Hello! I'm a pediatrician in practice, not actually studying for a test, just reviewing, in this case, vitamin B12 deficiency. I needed to find a concise but clear explanation of the Schilling test, which I remember in a muddled way from medical school. This was elegantly done and very helpful! I periodically review basic science, because so much is always changing, so I will be looking for more of your videos. Great work!
You would give Intramuscular B12 only in the beginning since it takes years for B12 to be depleted from you body, therefore B12 receptors are going to be fully saturated after the first injection and there is no need for more B12 injection.
Yes you are correct! Since vitamin B12 takes years to be depleted from your body, all the B12 receptors will remain saturated after the 1st IM unlabeled vitamin B12. There is no need to give another IM vitamin B12.
Oh my gosh dude. Thanks so much!!! Your video was a big help. Made everything so clear for me and helped me tie things together! Cant wait to see your other videos!
This was an Awesome Video! this explanation was so explicit, i think i will be able to explain to the class tomorrow precisely how the schilling test works..Thank you.
This really is such a simple test though. Give the body what it may be lacking in absorbing the vitamin. If there's an increase it's the part of the body that produces those things that is the cause.
B12 is only absorbed at the terminal ilium, so any pathological event such as Crohn's disease is going to prevent its absorption at the terminal Ilium causing B12 deficiency.
+Joseph Arévalo, We're glad you found this video tutorial helpful. Please check out our other videos as well and feel free to share them with others :)
I have tension/hangover like headaches everyday for a year and a half now. I've seen multiple doctors (and specialist) with no answers; 1)should I request a Shilling test? 2) Why do doctors prescribe meds without testing? 3) will I ever get better :(
does increase or decrease refer to urine or serum? why would you see increased excretion in urine if you give labeled B12+ IF to someone with pernicious anemia?
Hi! This is great but i'm confused about step 2. Do you assume that you liver is still saturated. So then if it is high in the urines it means that the problem is a lack of intrinsic factors. If it's low in the urines it means that we go for step 3. I'm just confused because I'm not sure we assume that the liver is saturated. If it's not I really don't get it.
Hi i have a question from my exam. Pernicious anemia patient has an order of schilling test, 24hrs urine collection. The doctor ordered urinalysis, wat shud you do? a. collect urine in urinary catheter b. get urine sample in the 24hr urine collection bottle c.wait until you finished the 24hr urine collection to get the urine sample
More Simply .... 1- give B12 intramuscular ... so now transcopalamine ( B12 carrier ) is blocked if u give more B12 will not bind 2- give radioactive labelled B12 orally ...normal person secrets more than 25% in urine over 24 hours 3- if there is a defect is secretion >>repeat the test after giving intrinsic factor .. if improved = intrinsic factor deficiency if not there is no response = small intst. disease hope to be helpful :)
Hello! I'm a pediatrician in practice, not actually studying for a test, just reviewing, in this case, vitamin B12 deficiency. I needed to find a concise but clear explanation of the Schilling test, which I remember in a muddled way from medical school. This was elegantly done and very helpful! I periodically review basic science, because so much is always changing, so I will be looking for more of your videos. Great work!
Hi,
Thank you for your kind words! I'm very glad this was helpful to you :)
makes so much more sense now, with the diagnostic approach
I'm glad this was helpful to you! Good luck on step 1 :)
Enjoyed your clear and concise explanation of my husband's test....and understand it better!Mrs. Robert F.Schilling
This is hilarious
Thank you, very easy to understand, even for a patient.
thank you boss.. you made it very simple.. Would appreciate if you could put a powerpoint presentation which we could download as well.
its literally the end of the academic year, and im understanding this now, thanks to ur video....... great work sir!
Great lecture - helped me a lot!
You would give Intramuscular B12 only in the beginning since it takes years for B12 to be depleted from you body, therefore B12 receptors are going to be fully saturated after the first injection and there is no need for more B12 injection.
Yes you are correct! Since vitamin B12 takes years to be depleted from your body, all the B12 receptors will remain saturated after the 1st IM unlabeled vitamin B12. There is no need to give another IM vitamin B12.
great video, i wish my past teachers could have made it look this easy
Thank you very much. Glad it was helpful to you.
All the best
You're Welcome! I'm glad it did
Oh my gosh dude. Thanks so much!!! Your video was a big help. Made everything so clear for me and helped me tie things together! Cant wait to see your other videos!
