Point of clarity: The term transairway pressure is widely used to refer the pressure difference between the ends of airway(Mouth & Alveoli).( Ref: David and Joseph 2006 Respiratory critical care). But in this video the term is used to refer the pressure difference across the wall of the airways as used by some authors. (Ref: Medical Physiology 4/e by Rhoades and Bell Chapter 18. page 351). American Physiological society and American Thoracic Society recommends the use of the term Transmural pressure of Airways for describing pressure across wall of airways.
Wow. This was beautiful. This concept demands an in-depth and logical step by step explanation which other teachers try to dodge and it just doesn't work. Thank you so much. 😁
I’m glad it helped!! Please go through my other videos as well!! If you need clarification on any topic, leave it in the comment, I’ll try to make videos on them!! Happy learning 😊
Nice video doc . Regarding Trans airway pressure ,most of the books say it's the pressure difference between opening of the airway (mouth) and alveoli. Please Make a video on west zones of lungs. Thank u
I have been struggling to understand this after looking at countless videos, articles and presentations all over the internet and through my uni resources. This video is superb and helped me understand it perfectly and much better than anything else...thanks so much! And keep up the great work :)
Increase in resistance would decrease the flow. If the flow is lesser then the pressure drop is greater. In other words pressure is lost in overcoming resistance. I hope that makes it clear.
In Emphysema there is destruction of alveolar wall resulting in decreased elasticity of lung. Smaller airways are kept patent by pulling of nearby alveolar wall. So, without support the airways becomes smaller and airway resistance increases!! Elasticity of alveolar wall is required for recoil during expiration. Loss of Elasticity result in decrease in expiration and overinflated alveoli.
Amazing sir . And a doubt .Will atm pressure and intra alveolar pressure all equal? What's the role of pressure exerted by watervapour in airways? Does it tend do decrease the 760 mmhg?
Total air pressure can be same at two point with different constituents at each place. In the alveoli, let’s say the total air pressure is 760 mm Hg, it includes the 47 mmHg of water vapor( partial pressure)also. Partial pressure of other gases will slightly decrease because of dilution by water vapor. So total pressure (760) might remain same, but partial pressure of all gases will differ when comparing atmospheric and alveolar air.
And also why the EPP is shifted in these patients sir ? In copd residual volume increases so that intrapleural increases than the normal. Is this the reason ?
When the resistance to airflow increases, the pressure drop becomes steeper. Intra bronchial pressure drops because of higher resistance in obstructive lung diseases. As the pressure quickly decreases it becomes equal to intra pleural pressure at a lower point in the airways.
Sir, why is RV TLC ratio increased in neuromuscular diseases of restrictive pathology? And why is RV TLC ratio normal in chest wall diseases like kyphoscoliosis(restrictive lung disease)? Pls clarify sir
The RV is determined by ability of expiratory muscles to compress the chest wall. In NM diseases with expiratory muscle weakness, lungs cannot be squeezed well, so RV is higher and RV/TLC is also higher!! In chest wall deformities the TLC is low because of the structural deformity but the RV is normal or decreased, since expiratory muscles function normally. So RV/TLC may be normal.
Dyspnea is a symptom which happens in many diseases. The underlying pathology determines the EPP. In general, higher airway resistance, lower lung volumes and higher pressure outside the airways causes EPP move towards alveoli!
Thank you a lot sir! Super precise explanation, without any logical leap. I wish all professors could explain this way!
Thanks for the feedback!
As a college teacher its very useful in clearing my long term confusion.thank u sir.
Point of clarity: The term transairway pressure is widely used to refer the pressure difference between the ends of airway(Mouth & Alveoli).( Ref: David and Joseph 2006 Respiratory critical care). But in this video the term is used to refer the pressure difference across the wall of the airways as used by some authors. (Ref: Medical Physiology 4/e by Rhoades and Bell Chapter 18. page 351). American Physiological society and American Thoracic Society recommends the use of the term Transmural pressure of Airways for describing pressure across wall of airways.
Hi sir,Please make a video on Yesterday's jipmer questions
+Pa Zuzu thanks for the request. I am also planning to make such Q &A videos.
Wow. This was beautiful. This concept demands an in-depth and logical step by step explanation which other teachers try to dodge and it just doesn't work. Thank you so much. 😁
Thanks for the feedback! 😊
Thank you, just what I needed to understand breathing mechanics during forced expiration in patients with COPD
Sir you just saved me from another Physiology-induced mental breakdown. I cannot thank you enough!
