I reckon...all of this plus much more (Everything) is revealed to us after our "Death"...so I'm sorry to say you could be wasting your Life Time (plus all the other costs to everyone else) with all of this searching for "Immortality"...Disclaimer: This is just a "Food-For-Thought" rant...feel free to ignore it
Glad to see Rose hosting an episode again! It's pretty funny that when lasers were first developed they were criticized as "a solution looking for a problem". Now we've figured out ways to use them to tweeze apart DNA, cool atoms to tens of microkelvins, send large quantities of data over optical fibers, and all sorts of other amazing things. In a way, that saying was true, but lasers just happen to be a solution for so many things we keep finding new problems for them to solve 😁
@@MarkWTK ooh yeah that's another great example! It's amazing people have managed to not only figure out but then build a machine that can hit a droplet of molten tin with a laser once to turn it into plasma then a second time to generate a powerful EUV source. For anyone that would like to learn more about these crazy machines, Wired has a great piece titled "The $150 Million Machine Keeping Moore’s Law Alive".
Wait, I'm supposed to use *_tweezers_* to fix my glasses!?!?!? Why haven't I heard about this sooner, I'm almost 26, and it's much easier than those mini-screwdrivers... Also cool to learn about how a tweezer like mechanism can be used to untangle DNA that's pretty cool too.
DId you just describe what could be the beginnings of a TRACTOR BEAM!? I wasn't the only one that heard that a laser can pull rather than push......tractor beams! =)
Rose's videos are always a joy to watch. She's clear and understandable, at a great pace in her diction. She's also cute and fun to watch, making all her videos very enjoyable. She also has an added benefit of a fun last name, that alone says a lot about her background. You can't help but look her accomplishments up online and just drop your jaw at the amazing person she is. Thank you for your contributions.
First they take the dinglebop, then smooth it out with a bunch of shleem. The shleem is then repurposed for later batches.They take the dinglebop and push it through the grumbo. Where the fleeb is then rubbed against it. Its important that the fleeb is rubbed, because the fleeb has all the fleeb juice. Then a shlammie shows up and he rubs it and spits on it. They cut the fleeb. There are several hizzards in the way. The blamfs run against the trumbles and the ploobis and grumbo are shaved away. That leaves you with a regular old plumbus
DNA is such an incredible thing. I'm excited for the future where we can use DNA for data storage. Surprisingly stable if you keep it in optimal conditions and exceptional data density. Reading it quickly, mitigating data loss, and keeping it stable are some of the main issues with it, but even if the storage devices using it are huge and slow, they would be perfect for storage of data where you don't need instant access.
I love SciShow, but I’ve noticed they’ve been getting less than average views per video. I think the cause of this is because they don’t make jokes like Hank used to anymore. It mixed learning with laughter and that is the best combination for education in my opinion.
I don't know who edited this and had fun but, at 3:29 there's a sound like doing a pop with your mouth. I'm listening to this on 2x, and caught it, how did you guys miss it?
I have a DNA-related question: Can CRISPR be used to insert missing proteins into DNA? I recently found out that I'm missing two proteins in my DNA and I'm wondering if that's at all possible. My oncologist said that missing one protein is rare enough, but to be missing two proteins is, apparently, completely unheard of. Based on that, I'm guessing that there's not a lot of research being done on this.
The issue is you don't just have one copy of your genome to edit. You'd need to edit the genome in nearly every cell. Or at least all the cells in the primarily affected organ. Because all your cells have their own copy of the genome and all their copies are missing those two genes.
I guess you mean missing genes. Such a measure already exists - it's called gene therapy. However, I don't know if any of the gene therapy is based on CRISPR.
@@vitalyl1327 CRISPR has been modified to allow insertion too. Theoretically you can add back the genes or the right genes but not on an organismal scale, too many cells
@@carlodesa198 Yes, true, there are pathways allowing insertion after clipping. There were also CRISPR-guided integrase methods, which so far appear to be more precise. Can be wrong though, did not pay attention to the recent development.
So the whole point of this video as the title suggests is to explain optical tweezers and how it can pull dna strands yet they completely glossed over how the laser they use can pull. They just chalk it up to “a little quantum mechanical know how”.
Am I the only one bothered by the 'up-close' graphics of DNA that don't reflect the actual structure? It just looks like a rough-surfaced ladder, but if you render it accurately at that size, you should be able to see nucleotides/atoms. It's also not even a double-helix -- just a spiral.
