I just caught this lecture on UCTV this evening, and came to youtube so I could post and share on facebook. Several people close to me have had or are dealing with cancer right now, and I want to thank you for this clear, calm, concise lecture. -Jean
I find this very very useful, i live in sweden and i rather listen to ppl teaching in english about biology, than listening to an swedish teacher talking about biology. Im fourteen, and i love biology. Great vid btw.
@ojeano So glad you found this talk useful. Thank you for sharing. This month we are featuring a series of talks from @UCSF about "Winning the War on Cancer in the 21st Century" on our website as well. All the best to you and your family. -UCTV
@rodeo179 Have you seen our "Med Ed" programs on our website? We have hundreds of videos from UC medical schools aimed at health care professionals, some with CME credit. You can find them at uctv dot tv slash meded. A playlist is coming soon too!
Cancer is the body's inability to stop the process of healing, the same natural process in producing a placenta (that one pound organ attached to the uterine membrane which serves to nourish a developing baby). The essential anti-cancer vitamin is VITAMIN B17 (known as Amygdalin, and as Laetrile when synthesized from apricot pips).
Idk if Im stupid and been wrong for so many years, but at 10:00 she claims the first 4 are considered benign, and the last one is malignant. To my understanding, carcinoma in situ is already considered malignant. In neoplasic events, those referring to epithelial tissue are usually called Adenoma, when benign; and Carcinoma, when malignant. The 'in situ' portion of the diagnosis does indeed mean it hasnt invaded other tissues, but thats just considered a premetastasic phase, doesnt mean its not "planning to". As for your answer, a physician will initiate therapy so long as 1) There is verified malignancy 2) There is chance for malignancy but the treatment is simple (like polips) 3) Future malignancy is possibility and treatment is not too invasive. Thats more or less a very general rule on how physicians decide. If they were to wait till its invasive, itd be like saying "Yeah, Im not treating you until youre very likely going to die".
Things to take into account: 1) When referring to probability of malignancy to determine whether or not a physician will treat it, the probability has to be significant, there are lots of statistics involved (mostly money related) that will help a physician determine whether or not its worth treating someone or not. 2) I realize, in my comment, there are a few grammatical and syntax errors, sorry.
I heard from Aathony Robbins that there was a study where people kept chicken cells alive by removing the waste and keep the oxygen as necessary and when they lowered the oxygen and let the cell be in its own waste then the cell turned cancer. Does this have any truth.
Alan C. Nixon Ph.D., past president of the American Chemical Society writes, "As a chemist trained to interpret data, it is incomprehensible to me that physicians can ignore the clear evidence that chemotherapy does much, much more harm than good."
“No chronic or metabolic disease has ever found cure or prevention, that is, real cure and real prevention--except through factors essential to an adequate diet and/or normal to animal economy.” -- Dr. Ernst Krebs, Jr.
Although I think there are several very good alternative treatment options available for treating cancer today, including cannabis oil...we can never have enough good information, so good job.
I just love doctors who talk about health " that are by far are not healthy by any means ! And I'm going to trust you ? Ketoginic life style will help your cells !!!! Been around since 1800s ! Better than cut " poison " burn !!! Do no harm ???
