6000 mgs daily are you saying? they say taking to much of it can cause damage to the body. what i hear on other channels. though I guess i have no clue 10,000 mgs or 10 grams a day is high
I take 1 gram of taurine most days and even though I am quite overweight, an ultrasound of my organs showed no fatty liver etc. I believe that my combo of l-taurine and milkthistle helped me.
@@trafficjon400 I know that higher dosages in women especially can have bad effects. I took 2 grams one day instead of 1 gram and boy did I regret that. I felt like I was going to have a heart attack, racing pulse and quite worried. I do not have any problem taking 1 gram several times a day though but NOT too much in one sitting.
Let me take a stab at summing up the situation with taurine. Taurine is amazing, and without question one of the most promising things being researched right now in the longevity space. All indications also point to it being safe. It seems increasingly clear that you'll want this in your life each and every day. If you can get enough from your diet, perfect. Most people don't, so for the vast majority of folks you're going to want to supplement. It's cheap to do so. Start as soon as you can, and if you're over 30, start right now. There you go. Go be healthy.
@@gordo3582 I would encourage people to do their own research about this, but I have seen suggestions to aim for a gram for every decade of life. For instance, for somebody like me in their mid-40s, I am taking 4.5 grams a day. If you were 50, you would take 5 grams, and so on.
I eat chicken heart in alternate days, it's full of nutrients, vitamins and minerals, plus a lot of taurine... 100g of chicken heart has 300mg of taurine.
I've started making my own supplement drink. Vitamin C, Glycine, NAC, Glutamine, Taurine. Buying the powders and adding a small ~3g scoop of each. If I find some nutrient that shows health benefits, it gets added to the mix.
@@pablofarias8902 It's an amino acid, and should be as stable as all others of those are. I'm using a taurine powder and it shows no sign of degradation for as long as 1/2 kg lasts. I mix it in a whey protein and a few other things: o Hydrolyzed collagen o Glycine o. Creatine Unsweetened natural whey, because glycine is a sweetener. I use half of that and half of Turkish or Greek yogurt at my breakfast, because those yogurt are 10% fat, and too little protein. And we need more protein at breakfast! Blueberries(eg bilberries) and raspberries, and my breakfast is almost complete.
I train jiujitsu and weight train nearly everyday. My pre workout before each is 6g taurine and 9g of l-citruline malate and it has a significant positive effect on my performance.
Taurine, Creatine, Glycine and NAD are helping me with HIT hypertrophy twice a week and HIIT sprints and bike sprints, twice a week. I am 59 and getting stronger, slightly heavier, more muscular and faster. I also walk 2-3 miles a dog with my training partner.....a yellow lab mix 🐕
FYI ~ might be worth a trial of adding acetyl-l-carnitine (or carnitine, but there are additional benefits with the acetyl group) prior to HIIT. It helps shuttle fatty acids into mitochondria for ATP production. I also find CoQ10 helpful personally taking NOW's 400 mg.
problem is - most people are deficient in taurine and glycine nowadays. So taking it is pretty much mandatory. + taurin has very good calm effect - mild anxiety almost non existent after 2g
Taurine was life changing when I started taking it. My sleep was comparable to when I was a child. Every morning I felt deep rejuvenation. And I only took 2-3 grams before sleep. That lasted for about a year. It started to make me wake up to pee 2-3x/night and I often woke up feeling hot. Something must have changed in my chemistry. Nowadays I seldom take it. My sleep stack is different but has similar effects.
You might be b12 deficient. Especially if you take supplements like glycine and nac which might deplete methyl donors and in consequence can lead to b12 (methylfolate) deficiency. The symptoms you listed can be caused by b12 deficiency.
Taurine is known to suppress sympatethic nervous sytem activity. Maybe is messing with your bladder. I was thinking to try it because I suffer from chronic pelvic pain and bladder hyperactivity. That's bad news for me...
