Metformin and Vitamin B12 Deficiency
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- Опубликовано: 7 фев 2025
- Jill Crandall, MD, Professor of Medicine at Albert Einstein College of Medicine in New York, shares insights about metformin and vitamin B12. Dr. Crandall discusses the findings on long-term metformin use and vitamin B12 deficiency in the Diabetes Prevention Program Outcomes Study (DPPOS) and shares her thoughts on what could be done clinically based on these results.
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I greatly appreciate your video, which delves into topics beyond what I've encountered on other platforms. Thank you sincerely.
I was considered pernicious anemia and had to do those b12 shots for a year total (started with daily, then weekly, then monthly shots). Then I switched to a sublingual tablet. I have better numbers with the sublingual than the shots but "your mileage may vary". I was told to take B12 for the rest of my life. I felt literally like I was dying when I had the PA and it was so horrific that I don't wish it on anyone... I was supposedly just a few clicks away from being so deficient that I would have had psychosis!
I like the sublinguals from Trader Joes. They are inexpensive, dissolve quickly and don't have a strange taste to them. Anyhow, even it it is only 9% of people who are on long term metformin as I was/am, it is serious for those who suffer. No one told me that this was a common side effect of metformin, or to look for symptoms to discuss w my doctors until it was almost too late. There needs to be much more awareness in the community.
i am diabetic, since 15 years i am taking metform medicine in one or other tablets, now i have developed B12 deficiency, as when i lie down and get up and suddenly i feel dizziness, ,i dont get taste in my food, i get tired very fast, while walking i feel as if i am unbalanced , but i always walk atleast 2 to 3 km daily , now i am taking Seven seas cod liv capsule 2 daily, and purchased methylcobalmin tab for 10 tab, rs 110, and purchased Neurobin tab and taking both tab 2 ,. 2 daily for few days, now i feeling something better within taking these three medicine, now i want to control my sugar tablet daily only two times,
i feel i can regularise my B12 label in my body
I just started Metphorman and added "Methyl B-12 2500 Mcg to my diet.
I have been taking Metformin about 11 years ...my B-12 got low ...went on time released B-12 and I had good results...I am normal again.
Finally answered my question. But when will we know if b12 supplements work in preventing the b12 deficency? Are there any trials going on?
For general information on vitamin B12, please visit the NIH's Office of Dietary Supplements webpage at ods.od.nih.gov/factsheets/VitaminB12-Consumer/. Additionally, the website www.Clinicaltrials.gov is a registry of federally and privately funded research studies in the United States and around the world. It has information about a trial’s purpose, who may participate, locations, and who to contact for more details. You can view a filtered list of clinical studies on vitamin B12 deficiency at: clinicaltrials.gov/ct2/results?cond=B12+Deficiency+Vitamin&Search=Apply&recrs=b&recrs=a&age_v=&gndr=&type=&rslt. You can expand or narrow the list to include clinical studies from industry, universities, and individuals; however, the NIH does not review these studies and cannot ensure they are safe. Always talk with your health care provider before you participate in a clinical study. You can also learn more about clinical trials, including how to find a clinical trial, on the NIH website: www.nih.gov/health-information/nih-clinical-research-trials-you.
I have been taking Metformin for about 4 years now and just found out I’m B-12 deficient. Doctor wants me to have one shot a month for 6 months and then she will retest. I’ll probably have to take supplements the rest of my life. Been feeling dizzy, have restless leg syndrome, and food tastes different.
Wait, why would you have to take b12 supplements all your life?
Metformin constantly gives me diarrhea 4-5 times a week. I lost 55 pounds in 2 years and 6 months without dieting. From 205 lbs to 150 lbs.
I'm glad I lost weight, but it's scary to lose weight without wanting to.
The doctor ended up replacing the metformin.
What you taking now?
@@blanc00x
The doctor said my diabetes was mild.
The doctor replaced the metformin with sitagliptinme formin. My sugar level has not increased and I no longer have diarrhea. My weight hasn't changed, and I still weigh 150 lbs.
So everything is fine now.