You`ve made it very simple and clear Doc. Thank you so much. we really appreciate your effort.
+Rahaf Rafa I'm glad to hear that. Thank you.
the simplified version of all the gruelling theories of the big books. thanks sir for making it so awesome.
+ved ratna pathak you're welcome. Thanks for the feedback
Sir , you made such a complicated topic so simple to understand . All I can say is OUTSTANDING . Thank you soo...... much.
Glad to hear. Thanks for feedback
You made it easy to understand
Thank you very much
Very good explanation to an issue which is falsely understood by many (including me, but not anymore ;) )
just a little question to show you that you did understand nothing- why during the phase of inspiration once Palv reaches -1 the curve goes upwards
Sir... That was an amazing explanation..!! Fully registered. One of the difficult topics of respiratory physiology.
Thanks! Yes, indeed it’s a difficult concept.
Amazing explanation.....thankyou sir for clarifying this concept.....
You are welcome
Finally got my doubt cleared. Loads of thanks.
Excellent presentation sir .thanku
This was very helpful.....i understood the concept .Thank yku
Thank you so much! It really helped me so much to understand the reason behind pursed lip breathing!
Wow. Thanks. I really had quite a few ah-ha moments there. Thanks!!
I was struggling in this topic.. but sir u made it crystal clear.. thnx alot
I’m glad it helped!! Please go through my other videos as well!! If you need clarification on any topic, leave it in the comment, I’ll try to make videos on them!! Happy learning 😊
Nice video doc . Regarding Trans airway pressure ,most of the books say it's the pressure difference between opening of the airway (mouth) and alveoli. Please Make a video on west zones of lungs. Thank u
+prashanth thota you're welcome. Thanks for feedback and the request too!! I'll try my best.
Very helpful. Thanks
Very nice explanation.... Great job sir 👍
Glad it helped. Thanks
Great video sir
Beautifully explained by you, sir..thanks for sharing❤️
Thank you! 😊
Thank you sir ..nice explanation
worth the watch. up to the point.
Thanks
Superb!! thank you so much
I have been struggling to understand this after looking at countless videos, articles and presentations all over the internet and through my uni resources. This video is superb and helped me understand it perfectly and much better than anything else...thanks so much! And keep up the great work :)
+Divyansh Dixit. Thank you so much for the feedback!! I'm working on new videos!!
Thank you so much! I was struggling with this concept a lot, you explained it really well
Glad to hear that!
Excellent video. It would be helpful if it was also explained why the increased resistance causes decreased pressure.
Increase in resistance would decrease the flow. If the flow is lesser then the pressure drop is greater. In other words pressure is lost in overcoming resistance. I hope that makes it clear.
Thank you very much
That clarified a major doubt! Thank you so much sir.
Glad to hear that!!
great clarification ,Thanks sir
best wishes
You’re welcome
Very nice video all doubts are cleared
Perfect! Thanks, teacher!
You saved my life!! THANK YOU!!!
😊 you’re welcome
Thank you so much sir 🙃❤ Finally 🙏🙏I got it.
You are welcome 😊
I really appriciate to your effort... thank u sir for explaining this concept
Glad to hear!! Thanks for the feedback!!
Excellent explaination..
Thanks
Very Nicely explained !!
Thanks
It was very helpful! Thank you!
Thanks for the feedback
excellent sir
Lovely video sir.thank you
You’re welcome 🙂
Just fabulous= way better than the respiratory phys textbooks!
Thanks for the feedback Erica Sanderson
Wow that was a perfect explanation. Thank you
sir it ia really helpfull to me.......thanks a lot sir
You are welcome
Thanks for making it simple
Thanks for watching
phenomenal video doc! thank you very much. you made such a complex concept so easy to understand.
+Karthik Ramalingam thanks for the compliment
crystal clear explanation...
Thank you sir...!!😃
Great explanation!
Phenomenal explanation, thank you!
You’re welcome 😊
Very well and beautiful concept, it would be helpful if you have spoken a bit faster ,has to watch to video at 2x
yo.. i finally get it .. thx bro
Excellent explanation. Thank you!
Thanks for the feedback!
Thank you so much sir. You’re such a blessing
Well explained sir. Thanks for sharing
Good explanation sir
Very nice explanation mate!
Wonderful sir
Thanks
Very well explained sir. Thank you!
You're welcome
Thank you very much !!!! I am looking for good explanation like this.
Very nicely explained..!! Thank you so much ..!!
Really your videos very helpful .. it simplified every thing for us thanx a lot !