@@an.20.24 I definitively need to pee a lot on morning when I wake up when I take 2g of taurine for a week. Also it is known to give you liquid poop past 2g a day
Siim, In terms of pharmacological effects of Taurine, the results can not be achieved with food sources as the there are competing amino acids and extraction of the taurine through food does not achieve clinically significant levels. This is how GLY/NAC works as well. Comprised functions in aging exasperate this. Isolating the amino acids have pharmalogical effects, food sources do not.
Thank you for the the very quick and detailed overview. The only think I would like to add is that while the effect on the lifespan may not exactly translate to humans, there exist no other supplement that has such a large effect on mice, so it could be good starting point. Regarding dosage, taurine levels drop significantly with age, and those statistics include part of the population that consumes taurine-rich foods. So it is reasonable to assume that dosage should depend on age.
Nice, but why don't you measure your taurine blood level? I did that (took a amino acids blood test) and the only amino acid that was below reference limit was taurine. Therefore I supplement with 3 grams tsurine powder and plan to retest soon.
I've been taking supplements since 1987, after having thyroid surgery, trying to regain some balance to my energy and focuy. I've tried everything, from Arginine to Zinc, which happens to be two of the first supplements that grabbed my attention, and showed some promise, but would fall short of a consistent improvement. I've tried Hartshorn for the heart, Milk thistle for the liver, Ginkgo for the brain, and Cayenne for circulation. I've even taken digestive enzymes, with bile salts, to help with digestion. Now I'm hearing about this, not so mysterious nutrient, that was added to cat food and Red bull, and had a supporting role in some workout supplements, that seems to play a significant role in all these areas of metabolism. I started taking it sporadically, some years ago, because it had something to do with calcium regulation, which was an issue, with my messed up parathyroids, which control calcium levels. But I never took it really seriously, thinking it was a miner player. Apparently I was wrong. It's only been a few weeks, but it's showing some improvement in some of the areas that its said to influence, like energy, anxiety,, and general cognition .😌✌🏼✨
It makes my muscles much much less sore from exercise combined with magnesium and B6 in P5P form only. I have a chronically too low LDH level (a rare genetic disorder likely), which causes my muscles to get extremely sore if I in any way overexercise. DMG (the only glycine form I can take without adverse effects) does the same for my body.
I liked and subscribed! I’m 32 and am now getting into longevity. I’ve been following Bryan Johnson’s protocol for about a year now but am happy to see others experimenting with supplements as well. Also, congrats on your high ranking on the rejuvenation Olympics board!
@@NateB Probably because he gets the most publicity of anyone in the longevity world. SIIM is great but he is also young so some of the things he does or does NOT do aren't applicable to older people (for example about certain supplements he has said: "I'll start taking it when I'm over 40").
I add it to my green tea in powder form. It has no discernible taste and dissolves easily. I’m older, physically active, insulin resistant and don’t eat seafood every day, so I’m in a category where it could help.
Absolutely loved this deep dive into taurine's longevity benefits! 🐾 It's fascinating how a simple amino acid can pack such a punch in the anti-aging arena. Who knew that something so small could potentially add years to our lives? The studies you mentioned really highlight taurine's role in metabolic health-it's like the unsung hero of the supplement world! And let’s be honest, if taurine can help us dodge the aging bullet while keeping our blood sugar in check, it might just be the fountain of youth in a bottle. Also, I can't help but chuckle at the thought of mice living their best lives with a 25% lifespan extension-talk about a rodent retirement plan! 🐭💼 Looking forward to your new book, *The Longevity Leap*! If it’s half as enlightening as this video, I might just need to stock up on taurine to keep up with all the wisdom! Keep up the great work, Siim! 🌟
Taurine is interesting. But we don't know much about how it works in the body. This is an idea, from a research article in Nature: "The hypothesis of taurine as mitochondrial matrix buffer The mitochondrial matrix as biochemical reaction chamber Stabilising the pH gradient by the presence of a buffer compound like taurine in the mitochondrial matrix transforms the matrix into a biochemical reaction chamber with a slightly alkaline pH 8.0-8.5. It is well established that several important biochemical processes occur inside the mitochondrial matrix, e.g., all the reactions in the citric acid cycle, fatty acid oxidation and some of the reactions in the urea cycle." We also know that cats can't produce taurine and have to get it from their food. If they don't get it, they get blind and have heart failure. We humans creates enough of it not to show any disease, but probably not enough for optimal health. If taurine works by creating a good osmotic environment in multicellular animals, it explains why it's so hard to understand it's effect. It's pretty indirect! It's an amino acid, but not a building block of our proteins like other amino acids. That it's produced in animals shows it's needed. But what's it's optimal level?
