Updated Videos! PCR Video: ruclips.net/video/8GOKaZ8MRyM/видео.html Gel Electrophoresis Video: ruclips.net/video/N3TrRc9CL9w/видео.html I drew the video while sitting in a lab supply closet and before I had a stylus... the new ones are much tidier and have better quality audio!
Thnk u sooo much #bogobiology....this explanation has no comparison.....its just so incredible.This video actually answered all the questions I had in my mind for a long time...thnk u sooo sooo much....stay blessed😁😍
#bogobiology....no need for thanks mam....this video was really worth it...also I think this video is very underrated.....like this video should get way more views than what it has got now...thnk u sooo much again mam😀😁
Thanks so much, Farah! Eventually I'll get around to cleaning up this video and making the graphics less messy; if you listen closely you can hear my students squealing in the background ; ) Sending you love and best wishes from Boston! -BOGO
Hi Zoyeb! Great, great questions! I think the best answer to whether you could run PCR on a single cell is "in theory yes, but in reality, probably not". Every cell in the body contains the chromosome bundles with a full copy of our DNA. However, some cells (like mature red blood cells) do not contain DNA, so if you got one of them you'd be out of luck. In addition, it'd be a big ask to only run PCR on the DNA from a single cell. The volume would probably be far, far too small to work with effectively. In addition, science is messy and often steps just don't work super well, especially the first time you try them. If you only had a single cell worth of DNA, you'd only have one chance to design primers that adhered with just the right amount of specificity, get the denaturing, annealing and extension temperatures exactly right (they vary depending on the ratio of G-C pairs to A-T pairs), etc etc. I'm sure there are other reasons, but the bottom line is that there's just a lot of chances for it to go wrong and you'd only have one chance. The good news is that cells are so small that even a tiny sample usually contains a lot of them. Hope this was helpful! Sending love and best wishes from Boston -BOGO
Updated Videos!
PCR Video: ruclips.net/video/8GOKaZ8MRyM/видео.html
Gel Electrophoresis Video: ruclips.net/video/N3TrRc9CL9w/видео.html
I drew the video while sitting in a lab supply closet and before I had a stylus... the new ones are much tidier and have better quality audio!
If I had a dollar for every time I understood something...
... I’d be broke
I took a course in molecular biology 9 years ago. Explains why i’m not in the industry anymore as i only understood everything now lol
Thanks, Chris! Sending love and best wishes from Boston! -BOGO
Thnk u sooo much #bogobiology....this explanation has no comparison.....its just so incredible.This video actually answered all the questions I had in my mind for a long time...thnk u sooo sooo much....stay blessed😁😍
Thanks, Maya! I'm so glad the video was helpful!
#bogobiology....no need for thanks mam....this video was really worth it...also I think this video is very underrated.....like this video should get way more views than what it has got now...thnk u sooo much again mam😀😁
wow amazing explanation!!
oh my gosh, i finally understand it now, thank you so much!!!
Thank you so much
This video made things a lot easier
Loved the way you explained it
Can we become frd
This is soo clear... thank
You!!
Glad it was helpful!
Nice explanation thank you very much Madam
Thanks, Yasam! Stay safe out there; sending love from Boston!
thank you for the citation that was really helpful
Glad it was helpful, Akira!
This. Is. Perfect.
Thanks so much, Farah! Eventually I'll get around to cleaning up this video and making the graphics less messy; if you listen closely you can hear my students squealing in the background ; )
Sending you love and best wishes from Boston! -BOGO
BOGObiology Thank youu ☺️Your videos are being much appreciated all the way from Beirut!!
thank u sm this help so muchhh
It was very helpful, thank you
My pleasure! Glad it was useful!
SIMPLY SMASHING, thanks
Thanks, Junaid! Come back any time!
thank you so much :DDD this video really helpful. keep doing it!!! :D
You're very welcome, Sindanita! Sending love from Boston! -BOGO
شكرا جدا ❤❤
thank you so much!
Top 10 unsolved crimes
THIS IS VERY CLEAR though I wished we get to know the criminal lol
Thanks, Yousif!
few small questions - can you extract the whole genome fom a single cell? and if you run pcr on it can you get multiple copies of the whole genome?
Hi Zoyeb! Great, great questions! I think the best answer to whether you could run PCR on a single cell is "in theory yes, but in reality, probably not".
Every cell in the body contains the chromosome bundles with a full copy of our DNA. However, some cells (like mature red blood cells) do not contain DNA, so if you got one of them you'd be out of luck. In addition, it'd be a big ask to only run PCR on the DNA from a single cell. The volume would probably be far, far too small to work with effectively. In addition, science is messy and often steps just don't work super well, especially the first time you try them. If you only had a single cell worth of DNA, you'd only have one chance to design primers that adhered with just the right amount of specificity, get the denaturing, annealing and extension temperatures exactly right (they vary depending on the ratio of G-C pairs to A-T pairs), etc etc. I'm sure there are other reasons, but the bottom line is that there's just a lot of chances for it to go wrong and you'd only have one chance.
The good news is that cells are so small that even a tiny sample usually contains a lot of them. Hope this was helpful! Sending love and best wishes from Boston
-BOGO
this is good
👍
Wow. Green Person? Blue Person? People are more than colors ya know.
👍🏼👍🏼👍🏼👍🏼👍🏼