+R I am very glad to know it helped, thanks for comment
How simple it became .. thank you sir
+Hajer Alnasseri you're always welcome. Your feedback is very important for me. Thanks a lot!!
Clearly understood 👍
Thank u soo much sir
Thank you
Great and clear explanation! Thanks Dr. S!
+Sabri Conde-Yassin you're welcome. Thanks for feedback
thanks for uploading this. Your video cleared so much of my concepts. A million THANKSS!! :D
You are welcome. Thanks for the comment Ali
I was looking for a video that explains this but I found nothing ! great explanation doctor thank you !
Mucahid Akin thanks for the comment
Thank u sir...made it very easy
Underrated video
Great clearcut video. Thank you prof!!
You're welcome Mah Chia Ling
Thank you sir!
You’re welcome
So helpful 😊
Well explained... Thank you!
You’re welcome!
Thank you! This really helped
Thanks for the feedback
Always creative , thank you
+ALMAYYASAH ALKHARUSI Thank you for the kind words. You're always welcome.
Thank you!
too clear and simple ... thanks dr
Thanks for the feedback Basant
I assume that the air empties more quickly in the 'sick' lung because of Bernoulli's law, which gives a drop in pressure too early?
Transthoracic pressure is the pressure difference between pleural pressure and atmosphere pressure.
very helpful! appreciate your effort dr.
+ali al-dujaili many thanks for the feedback
Very helpful
Loved the video sir ...,.
Just one doubt ....
Can u explain what happens in emphysema ?
In Emphysema there is destruction of alveolar wall resulting in decreased elasticity of lung. Smaller airways are kept patent by pulling of nearby alveolar wall. So, without support the airways becomes smaller and airway resistance increases!! Elasticity of alveolar wall is required for recoil during expiration. Loss of Elasticity result in decrease in expiration and overinflated alveoli.
Thank you so much! that was such a great and useful video :)
+albybarman I'm glad it helped!! Thanks for the feedback
Amazing sir . And a doubt .Will atm pressure and intra alveolar pressure all equal? What's the role of pressure exerted by watervapour in airways? Does it tend do decrease the 760 mmhg?
Total air pressure can be same at two point with different constituents at each place. In the alveoli, let’s say the total air pressure is 760 mm Hg, it includes the 47 mmHg of water vapor( partial pressure)also. Partial pressure of other gases will slightly decrease because of dilution by water vapor. So total pressure (760) might remain same, but partial pressure of all gases will differ when comparing atmospheric and alveolar air.
@@ThePhysiologyChannel thank you so much sir !!
And also why the EPP is shifted in these patients sir ?
In copd residual volume increases so that intrapleural increases than the normal. Is this the reason ?
thankyou sir
You’re welcome!!
excellent lecture .superb
Thanks Dinakaran
you dont explain, why during inspiration the Palv has a sinosoid form
u killed it man !!!!!!!
+med tubeplus thank you:)
brilliant !!!
Thanks
Sir, why does equal pressure point drop to lower level in obstructive lung diseases.??
When the resistance to airflow increases, the pressure drop becomes steeper. Intra bronchial pressure drops because of higher resistance in obstructive lung diseases. As the pressure quickly decreases it becomes equal to intra pleural pressure at a lower point in the airways.
Thank u sir
really helped me! Thank you!
+Holland Stuart you’re welcome. Thanks for the feedback
superb explanation
+Praveen upadhyay Thanks
Sir, why is RV TLC ratio increased in neuromuscular diseases of restrictive pathology? And why is RV TLC ratio normal in chest wall diseases like kyphoscoliosis(restrictive lung disease)? Pls clarify sir
The RV is determined by ability of expiratory muscles to compress the chest wall. In NM diseases with expiratory muscle weakness, lungs cannot be squeezed well, so RV is higher and RV/TLC is also higher!! In chest wall deformities the TLC is low because of the structural deformity but the RV is normal or decreased, since expiratory muscles function normally. So RV/TLC may be normal.
Thankuuu sir!
Kindly post more videos of respiratory physiology
Thank you sooooo much 😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭
You’re welcome 😊
superb sir...
Thanks Santhosh
Brilliant! Thank you
Thanks for the feedback
I just have one questions, why does the pressure in the airways decrease faster with increased resistance?
What happens to the epp while the person experiences dyspnea?
Dyspnea is a symptom which happens in many diseases. The underlying pathology determines the EPP. In general, higher airway resistance, lower lung volumes and higher pressure outside the airways causes EPP move towards alveoli!
@@ThePhysiologyChannel thanks for the info :)
You are welcome!