Botulism (Clostridium Botulinum) Pathogenesis, Symptoms, Diagnosis, Treatment, Prevention
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- Опубликовано: 22 июл 2024
- Botulism | Clostridium Botulinum | Pathogenesis, Botulinum Toxin Mechanism, Types of Illness (Foodborne, Infant Botulism, etc.), Symptoms, Diagnosis, Treatment, Prevention
NOTE: This lesson was re-uploaded to correct errors found in the previous version of this lesson
Botulism is a neuroparalytic condition caused by the botulinum toxin. In this lesson we discuss what botulism is, what causes it, risk factors for getting it, the pathogenesis and mechanism of action of botulinum toxin, types of botulism illness (foodborne botulism, infant botulism, wound botulism), signs and symptoms, diagnosis, treatment and prevention.
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JJ
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JJ
You have always great videos. It's a joy to learn with you sir! Thank you very much!
detailed and amazing...Appreciative
Brilliant overview, thanks
Thank you JJ medicine that was a very crisp informative video
Very informative video, thank you so much
very comprehensive, thank you!
This video helped me so much with my botulism presentation! I was trying to figure out how to relay the pathogenesis in a less wordy way for everyone to understand, thanks a lot!
“A less wordy way”. Lol Imma buy you a thesaurus
@@RLomoterenge buy yourself a life while you’re at it babes.
Very good information, thanks
Nice, informative. Please keep on proving these wonderful videos
so a jar of lets say freeze dried food stored in an air tight container can have botulism in it?
Just found out this one!Thank you!
V.informative thanks alot
a fantastic video thanks!!
Why is there no fever response to clostridium botulinum from immune system (in foodborne cases)?
Awesome video I cane because I ferment and can and it’s always tricky making sure not to get it wrong because of this and other nasty microbe’s
What are your references? I have to make a presentation for a class and the eight or so sources I have used do not mention about 30-40% of this video. I really need your help please!
at 18:50, 120 celsius is higher than boiling temp. it is impossible to neutralize them then.
will you die just by opening an bot infected bulged can? because it will slightly pop and spread the death spores around you? how can you neutralize the bulged can?
great video !!
I just pulled a rice cooker out of storage. There is no food in it but there apears to be a film of strch in the pot. Would a deep cleaning be safe or should I throw it away?
Excellent video! we know you meant inactivated 120 degrees fahrenheit
Thank you very much
Thank you Sir!
As always, awesome
are you working in ID?
How can i get anti dote i was injected anti tetanus toxid now im suffering my body due to the injection
1:50 - So does that mean that botulism is very unlikely at home trough smelling at spoiled canned food?
I know that this might be a dumb question. But is there any way the immune system can fight off this kind of infection?
I just recovered 95% from botulism.
How did you get it ?
@@ghostedwarrior1968 don't know and the food inspectors came to my house and took a lot of my food. It's still a mystery.
How long did it take to recover?
Were the symptoms just once off or constamt until you had to seek medical asistance?
Did you get well,,,how do you test for this...
very helpful
Thanks Doctor ❤
Well done
Thank you sooo much 😄❤
i ate a banana that was black outside and on top of the inside but i ate the parts where there wasnt any black or brown and it tasted good and normal and smelled normal. am i at risk plus the banana was in the fridge for two days.
Thank u so much u help us a lot💜❤️💚💜
Can this toxicity infect to surrounding people through spraying😥?
I was thinking of doing sauerkraut at home, would you say it’s very risky? I was concerned a the botulism 😅
How can I get a PowerPoint presentation?
Super nice video
i read that you can get botulism from spoiled garlic, but by your explanation, it has to have "zero oxygen" to activate. very nice sir :)
So what I’m hearing is to not put spoiled garlic in a vacuum chamber
17:53
With my Safe Serve qualification for being a manager at a fast food restraunt. I was told that spores cannot be destroyed with high exposure to heat. What makes these spores different from the rest?
Never trust fast food restaurant qualifications on spores and bacteria. Cause majority of spores can be destroyed by heat just depends on said heat.
