ssRNA: Lyssavirus (Rabies) Replication Cycle

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  • Опубликовано: 29 мар 2020
  • ssRNA: Lyssavirus offers a detailed illustration of the known replication strategy of Lyssavirus inside an infected cell. Lyssavirus also known as Rabies causes Rabies, one of the oldest recognized infectious diseases, and is almost invariably fatal in humans and other mammals. The virus is highly neuroinvasive. It is transferred via the peripheral nervous system to the brain where replication of the virus leads to the disease. The disease is preventable through vaccination and can be treated successfully by prompt post-exposure serotherapy and vaccination.
    Written and directed by Irene Petropoulou
    Co-directed and edited by Andrew Tucker
    Main scientific advisor: Dr. Christopher Clegg.
    Chief Animator: John Bardakos
    Narrated by Marianne Graffam

Комментарии • 78

  • @brisingarinstaridavis7084
    @brisingarinstaridavis7084 3 года назад +55

    Rabies is so frightening
    I feel so sorry for anyone
    Human & animal who are unlucky enough to get infected with it

    • @RRW359
      @RRW359 2 года назад +5

      Of courseit's frightening. Excess fear is one of the symptoms.

  • @user-ft3xr7ls7d
    @user-ft3xr7ls7d 3 года назад +34

    let's erradicate rabies forever

    • @lotusflower6420
      @lotusflower6420 3 года назад +2

      Aren’t they saying Rabies will be eradicated by 2030. Let’s pray, it’s evil if you get it

    • @fatcat5817
      @fatcat5817 2 года назад +1

      Oops the cdc has it but in aerosolized form!
      So perfect!
      😌👌
      . Febru 2020 acip meeting unfinished business~

    • @teanation7800
      @teanation7800 Год назад

      It has to go, at least we had a chance of surviving smallpox! When you get rabies there’s beasicakly no chance of survival
      Edit: Basically* sorry stroked out for a second

  • @benjaminweber9301
    @benjaminweber9301 3 года назад +45

    Amazingly detailed video! This should have way more views!

    • @irenepetropoulou59
      @irenepetropoulou59  3 года назад +14

      Thank you! It was a lot of work and with the support of many experts

    • @jozefvanriet2673
      @jozefvanriet2673 2 года назад +1

      I love your take on the matter, such high hopes for intelligent and attentive life!

    • @JimmyStruthers1000
      @JimmyStruthers1000 2 года назад

      @@irenepetropoulou59 Are you Greek Ms. Petropoulou?🇬🇷🏛

  • @anandsengupta1721
    @anandsengupta1721 2 года назад +3

    Brilliantly explained with the help of the graphics. Thankyou so much.

  • @subhankardey2044
    @subhankardey2044 3 года назад +1

    Thanks Dear... for such a nice illustration..

  • @2witty4uslayer2
    @2witty4uslayer2 3 года назад +13

    This was so scientifically explain that I understood 0

  • @danielivandittopro7544
    @danielivandittopro7544 3 года назад +3

    Nice job you did great don’t give up you can still get lots of subscribers

  • @samuelknair1888
    @samuelknair1888 3 года назад +10

    Very helpful for my microbiology project for masters ❤️❤️❤️❤️❤️

  • @oksanaboiko5263
    @oksanaboiko5263 2 года назад +1

    Great Job Irene, Andrew, John, Marianneand all the team!

  • @himanshu_Chaudhary1001
    @himanshu_Chaudhary1001 Год назад +2

    we need your knowledge
    please continue sharing

  • @yaseen5372
    @yaseen5372 2 года назад +2

    Very underrated 😒 video.
    Amazing👍❤️

  • @miunya
    @miunya 2 года назад +5

    I was wondering why schools never taught me this but ireland has been rabies free for a long time but I'm glad to know incase I ever travel or just in general

  • @upscaleavenue
    @upscaleavenue 2 года назад +10

    Viruses are so amazing. I am constantly in awe.

    • @JimmyStruthers1000
      @JimmyStruthers1000 Год назад

      Viruses are terrible and they all need to be destroyed

    • @upscaleavenue
      @upscaleavenue Год назад

      @@JimmyStruthers1000 Viruses are actually integral to the ecosystems of this planet. Without them, our world would be very, very different, and not in a good way. We might not have even survived as a species.
      Phages in the ocean, for example, maintain equilibrium by culling populations of bacteria every single day.
      Viruses won't be destroyed, no matter how hard we try. We can't conquer nature. And, why would we want to?

  • @bhanuprakashr2416
    @bhanuprakashr2416 3 года назад +4

    Very nice information and understood easily

  • @sharonbenitez4345
    @sharonbenitez4345 3 года назад +3

    Very helpful!

  • @NamuraIdhunita
    @NamuraIdhunita 10 месяцев назад +1

    One of the most amazing videos on the subject I've seen!! Wonderful animation, thank you so much for all your work!

  • @user-ok2cr7gk5j
    @user-ok2cr7gk5j Год назад

    Continue please ❤

  • @saniaraj8355
    @saniaraj8355 2 года назад +2

    Very helpful❤

  • @VinhPham0708
    @VinhPham0708 2 года назад +5

    This video is really helpful!. Do you have a script? because the automatic subtitiles is not clear some parts :((. Thank you so much.

  • @ra-ge
    @ra-ge Год назад

    Incredible how these things operate

  • @lgg2304
    @lgg2304 2 года назад +3

    Wow! Uh, I think I bit off more than I could chew... but I stuck it out and finished all 12min!! 🎆🎇✨

  • @danmiller2177
    @danmiller2177 2 года назад +2

    Individuals don't really understand how dangerous the rabies viruses really are...

  • @Widderic
    @Widderic 2 года назад +2

    So are the viral messenger RNAs any different than electrical circuitry components and how they interact with the each other? My head is exploding over this stuff lol.