Creo que la vibracion molecular con sonido y estados ocultos de la materia podría ayudar, si el sonido levita agua podría hacerlo con células y adn, donde las vibraciones se aciplen para transformar y manipular el genoma humano creo sugerencia.
Uhm, excuse me, WTF? Not only there's something called *optical tweezers*, but it's possible to use a laser to *pull* on stuff????? Holy crap, science never ceases to amaze me
Try again? Your comment is so unintelligable, it's like it was translated from an ancient alien language by google translate. And no, the majority of the X chromosome is not silenced. At least across the entire human population, because it's a) not silenced at all in chromosomal men, because that would be lethal and b) only one of the two copies in chromosomal women is silenced for dose compensation. So, the overwhealming majority of X chromosomes on this planet is not silenced. But why does it surprise you that most of our genes are usually switched off? I don't think you need your HOX genes anymore after your born, because there's no new limbs that need defining new buds. So, of course they're switched oft, because otherwise they would wreak havoc?
@@midnight8341 to Be any particular species 90% of genome is silenced. Much each chromosome including the X is slinced and get this the most active X is the paternal
Go to Brilliant.org/SciShow to try their Waves and Light course. Sign up now and get 20% off an annual Premium subscription.
I reckon...all of this plus much more (Everything) is revealed to us after our "Death"...so I'm sorry to say you could be wasting your Life Time (plus all the other costs to everyone else) with all of this searching for "Immortality"...Disclaimer: This is just a "Food-For-Thought" rant...feel free to ignore it
Glad to see Rose hosting an episode again! It's pretty funny that when lasers were first developed they were criticized as "a solution looking for a problem". Now we've figured out ways to use them to tweeze apart DNA, cool atoms to tens of microkelvins, send large quantities of data over optical fibers, and all sorts of other amazing things. In a way, that saying was true, but lasers just happen to be a solution for so many things we keep finding new problems for them to solve 😁
and also EUV machines too, those are next level tech! amazing
@@MarkWTK ooh yeah that's another great example! It's amazing people have managed to not only figure out but then build a machine that can hit a droplet of molten tin with a laser once to turn it into plasma then a second time to generate a powerful EUV source.
For anyone that would like to learn more about these crazy machines, Wired has a great piece titled "The $150 Million Machine Keeping Moore’s Law Alive".
And it's all just light waves in the end so crazy
I turned this on to have something to listen to while I crochet. The tension, twisting, and thread metaphors are all hitting for me.
You never know what you'll learn on this channel, thanks for all the great videos!
I actually liked the under-lighting in this episode. It felt very soothing and calming.
Yes! And now I'm going to go looking for her earrings. They are gorgeous. But also I was very interested in the optical tweezers. ;)
@@DianeKovacs they’re hand beaded earrings! They’re probably one of a kind
@@Nata-rb4vc Yes. But I'll bet if I can find the artist I might get something similar. But I'll be good. :)
Something about the clarity of Rose Bear Don't Walk's voice and her overall charisma enable her to very effectively convey complex information.
This episode looks awesome! I love the way it's lit and edited!
I feel like this should be making primetime news, just a 5-10 min portion that discusses scientific progress like this
Good to see you again, Rose Bear Don't Walk.
Wait, I'm supposed to use *_tweezers_* to fix my glasses!?!?!?
Why haven't I heard about this sooner, I'm almost 26, and it's much easier than those mini-screwdrivers...
Also cool to learn about how a tweezer like mechanism can be used to untangle DNA that's pretty cool too.
No, you're supposed to tighten those screws with a mini laser induced repulsor beam.
@@tomf3150 Haha got it, my mistake
I thought the lasers were for the yoyos
Is this a new editing style? I really like how fluid and dynamic the video is. Just wanted to verbalise that for you to see.
DId you just describe what could be the beginnings of a TRACTOR BEAM!? I wasn't the only one that heard that a laser can pull rather than push......tractor beams! =)
My thought exactly! Mind you it probably doesn't work above nanoscale but DAMN THAT'S COOL
@@akhragee Perhaps if you use billions of these lasers at once on billions of different atoms
We can have tractor beam fight :v
@@akhragee It's gotta start somewhere =)
@@khaucan5068 haha soon, I hope
"Use a laser beam to gently pull"
So wait when did we invent tractor beams?
This video made me realize that Yoyo is one funny sounding word for sure! Haha! 😄
Rose's videos are always a joy to watch. She's clear and understandable, at a great pace in her diction. She's also cute and fun to watch, making all her videos very enjoyable. She also has an added benefit of a fun last name, that alone says a lot about her background. You can't help but look her accomplishments up online and just drop your jaw at the amazing person she is. Thank you for your contributions.