This was an Awesome Video!
this explanation was so explicit, i think i will be able to explain to the class tomorrow precisely how the schilling test works..Thank you.
This really is such a simple test though. Give the body what it may be lacking in absorbing the vitamin. If there's an increase it's the part of the body that produces those things that is the cause.
Thank you so much for such thorough explanation. It was helpful indeed. If get a question on the step 1 on this concept, you get the credit!
Thank you so much........very well elaborated
Excellent, thanks from Dominican Republic!
Great thank you so much! i always had a difficult time understanding this till now.
This is very helpful for my review. Thank you for the explanation in a simplified way.😊
B12 is only absorbed at the terminal ilium, so any pathological event such as Crohn's disease is going to prevent its absorption at the terminal Ilium causing B12 deficiency.
thank you for this video!! immediately made more sense!
Great Video, it was very helpful!!!
+Joseph Arévalo, We're glad you found this video tutorial helpful. Please check out our other videos as well and feel free to share them with others :)
Thanks from Brazil.. very helpful
U explained so nicely .Ty
thanx it helped me understand better!
Thanks, such a great, clear explanation!!
Thank you, your lecture is awesome.
I have tension/hangover like headaches everyday for a year and a half now. I've seen multiple doctors (and specialist) with no answers; 1)should I request a Shilling test? 2) Why do doctors prescribe meds without testing? 3) will I ever get better :(
Thanku so much for the video❤
well explained, great job!
do you give an IM b12 shot with each step?
It seems like you would have to to make sure that the radiolabled b12 ends up in the urine
Great video, thanks!
thanks, great explanation!!
Thanks for the informative video! Is dicopac test same as schiling test and is it a conclusive test for B12 malabsorption/ pernicious anemia?
great video!!, it help me a lot
Best video...
Thank you
Wow nice video
It s really good tnx
Thank you for this!
thanks
Thanks, really helped me!
what happens if the salivary glands are blocked/deficient causing dry mouth and the R factor doesn't bind with the B-12 in the first place?
That makes sense, thanks a lot!!
Thank you very much!
if the pancreatic enzyme test comes back low, would you then do endoscopy of the duodenum?
Thank u so much for this video
are you giving intramuscular b12 during each step in order to saturate receptors each time and allow for excretion?
does increase or decrease refer to urine or serum? why would you see increased excretion in urine if you give labeled B12+ IF to someone with pernicious anemia?
Thankyou somch for ths video😭
thank's that was vary helpfull*****thank's
you have really nice writing. lol. big thanks for the video from a nclex studier! :)
it saturates cobalamin or "receptors'?...small details
Thank you..
Thank u
thank you very much
would B12 methylcobalamine Sublingual tablets be the best way to address a deficiency without doing the Schilling test?
Hi! This is great but i'm confused about step 2. Do you assume that you liver is still saturated. So then if it is high in the urines it means that the problem is a lack of intrinsic factors. If it's low in the urines it means that we go for step 3. I'm just confused because I'm not sure we assume that the liver is saturated. If it's not I really don't get it.
very nice video
exelente gracias
thank you
Hi i have a question from my exam.
Pernicious anemia patient has an order of schilling test, 24hrs urine collection. The doctor ordered urinalysis, wat shud you do?
a. collect urine in urinary catheter
b. get urine sample in the 24hr urine collection bottle
c.wait until you finished the 24hr urine collection to get the urine sample
More Simply ....
1- give B12 intramuscular ... so now transcopalamine ( B12 carrier ) is blocked if u give more B12 will not bind
2- give radioactive labelled B12 orally ...normal person secrets more than 25% in urine over 24 hours
3- if there is a defect is secretion >>repeat the test after giving intrinsic factor .. if improved = intrinsic factor deficiency if not there is no response = small intst. disease
hope to be helpful :)
Excretes 25% of B12 in only 24hrs? That’s not true, I have an overload of B12 would be good if this was true but u said is completely false
Thanks a lot. Finally I got it ;)
could type 1 and or type 2 diabetes contribute to a b12 deficiency related to pancreatic deficiency
do we still use this test?
Tx nice video
8 years later... writing so small. Walmart sells a large board $17.00.
helpfulllll
genio !
Is getting fat?
💖
Thank you!
Thank u
Thank you!