I had to correct my managers multiple times on how bacteria and other things work cause they get taught wrong
Also do your own research onto things. Everything is evolving in the bacteria, spores and other things so really depends what strain and stuff
article links?
Kousa medicine lena chahiye
I had this a long time ago I had a fever of 105 well spoiled turkey I was told it was good I thank I was puking and the runs at the same time 3 days later I went to the hospital could barely walk dad had to help me UC davis medical center they told me what I had
This poisoning does not happen very often, thus it is often misdiagnosed for something else. People die of breathing difficulty. Anatoxin is not readily available in hospital. When they get the anatoxin, it is often too late.
True! I cringe seeing all the Rebel Canners on TikTok using unsafe methods and canning foods that are expressly ones that you should never can at home.
Yes....I was wondering why he said the mortality rate was only 5-10% at the beginning of the video. I would think the mortality rate would be much higher.
Unless some of the strains are not as toxic and/or they took antibiotics and later discovered by lab that they had clostridia. The key then would seem to be early antibiotic treatment and then detox from the toxins.
@@medini2 cuz mortality only happens on cardiac arrest or any similarly sever to that . normally they got treated but have irreversible effect !
@@mermer58 Check out the "high meat" community...
Dziękuję
Hello. I’m on a search to find help for botulinum toxin from dysport poisoning. I got injections for cosmetic reasons and I am now struggling with central nervous system issues a host of others. Has anyone done research on how to remove the toxin after Botox injections have spread in the body accidentally from this? Pl and thank you. I’m in a group that has 25,000 ppl suffering from the toxin due to Botox..😢
This is happening to me right now from dysport and I don't know what to do. I can't even work.
There is a minor mistake in your talk. In the slide about prevention you say you need 120°C to inactivate the Botulinum Toxin. That is incorrect. the Temperature needed to inactive the TOXIN in 80°C. Cooking something at 100°C for 5 minutes and allowing all components to reach a core temperature of 80°C reliably deactivated the TOXIN. 120°C cooking can only be achieved in a pressure cooker and this kills the SPORES. Otherwise, good presentation. A- 🙂
Thanx
too good
Mistake 17:30 , I think it’s botulinum antitoxin not toxoid , toxoid is vaccination but passive immunisation is antitoxin
That's great but I was really hoping to learn more about where this bacteria comes from and how we can prevent the disease. Is heating food to 120c the only way to kill this bacteria? Are some people immune to invasion of this bacteria or is there a certain amount of this bacteria that our immune system can naturally take care of? Is this bacteria present in honey and corn syrup or do they indirectly affect the growth of this bacteria in the gut? Why is there no risk with sugar or molasses?
To my knowledge it won’t be destroyed by heat.
The spores are hard to kill, but the toxin can be destroyed, mainly by boiling food for specific amount of time.
The spores are in the soil. (Everywhere really) So all root and higher pH vegetables are suspect and should be home canned in a pressure canner at 240-250° for a specific amount of time. Garlic is known to harbor the spores. So garlic boiled in oil should be refrigerated and discarded after 2 weeks. Boiling doesnt kill the spores.
Honey may contain spores. Spores usually pass through humans without any problem but not infants. Their gut may not be developed enough. Adults with a compromised gut microbiome could allow the spores to go into the vegetative state, but its extremely rare.
For the past couple year's I've seen teens walking around with their eyes half opened looking "stoned," but i now think they are mimicking something much worse.
perfect
I'm confused. So bulging canned food means air may be present and that means C. Bot may be present but i thought it was a reduced oxygen toxin.
maybe it is Botulism can grow in a Co2 environment but not an O2 environment.... since the gas expelled from sugar consumption by either yeast or Botulism is not Oxygen it is CO2
Its gas from the metabolic action of the toxin
I was told the gas in the bulging can or jars (why you never keep the rings on your home canned goods)... is from a secondary contaminate of yeast.... which consumes any sugar and produces C02.... that was why Botulism can live in the bulging jars and cans..... home canned goods will pop their lids when there are contaminates like a yeast
Bulging canned food means spoilage. Period. There are other bacteria at work in that case, but if conditions were favorable, botulinum toxin may also be present. Under no circumstances will boiling kill all the bacteria that may be present, so dont eat it.