First they take the dinglebop, then smooth it out with a bunch of shleem. The shleem is then repurposed for later batches.They take the dinglebop and push it through the grumbo. Where the fleeb is then rubbed against it. Its important that the fleeb is rubbed, because the fleeb has all the fleeb juice. Then a shlammie shows up and he rubs it and spits on it. They cut the fleeb. There are several hizzards in the way. The blamfs run against the trumbles and the ploobis and grumbo are shaved away. That leaves you with a regular old plumbus
F A X
5
As a lover of miniatures & science, the title 100% delighted me!!
Yeah man I definitely understood this entire video completely
very well explained and presented
So
Scientists invented what's essentially a microscopic quantum tractor beam
DNA is such an incredible thing. I'm excited for the future where we can use DNA for data storage. Surprisingly stable if you keep it in optimal conditions and exceptional data density. Reading it quickly, mitigating data loss, and keeping it stable are some of the main issues with it, but even if the storage devices using it are huge and slow, they would be perfect for storage of data where you don't need instant access.
And I thought untangling the Christmas lights was hard.
I love SciShow, but I’ve noticed they’ve been getting less than average views per video. I think the cause of this is because they don’t make jokes like Hank used to anymore. It mixed learning with laughter and that is the best combination for education in my opinion.
Yay, Robert Amling for sponsoring the c. 2:28 video image!
Very interesting episode!
Fascinating info and excellently explained by Rose 🙌 💕
You're awesome, Rose!
I wish EVERYONE would put the sponsors at the end of the video like that that's perfect
Those frickin' lasers at it again... :P
dude...........that lighting makes her look so 3D it's like I changed the options on my pc..
I recognize that voice! Welcome back Rose Bear Don't Walk! Where have you been?
Tell me optical tweezers aren’t just a miniature tractor beam
4:35 Same.
I don't know who edited this and had fun but, at 3:29 there's a sound like doing a pop with your mouth. I'm listening to this on 2x, and caught it, how did you guys miss it?
I have a DNA-related question:
Can CRISPR be used to insert missing proteins into DNA?
I recently found out that I'm missing two proteins in my DNA and I'm wondering if that's at all possible.
My oncologist said that missing one protein is rare enough, but to be missing two proteins is, apparently, completely unheard of. Based on that, I'm guessing that there's not a lot of research being done on this.
The issue is you don't just have one copy of your genome to edit. You'd need to edit the genome in nearly every cell. Or at least all the cells in the primarily affected organ. Because all your cells have their own copy of the genome and all their copies are missing those two genes.
I guess you mean missing genes. Such a measure already exists - it's called gene therapy. However, I don't know if any of the gene therapy is based on CRISPR.
CRISPR can be used to remove sequences. To add something you need an integrase (similar to the one used by HIV).
@@vitalyl1327 CRISPR has been modified to allow insertion too. Theoretically you can add back the genes or the right genes but not on an organismal scale, too many cells
@@carlodesa198 Yes, true, there are pathways allowing insertion after clipping. There were also CRISPR-guided integrase methods, which so far appear to be more precise. Can be wrong though, did not pay attention to the recent development.
So the whole point of this video as the title suggests is to explain optical tweezers and how it can pull dna strands yet they completely glossed over how the laser they use can pull. They just chalk it up to “a little quantum mechanical know how”.
Ah Yes, retractor beams... ofc there are retractor beams...
Mind = boggled!
I can hear Rose’s voice echoing of the walls of the studio. Not that annoying, but noticable)
Could you please fix it?
Use tweezers to tighten up screws in your glasses??!! Don't bother with a screwdriver... For screws in your glasses you use a hummer. 😂
The vocab in this video felt like a Dr Suess book
I thought they discovered a way to make literal tiny tweezes
Y'all had to drop this the day after my biochem exam that had tweezers on it
The worlds smallest tweezers tell us that even DNA has more girth than you
The More You Know ;)
Wow
so... tractor beam?
Oooooo she's still going after the move 🤌👏💪
3:21 we are 1 step closer to tractor beams.
Nice to know we have mini tractor beams already.
So, these are the tweezers CRISPR gene editing uses?
It's a freaking tractor beam. Cool!
I saw cartoons and drawings, but no actual film or photos of the DNA being separated. Is there a video showing this?
