Superiority, non-inferiority and equivalence trials

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  • Опубликовано: 21 окт 2024

Комментарии • 6

  • @rheajoseph6506
    @rheajoseph6506 4 года назад +2

    well explained! how is this connected to power calculations? can you please explain this:
    "The power calculations were originally performed for a non-inferiority study concept assuming 70% effectiveness for CBT and 85% for TFT, with 80% strength and 10% CI and an accepted 10% delta, yielding 34 patients in each therapy group. As both the criteria for estimating effectiveness for TFT, and the non-inferiority margin for scores on the ADIS avoidance scale are highly uncertain, we present our findings as a conventional superiority trial with two-sided statistical tests."

    • @dranantpharmacology
      @dranantpharmacology  Год назад

      For this study, authors originally did power calculation for non-inferiority study but later design was changed to superiority study.
      Whatever is the study design (superiority, non-inferiority or equivalence), power calculation is necessary. Usually power is considered 80%.
      I hope, I could explain your question.
      Sorry for delay in answering.

  • @trance108
    @trance108 Год назад

    Keep going sir 💪

  • @rajeshmailagire
    @rajeshmailagire Год назад

    Nice sir, thanku so much 👍

  • @rajeshmailagire
    @rajeshmailagire Год назад +1

    👍👍👍👍👍🙏

  • @utubetipico8735
    @utubetipico8735 6 месяцев назад

    terrible audio