Plasma, constituents and functions
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- Опубликовано: 16 ноя 2015
- Plasma is a yellowish fluid which is about 91% water. This keeps the blood fluid, allowing it to circulate around the body. The rest of the plasma is made up of various substances in solution and suspension; these include plasma proteins, nutrients, dissolved gases and waste products.
Plasma proteins
Proteins are organic molecules made up of precise sequences of amino acids which are chemically bound together. There are three main plasma proteins; albumin, globulin and fibrinogen. Proteins are very large molecules and their presence is vital to generate plasma osmotic potential. Without this osmotic property the blood would be unable to reabsorb tissue fluid into the venous ends of the capillaries. Albumin is the most common plasma protein and also generates most of the osmotic potential of plasma. The globulin proteins include the immunoglobulins, also called antibodies, which allow the body to fight off infections. Without these immune proteins we would probably die from the next viral or bacterial infection we pick up. Other globulin proteins act as carrier molecules which transport some hormones and minerals around the body. Fibrinogen is a plasma protein which is essential for the process of normal blood clotting.
As fats are not soluble in water they are transported around the body bound to plasma proteins. These combinations of fat and protein are termed lipoproteins and are soluble in water.
Nutrients and waste products
Plasma carries absorbed nutrients from the gut to all of the tissues of the body which need them. These include glucose, amino acids and vitamins. It also transports waste substances such as ammonia from the tissues to the liver, where this poisonous waste is converted into urea, which is much less toxic. Once formed, the urea is transported in solution from the liver to the kidneys for excretion.
Other plasma components and functions
Plasma is a carrying vehicle for a range of dissolved salts in ionic form. These include sodium, chloride, bicarbonate, potassium, phosphate, magnesium and calcium. Plasma also carries some dissolved gases such as carbon dioxide, nitrogen and some oxygen. Most of the carbon dioxide transported by the blood is carried by the plasma. Plasma also transports endocrine hormones from glands to their target tissues.
Collectively the blood is important in transferring heat around the body, helping to regulate body temperature. Heat from warm, metabolically active areas, such as the muscles and liver must be transported away to prevent localised overheating. This warm blood can then be used to warm cooler areas such as the feet.
Blood is slightly alkaline. Arterial blood has a pH of 7.35-7.45, but venous blood is slightly more acidic with a normal pH of 7.35. This difference is caused by the increased volumes of carbon dioxide carried in the venous blood, some of which is carried as carbonic acid.
I am loving your lectures. Great refresher after a 20 year career break!
Thank you for this clear video! Very Helpful! I'm taking Pathophysiology and I need to know everything more in depth!
Amazing! I always use youtube to enhance what I'm learning and this is just great. Thank you!:D
simplified and I got to understand it so easily! thank you!
So helpful, thank you so much.
So simple to understand! Thank you
Thank you kindly. Very organized and easy to follow along .
Great teacher!!! Thank you!
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He is a good teacher and a helpful teacher. I love your teaching skills. Thank you.
This is so useful thanks 💯
Thanks Sir
very helpful
and the short note enhance the understanding
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clarity - thanks!
Thank you
Thank you Dr .John
from Jordan 🇯🇴
Thus was very nice thank you
Most Informative lecture ever sir I do appreciated you Courage love from Pakistan🇵🇰♥️
شكراً جزيلًا 👍🏻🇱🇾❤
I’ve been donating mine but I think I’m gonna keep it 🥳
I went to donate today as I usually do. Been donating over a year now. And today the nurse explained all of most of what you explained. My protein levels were to high. It scared me! She took a sample for next time to see if I can continue to donate. Now I’m guessing what I ate. But I do remember I didn’t eat much or probably that day. What could it be?
Top class lecturer
Thank you sir
You are the best!!! Do you tutor via zoom?
Thank you very much this was helpful, but I'm having trouble hearing what you said at 7:45-7:47
Can I ask why is it that for the magnesium ions it is written as Mg++ and not Mg2+
When plasma is used to be provided to a patient under trauma, is the plasma pre-prepared and filtered out from waste materials for example, or is it provided as is (from donor). Can plasma be artificially prepared?
No, it can not be produced in a lab or factory, it's always from a donor. There are other blood or plasma substitutes, but the real blood and plasma can only come form a donor.
❤sir
What proportion of the plasma proteins are made up of albumin?
40-70%
I appreciate this question. And like how you're thinking.
54%
3:53
This stuff is deep i guess. Probably should have floaties or prereq in the deep end. Gonna get finely regulated electrolytes for my homeostatic ++++ions or Gatorade asap.
Ive seen other lectures that mention hormones in the blood , so does iodine reauired to make only thyroid hormone specifically? Or all hormone function? Especially when the wastes nitrogen rubbish excretion in blood. Thanks again in advance. This lecture by itself is enough to make one wary of the toxin removal foot soak technology. Personally, it does seem legit in my experience, but the illusionist was more creative.
Sir, I am from Bangladesh and I have a little problem. Please explain my problem
My problem is microcirculation
I am going to watch your videos and i am going to pass my exams :P
So helpful, thank you so much.
@@santanazachariah2470 very interesting
@Colt Randall noice