Robertsonian translocation: 21q14q

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  • Опубликовано: 7 окт 2024
  • What's the chance that a man with a 21q14q Robertsonian translocation will have a child with Down's syndrome?

Комментарии • 85

  • @haseebali2164
    @haseebali2164 2 года назад +36

    This is THE best lecture on Robertsonian translocation. So much better than most resources even paid ones.
    You deserve all the appreciation.

  • @kaybenjamin6003
    @kaybenjamin6003 7 лет назад +39

    This is the BEST explanation I have ever found of this! Thank you!

  • @thanigeshrajsankar921
    @thanigeshrajsankar921 7 лет назад +10

    wow,, ! i hav been scratching my head for many hrs. Thanks for clearing. The best xplaination given by you which i cudn't find in other videos. thank you pal

    • @weteachmedicine
      @weteachmedicine  7 лет назад +1

      That's great to hear! Thanks for the feedback

  • @illainthesky929
    @illainthesky929 4 года назад +6

    So, the explanation was amazing. I was trying to understand this theme around 1 hour reading, then I found your video and you save me. Thanks :) Greetings from Peru...

  • @caitlinnguyen7254
    @caitlinnguyen7254 Год назад +3

    Literally best explanation of this ever. Our professor in class did not draw out the gamete possibilities and already had a picture showing them, so I was lost in an instant. Thank you very very very much!!!!!

  • @florashlaks
    @florashlaks 2 года назад +1

    Oh my God I cannot thank you enough! You've saved my time

  • @drmahadev5629
    @drmahadev5629 Год назад +1

    Exactly what i was looking for. Thanks

  • @AA-nd9fq
    @AA-nd9fq 2 года назад +1

    I understood this finally,the best explanation, thank you from Egypt ♥️

  • @daniel_schmidt.
    @daniel_schmidt. 4 года назад +13

    There's actually no single german video about this topic. Luckily, the technical terms are really similar in both languages, so I understood it. Thank you for the video, you explained it really well. Have a great day!

  • @heba1708
    @heba1708 Год назад +2

    You say thanks for watching! We are supposed to thank you for explaining like this, thank you 💗

  • @Lasitha2
    @Lasitha2 3 года назад +2

    This is the most clear explanation I ever came across! Thank you.

  • @samsaon7153
    @samsaon7153 2 года назад +3

    When you go through every possibility everything becomes more clear, thank-you ✨

  • @V99899
    @V99899 3 года назад +1

    Thank you for uploading this. This is amazing

  • @F91RPG
    @F91RPG 6 лет назад +6

    Best video ever! Save my medical genetics exam

  • @nourimoudache6886
    @nourimoudache6886 3 года назад +1

    thanks a million !

  • @ahmedal-mahdy4463
    @ahmedal-mahdy4463 Год назад

    Thank you very much for this absolutely clearful and amazing explanation, i will use it to explain this topic to my colleagues in arabic , thanks.

  • @tuanminhbui633
    @tuanminhbui633 Год назад +1

    thanks for your fantastic lecture, hope that there will be more in the future!!

    • @Geneesleer
      @Geneesleer Год назад

      Thank you for watching and for the compliment! Planning on making more videos soon.

  • @mojtabazare8071
    @mojtabazare8071 3 года назад +2

    I realy thank you this is perfect

  • @manuelgutierrez6170
    @manuelgutierrez6170 Месяц назад

    You did so great. Keep going, very good explanation!!

  • @matthewmillett1225
    @matthewmillett1225 4 года назад +2

    This was super clear and helpful. Thanks for the explanation and drawings!!

  • @tothemoon130
    @tothemoon130 5 месяцев назад

    Amazing lecture, thanks!

  • @blazejp0601
    @blazejp0601 2 года назад

    I've always had trouble visualising Robertsonian transolactions. This did the trick, just in time before the genetics exam

  • @backstagebaby4701
    @backstagebaby4701 3 года назад

    Thank you very much! Simply explained and thus well understood!

  • @hello.iselima
    @hello.iselima Год назад

    Thank you for this explanation, you save me

  • @paulobispo2197
    @paulobispo2197 6 лет назад

    Thank u!! I'm from Brazil and understand perfectly, thank u so very much. 😊

  • @naijanerd9572
    @naijanerd9572 3 года назад

    Thank you sir for this perfect explanation.

  • @nourhanahmed5804
    @nourhanahmed5804 3 года назад

    Thank you for this great explanation.

  • @manarterea8784
    @manarterea8784 4 года назад +2

    That was sooooo good !!! ♥️

  • @alinamandani6117
    @alinamandani6117 Год назад +1

    Amazing explanation!

  • @Killer10015
    @Killer10015 7 лет назад +1

    Thank you, great explanation, really helpful

  • @CutiePieDIY
    @CutiePieDIY Год назад

    thank you so much 😭😭❤️

  • @anustinnewsam13
    @anustinnewsam13 7 лет назад +1

    Finally helped me understand this!

  • @Maddawg31415
    @Maddawg31415 2 года назад

    Super helpful thank you so much!

  • @miguelorozco4109
    @miguelorozco4109 3 года назад

    The explanation was very good, thank you!

  • @kamber95
    @kamber95 7 лет назад +2

    Amazing. Very concise. Thank you :)

  • @bloodypowerbp5910
    @bloodypowerbp5910 11 месяцев назад

    It's true what they say about the Indian guy explaining a topic, amazing

  • @coxiellaburnetii4034
    @coxiellaburnetii4034 4 года назад

    Thanx you are the best ❤❤❤

  • @IdkaCoolusername
    @IdkaCoolusername 7 лет назад +2

    I didn't need this... but great work.

  • @kevinl1285
    @kevinl1285 Год назад

    Legend!

