Admittedly commenting before watching and I assume you mention this, but I hugely value not having a heart attack or stroke as well as not dying. Very much up there on my life goals for the next few years
I have seen this claim from a lot of low carb / keto influencers - This is why I now only get health information from sources that I can trust - like this channel and biolayne!
First thing I check in any published study is the gender/age participation breakdown. Statins are a class of drugs. Were all study participants on the same statin at the same dosage? So many variables to factor in. Appreciate the rational approach you always take, Dr C., and your clear presentation style!
What an incredible analysis. Thank you! I saw the so called doctors promoting not taking Statins based on this study. Now I know the fine print. Please keep this up!
Great video as usual, I think it's great the way you explain how to correctly interpret science and the pitfalls of just looking at headlines on social media or even mainstream media.
You DO deserve a medal for reporting this information. I've heard the "3-4 days" canard many times in the past from "reputable" sources, including internet doctors. Once again, you reveal how it's so important for an average person to also learn how to properly interpret scientific studies instead of simply relying on condensed headlines written by people who lack the education to understand what you explain here so well. Thank you again for literally saving our lives.
Solid video as usual Doc! A solid long term follow up using statins was published in the New England Journal of Medicine by Ilse and colleagues in 2019. They followed children with hypercholesterolemia who were initially randomized to statins for an additional 20 years and documented outcomes of heart disease compared to their parents. The children had notably fewer events. Below is a quote from the abstract. "The cumulative incidence of cardiovascular events and of death from cardiovascular causes at 39 years of age was lower among the patients with familial hypercholesterolemia than among their affected parents (1% vs. 26% and 0% vs. 7%, respectively)." So a 25% difference in occurrence of CVD events risk in the children and no death seen.
Great explanation, thank you. I wonder why some studies use expected life extension, while others use hazard ratio (increase or decrease of risk during a time period). It seems hazard ratio is much more understandable.
I just wish I had started statins sooner. My uncle had a mild heart attack in his late 40's and started statins after his recovery.He died a few years ago at 98.
So what is the purpose of a study like this? Given the predictability of how social media will distort the findings, it almost seems as if the study is designed to mislead.
I’ve been doing a ketogenic diet for several years, as it works well for me. But the anti-statin messaging in the low carb social media crowd is ridiculous.
My greatest sadness from this video is that Gil has to reduce the description of the methodology and statistics behind his opinions. I understand that need to keep his audience from losing their grasp. But still, 😭
Maybe they should consider using shrooms like Oysters, that contain a natural stating, lovastatin, and have high amounts of the longevity amino acid, ergothioneine.
Is this really a trial or is it sensentionalist nonsense, or trolling or, maybe a social experiment in seeing how many people actually read the study rather than just following what the "findings" suggest?
Apart from genetic causes of very low cholesterol, a level of around 50 in blood is fine.This is the level found in young children. Every cell produces its own cholesterol, so you never can have not enough.
You actually do deserve a medal for this. Very clarifying. 👏
I'm much more interested in the added days of health and vigor than the added days of life
I'd imagine most people are interested in doing both.
People say that a lot, and I get why, but in practice those are pretty correlated anyway.
What about quality of life? I’d argue that’s more important than lifespan.
Admittedly commenting before watching and I assume you mention this, but I hugely value not having a heart attack or stroke as well as not dying. Very much up there on my life goals for the next few years
Actually you do deserve a medal Gil 😁 Best health channel on RUclips!
I have seen this claim from a lot of low carb / keto influencers - This is why I now only get health information from sources that I can trust - like this channel and biolayne!
I'm far more interested in adding days of health and vitality than merely adding days to my life.
People tend to be more healthy and vital when they haven't suffered a heart attack or stroke or other consequences of cardiovascular disease.
First thing I check in any published study is the gender/age participation breakdown. Statins are a class of drugs. Were all study participants on the same statin at the same dosage? So many variables to factor in.
Appreciate the rational approach you always take, Dr C., and your clear presentation style!
My best friend of 64 years just had a stroke last Sunday (12/8/24). When your life is on the line, you will try anything.
Best wishes to him and yourself👍
Very nice that you included real long term estimates and not just dismissed the „social media claims“. This one was very helpful.
Thanks for this! I appreciate how you look at the big picture and then do the triple check.
What an incredible analysis. Thank you! I saw the so called doctors promoting not taking Statins based on this study. Now I know the fine print. Please keep this up!
Great video as usual, I think it's great the way you explain how to correctly interpret science and the pitfalls of just looking at headlines on social media or even mainstream media.
Solid breakdown Gil. Thanks!
You DO deserve a medal for reporting this information. I've heard the "3-4 days" canard many times in the past from "reputable" sources, including internet doctors. Once again, you reveal how it's so important for an average person to also learn how to properly interpret scientific studies instead of simply relying on condensed headlines written by people who lack the education to understand what you explain here so well. Thank you again for literally saving our lives.
Aseem Malhotra has left the chat 💬
Thank you for your unbiased honesty. I wish you long long life and high spirit!