I started taking the recommended dose. 500mg. I now take 2000mg per . I feel terrific and think you should increase the dosage. Increases stamina and endurance
@@DinoFancellu I'm trying decaffeinated coffee with creatine, since it dissolves well and masks the taste well. I have not actually tried the taste of taurine since I have only taken that in pill form, but adding it to coffee sounds interesting. I usually do the coffee in weekends, when my breakfast is eggs, which are hard to combine with creatine because they solidify before getting warm enough to dissolve it.
@@DinoFancellu me too! take high doses glycine too and Im wondering how to get all the stuff into my daughter.... I was even vegan when she was born! And I had a lot of deficiencies in my body its insane!
If you have the MTHFR gene mutation, then there's a risk the homocystein level gets too high, which can lead to many diseases from cancer, to cardiovascular diseases, to Parkinson's, sclerosis, schizophrenia, diabetes etc Taurine lowers the critical homocysteine level.
I have had my homocystein level measured, and it was too low but I do also take high dosage B12 and methylfolate. Can't say what it was like before that. Only started taking taurine after I had it measured. Hope, it has not made it even lower?
He was praising it the whole way through. He doesn't take it because he get's a lot of it from his food. The title is designed to make you click, which I agree that is annoying. Also it's misleading because the point of the video was NOT "why he is not taking it".
A supplement being amazing and me taking it don't have to be mutually inclusive. There are dozens of amazing supplements out there. Do I have to start taking all of them?
Yes, maybe! But the level goes down when older, as he showed in the video. Probably because the body produces less of it (from other amino acids). He will need more of taurine from the next decade.
@@NateB some people take a few grams before bed. I just take my 8-9g with meals throughout the day and then 1g before bed. It’s all been positives. Zero side effects for me unless I take 3+ grams at once, I notice a bit of a lack of drive to do things which is fine later in the day
I started taurine one month ago. Since I use a kinesiology doctor, I was tested and told to use 2,000 mg. daily on an empty stomach. I am taking it for a specific reason. To date I can tell NO DIFFERENCE. So, I researched to see just HOW LONG it will take to get into my system, so that I CAN know that it is BEGINNING to work. I was thinking maybe several MONTHS. Yet, my answer totally shocked me. I read that I would be able to tell a difference…….within ONE HOUR. ONE HOUR. I am frustrated and disgusted and frankly am ready to toss it. What do you have to say, please ? PLEASE ? Thank you. Today is 8-8-2024.
@@lnsuvasquez2466 THANK YOU ! ( I had 4 new bottles of the Taurine come in yesterday. Try my best to stay stocked up on all vitamins and supplements. ). Appreciate your advice.❤️
Dont care about longetivity of taurin, I take it for sports, u can also take in powder form like a protein shake, no need to swallow these big capsules
I take taurine since 2 years and i may not have gained muscle mass a lot but my i feel performance boost, no sure it has a direct corelation with taurine or not but i choose to continue taking it.
I don't really like how there's so much focus on longevity nowadays. Everyone wants to live longer, ofc, but quality of life matters a lot too. Taurine has many other benefits that aren't related to longevity per se
I agree, personally a little weary of hearing very young people touting the benefits of select natural vitamins, snake oil and remedies for all sorts of things they have never encountered. Here comes the longevity craze...they can only speak to the theories and studies, of MICE. I want to hear it from a 120 year old, a baby face just does not lend credibility! LOL Regardless, we'll likely outlive the weirdo self righteous vegan types anyway, and enjoy life too!