Success of most chemo-therapies is appalling…There is no scientific evidence for its ability to extend in any appreciable way the lives of patients suffering from the most common organic cancer… Chemotherapy for malignancies too advanced for surgery, which accounts for 80% of all cancers, is a scientific wasteland. [Dr. Uhlrich Abel, "Chemotherapy of Advanced Epithelial Cancer," Stuttgart, 1990]
I am sorry about this long comment, but she does not sound or look like she knows anything about nutrition, or the role it plays in cancer. It is all about procedures and medications because that's where the $$$$ is. The stuff sold as human food are products of the evolution of food commodities that maximize profit margins. There are powerful forces that benefit from making people sick! This is not a conspiracy theory, but a fact about the way food items are produced. “Health” industries have benefited from “sick” people; and their profit margins are directly dependent on the consumption of stuff sold as human food. They have influenced the very institutions that are supposed to help people see the truth, to the point that a good number of these institutions have become complicit in profiting from people’s suffering. People are addicted to the stuff they are fed by the food industries! Food addiction is much harder to grapple with than any other chemical addiction! I like the comparison Dr. Greger (from nutritionfacts.org) makes with the cigarette addiction; he notes that what we are dealing with today with food addiction is similar to the time when many, including the majority of doctors and scientists, were addicted to cigarettes. People need to first face the fact that they are addicted to the “food” that is making them sick, and then try to deal with it. But it is hard for people to break their denial of their own food addiction. What about cance? Cancer is typically considered to develop in a sequence of three stages: initiation, promotion, and progression. Dr. T. Colin Campbell's Cancer Research has resulted in an understanding of the role genes, chemicals, and nutrition play in cancer development in all three stages. The specific effects of the amount and type of protein consumed have been studied. Others in the scientific community have overemphasized the role of chemical carcinogens, which are mainly initiators of cancer; they have under-emphasized nutrient imbalances (such as the amount and type of protein consumed) as causes of cancer. But animal protein has shown to play an important role in development of cancer in all three stages of cancer. Specifically, the role protein plays in the promotion stage has been studied extensively. In the initiation stage carcinogens (in foods, added to foods, or in the environment) are absorbed and then enzymatically converted to products that are excreted from the body. The small amount of the chemicals is converted to a highly reactive product that converts normal genes to cancer genes. Most of the damaged DNAs are repaired by the body; if cells containing the damaged DNA do not get repaired and allowed to divide into new cells, then the mutations become fixated in the future cell generations. The damaged (un-repaired) cells continue to multiply through the promotion stage, and begin to form clusters (foci) which may be seen microscopically. These foci gradually grow into active tumors, and are diagnosed eventually as cancer. Tumors may metastasize, leave and invade neighboring or distant tissues. These cancerous cells become malignant, which means they become relatively independent, aggressive, and resistant to their destruction. The role of protein Dr. Campbell’s team in Philippines (1970s) observed that children who consumed higher protein diets were the ones with higher rate of liver cancer. This was an early indication of the possible relationship between cancer and consumption of protein. His experimental research has later experimentally measured early lesions (called GGT-positive foci) that would lead to tumors. These GGT foci are considered early events in carcinogenic processes. Protein feeding in rats with viral cancers caused by Aflatoxin and hepatitis B virus showed an increase in early tumor development. The 20% protein diet turned GGT foci development, but 5% protein diet turned off the GGT foci development. They also discovered experimentally that animals fed 20% protein diet had lots of tumors and all died by 100 weeks, and the ones fed 5% protein diet were energetic and well at 100 weeks. This was true for viral and chemical induced cancers. Dr. Campbell’s research has shown that high protein affects cancer development during both the initiation and promotion stages. They found explanatory mechanisms that were caused by high protein diet. Throughout the studies they used casein (cow’s milk protein), and observed that soy and wheat proteins did not have the same effect at 20% protein diet. The dose response relationship started at levels above 10%. The 20% protein diet also caused an increase in the liver MFO enzyme activity in the initiation stage. MFO is the principle enzyme responsible for metabolizing carcinogens. In addition to the effects high protein diet showed in the initiation and promotion stages, it was shown that small shifts in percentage of protein diet can turn cancer on and off even at relatively advanced stages of disease! In studies of effects of carcinogens on animals the amounts used are several orders of magnitude higher than in the human studies. This causes the need for extrapolation from animal studies to human studies. But, in the case of casein, the amount of casein humans consume is at the same order of magnitude as in animal