Well said, Dr. Gil.
You DO deserve a medal.
AND, another qualification : Are we talking about primary prevention, or secondary prevention?
Solid video as usual Doc! A solid long term follow up using statins was published in the New England Journal of Medicine by Ilse and colleagues in 2019. They followed children with hypercholesterolemia who were initially randomized to statins for an additional 20 years and documented outcomes of heart disease compared to their parents. The children had notably fewer events. Below is a quote from the abstract.
"The cumulative incidence of cardiovascular events and of death from cardiovascular causes at 39 years of age was lower among the patients with familial hypercholesterolemia than among their affected parents (1% vs. 26% and 0% vs. 7%, respectively)."
So a 25% difference in occurrence of CVD events risk in the children and no death seen.
I remember reading this about 20 years ago.
It's good that you're informing people. Personally I already read this study.
Thank you! Keep doing the good work. Education is the best defense against mis/disinformation.
As always excellent information. Thank you.
Always delivers. Legend!
Great explanation. I’m on the brink of having to take stations and your videos are very helpful helping me come to grips with this.
A dose of common sense.
There are " little white lies ", " bold-faced lies", and Statistics. Thanks Dr Gil. You're the best.
Thanks Gil, for all the work you do providing us with important info & how to evaluate its meaning & worth !!
🧐Thank you for another thorough response to research results
Another factor in population that volunteer in inn taking statin is attitude. People who choose to take statins may have modified their diet also
absolutely. this is why randomized trials are important where the control group gets a placebo so all participants have the same perception
Thanks Gil
So good to find such good advice and reason on RUclips. Hippocrates would smile. Thank you!
Thank you for helping me to learn how to think critically regarding medical studies. The information can be contradictory and thus very confusing.
Great video. Easy to follow; important info presented in a clear and fairly concise manner; friendly conversational style. Thanks!
Great video, and there's also the healthspan benefits that statins could give you.
You should have a channel where you teach statistics and criticial thinking. I think maybe a medal is in order. ;-)
Yes. Of course!
Great take
I expect they help some people more than others and some of the challenge is knowing who will benefit the most.
Well I DO think you deserve a medal Gill (and crew)! How about that?? :)
Great explanation, thank you. I wonder why some studies use expected life extension, while others use hazard ratio (increase or decrease of risk during a time period). It seems hazard ratio is much more understandable.
As always great video thank you
I just wish I had started statins sooner. My uncle had a mild heart attack in his late 40's and started statins after his recovery.He died a few years ago at 98.
So what is the purpose of a study like this? Given the predictability of how social media will distort the findings, it almost seems as if the study is designed to mislead.
What about side effects? Only a small fraction are reported.
see end of video, links 2 large videos covering most of the common Qs on side effects
I’ve been doing a ketogenic diet for several years, as it works well for me. But the anti-statin messaging in the low carb social media crowd is ridiculous.
I tend to agree. It seems very reckless at times.
YES! Love it!
My greatest sadness from this video is that Gil has to reduce the description of the methodology and statistics behind his opinions.
I understand that need to keep his audience from losing their grasp.
But still, 😭
Knowledge is always limited.
Maybe they should consider using shrooms like Oysters, that contain a natural stating, lovastatin, and have high amounts of the longevity amino acid, ergothioneine.
Statin, not stating. Stupid autocorrect.
for the Legacy Effect Approach. Would scientist ever follow up with members of the control group who voluntarily decline treatment?
3:40 How do you even make a living from this, bro. You prepare like a madman for a week to post a short video, and you don't even have sponsors.
An 80yr-old lives to 80+3days instead of 80 even. A 40yr-old lives to 80 instead of 70.
Yeah….thats not how it works yo
@@wfpbwfpb It's one of the ways.
Is this really a trial or is it sensentionalist nonsense, or trolling or, maybe a social experiment in seeing how many people actually read the study rather than just following what the "findings" suggest?
8:00
💯👍😎
Does taking cyclodextrin reverse plaque?
Don't know, but some research shows Nattokinase, Berberine, Vitamin K2 and aged Garlic all helping.
I wonder why did they even do those studies , and come up with those conclusions? Are they stupid ? Or am I missing something
Go bankrupt but live on a bed demented and bedridden for 1 week.
콜레스테롤이 높아야 오래 산다는 논문이 많던데, 그렇다면 스타틴은 수명을 줄이는데 효과있는 약이라는게 더 맞지 않을까요?
Name at least one
Apart from genetic causes of very low cholesterol, a level of around 50 in blood is fine.This is the level found in young children. Every cell produces its own cholesterol, so you never can have not enough.
hi, that's covered here: ruclips.net/video/n4h135SBebc/видео.html
statins have been shown many times to prolong life in people with indication
나는 여전히 상충되는 모든 연구를 이해하려고 노력하고 있습니다! 한국의 스타틴에 대한 일반적인 견해는 무엇입니까?
huh
I wonder why did they even do those studies , and come up with those conclusions? Are they stupid ? Or am I missing something