Really Siim . Show me ONE jap. Person that is 150yo. 😢. YOUR WRONG ❤. Ai will soon take the guess work out of it and all gurus and snake oil salesmen will soon be gone.
I would be cautious it was recently linked to tumor growth in energy drinks .. after I took I had benign tumor on my kidney, so I'm scared of taurine now
@@stephenfidler1005 I never drank energy drinks in my case , however I'm talking about that research ... It may not directly cause a tumor however it may grow one ? We need more research. Often these days people ignore facts they are passionate about something they take unfortunately. Also research has become biased
@@theancientsancients1769 hah! energy drinks are the problem! its the sugar and sugar shall not be mixed with coffin and amino acids like taurine. drink water and put taurine in your daily smoothie/ shake, Ive taken taurine for 4 years after my psychosis and its the best thing. I even feel it the days Im not taking it! so taurine, glycine, nmn, coq10, b complex, d3/k2, a superb multivitamin, adaptogens, I look younger and younger every day its insane!
Im a postman , i am 62 and quite fit , but recently because im on a hilly area i am slowly lagging i feel lactose in my muscles at some of the steep walks. Ive been on 3 tablets each morning and its a game changer , i have gone from 12 stone 12 to 12 stone 6 but the real change is my energy levels on this supplement , its taken me back ten years and i only pay £9.99 a month for a bottle of the supplement. my wife has ms and i have her on 2 of these a day as well . Its a game changer for me i am in a better shape than ten years ago . There is no catch , these taurine supplements are harmless try them for a month ,i tried them for a month first at 2 a day but really you need the three , please watch the videos and others about taurine it is a natural thing not like steriods . And like i said Only £9.99 for a months worth so no money making con .
Bryan Johnson spends $2M/yr on doctors supervision and optimizing longevity. His longevity ratio is 0.72. Are you saying all he has to do is take taurine and he can reach .75?
I take taurine, magnesium and creatine blended into low carb blueberry smoothies.... I also blend larger batches and potion then out 2-3 days in advance. Do you think there's any issue with these supplements being blended into a smoothie and sitting for 2-3 beats before consumption? They don't denature or anything do they?
Creatine loses its effectiveness as it sits. Old advice was to drink it within ten minutes of adding to liquids but now I think it can be extended to within an hour, but probably not good to wait a few days.
Anyone knows if taurine increases prolactin in men? I've seen this info circling in the biohacking community and there seems there's no consensus on that...
You seem to be aging well beyond your age... Perhaps it's the muscle/weight loss you mentioned in the vo2 max video (?) but it's quite apparent, at least to me and my wife. I know it's unsolicited feedback but I thought it might give you some food for thought given your anti - aging interests and the fact that people are generally not great noticing this kind of changes in themselves. Cheers.
@@SiimLand I think a "drier" face looks older. It's giving that tired middle aged man look. I kind of went in a similar direction after my cut from 92kgs to 77kgs and ending at about 9-10% bf. It wasn't as bad per my wife but it started to show apparently. I didn't lose strength which you mentioned in your video, though.
I'm 43. It definitely increases exercise performance. The effect is subtle, similar to taking creatine. I take 1g a day. On days I'm playing sports, I'll take 4g that day.