  • @ykl178
    @ykl178 3 года назад

    Thank You

  • @NilTheBear
    @NilTheBear 3 года назад

    Informative

  • @hxocreates4897
    @hxocreates4897 3 года назад +1

    pleas tell what the capsid of rabies virus is

  • @miz6294
    @miz6294 2 года назад +1

    Crazy complex like a computer

  • @electrowizard2658
    @electrowizard2658 2 года назад

    So nice

  • @leogelynromano3564
    @leogelynromano3564 2 года назад

    Great!!! thankyou so much for the information!! Now, I understand a lot. ♡♡♡

  • @leonidaskaragiannis7875
    @leonidaskaragiannis7875 2 года назад

    What is it?

  • @savagephoenix4979
    @savagephoenix4979 2 года назад +3

    It’s more deadly than Ebola which is why I’m here 😳

  • @KingVulpes
    @KingVulpes Год назад +3

    Takes one mutation to screw us all over

  • @igo7434
    @igo7434 2 года назад +2

    Thanks for this video. Very informative! Worse way to go if you get rabies.

    • @Zebraaaaaaa668
      @Zebraaaaaaa668 Год назад

      How long do rabies survive in land under sunlight?

  • @vikasbiliye5023
    @vikasbiliye5023 Год назад +1

    Given that we have such detailed information, cant we maybe hack this virus system and make it dysfunctional forever?

  • @prettyprudent5779
    @prettyprudent5779 2 года назад +5

    Be wary of wild animals, folks. Wear protection when you go out, like a sharp item or pepper spray.

  • @leifdux7277
    @leifdux7277 Год назад

    They look like the hair rolls to curl your hair.

  • @jericho4298
    @jericho4298 Год назад +1

    Whoa! This is very informative. Imagine you are being assassinated using a small gun that shoots a very small dart that is filled with rabies (you wouldn't even notice it) then 1 week later... POOF!

  • @weiner_hands-guy914
    @weiner_hands-guy914 2 года назад +1

    I really can't follow this video completely. Too scientific for me and I don't understand a lot of the terms. I'm definitely not ready for this content yet.

  • @up67bloge
    @up67bloge Год назад

    We had got the dog vaccinated 9 months ago, after 9 months of getting the full course, I touched it again, so I went and got the full course done.
    Looks like I had to get only two waxing done Sharif

  • @ROT8TED
    @ROT8TED 2 года назад

    Got so lucky recently with hematoma instead of puncture trying to feed racoon, lesson learned...dumb me...

  • @phycopath2122
    @phycopath2122 Год назад

    pov you fall asleep first at the sleepover

  • @fatcat5817
    @fatcat5817 2 года назад +1

    I am soo happy the Cdc has aerosolized lyssavirus!
    I wonder if they will sell it to little old me? 😳
    Feb 2020 acip meeting unfinished business. 😍

  • @dnap2526
    @dnap2526 2 года назад +2

    But after it infects the cells what does it do exactly

    • @JohnnxxKing
      @JohnnxxKing 2 года назад +1

      Well u get to madness and suffer from breathing and ur eye goes insane and u cant even control it it moves it own when it on final stage
      Its almost like zombie apocalypse if this disease keeps going

    • @raypunn
      @raypunn Год назад

      ​@@JohnnxxKing but why

    • @Pikachu-xz9gb
      @Pikachu-xz9gb 8 месяцев назад

      @@raypunn fok u that's why.

    • @TheWagonroast
      @TheWagonroast 3 месяца назад

      ⁠@@raypunnIt begins to take over your brain, which causes less control over yourself, and causes aggression, the inability to breathe well, etc because of dead/malfunctioning brain cells

    • @raypunn
      @raypunn 3 месяца назад

      @@TheWagonroast i mean what are the exact chemical reactions that cause it to control nerve cells in that way

  • @wiki5566
    @wiki5566 2 года назад

    Are you there? Alive?

  • @dnap2526
    @dnap2526 2 года назад +3

    How did they figure this stuff out?

    • @A.K.00
      @A.K.00 2 года назад +4

      That is what science and research is all about

    • @noobnesz
      @noobnesz Год назад +1

      Petri dishes, microscopes, and a whole lot of time.

  • @goksenincakr2466
    @goksenincakr2466 3 года назад +3

    05:32 Gucci Gang :D

  • @headrush2190
    @headrush2190 3 года назад

    based

  • @salvadorhirth2919
    @salvadorhirth2919 Год назад +1

    If the genome of rabies viruses do contain one or more palindromic sequences, (I believe that such sequence probably exists), at least three bases upstream and downstream from the core of the palindromic sequence and one species of bacteria certainly produces a restriction enzyme that recognizes and cleaves said palindromic sequence. Then, hopefully, a novel class of antiviral therapy will be created if the target cells can be transfected with a gene encoding the restriction enzyme.

  • @pzyxn2745
    @pzyxn2745 3 года назад +1

    Amogus

  • @TylerDWard
    @TylerDWard 3 года назад +1

    Why did I think I was watching SARS-COV2...maybe there's similarities

    • @A.K.00
      @A.K.00 2 года назад

      That they are all viruses?

    • @themaestro3034
      @themaestro3034 2 года назад

      This is how RNA viruses work on all cells.

  • @bobibakar
    @bobibakar 2 года назад

    All is lie, nothing work is done to get clear virus operation activity.

    • @A.K.00
      @A.K.00 2 года назад

      Really? Then you do it

  • @rajeibanvijeyakumar8471
    @rajeibanvijeyakumar8471 7 месяцев назад

    im the 300 subscriber. thank me later.

  • @trainmakerofficial
    @trainmakerofficial Год назад

    T-pose