Mechanism of action of Spironolactone
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- Опубликовано: 17 сен 2024
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Video Summary:
This video describes mechanism of action of spironolactone. It's an aldosterone antagonist. Aldosterone regulates Na reabsorption by principle cells at collecting duct. It increases synthesis as well as activity of Na-K ATPase pump and epithelial Na channels which plays important role in Na reabsorption at collecting duct. Due their increased activity Na reabsorption is increased. Increased Na reabsorption indirectly increases K excretion. Spironolactone inhibits mineralocorticoid receptors through which aldosterone exerts it's effect. So all the effects of aldosterone is decreased. Na is lost in urine and K is prevent from excretion.
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DISCLAIMER: This video is for education purpose only. Although every effort is made to ensure accuracy of material, viewer should refer to the appropriate regulatory body/authorised websites, guidelines and other suitable sources of information as deemed relevant and applicable. In view of possibility of human error or changes in medical science, any person or organization involved in preparation of this work accepts no responsibility for any errors or omissions or results obtained from use of information in this video.
Please keep making videos, they are really helpful, thank you so much
Yes I am uploading videos regularly. Stay tuned😊
Wow.I am amazed by the simplicity and effectiveness of this short video❤.
I've spent a lot of time trying to find this information! thank you so much!
Really Helpful 👍
Thank you ❤
One word…….BEST.
Thank you so much for this, it made the concept perfect....
great video! thanks from the UK
Welcome 😊
Great video & energy! ✨ Thank you!
U r great and your work is ossm
Thank you..
Awesome explanation
Glad you liked it. Please keep sharing.!
@@NonstopNeuron sure sir
Which are most preferable diuretic?
Depends on disease. For chronic use like hypertension, thiazides are preferred. For emergency need loop diuretics are preferred.
@@NonstopNeuron ty so much sir
You da real MVP
Minimum Viable Product?
Thank you soo much
Thank you sir very helpful
Most welcome 😊
Great job
Excellent!!!
Thank you
Very good, thank you
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Well explained
Very nice explanation ☺️
Keep making such videos 😇
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Thanks alot sir...u r doing a great job sir...keep going on...
Always welcome
Thank you 🙏🏼
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thank you!
thanks
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Thank you, I will. Please keep sharing😊
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Well explained in just less than 3 minutes 👌🏻👌🏻👌🏻👌🏻👌🏻
I appreciate sir, you made it so easy for us. I have a question. why Spironolactone can be used for acne?
Principal cell*
Sir plz upload drug used for shock
Hi Silpa, thanks for visiting the channel and requesting a topic. I am following a specific plan so this topic wont be possible any time soon. However I have noted down your request. Thank you 😊
Thanks for your reply..
Your videos are very useful and it made pharmacology easy...
Keep going..🤝 expect more more topics😊
Thank you very much. Yes I am uploading as many videos as I can😊
Just been put on this drug
🔥☠️🥲🤞☠️🔥😹💯💯
ok but i did not understand one thing sorry
Thanks
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