  • @1rrrrrrrrrrr544f
    @1rrrrrrrrrrr544f Год назад

    Great job ❤❤❤❤❤❤❤

  • @sokinahnasser6065
    @sokinahnasser6065 4 года назад

    Best video 👌🏻👌🏻👌🏻👌🏻💯💯💯💯 ,, highly recommended

  • @rotellezG
    @rotellezG 3 года назад

    I read that there are actually 4 kinds of meiosis resulting cells, because the 14q 21q cromosome is beside the 14 cromosome, and the 21 cromosome is alone, so 14q 21q cromosome can't go with the 14 cromosome towardsthe same side of the cell. Resulting in just 4 kinds of meiosis resulting cells.

  • @animeboi4010
    @animeboi4010 Год назад

    Still helpful after 6 years

  • @mahmoudelshrbine6218
    @mahmoudelshrbine6218 4 года назад

    Really helpful .... Thank you 🌸🌸🌸

  • @kavitaprabhugaonkar5112
    @kavitaprabhugaonkar5112 6 лет назад

    nicely explained.. thank you

  • @anna-mariakhalil5588
    @anna-mariakhalil5588 3 года назад

    love this

  • @superspeederbooster
    @superspeederbooster 3 месяца назад

    Unfortuantley real life numbers are way different.

  • @abdellahezahraoui4774
    @abdellahezahraoui4774 5 лет назад

    Best video ever

  • @turinturambar5946
    @turinturambar5946 Год назад

    Why is there a difference in the chances of a child being born with down syn. as opposed to a living child being born with down syn. being ( 1/6 vs 1/3 ) ? Confused me a little bit.

  • @asyed1497
    @asyed1497 6 лет назад

    Phenomenal.

  • @hiraishfaq675
    @hiraishfaq675 5 лет назад

    great job

  • @abdellahezahraoui4774
    @abdellahezahraoui4774 5 лет назад

    merci beaucoup

  • @seraphczx3466
    @seraphczx3466 2 года назад

    is the proportion of six gametes really equal? I bet there is a difference among them. Really wanna prove it but I graduated and no longer have access to the lab equipment.....

  • @1rrrrrrrrrrr544f
    @1rrrrrrrrrrr544f Год назад

    Best explanation, but I have a question, for down's syndrome to occur ,we need three 21 chromosomes, in case of translocation,familial down's syndrome has 2 21 chromosomes, but third one isn't a complete 21 chromosome, are both primary and familial down's syndrome the same?

  • @Halitsavafoglu
    @Halitsavafoglu 6 лет назад

    Amazing! Thank you :)
    What's the chance that a (woman) with a 21q14q Robertsonian translocation will have a healthy child?

  • @ahmedrefaat7001
    @ahmedrefaat7001 5 лет назад

    Yr the best

  • @firasbaklouti8757
    @firasbaklouti8757 Год назад

    is it possible for the meiosis to give an empty daughter cell while the other has all 3 chromosomes?

  • @5omethingsBetterThanNothing
    @5omethingsBetterThanNothing 5 лет назад

    channel name didnt age well, but great video!

  • @uzayyolcusu6344
    @uzayyolcusu6344 9 месяцев назад

    Wowww thıs iş best

  • @stijnnuijten8626
    @stijnnuijten8626 4 года назад +1

    I love you

  • @muhamedshaban6087
    @muhamedshaban6087 6 лет назад

    Thaaaaanks

  • @WikkydGaming
    @WikkydGaming 7 лет назад

    Why can't you have all 3 on the same side of meiosis?

    • @WikkydGaming
      @WikkydGaming 7 лет назад +1

      In other words, why can't the dad also contribute the 14, 21, and the 14q/21q all in the same sperm?

  • @tahapondsuehara2345
    @tahapondsuehara2345 7 лет назад +1

    what about chromosome 2 fusion ?

  • @ahmedsayed9780
    @ahmedsayed9780 7 лет назад +1

    Really really brilliant , well done , good work but I think the chances of healthy child will be 1\3 not 2\3 as they r 2 from 6 which equal 1\3 we don't luv maths , I know 😃😃

    • @weteachmedicine
      @weteachmedicine  7 лет назад +2

      Thanks for the feedback, sharp! Indeed, the chance of a healthy child in total is 2/6. But the chance that a child that is alive is also healthy is 2/3. Indeed, I could have clarified this more.

  • @jessicam9783
    @jessicam9783 5 лет назад

    Which Robertsonian translocation would result in 2 out of 3 chances of the baby living? Does the chance vary from different types? Such as if instead of 21 and 14 being affected, 13 and 14?

    • @ambercouch3406
      @ambercouch3406 4 года назад

      I'm not sure if this answers your question but 14=miscarriage
      13= trisomy 13 and that can result in miscarriage, death shortly after birth or some live years it's really a shot in the dark with that one. Drs say trisomy 13 is incompatible with life but many times that's not the case

  • @alizatasnim4702
    @alizatasnim4702 4 года назад

    Why it only occurs in chromosome 13,14,15,21&22 PLZZ answer

    • @elenimvr
      @elenimvr 4 года назад +2

      Because they are acrocentric

  • @mohammadfadawi8577
    @mohammadfadawi8577 3 года назад

    Better of studying book for thousands hours. 👌🏻💙

  • @tn7773
    @tn7773 9 дней назад

    Ty. So much . U explained it very well...and so sorry fr this but ur writting is very bad😂, and more better if more examples were given like if mother is only carrier, if both parents are carrier and if either parent is carrier of translocation between 2 chr 21....i am writting all th options of my mcq.

  • @samvelaghajanyan4166
    @samvelaghajanyan4166 6 лет назад

    1.25x

  • @5omethingsBetterThanNothing
    @5omethingsBetterThanNothing 5 лет назад

    channel name didnt age well, but great video!