What is Long Covid?
HTML-код
- Опубликовано: 16 сен 2024
- Today we are talking about "What is #longcovid?"
Long Covid is typically defined as symptoms persisting for more than 3 months after a covid-19 infection. Unfortunately for many many sufferers, it's more than just a prolongation of their infection symptoms. It's the onset of various other symptoms such as extreme exhaustion, cardiovascular, neurological, dysautonomia-like, symptoms, amongst many others.
Check out the video to know more :)
I promise this is the longest video of the channel ;)
References with clickable links are coming soon! (I will have to make a youtube verification step)
[1a] WHO: who.canto.glob...
[1b] WHO delphi consensus: www.who.int/pu...
[1c] NHS: www.nhs.uk/con...
[1d] CDC: www.cdc.gov/co...
After mild infection
[2] Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study doi.org/10.101...
[3] Long COVID following mild SARS-CoV-2 infection: characteristic T cell alterations and response to antihistamines jim.bmj.com/co...
[4] Symptoms and risk factors for long COVID in non-hospitalized adults www.nature.com...
Neuro:
[5] Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients doi.org/10.101...
[6] Long-term neurologic outcomes of COVID-19 www.nature.com...
[7] COVCOG 2: Cognitive and Memory Deficits in Long COVID doi.org/10.338...
[8] Self-reported Memory Problems 8 Months After COVID-19 Infection jamanetwork.co...
[9] Ed-Yong's article: www.theatlanti...
Neurotransmitters:
[10] Boldrini et al. (2021) Neuroscience and Psychiatry. How Covid-19 affects the brain: jamanetwork.co...
Fatigue:
[11] Post-acute COVID-19 Syndrome Negatively Impacts Physical Function, Cognitive Function, Health-Related Quality of Life, and Participation www.ncbi.nlm.n...
[12] Wu et al 2022 Long COVID and symptom trajectory in a representative sample of Americans in the first year of the pandemic www.nature.com...
[13] Davis et al 2021 - Characterizing Long Covid: pubmed.ncbi.nl...
[14] Symptom Burden and Immune Dynamics 6 to 18 Months Following Mild Severe Acute Respiratory Syndrome Coronavirus 2 Infection (SARS-CoV-2): A Case-control Study academic.oup.c...
[15] Chronic Fatigue and Postexertional Malaise in People Living With Long COVID: An Observational Study academic.oup.c...
Exertion intolerance:
see 15
[16] Washington Post Long Covid exercise Symptoms: www.washington...
[17] Schwendinger et al. (2022) Sports Medicine. Low Cardiorespiratory Fitness Post-COVID-19: A Narrative Review: link.springer....
PESE:
see 13 and 15
[18] Long Covid physio:Post-exertional malaise: longcovid.phys...
Cardio:
[19] Long term cardio vascular outcomes: www.nature.com...
[20] Long-term cardiovascular outcomes in COVID-19 www.thelancet....
[21] Long-COVID postural tachycardia syndrome: an American Autonomic Society statement doi.org/10.100...
Dysautonomia:
[22] Clinical characterization of dysautonomia in long COVID-19 patients www.nature.com...
[23] Autonomic dysfunction in post-COVID patients with and without neurological symptoms link.springer....
Various:
see 1 and 4
[24] Persistence of somatic symptoms after COVID-19 in the Netherlands: an observational cohort study doi.org/10.101...
[25] Kidney outcomes in Long Covid jasn.asnjourna...
[26 - testosterone] Persistence, prevalence, and polymorphism of sequelae after COVID-19 in unvaccinated, young adults of the Swiss Armed Forces www.sciencedir...
Very refreshing to hear someone actually explain the neurological symptoms properly. The term "brain fog" is bandied about, but it doesn't even come close to the reality of that nightmarish experience
Dude, you explain this so well. I completely concur, especially with the description of neurological symptoms.
Thank you for the nice words :)
@@longcovidontheshort Thanks for this educational resources 🥰
Could it be that you have a Mastodon account? I'm migrating from Twitter.🙏
One thing I have struggled with when conveying the extent of fatigue I feel is that it is beyond any fatigue I have ever felt, even after having an appendectomy. So many people attribute it to just normal fatigue. It is not. Not even close. The subtext at around 6:30 stating about the body becoming a prison is such an accurate description of Long Covid as a whole.
I totally agree, most people have no idea that this fatigue is not being tired, it really is outside anything I had experienced before and it's not easy to convey to others.
Thank you for producing these videos. So far they are excellent. I wanted to add one very common symptom that you did not mention: tinnitus. I was infected a year ago and developed severe PESE (and tinnitus). Last June I started experimenting with some extreme fasting regimens and it helped me resolve most of my symptoms (fasting is something you might look into and cover in a future video). However, the one symptom that persists for me is tinnitus. It is loud and very annoying. All the best!
Yes tinnitus can also occur in Long-Covid. I for example had a very annoying tinnitus in the beginning which now has much subsided, but is still faintly there. There are many symptoms I could not cover due to time. Another which could potentially have made the cut is rashes and intolerances
you should do a segment on Long Covid and pregnancy. There are stats out that says population growth has declined substantially in the last couple years. This is the first time i have ever heard, that a population forced to stay indoors has stats like this.
Hello, and congratulations on your channel. Super great idea! I see you didn't mention one of the most frequently observed neurological symptoms: headaches. In several studies I've read, it's always one of the top three symptoms. In fact, I suffered long covid myself, and from the first eight symptoms I had through the first four months, nearly-daily headaches lasted for more than 18 months and still persist today! I'm just starting to feel some relief just recently... hope to find answers in your channel.
Question: are you interested in interviewing patients who have experienced long covid? And the numerous treatments they have tried? I'd love to see these types of interviews. Thanks for the information.
I have PESE problems. While I'm doing sports (running, cycling) everything is o.k. But next day I feel like shit. I would have headaches for days in row and GI problems - extremely bloated stomach to the point that I have difficulties breathing normally, and it get very bad if I then also eat some fermented food. It's driving me crazy. I used to feel great after sports. Not any more. And it's been going on for almost a year now...
Sorry to hear about that, it really sucks... Bloating like that could be a sign of dysautonomia by the way. I didn't understand if the GI problems would also come after exercise, but if so it could be that it's flaring up some degree of dysautonomia. I would just be careful to not push it too far. Stay strong, I also really miss doing sports
I have IBS and Long Covid has caused me to have issues to where I get so bloated that it is hard to breath as well. I really did not attribute it to Long Covid until recently. I honestly thought it was from being forced to be less active. My son just graduated from college and two days worth of activities related to that have me ill, and the bloating is here again. So yes, I too find that activity increases symptoms of issues I had previously.
3:20 - Interesting. I haven’t heard of this depletion of precursors of neurotransmitters hypothesis before. Which paper was that?
Hi! That would be reference 10 in the video description for a quick overview of the hypothetical mechanism