It’s not “air” it’s gas as a by product of decomposition and by product of bacteria etc etc
15:36 that photo just appears-
Was there a specific purpose for that? 👀
I don’t get it, do the toxins produced by the bacteria itself or its spores?
The toxin is produced by the spores when conditions are favorable.
@@mermer58 thank you so much I got it now🙏
I got Botox for migraines for the first time recently and didn't have any negative side affects so I loved it so much and it was super helpful so I made a video too just in case you or anyone else watching is interested in seeing it
Sir ji skin me becterial infection hai
Are you Canadian?
0:40 does that mean that a clostridium botulinum infected person can be cured by hyperbaric oxygen therapy?!
A hyperbaric environment would effectively kill the bacteria (since it is an obligate anaerobe), but most times, Botulism is due to ingestion of a toxin, not the bacteria itself, so hyperbaric oxygen therapy would not be effective in treating it. Hope that helps :)
JJ Medicine yeah I got it ... thank you 🙏🏻
Watched just to hear someone pronounce botulinum. Stayed for the rest
Alert and responsive that shits scary
I ate vegan pate that contains clostridium botulinum (I didn’t know until the government send out emergency warnings) I’ll see the doctor tomorrow. I feel terrified.
oh wow. are you okay?
@@ella-rn9td I’m ok now. The doctor said no problem. I’m still alive now. Thank you Ella. 🥰😂
@@blueprincesses6403 glad you're okay
@@blueprincesses6403 did anyone got botulism though?
@@ShiratoriIsOffline Thank you! Somebody died in my country because of it. The antidote takes so long to be shipped to my country.
Could anyone please tell me if this botulism can be cured completely without leaving after-effect? I’m worried about my life
Ofc, it can be cured. Use hyperbaric oxygen to kill the etiology (C.botulinum) and remove the toxin using C.botulinum toxoid (was listed into this video).
@@yosiyohanes9719 thank you very much!!!
@@blueprincesses6403 how are you doing now
@@spooonpro614 I'm totally good! Maybe the vegan pate cans I ate luckily didn't contain Botulism! I'm still alive!
@@blueprincesses6403 bruhh I thought you were diagnosed, either way good for you
How to prevent Botulism from Botox? Seems like it’s a lot more common than we thought
Easy…don’t get Botox. That’s how to prevent it.
Well guess I'm throwing away my fermented Garlic and Honey...
I ate vegan pate that contains clostridium botulinum (I didn’t know until the government give citizens emergency warning yesterday) I’ll see the doctor tomorrow. I’m scared 😟.
How did it go? I’m in similar circumstances
@@James-uw9ku I’m alive. Some people become very sick and must be hospitalized. I don’t get sick so the government tell me it’s okay, no problem.
Began what?
some people love it, get it on purpose
those damn honey garlic videos
Sir reply dijiye
🧐👍🤝
I ate 7 year out of best by date that tasted odd and fear I'm doomed thanks for the information I should have known better
im trying to figure how to infect myself with botulism. i heard someone once say “what ever doesnt kill you, makes you stronger”. so i intend on becoming superhuman by getting every bacteria and ailment known to man.thank you so much , very informative!
Dont do it man im suffering now from a medical injection of botox. Not nice
@@fm9187 what was your symptoms on your body? Did you start getting sensations on your body like pins needle all over your body and itching
Cant tell if this is satire or not 💀
@@kellymccoy8645 i had a whole range of symptoms dizzy headaches sensitive skin depersonilsation body palpitations feeling paralysed when walking state of confusion just extremely strange
@@fm9187stomach issues?
came here from watching the tea of pickle girl tiktok
King Cobra jfs brought me here
aboooout
Aboat
Heard my mom freaking out cause she just put an can that was open in the bottom into our food. She told me to look at something called botulism.
Ll