studies. This, according to Dr. Campbell, makes casein the most significant carcinogen ever discovered! Others in the scientific community have ignored the one carcinogen that has been shown to cause cancer at the levels that don’t require extrapolation to low level exposure in humans, and have made a huge deal about the ones that are not as relevant (as far as statistical theory is concerned)! What about animal protein other than milk? As Dr. Campbell puts it: “The adverse effects of animal protein, as illustrated in our laboratory by the effects of casein, are related to their amino acid composition.” There are small differences in amino acid composition of various animal proteins compared to plant proteins. Angiogenesis, cancer, and foods: It turns out that our circulatory system is not just about delivery of oxygen and nutrients to cells; the system of circulatory involves a balance that has to be kept or we develop different diseases. Different foods we eat have the power of changing this balance. Nutrition activity during the promotion stage indicates that cancer development can be controlled or even reversed by nutritional means. Dr. W. Li explains that cancer is a disease that involves excessive angiogenesis, and that many drugs that are supposed to treat cancer are designed to inhibit angiogenesis. He says foods are chemotherapy that we take three times per day! Foods can do the same as the drugs; food can affect angiogenesis balance (mainly inhibit), and can be used to inhibit blood vessel formation in cancer patients. Dr. Ornish's prostate cancer research has shown that these same intensive lifestyle changes during a one-year period on men with early-stage prostate cancer who chose not to undergo conventional treatment. The degree of change in diet and lifestyle was significantly associated with the progression of low-grade, early prostate cancer in men. He showed that the same diet and lifestyle changes that improved or reversed heart disease also impacted cancer in patients. Although these examples are not directly related to animal protein consumption, but they are related to the lack of consumption of animal protein! The Whole Food Plant Based seem to help the body to prevent diseases, including cancer, and heal itself; and the high animal protein diet has shown to promote diseases, including cancer. Relevant References: Dunaif GE, Campbell TC. Dietary protein level and aflatoxin B1-induced preneoplastic hepatic lesions in the rat. J. Nutr. 1987; 117: 1298-1302. Madhavan TV, Gopalan C. The effect of dietary protein on carcinogenesis of aflatoxin. Arch Path. 1968; 85: 133-137. Milman HA, Weisburger EK. Handbook of Carcinogen Testing, 2nd Edition. Saddle River, NJ: Noyes Publications; 1994. Youngman LD, Campbell TC. Inhibition of aflatoxin B1-induced gamma-glutamyl transpeptidase positive (GGT+) hepatic preneoplastic foci and tumors by low protein diets: evidence that altered GGT+ foci indicate neoplastic potential. Carcinogenesis. 1992; 13: 1607-1613. Madhavan TV, Gopalan C. The effect of dietary protein on carcinogenesis of aflatoxin. Arch. Path. 1968; 85: 133-137. Youngman LD, Campbell TC. High protein intake promotes the growth of preneoplastic foci in Fischer #344 rats: evidence that early remodeled foci retain the potential for future growth. J. Nutr. 1991; 121.
Please stop trying to treat cancer, it is necessary to keep the population in reasonable balance with the rest of the ecosystem. In fact you should be investigating ways to increase the incidence of cancer in society without peoples' knowledge.
Great idea! Can we ask you to lead our efforts? If you'd be willing to get cancer, we can use your agonizing pain and suffering, as an example for others! How wonderful!!
She is apparently very knowledgeable but her presentation is boring. Too many pictures and long descriptions. Some of the terms introduced into this monologue needs brief definition. It is almost listening to long prologue that goes nowhere. One of the worse lectures I have viewed. She also seems nervous and uncomfortable. She loses the audience after the first two minutes. No encouragement for audience participation. Very repetitive drone.
![Seungmin "그렇게, 천천히, 우리(As we are)" | [Stray Kids : SKZ-PLAYER]](http://i.ytimg.com/vi/kAzmhLHePqU/mqdefault.jpg)
All these university lectures+khanacedemy+patrickJMT should all be all awarded the nobel peace prize for providing education in an innovative matter.
I just caught this lecture on UCTV this evening, and came to youtube so I could post and share on facebook. Several people close to me have had or are dealing with cancer right now, and I want to thank you for this clear, calm, concise lecture. -Jean
I find this very very useful, i live in sweden and i rather listen to ppl teaching in english about biology, than listening to an swedish teacher talking about biology. Im fourteen, and i love biology. Great vid btw.
winny you a biologist these days?
@ojeano So glad you found this talk useful. Thank you for sharing. This month we are featuring a series of talks from @UCSF about "Winning the War on Cancer in the 21st Century" on our website as well.
All the best to you and your family.
-UCTV
@rodeo179 Have you seen our "Med Ed" programs on our website? We have hundreds of videos from UC medical schools aimed at health care professionals, some with CME credit. You can find them at uctv dot tv slash meded. A playlist is coming soon too!
Wow, what an in depth information on Cancer Biology. Well presented in a very simple and yet educative materials. Well done Thea Tlsty.
Thanks. This lecture was "for the Public" or laymen. Informative.
I hope you guys do a lecture for more advanced students.