The title of the video seems click-baity and misleading given the conclusion. As you implicitly acknowledge yourself: there seems to be no downside to supplementing taurine other than the cost, and potentially quite a lot of upside. One "use case" you didn't mention is to counter taurine deficiency which is common in older humans. The older you get, the more sense it makes to supplement. The quantity you supplement should probably gradually increase in old age, too. Supplementation seems the winner when compared to eating lots of tuna, since tuna and other fish often contain more heavy metals than you'd want to ingest. Not sure about bivalves and seaweeds. And obviously, this isn't just a dietary matter. Killing sentient fish so you can get your pRoTeiN and taurine seems like a poor ethical choice. By buying wild-caught fish you also support the industry responsible for 50% of plastics in the oceans, almost all of which comes in the form of nets. Those are the nets that seals and dolphins get caught up and drown in. 5-6 capsules of 1g of taurine daily doesn't seem so awful either. You can spread them out over each day. So... maybe you should re-write your take ("Why I'm not taking it")?
Hi, thanks for the feedback. In my videos I differentiate between what I personally do and take versus what I think is effective and has evidence. Taurine has evidence that it works in a certain population and like I said the clinical trials are done on people with poor metabolic health. A lot of people fall under that umbrella. I don't, which is why there's less expected gains for me from taurine. Maybe it'll change in the future, but for now it's not my priority.
Taurine 6g basically reset my satiety control. I took it with whey protein while exercising 5-7h per week and with BMI 28-9. It lead to huge BMI reduction in a few months. Not sure about the mechanisms though.
@@User98681 My initial theory was that taurine simply worked by decreasing appetite and therefore changing energy balance. Yet there seems to be a noticeable increase in fat oxidation as well which may explain some of the effect on weight, too: ”fat oxidation increased by 40% with 6 g of taurine (p < 0.05), suggesting that a higher dose was necessary to stimulate lipid metabolism. Furthermore, a decrease of 4% was observed in the respiratory quotient when compared to the placebo group, suggesting a relative intensification in lipid and beta-oxidation [54]. Moreover, our results showed a glycerol threshold of around 0.40 µm/dL for both TAU supplementation doses, making it evident that the increase in glycerol levels was an effect promoted by the exercise session; however, this was in association with the results of the lipid oxidation, which were superior to the placebo. Thus, our data indicate that taurine promoted an additional effect on lipid oxidation.”
@@Neonomide good to know. I’m on day 2 6 g taurine 15 g glycine. Noticed results with my anxiety the first day. MAJOR reduction. Also been doing carnivore for 3.5 months now.
If it were beneficial to take taurine, then why isn't there stronger evidence for taking it? There is money to be made so if they can prove it they would.
Probably because humans create enough taurine, at least when young, to not show any deficency. We probably need more of it from food. But if we don't get enough of it, we blame our frailty on old age. It's of course not just lack of taurine, but many other things too that makes us not age well. Taurine hasn't been researched enough to know how it works. That makes it difficult to find out how much we need.
No, it's just as heat insensitive as other amino acids are. Taking it in a hot beverage is OK, if that's how you like it. I don't heat it, though, because there's no reason to do that.
I tried Taurine back in 2020. The result was not good. The result was heart palpitations. I never took it again after that experience. I do not recommend it because the side effects exist and are not well documented.
I take taurine along with l-arginine to inhibit my exercise induced supra ventricular tachycardia, which I found support for in a study. For me it reduces the risk of arrhythmia.
I recommend to drink Monster sugar free energy drinks.. each 500 ml can contains 1000mg of Taurine, 80 mg caffeine, guarana, L-cartein and panax ginseng extract. Costing only 1-2 € depending of the country. Comes much cheaper than supplement jars..
Why would this video and the person speaking rule out taking touring just based on a few rat studies and metabolic health when touring has dozens of other directly positive ameliorative effects....????
If you are getting most of your taurine from fish, I'm afraid thats bad news in terms of microplastics. I would eat grass fed meat instead and supplement krill Omega 3 and Taurine to avoid the high microplastic content.
Additionally, most fish are farmed and the wild fish are being rapidly depleted. Grass-fed beef is more sustainable. I pursue the same strategy- supplement with 4 grams of omega 3 and take 6 grams a day of taurine a day.
