All About Reductive Amination

joechem.io/vid... for video on jOeCHEM and attached worksheet + solution (below video on jOeCHEM aka the link).
Worksheet: worksheets.joec...
Worksheet Solution: worksheets.joec...
Worksheet Solution Walkthrough video: joechem.io/vid...
Study Guide: N/a (Joe's working on it!)
In this video, we take a look at Reductive Amination--its mechanism and how to predict products successfully. What's awesome is, if you put in the work back when we worked with imines (joechem.io/vid...) this will be very familiar and a cakewalk for you.
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[@user8_8]

Very helpful explanation, thank you so much!!

[@shoutitallloud]

You look too young for mr.Heisenberg... But anyway, here's your phenyl-propan-2-one.

[@NikOthman]

👍👍👍Next pls how to synthesis 1phenyl2propanone?? Thank you

[@doaamahmoud7114]

Thanks that was so much helpful!!!

[@Piocoto123]

Thank you for the video! Do you know what does the boron ends up turning into? some borate?

[@kobold7763]

So would this reaction work for reductive animation of n,n diethylamine to n,n Diethylmethylamine?

[@ajx8571]

This is awesome bro thank you.

[@skriosorgooeltkhgo4068]

Can't you use LAH if you extract and purify the imine instead of doing a one pot reaction?

[@directionerhere932]

how to do this mechanism if we're doing it in neutral condition. Amine directly attacks the aldehyde, but the double bond of the carbonyl wont shift right?

[@erikdejong4509]

When you add your NaCNBH3 do you still need to add acid to protonate the N or is there still H3O in your solution

[@spurti]

Hii I have a question can we produce 1° aromatic amines from gabriel pthalimide synthesis???like aniline for example.

[@krish1596]

Can we use H2, raney Ni? Instead of nabh3cn?

[@jOeCHEM]

In theory, that would perform a reduction, but I have personally never seen something used in place of nabh3cn for this reaction. So I would say stick with nabh3cn unless your instructor uses something different.

[@jhyland87]

well done. subscribed

[@ghadasalah1937]

thankkkkkkkkkkkkk uuuuu

[@jOeCHEM]

yourrrrrrrrrrrrr welcomeeeee (thanks for watching!)