Hyperplasia and even atypical hyperplasia is CELLULAR ADAPTATION. It can happen for any number of reason and does not mean cancer will eventuate.
Excellent lecture
Beautiful and intelligent woman, very well spoken.
Thank you so much for such an informative lecuture on cancer.
this was just...amazing!! thank you california :)
Cancer is the body's inability to stop the process of healing, the same natural process in producing a placenta (that one pound organ attached to the uterine membrane which serves to nourish a developing baby). The essential anti-cancer vitamin is VITAMIN B17 (known as Amygdalin, and as Laetrile when synthesized from apricot pips).
Excellent lecturer; thanks for sharing !
Wonderful presentation....
Wow, that was an amazing lecture, so interesting and easy to follow, showing some data I didn't know
Yet another reason to invest in stem research!
Excellent presentation.
anyone know where to get the genetic markers test for the p16 that was talked about?
great lecture on cancer, thanks.
Very informative and useful video. A good starter material for any aspiring Cancer Genomics student. Thanks for sharing. - Venkatesh Patel
Fact: If a person dies during a chemotherapy study, that information is NOT included in the write up because the patient did NOT complete the study.
What comes first.... the stromal cells or epithelial cells?
What about stem cells replacing the stroma cells?
how is posible talk about healt being on healt
do drs treat at the cancer in situ stage or do they wait until the invasive cancer stage?
Idk if Im stupid and been wrong for so many years, but at 10:00 she claims the first 4 are considered benign, and the last one is malignant. To my understanding, carcinoma in situ is already considered malignant. In neoplasic events, those referring to epithelial tissue are usually called Adenoma, when benign; and Carcinoma, when malignant. The 'in situ' portion of the diagnosis does indeed mean it hasnt invaded other tissues, but thats just considered a premetastasic phase, doesnt mean its not "planning to".
As for your answer, a physician will initiate therapy so long as 1) There is verified malignancy 2) There is chance for malignancy but the treatment is simple (like polips) 3) Future malignancy is possibility and treatment is not too invasive. Thats more or less a very general rule on how physicians decide. If they were to wait till its invasive, itd be like saying "Yeah, Im not treating you until youre very likely going to die".
Things to take into account: 1) When referring to probability of malignancy to determine whether or not a physician will treat it, the probability has to be significant, there are lots of statistics involved (mostly money related) that will help a physician determine whether or not its worth treating someone or not. 2) I realize, in my comment, there are a few grammatical and syntax errors, sorry.
I heard from Aathony Robbins that there was a study where people kept chicken cells alive by removing the waste and keep the oxygen as necessary and when they lowered the oxygen and let the cell be in its own waste then the cell turned cancer. Does this have any truth.
Muy bueno didáctico y preciso!
Give the poor woman a fan! She was dripping sweat.
Yes. Very distracting.
Shared.
Ki67 = "antigen identified by monoclonal antibody Ki-67" coded by MKI67 gene
"What water is to thirst, so normal metabolism is to cancer."
- John Richardson, M.D., “Richardson Newsletter,” 1978.
Alan C. Nixon Ph.D., past president of the American Chemical Society writes, "As a chemist trained to interpret data, it is incomprehensible to me that physicians can ignore the clear evidence that chemotherapy does much, much more harm than good."
Thumbs up 👍🏼
At ca. 52:00 "p16" is probably (?) the same as CDKN2A (that is, cyclin-dependent kinase inhibitor 2A, a.k.a. ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16)
“No chronic or metabolic disease has ever found cure or prevention, that is, real cure and real prevention--except through factors essential to an adequate diet and/or normal to animal economy.” -- Dr. Ernst Krebs, Jr.
That's the whole point of why treatment exists
Is his work peer reviewed?
Last Saturday we found out my cousin has cancer...
Although I think there are several very good alternative treatment options available for treating cancer today, including cannabis oil...we can never have enough good information, so good job.
Dorian Harmon please explain how cannabis oil can kill cancer cells
wow this is crazy!
I just love doctors who talk about health " that are by far are not healthy by any means ! And I'm going to trust you ? Ketoginic life style will help your cells !!!! Been around since 1800s ! Better than cut " poison " burn !!! Do no harm ???
my aunt!