From the various studies I've seen, seafood and grains and root vegetables are the worst categories. From this I would infer that grain fed meat is worse than grass fed meat. Grain fed meat may well be as bad or worse than seafood. Of course there is also a complex bioaccumulation effect with fish (just like with avoiding mercury) so the lower down the food chain the fish is the better.. i.e. whitebait, anchovies better option than tuna, cod, etc.
@@ainahaganot really - lots of people take this much - the goal is to increase your Omega 3 index to the optimal level, which is 12% of your blood cells. I am at 8 now. If I hit 12, I will ratchet down my intake.
I took taurine for about two months- didn’t feel much, no effect on sleep or exercise performance…maybe a tiny positive recovery effect? Couldn’t take more than 3 grams per day without experiencing diarrhea.
I don't know the exact weight ratio but they are chemically bound in 1:1 molecular ratio, and 3..6 g of magnesium would be off the scale. It should work great but only provide a small dose, you would need to get the rest of the taurine elsewhere.
![Taurine: The Nutrient of Youth [Science Explained]](http://i.ytimg.com/vi/qH5QumHGrgk/mqdefault.jpg)
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taking 3 grams taurine for 14 years. Prescribed along with HRT for anti aging. it cleared my gallbladder of sludge. it works
14;years is a lot, you might need higher dosage as you've gotten older.
6000 mgs daily are you saying? they say taking to much of it can cause damage to the body. what i hear on other channels. though I guess i have no clue 10,000 mgs or 10 grams a day is high
I take 1 gram of taurine most days and even though I am quite overweight, an ultrasound of my organs showed no fatty liver etc. I believe that my combo of l-taurine and milkthistle helped me.
@@trafficjon400 I know that higher dosages in women especially can have bad effects. I took 2 grams one day instead of 1 gram and boy did I regret that. I felt like I was going to have a heart attack, racing pulse and quite worried. I do not have any problem taking 1 gram several times a day though but NOT too much in one sitting.
@@mettejensen8653 Me too but a 1/2 pound of medium rare steak will over ride the taurine
Let me take a stab at summing up the situation with taurine.
Taurine is amazing, and without question one of the most promising things being researched right now in the longevity space. All indications also point to it being safe.
It seems increasingly clear that you'll want this in your life each and every day. If you can get enough from your diet, perfect. Most people don't, so for the vast majority of folks you're going to want to supplement. It's cheap to do so. Start as soon as you can, and if you're over 30, start right now.
There you go. Go be healthy.
Very well said❤
Only thing to add is recommended dosage, 3 to 6g per day.
@@gordo3582 I would encourage people to do their own research about this, but I have seen suggestions to aim for a gram for every decade of life. For instance, for somebody like me in their mid-40s, I am taking 4.5 grams a day. If you were 50, you would take 5 grams, and so on.
I eat chicken heart in alternate days, it's full of nutrients, vitamins and minerals, plus a lot of taurine... 100g of chicken heart has 300mg of taurine.
Yeah if you don't mind the massive increase in Cardio vascular disease.
I've started making my own supplement drink. Vitamin C, Glycine, NAC, Glutamine, Taurine. Buying the powders and adding a small ~3g scoop of each. If I find some nutrient that shows health benefits, it gets added to the mix.
I take Taurin since years every day but never use capsuled. The Powder is cheap enough to buy in bulk.. 2,5 Kg for 40 Euros should make a good Job😊
It's cheaper for sure
yes, I take 1kg bags.
Does it preserve well and keeps its properties?
@@pablofarias8902 for sure no problems with the powders. Just my own experience
@@pablofarias8902
It's an amino acid, and should be as stable as all others of those are.
I'm using a taurine powder and it shows no sign of degradation for as long as 1/2 kg lasts.
I mix it in a whey protein and a few other things:
o Hydrolyzed collagen
o Glycine
o. Creatine
Unsweetened natural whey, because glycine is a sweetener.
I use half of that and half of Turkish or Greek yogurt at my breakfast, because those yogurt are 10% fat, and too little protein. And we need more protein at breakfast!