My specialist is treating me for my blood work high white blood cell count said I didn’t need B-12 because my food gives it to me but I really wanted the B-12 shot because I never know if I will eat good with my swallowing problems
I started metformin 3 days ago to lose weight. (I am 5"4 and weigh 159 and want to get to my pre menopause weight of 129) I already dropped 3 lbs in 3 days. 500 mg.
I am taking nutritional yeast and taking 3000 mg of B12.
I don't have diabetes but my sugar cravings were horrible. I got the subscription online because my doctor would not give me one. My BMI was 28.
Where did you buy metformin?
@@sandravarkojyte2065 Ageless RX online
The problem is that if you listen carefully often you will hear "More studies need to be made" which tells you that they are not interested in the results because they may not like them and the pill industry will come down.
Most of the studies are funded by pharma companies and your are 100% correct , No pharma company would like that the Metformin industry to go down
Should i take the b12 with metformin at the same time or wait a while after taking the metformin. I be tired / fatigue a lot after taking metformin i bought some b12 pills they help but i wonder if a better time to take them before or after the metformin?
Unfortunately, we cannot offer medical or dietary advice and encourage patients to speak directly to a health care professional who knows their history and who will be the best person to provide specific advice. For general information on diabetes diet, eating, and physical activity, including dietary supplements, visit our website at: www.niddk.nih.gov/health-information/diabetes/overview/diet-eating-physical-activity.
For additional information on Vitamin B12, including recommended daily amounts, visit the National Institutes of Health's Office of Dietary Supplements website at: ods.od.nih.gov/factsheets/VitaminB12-Consumer/.
Watch the video…open a dictionary. Understand the video, it’s an absorption problem. As long as metformin is present it doesn’t allow absorption of b12. So if you were to take b12 supplements when no metformin was present it would do the trick.
Vegan for over 25 years when I was diagnosed as Diabetic and given Metformin little did I realise I would end up on quarterly B12 injections and meds for my stomach and top up Iron when my levels tank. At first it was suggested that it was my diet that caused the B12 problem, I pointed out it had never been a problem for 15 years before Metformin came along, I have managed to half my metformin dose and hope to eventually come off the rest but I still don't know if the damaged caused to my gut is permanent. I have been told I will need the B12 shots for the rest of my life...
😂😂😂
I wish doctors would taste this seriously.
And they dont
I had difficiency ,it is 112 pg /cl after 2 month medication,but now some of symptoms still not going
Should a supplement be needed when on a HFLC diet
For general information on dietary supplements, please visit the NIH's Office of Dietary Supplements website at ods.od.nih.gov/.
Unfortunately, we cannot offer medical advice or opinions and encourage you to speak directly to a health care professional who knows your history and who will be the best person to provide you with specific advice.
can i take 500 mcg once a week ? to keep healthy b12 levels , Now you can get only 500 or 1000 mcg on the market, what do you thinnk ?
Unfortunately, we cannot offer medical or dietary advice and encourage patients to speak directly to a health care professional who knows their history and who will be the best person to provide specific advice. For general information on diabetes diet, eating, and physical activity, including dietary supplements, visit our website at: www.niddk.nih.gov/health-information/diabetes/overview/diet-eating-physical-activity.
For additional information on Vitamin B12, including recommended daily amounts, visit the National Institutes of Health's Office of Dietary Supplements website at: ods.od.nih.gov/factsheets/VitaminB12-Consumer/.
Alright, the experts don’t know what the drugs are doing and what to do, but they will prescribe you drugs. Whatever.
You don't know what you are talking about.
@@Fomites Says the guy who himself doesn't know what either of them is talking about
They know
@@ynmamflm how do you know they know? because they told you as they get kick back from drug companies?
@@Fomitesmate, telling idiots they don’t know what they are talking about is like banging one’s head against a wall.
use sublingual. Goes right into the bloodstream.
Exactly. I’m still confused if any in a multivitamin absorbs.
Metformin induces cellular autophagy. That may be why absorption of B12 is either impaired or perhaps depleted within cells.
how do you know this?
Now I’m down 17 lbs in 40 days with Metformin I am a new woman
Does Metformin over many years have the same effct as proton pump inhibitors ?
Take sublingual (under tongue) lozenges
5 ft 10 178 lbs blood pressure ok
65 time to get to work sawadee khap