Success of most chemo-therapies is appalling…There is no scientific evidence for its ability to extend in any appreciable way the lives of patients suffering from the most common organic cancer… Chemotherapy for malignancies too advanced for surgery, which accounts for 80% of all cancers, is a scientific wasteland. [Dr. Uhlrich Abel, "Chemotherapy of Advanced Epithelial Cancer," Stuttgart, 1990]
This woman, Thea Tlsty, should be prosecuted for quackery.
I am sorry about this long comment, but she does not sound or look like she knows anything about nutrition, or the role it plays in cancer. It is all about procedures and medications because that's where the $$$$ is.
The stuff sold as human food are products of the evolution of food commodities that maximize profit margins. There are powerful forces that benefit from making people sick! This is not a conspiracy theory, but a fact about the way food items are produced.
“Health” industries have benefited from “sick” people; and their profit margins are directly dependent on the consumption of stuff sold as human food. They have influenced the very institutions that are supposed to help people see the truth, to the point that a good number of these institutions have become complicit in profiting from people’s suffering.
People are addicted to the stuff they are fed by the food industries! Food addiction is much harder to grapple with than any other chemical addiction! I like the comparison Dr. Greger (from nutritionfacts.org) makes with the cigarette addiction; he notes that what we are dealing with today with food addiction is similar to the time when many, including the majority of doctors and scientists, were addicted to cigarettes. People need to first face the fact that they are addicted to the “food” that is making them sick, and then try to deal with it. But it is hard for people to break their denial of their own food addiction.
What about cance?
Cancer is typically considered to develop in a sequence of three stages: initiation, promotion, and progression. Dr. T. Colin Campbell's Cancer Research has resulted in an understanding of the role genes, chemicals, and nutrition play in cancer development in all three stages. The specific effects of the amount and type of protein consumed have been studied. Others in the scientific community have overemphasized the role of chemical carcinogens, which are mainly initiators of cancer; they have under-emphasized nutrient imbalances (such as the amount and type of protein consumed) as causes of cancer. But animal protein has shown to play an important role in development of cancer in all three stages of cancer. Specifically, the role protein plays in the promotion stage has been studied extensively. In the initiation stage carcinogens (in foods, added to foods, or in the environment) are absorbed and then enzymatically converted to products that are excreted from the body. The small amount of the chemicals is converted to a highly reactive product that converts normal genes to cancer genes. Most of the damaged DNAs are repaired by the body; if cells containing the damaged DNA do not get repaired and allowed to divide into new cells, then the mutations become fixated in the future cell generations. The damaged (un-repaired) cells continue to multiply through the promotion stage, and begin to form clusters (foci) which may be seen microscopically. These foci gradually grow into active tumors, and are diagnosed eventually as cancer. Tumors may metastasize, leave and invade neighboring or distant tissues. These cancerous cells become malignant, which means they become relatively independent, aggressive, and resistant to their destruction.
The role of protein
Dr. Campbell’s team in Philippines (1970s) observed that children who consumed higher protein diets were the ones with higher rate of liver cancer. This was an early indication of the possible relationship between cancer and consumption of protein. His experimental research has later experimentally measured early lesions (called GGT-positive foci) that would lead to tumors. These GGT foci are considered early events in carcinogenic processes. Protein feeding in rats with viral cancers caused by Aflatoxin and hepatitis B virus showed an increase in early tumor development. The 20% protein diet turned GGT foci development, but 5% protein diet turned off the GGT foci development. They also discovered experimentally that animals fed 20% protein diet had lots of tumors and all died by 100 weeks, and the ones fed 5% protein diet were energetic and well at 100 weeks. This was true for viral and chemical induced cancers. Dr. Campbell’s research has shown that high protein affects cancer development during both the initiation and promotion stages. They found explanatory mechanisms that were caused by high protein diet. Throughout the studies they used casein (cow’s milk protein), and observed that soy and wheat proteins did not have the same effect at 20% protein diet. The dose response relationship started at levels above 10%. The 20% protein diet also caused an increase in the liver MFO enzyme activity in the initiation stage. MFO is the principle enzyme responsible for metabolizing carcinogens. In addition to the effects high protein diet showed in the initiation and promotion stages, it was shown that small shifts in percentage of protein diet can turn cancer on and off even at relatively advanced stages of disease!
