Explanation of the pathophysiology of hypercalcemia in cancer patients, and a description of common signs and symptoms. Includes a quick overview of common treatments.
I'm a pharmacy student, and I just want to say you have really helped me a great deal with my exams and rotations to see the bigger picture for a lot of these disease states. It makes drugs make so much more sense!!! Thank you for putting so much time into these videos and using your skills to help students out here learn
just a little thing, the neuromuscular symptoms of hypercalcaemia are due to what is called a negative bathmotropic effect, extracellular calcium in high concentration can block fast sodium channels and prevent the depolarization of the nerves and muscle fibres , and not related to the presynaptic voltage gated calcium channel conductance...but a great video ,, thank you
I am a PG Nurse student with a concentration in Oncology Nursing at the University of the Witwatersrand. I am preparing for my final exams and i just find your presentations very informative, stimulating and engaging. Keep up the good work Dr Wolf.
Thank you so much for taking the time to make these videos. Your explanations are amazing, please keep them coming. Your time is greatly appreciated. From a nursing student. :)
Do not change the format! The writing out is what makes your advanced pathology videos effective! There are plenty of flat slides and powerpoints out there that are NOT instructive. In fact, we all get deadly powerpoints in class, which does NOT engage the brain. You are following in the footsteps of masters like Marian Diamond who understand how to help students move information into long-term memory.
I realise this video is over 2 years old, but just in case anyone watches it, be aware than the effect of re-absorption from the GUT is through Vitamin D which is activated through an enzyme (1aHyd) which itself is activated by PTH. Secondly, HYPERcalcaemia causes a shortened QT, not a prolonged QT Otherwise great video! :)
I have hypercalcemia, not from parathyroid or medication, with horrible pain from left knee down and upper left arm bone, especially the shin bone. Lost around 30 pounds in 2 months, feel like my doctors are dragging their feet because they just don't listen. They've referred me to an endocrinologist, which is taking months.I'm afraid of how this will turn out.
I like the writing it gives you time to absorb the information your getting. But 1 question: for example multiple myolome triggers the Osteoclasts and start to 'eat up' the bone to release more calcium right!? Is that why patients can get holes and fractures in the bones?!
I'm a pharmacy student, and I just want to say you have really helped me a great deal with my exams and rotations to see the bigger picture for a lot of these disease states. It makes drugs make so much more sense!!! Thank you for putting so much time into these videos and using your skills to help students out here learn
just a little thing, the neuromuscular symptoms of hypercalcaemia are due to what is called a negative bathmotropic effect, extracellular calcium in high concentration can block fast sodium channels and prevent the depolarization of the nerves and muscle fibres , and not related to the presynaptic voltage gated calcium channel conductance...but a great video ,, thank you
Appreciate this input!
I am a PG Nurse student with a concentration in Oncology Nursing at the University of the Witwatersrand. I am preparing for my final exams and i just find your presentations very informative, stimulating and engaging. Keep up the good work Dr Wolf.
Thank you so much for taking the time to make these videos. Your explanations are amazing, please keep them coming. Your time is greatly appreciated.
From a nursing student. :)
Do not change the format! The writing out is what makes your advanced pathology videos effective! There are plenty of flat slides and powerpoints out there that are NOT instructive. In fact, we all get deadly powerpoints in class, which does NOT engage the brain. You are following in the footsteps of masters like Marian Diamond who understand how to help students move information into long-term memory.
I realise this video is over 2 years old, but just in case anyone watches it, be aware than the effect of re-absorption from the GUT is through Vitamin D which is activated through an enzyme (1aHyd) which itself is activated by PTH. Secondly, HYPERcalcaemia causes a shortened QT, not a prolonged QT
Otherwise great video! :)
Appreciate the feedback and heads up!
Thanks Andrew. Your great work is really of great benefit.
I love your videos! You have a gift for teaching,Thank you for your help:)
thank you!! great video with clear explanations and drawings - don't change a thing! so helpful for nursing school!
Thanks so much Melinda!
Thank you so much!! Your awesome!
thank you sir
very helpful
Hey andrew!, could you make a video with acute and chronic pancreatitis??
I mean i know you have a video of the pancreas but if you could be more specific on acute and chronic pancreatitis.
great work ... but you are taking long time during writting and this make it hard and long ..... thank you again :)
Calcium or potassium? You mention both in the nerve axon example...
Thanks Sarah for watching! We've passed the question along to the medical review board:)
I have hypercalcemia, not from parathyroid or medication, with horrible pain from left knee down and upper left arm bone, especially the shin bone. Lost around 30 pounds in 2 months, feel like my doctors are dragging their feet because they just don't listen. They've referred me to an endocrinologist, which is taking months.I'm afraid of how this will turn out.
Wow ur too good, thanks
Thank you!
I like the writing it gives you time to absorb the information your getting. But 1 question: for example multiple myolome triggers the Osteoclasts and start to 'eat up' the bone to release more calcium right!? Is that why patients can get holes and fractures in the bones?!
Thanks so much for your inquiry. We have passed this question on to our medical review team. Thanks again for watching!