  • @thehungrynutritionist
    @thehungrynutritionist 2 года назад +3

    Could methyl cobalamin injections be used ? Would it be effective ? Does the dosing differ

  • @koshycherian7140
    @koshycherian7140 2 года назад

    Simple yet amazing

  • @poeticvilla8139
    @poeticvilla8139 2 года назад

    Very accurate n informative thankyou so much 😊

  • @tatendatakaendisa273
    @tatendatakaendisa273 3 года назад

    Great video, really informative yet concise.

  • @daudyusufirbad1940
    @daudyusufirbad1940 3 года назад

    Concise and clear thank you very much.

  • @chinthalewkebandara2358
    @chinthalewkebandara2358 2 года назад

    This is perfect. Thank you.

  • @TweetyPAK7
    @TweetyPAK7 Год назад

    I wish this went on a little more.

  • @humairaalam2226
    @humairaalam2226 3 года назад +1

    Very Interesting...😃😃 Thank you sir..

  • @yeseniaorozco8981
    @yeseniaorozco8981 2 года назад

    this was nicely explained thanks

  • @topperbooks2331
    @topperbooks2331 2 года назад

    This video is great!

  • @sayanss4
    @sayanss4 3 года назад

    Great as always!

  • @Emptywhitez
    @Emptywhitez 3 года назад

    Waooo great
    Can you plz tell me which app you are using for making the videos????

  • @nikkster01
    @nikkster01 Год назад +1

    bit confused I have had this for 25 years my first and only symptoms were just extreme tiredness all the time no matter how much sleep I got
    I manage fine with a 3 month injection only because the dr recommended it as keeping levels stable instead of yo-yo up and down

  • @asemabodaber7265
    @asemabodaber7265 Год назад

    easy and great ...thx

  • @larrainebrownlow4937
    @larrainebrownlow4937 Год назад

    Thank you

  • @medicmandan
    @medicmandan Год назад

    really helpful, thanks

  • @ha3we
    @ha3we 2 месяца назад

    Thank you sir😊😊😊😊😊

  • @chelseap938
    @chelseap938 Год назад

    Very usefull thannk you!!!

  • @Nocczz6
    @Nocczz6 3 года назад +1

    Great content

  • @lunawolf448
    @lunawolf448 Год назад +2

    I have it and I’m taking the pills for it. It’s 1000mg and it’s not enough. I get SO weak and can’t even get out of bed.

  • @generalpurpose772
    @generalpurpose772 4 месяца назад

    I’m B12 and folate deficient - waiting on the test for intrinsic factor to come back, but my doctor told me that I could start taking my folate supplement now. Why would she advise that if it might cause me harm?

  • @Doctor_DDrr
    @Doctor_DDrr 2 года назад

    جماااال الشرح🤩

  • @bwagner1722
    @bwagner1722 7 месяцев назад +1

    I have mtrr a66g mutation. White oatches on skin, no energy, ached and pains, numbness and tingling etc. , dr says im fine because my cbc is normal. What can i do to get my dr to take me seriously and actually investigate

    • @JodBronson
      @JodBronson 10 дней назад

      Low your homocysteine (Food). Then take Methylated B's Vitamins... B12 + B6 + Folate. It HAS TO BE "Methylated" or your body will not absorb it!
      NOTE: Methylated B's will also help lower your homocysteine level.

  • @alec1113
    @alec1113 7 месяцев назад

    You forgot to mention MTHFR MMA and homocysteine tests folate and folic are 2 different vits plus every 3 months for a b12 injection is extremely outdated , not one size fits all . 4 versions of b12 cyanocobalamin, Methylcobalamin,Hydroxocoblalamin and adenosylcobalamin

  • @jennyinthemorning
    @jennyinthemorning 2 года назад

    THANK YOU

  • @kushalbhardwaj3026
    @kushalbhardwaj3026 2 года назад

    Very nice...

  • @PinkFlowers365
    @PinkFlowers365 Год назад

    thanks a lot

  • @sharonborman6513
    @sharonborman6513 2 года назад

    Thank you🙏🙏🙏

  • @kushcloud420
    @kushcloud420 2 года назад +1

    Im having pins An needles right now it started yesterday

  • @Tonnie31
    @Tonnie31 3 года назад

    So helpful

  • @onlyonejupiter
    @onlyonejupiter Год назад

    Diagnosed a year ago been suffering horribly for more than 10 years I was taking once a week... I have next to no memory... my doctor is on leave and I need injections :(
    I have B12 dementia now

  • @fahad73453
    @fahad73453 3 года назад

    Nice video

  • @parintornnoonsang6989
    @parintornnoonsang6989 2 года назад

    love it!

  • @thefourthjhanagautama6583
    @thefourthjhanagautama6583 2 года назад

    But in case of oral intake how much should you take?

  • @dannif6479
    @dannif6479 3 года назад +1

    Can you cover acute abdominal complaints this year?

    • @ZeroToFinals
      @ZeroToFinals  3 года назад

      Yes, definitely this year!

    • @MsSilver41
      @MsSilver41 3 года назад +2

      Pernicious anaemia leads to severe abdominal problems hope this will be covered

  • @我爱猪肉
    @我爱猪肉 2 года назад

    the parietal cells at 0:56 kinda looks like among us

  • @Hydra_iiix
    @Hydra_iiix 2 года назад +1

    Very helpful 🤡

  • @23Fists
    @23Fists 2 года назад +1

    I only ever knew about iron-deficient Anemia, so thank you for the info! On an aside, can B-12 deficiency become a thing from over-using b-12 supplements/drinks? I know a few energy drink brands have like 300% daily value of B12, which I used to drink at least once a day for a few months, but then I passed a kidney stone that split my 'exit' wider (that was both painful and horrifying; thought I got but by a snake or something because I was working as an arborist and was relieving myself by a bush) and quit drinking them except but maybe twice a year, if I'm REALLY needing a pick-me-up..