In studies of effects of carcinogens on animals the amounts used are several orders of magnitude higher than in the human studies. This causes the need for extrapolation from animal studies to human studies. But, in the case of casein, the amount of casein humans consume is at the same order of magnitude as in animal studies. This, according to Dr. Campbell, makes casein the most significant carcinogen ever discovered! Others in the scientific community have ignored the one carcinogen that has been shown to cause cancer at the levels that don’t require extrapolation to low level exposure in humans, and have made a huge deal about the ones that are not as relevant (as far as statistical theory is concerned)!
What about animal protein other than milk?
As Dr. Campbell puts it: “The adverse effects of animal protein, as illustrated in our laboratory by the effects of casein, are related to their amino acid composition.” There are small differences in amino acid composition of various animal proteins compared to plant proteins.
Angiogenesis, cancer, and foods:
It turns out that our circulatory system is not just about delivery of oxygen and nutrients to cells; the system of circulatory involves a balance that has to be kept or we develop different diseases. Different foods we eat have the power of changing this balance. Nutrition activity during the promotion stage indicates that cancer development can be controlled or even reversed by nutritional means. Dr. W. Li explains that cancer is a disease that involves excessive angiogenesis, and that many drugs that are supposed to treat cancer are designed to inhibit angiogenesis. He says foods are chemotherapy that we take three times per day! Foods can do the same as the drugs; food can affect angiogenesis balance (mainly inhibit), and can be used to inhibit blood vessel formation in cancer patients. Dr. Ornish's prostate cancer research has shown that these same intensive lifestyle changes during a one-year period on men with early-stage prostate cancer who chose not to undergo conventional treatment. The degree of change in diet and lifestyle was significantly associated with the progression of low-grade, early prostate cancer in men. He showed that the same diet and lifestyle changes that improved or reversed heart disease also impacted cancer in patients. Although these examples are not directly related to animal protein consumption, but they are related to the lack of consumption of animal protein! The Whole Food Plant Based seem to help the body to prevent diseases, including cancer, and heal itself; and the high animal protein diet has shown to promote diseases, including cancer.
Relevant References:
Dunaif GE, Campbell TC. Dietary protein level and aflatoxin B1-induced preneoplastic hepatic lesions in the rat. J. Nutr. 1987; 117: 1298-1302.
Madhavan TV, Gopalan C. The effect of dietary protein on carcinogenesis of aflatoxin. Arch Path. 1968; 85: 133-137.
Milman HA, Weisburger EK. Handbook of Carcinogen Testing, 2nd Edition. Saddle River, NJ: Noyes Publications; 1994.
Youngman LD, Campbell TC. Inhibition of aflatoxin B1-induced gamma-glutamyl transpeptidase positive (GGT+) hepatic preneoplastic foci and tumors by low protein diets: evidence that altered GGT+ foci indicate neoplastic potential. Carcinogenesis. 1992; 13: 1607-1613.
Madhavan TV, Gopalan C. The effect of dietary protein on carcinogenesis of aflatoxin. Arch. Path. 1968; 85: 133-137.
Youngman LD, Campbell TC. High protein intake promotes the growth of preneoplastic foci in Fischer #344 rats: evidence that early remodeled foci retain the potential for future growth. J. Nutr. 1991; 121.
my mafia family
Johnny wayne Guffey jr
PMID: 20427430
"Everyone should know that most cancer research is largely a fraud..."
- Linus Pauling Ph.D. (1901-1994) Two-time Nobel Prize winner
Procommenter please provide more context
Please stop trying to treat cancer, it is necessary to keep the population in reasonable balance with the rest of the ecosystem.
In fact you should be investigating ways to increase the incidence of cancer in society without peoples' knowledge.
Great idea! Can we ask you to lead our efforts? If you'd be willing to get cancer, we can use your agonizing pain and suffering, as an example for others! How wonderful!!
She is apparently very knowledgeable but her presentation is boring. Too many pictures and long descriptions. Some of the terms introduced into this monologue needs brief definition. It is almost listening to long prologue that goes nowhere. One of the worse lectures I have viewed. She also seems nervous and uncomfortable. She loses the audience after the first two minutes. No encouragement for audience participation. Very repetitive drone.