Am I the only one bothered by the 'up-close' graphics of DNA that don't reflect the actual structure? It just looks like a rough-surfaced ladder, but if you render it accurately at that size, you should be able to see nucleotides/atoms. It's also not even a double-helix -- just a spiral.
TRACKTOR BEEEEEEEEEM!!!!! :O
Jesus how does scishow get such pretty hosts who are also so intelligent.
Lasers that can pull… so this is how aliens abduct cows.
The power of science! The power of evolution! The power of genetics! 💕 ☮ 🌎 🌌
Hey, look who it is...😃
Rose is wonderful but I have no idea what I just listened to I couldn't focus on the words with the continuous change in inflection.
Oddly enough, that's what keeps me interested.
I've got to quit cuz she's my favorite speaker I don't want her going anywhere
Just as always:
What can we do to solve this pr- "LASERS!"
Neat
Is something like this usable for Lazer Eye Surgery?
Day 120 of asking for the return of Scishow Quizshow
Tractor beam confirmed !
Dope
Wait? The first laser was invented in Malibu?! I need more information, please...
I am more confused now than ever. Where is all of this heading to?
I recently heard about optical tweezers from an article about 2D supersolids. Cool!
Can you make a video of animals with ancestors that are still alive like butterfly evolving from moths
SciShow: People use tweezers to pluck eyebrow hair.
Also ScShow: Lasers can be used as tweezers.
Me: *Shines laser in eye.
Laser hair removal is a thing...
how does a laser pull. I call bs
I never know WHEN the pun will come, just that it will
WHAT IS THIS?! TWEEZERS FOR ANTS?!?!
Creo que la vibracion molecular con sonido y estados ocultos de la materia podría ayudar, si el sonido levita agua podría hacerlo con células y adn, donde las vibraciones se aciplen para transformar y manipular el genoma humano creo sugerencia.
It looked and sounded like it was shot in a dungeon.
Ever since Rose found her flow she’s become my favorite host
Absolutely
Right behind hank of course
@@curiodyssey3867 I see Hank as more of a principal than a teacher
Histone proteins 2m DNA fit into just som microns
Do i need these to build the world's smallest computer?
I would like to play with yo-yo right now. Don't know why, the video was definitely not about yo-yos
Never used a tweezer in my life lol
Something’s wrong with the lighting but I can’t tell what
Next headline: we found micro (or whatever size it would have to be to exist in our DNA lol) plastic in our DNA, what now?
I came for the “D” jokes.
Uhm, excuse me, WTF? Not only there's something called *optical tweezers*, but it's possible to use a laser to *pull* on stuff????? Holy crap, science never ceases to amaze me
A comment to appease our algorithmic overlords
The title….
I’m fairly certain dna is god
Its a shame you can't use tweezers on acne.
She talks at the perfect rate.
Google owns our DNA too?
How can something so small be 98 ft long?
Humans be humans *poke* *squeeze* *stretch* things 😁
everyone is talking about the new video style, and although i like it....i hear an awful echoing. i can't be the only one who hears that, right?
That stood out this was definitely shot in a different studio to the usul one.
"At the end you're left with a pile of yo-yos".. are we still talking about DNA, or the election cycle? *rimshot*
Vast majority The X chromosome . Or about all chromosomes are. Silenced I don't if The why or smaller chromosomes have most active genes
Do you want to try writing your comment again? It doesn't make sense.
Try again? Your comment is so unintelligable, it's like it was translated from an ancient alien language by google translate.
And no, the majority of the X chromosome is not silenced. At least across the entire human population, because it's a) not silenced at all in chromosomal men, because that would be lethal and b) only one of the two copies in chromosomal women is silenced for dose compensation. So, the overwhealming majority of X chromosomes on this planet is not silenced.
But why does it surprise you that most of our genes are usually switched off? I don't think you need your HOX genes anymore after your born, because there's no new limbs that need defining new buds. So, of course they're switched oft, because otherwise they would wreak havoc?
@@midnight8341 to Be any particular species 90% of genome is silenced. Much each chromosome including the X is slinced and get this the most active X is the paternal
@@minnymouse4753 Am I right in guessing English is not your first language?
Be vegitarian be healthy be happy save innocent animals from being slaughter
im happy and healthy regardless.
@@spatrk6634 then let other innocent animals live the only life they get ❤️
@@davidkumarmaxi6843 they got their lives in the first place just to be food.
farm animals wouldnt exist without humans
Narrative of Self is the result of a feedback loop between “Separate Self” & Cosmos 🎈
Is sci-show just going to gloss over the fact tractor beams have technically already been invented?