Thank you very much for creating this video lesson. It is very well presented, paced, providing a detailed explanation of the cholera MOA. The animations are excellent. Thanks a million!!!
I literally went through so many videos and finally landed here where and was pretty sure wont be finding what i was looking for. But the it flipped my thought. THIS WAS EXACTY WHAT I WAS LOOKING FOR. thanks man.
I was having a hard time understanding how increased cAMP will result in diarrhea. It explained it clearly and also taught a couple other interesting things along with it. Thank you.
thank you for this video! I have seen so many youtube videos about this biological process and this is the best to comprehend rapidly the mechanism of adp-ribosylation in G-alfa! keep supporting others
You missed 1 part which is that the cholera toxin FIRST goes to the Golgi Apparatus and THEN to the ER. The A2 unit of the toxin has aa KDEL motif which allows binding to the KDEL receptor. This allows transportation of the toxin fomr the Golgi to the ER. Also the way in which the A part can get from the ER to the cytosol is interesting. The A part is unfolded in the ER by a chaperone. The ER wants to get rid of it, so it transports the unfolded A unit over the plasma membrane into the cytosol. Here the A part refolds itself and it can exert its effect on the GTPase.
My son was having loose stools and vomiting for five to six days. His stools were watery and blood pressure went down. We rushed him to hospital and Dr. diagnosed him with Cholera. Antimicrobials were given to him. He got symptomatic relief but not permanent relief. One day I shared my problem with one of my friend. He told me about Planet Ayurveda. We visited there and met Dr. Vikram Chauhan. Dr. said that my son's digestive system has become weak and gave us Digestion support capsules. Now my son is absolutely fine and his symptoms are resolving very fast.
Thank you for pointing this out. I fixed it. Usually all my videos are cited properly...I think I forgot to provide the citation when the video was first posted.
the clearest and most detailed video........... thanx alot RJ A
This is the best video that I have ever seen about cholera toxin mode of action!
The clearest yet detailed explanation video on the topic. Thank you so much!
Thank you very much for creating this video lesson. It is very well presented, paced, providing a detailed explanation of the cholera MOA. The animations are excellent. Thanks a million!!!
this just saved me for my graduate biochemistry class.
Millions of thanks for this video....my life saver for exam...
This is the best video on RUclips which explains the mechanism of action of cholera toxin
I literally went through so many videos and finally landed here where and was pretty sure wont be finding what i was looking for. But the it flipped my thought. THIS WAS EXACTY WHAT I WAS LOOKING FOR. thanks man.
Best video I have watched explaining the pathological mode of action of cholera and detailed cell signalling cascades. Thank you for this.
wifey
@@ayonmukherji sir this is a wendy's
I was just looking for it.... Thank you sir you just saved me from my tomorrow presentation.
Excellent vedio.
Thank you so much... I'm preparing for my academic seminar and it's really explanatory...
just 4 hrs before the 2nd MBBS biochemistry viva! thankyou very much...
I was having a hard time understanding how increased cAMP will result in diarrhea. It explained it clearly and also taught a couple other interesting things along with it. Thank you.
Awesome sir
This is fascinating. This demonstrates the mechanism by which cystic fibrosis is protective against cholera.
Well we should not forget about the increased concentration of protein kinase A that can act on other proteins as well
the most obvious explaining I have ever watch.........thank you
the voice could be louder. But all in all a very good and informational video which helped me for my microbiology exam. thx
Thank you for sharing
Please share more awesome videos
❤❤❤❤❤❤❤❤❤❤❤
thank you for this video! I have seen so many youtube videos about this biological process and this is the best to comprehend rapidly the mechanism of adp-ribosylation in G-alfa! keep supporting others
amazingly explained, concise and clear
A very easy to follow video.... thank you yu just made everything more clearer
exactly what I was looking for! Thanks
great explaining
Much better explained than my teacher thank's a lot
Thanks for such nice and easy explanation with animation for better understanding!!!
Well explained
Thankyuuuuu so much .
Amazing explanation, thank you very much 👏
congratulations, on perhaps the best descriptive tutorial on the subject. Thanks
Excellent!
Best one
That is veeeeeerrrrrrrrryyyyyyyy helpful I can’t stress this enough
thanks for short and clear explanation
The best video I saw on this topic
Superb!!
Just an awesome video!!
very nice, thanks a lot
You missed 1 part which is that the cholera toxin FIRST goes to the Golgi Apparatus and THEN to the ER. The A2 unit of the toxin has aa KDEL motif which allows binding to the KDEL receptor. This allows transportation of the toxin fomr the Golgi to the ER.
Also the way in which the A part can get from the ER to the cytosol is interesting. The A part is unfolded in the ER by a chaperone. The ER wants to get rid of it, so it transports the unfolded A unit over the plasma membrane into the cytosol. Here the A part refolds itself and it can exert its effect on the GTPase.
Crystal clear concept of cholera toxins.. Plz make animated video on vision signaling..
The most clearest video
Thank you sir
HELPFUL 🌸
Thank you for this detailed video.
GREAT SIR
THANKS A LOT .
Short Video and very accurate
Greatly 🎉🎉❤
thank you ..good job mate
Amazing.
thanx alot RJ A
Cleared video thanks boy
Thank you.. this is what I was looking for👍🏼
Excelente, muchas gracias por compartir
Thanks for this video ,it 's soooo amazing.
Thank you !
very helpful, thank u
Thank you
Wow❤
thanku
My son was having loose stools and vomiting for five to six
days. His stools were watery and blood pressure went down. We rushed him to
hospital and Dr. diagnosed him with Cholera. Antimicrobials were given to him.
He got symptomatic relief but not permanent relief. One day I shared my problem
with one of my friend. He told me about Planet Ayurveda. We visited there and
met Dr. Vikram Chauhan. Dr. said that my son's digestive system has become weak
and gave us Digestion support capsules. Now my son is absolutely fine and his
symptoms are resolving very fast.
Thank u so muchhhhhhhhhhhh high
Thanks
Hello, I did not understand very well what the function of adp ribose is, could you explain it to me please? thanks
The GTP bound alpha subunit will be there if the ribose adp complex is bound to it and will continuously produce cycle amp when it is needed
Sorry when it is not neede
Nice
Shouldn't you credit the writers of "Microbiology, Fourth Edition" from wwnorton for this video? :)
Thank you for pointing this out. I fixed it. Usually all my videos are cited properly...I think I forgot to provide the citation when the video was first posted.
Thanx man!
I looooove u
Who's come from dr.turco lecture say hi 😆
المهم الحل للقضاء على الكوليرا اكتشفه علماء وزارة الصحة الجزائرية و هذا بردم عين يشرب منها الناس في بلدية حمر العين بدلا من تعقيمها
💖💖💖
Marque page 3:16
🏅🏅🏅🏅
هم مننجح
#2:17
kinda bland but its ok
Nice
Thank you