    • @rogerthat6221
      @rogerthat6221 2 года назад +1

      That’s all they ever tell you. The doctors know and don’t want t to share

    • @binathere2574
      @binathere2574 Год назад

      It is not possible for B12 to cause toxicity. There is no upper limit according World Health Organisation

    • @Sandwich13455
      @Sandwich13455 Год назад

      Your grass snake split?

    • @Maureen-vg7dx
      @Maureen-vg7dx 10 месяцев назад

      ​@@rogerthat6221cos b12 deficiency or pernicious anemia is the cause of mental illness the depo is b12 shots or b12 oral liquid with folate liquid methylation

    • @Maureen-vg7dx
      @Maureen-vg7dx 10 месяцев назад

      ​@@binathere2574b12 and folate have to be level with each other

  • @عصاماحمد-ص6ك
    @عصاماحمد-ص6ك 9 месяцев назад

    Food is fish anx egg❤

  • @emma0llew
    @emma0llew Год назад +2

    This has worried me because I have both b12 and folate deficiency and they have most certainly given me folate tablets first without treating the b12.

    • @michaelmoores2654
      @michaelmoores2654 Год назад +1

      I have both too. You need the injection too as far as I know.

    • @emma0llew
      @emma0llew Год назад +1

      @@michaelmoores2654 I don't know why they haven't treated me for the b12 first. They seem to have told me the wrong info.

  • @rachel4339
    @rachel4339 Год назад

    Interesting that they don’t discuss the hereditary version.

  • @gopikrishnavenkatesh7923
    @gopikrishnavenkatesh7923 2 года назад

    Hi may I know that can neuropathy due to pernicious anemia can be cured ?. It been more than 6 months but still the numbness and pain is still not going .

    • @oak5261
      @oak5261 Месяц назад

      how is it now?

  • @sydneyhunt6681
    @sydneyhunt6681 2 года назад

    Are all 4 b12 IM types good for this

  • @notyourbells9584
    @notyourbells9584 3 года назад

    is that a new introooo

  • @motownr313
    @motownr313 Год назад

    Please help with suggestions. I am 62, diagnosed with genetic type PA 22 years ago with stomach cancer. Been cancer free after total gastrectomy in 2003. On cyanocobalamin injections since 2002. I have to get Injectifer every now and then because of low blood count. What can I do to naturally get whatever is in that blood building infusion? The treatment is very expensive. What other supplements help keep me healthy besides a b12 regimen with folate (or is it folic acid that i need?)

  • @elsagrace3893
    @elsagrace3893 2 года назад

    But what about methylmelonoc acid test??

    • @pepper419
      @pepper419 2 года назад

      Where did you get those eyes?

  • @Constans99
    @Constans99 3 месяца назад

    Methylcobalamin, not cyanocoblalmin. Folate, not folic acid.

  • @chandrashekharsharma5800
    @chandrashekharsharma5800 3 года назад

    Where to get this book in INDIA

  • @shashankshukla4297
    @shashankshukla4297 3 года назад +2

    Bro i have ulcers in my stomach and have problem in absorbing vitaminb 12

    • @bettyausten9533
      @bettyausten9533 2 года назад +1

      What have you been able to do about it?

  • @princessriemann5291
    @princessriemann5291 Год назад

    ❤❤

  • @hameemkhan204
    @hameemkhan204 2 года назад +2

    when he says "Pernicious anemia is the cause of Vitamin B12 deficiency anemia", did he mean it occurs because of vit-B12 deficiency?

    • @MichaelMerritt
      @MichaelMerritt Год назад

      Pernicious anemia prevents intrinsic factor from binding to b12 in the intestines, results in the b12 deficiency. The way he said it makes sense to me.

  • @mala.k4824
    @mala.k4824 3 года назад +1

    👌👌

  • @katarat544
    @katarat544 3 года назад

    Have textbook ?

    • @ZeroToFinals
      @ZeroToFinals  3 года назад +1

      Yes, you can search Zero to Finals on google or amazon to find everything 😄

    • @katarat544
      @katarat544 3 года назад

      @@ZeroToFinals i mean textbook pdf

    • @ZeroToFinals
      @ZeroToFinals  3 года назад

      @@katarat544 There is no pdf for the textbook, but you can find notes at zerotofinals.com/learn

    • @katarat544
      @katarat544 3 года назад

      @@ZeroToFinals @Zero To Finals thank you so much. I want to buy your book but i live in south Korea

    • @ZeroToFinals
      @ZeroToFinals  3 года назад

      @@katarat544 Oh, I see. Don't worry, everything is on the website so you won't miss out by not having the book. You might be able to get it shipped from amazon.com or maybe amazon.co.jp if you really wanted the physical book

  • @CallumAnthony-r9o
    @CallumAnthony-r9o Год назад

    You speak too slowly. I had to speed this up to 1.25x to make it sound like you were speaking normally.

  • @01123heavenlybe
    @01123heavenlybe Год назад

    Thanks 🙏 so much. 🗽🪩🎼🎶

  • @ماجدةالربيعي-ي4س

    Thank you