Blueberries(eg bilberries) and raspberries, and my breakfast is almost complete.
I am 64. I listen to you, a 28 year old boy. You are impressive.
Oh gee, you spoiled it for me. I thought he was an old man, long on taurine ;-)
I train jiujitsu and weight train nearly everyday. My pre workout before each is 6g taurine and 9g of l-citruline malate and it has a significant positive effect on my performance.
Taurine, Creatine, Glycine and NAD are helping me with HIT hypertrophy twice a week and HIIT sprints and bike sprints, twice a week. I am 59 and getting stronger, slightly heavier, more muscular and faster. I also walk 2-3 miles a dog with my training partner.....a yellow lab mix 🐕
FYI ~ might be worth a trial of adding acetyl-l-carnitine (or carnitine, but there are additional benefits with the acetyl group) prior to HIIT. It helps shuttle fatty acids into mitochondria for ATP production. I also find CoQ10 helpful personally taking NOW's 400 mg.
Add l-citruline malate to that stack😊
Just dont take Taurine and Glycine together .... G blocks T Absorption .... Half-life of G is 30min to several hours.
You missed NAC 😂❤. DON'T DIE ❤
TAURINE ! Raw oysters, sardines, fish eggs , kelp 😂!
After age 50 the taurine is harder to be converted from your diet , so supplementation is necessary . It sucks to get old .
" It sucks to get old." It beats the alternative.😅😂
even from 40 or earlier l-taurine is of GREAT benefit.
I eat chicken heart in alternate days, it's full of nutrients, vitamins and minerals, plus a lot of taurine
problem is - most people are deficient in taurine and glycine nowadays. So taking it is pretty much mandatory. + taurin has very good calm effect - mild anxiety almost non existent after 2g
Agree
8g per day is so great for me man love this stiff
@@brandonyoung4910 Specifically, how has it helped you? Thanks !
I never had anxiety, but it triggered irregular heart rhythm in me. Not worth the risk.
@@lucianp2616 odd. 10-20g a day of taurine was miraculous for people with atrial fibrillation
there's also the importance for taurine for the testicular function, i remember it also helped get rid of microplastics in the body
microplastics fr??
Is there proof for that claim?
No @@snowie1
@@snowie1it’s the classic “I’ve heard” did treat statement like that as BS.
@@snowie1The closest thing I’ve heard to “removing” microplastics is chlorella but it gets redistributed and doesn’t leave the body.
Taurine was life changing when I started taking it. My sleep was comparable to when I was a child. Every morning I felt deep rejuvenation. And I only took 2-3 grams before sleep. That lasted for about a year. It started to make me wake up to pee 2-3x/night and I often woke up feeling hot. Something must have changed in my chemistry. Nowadays I seldom take it. My sleep stack is different but has similar effects.
You might be b12 deficient. Especially if you take supplements like glycine and nac which might deplete methyl donors and in consequence can lead to b12 (methylfolate) deficiency. The symptoms you listed can be caused by b12 deficiency.
Taurine is known to suppress sympatethic nervous sytem activity. Maybe is messing with your bladder. I was thinking to try it because I suffer from chronic pelvic pain and bladder hyperactivity. That's bad news for me...
@@an.20.24 I definitively need to pee a lot on morning when I wake up when I take 2g of taurine for a week. Also it is known to give you liquid poop past 2g a day
it wasnt the taurine. you can split dose 2-3x a day btw.
@@reinerheiner1148 this
Siim,
In terms of pharmacological effects of Taurine, the results can not be achieved with food sources as the there are competing amino acids and extraction of the taurine through food does not achieve clinically significant levels. This is how GLY/NAC works as well. Comprised functions in aging exasperate this. Isolating the amino acids have pharmalogical effects, food sources do not.
I like that you make your own B-roll
Thank you for the the very quick and detailed overview. The only think I would like to add is that while the effect on the lifespan may not exactly translate to humans, there exist no other supplement that has such a large effect on mice, so it could be good starting point. Regarding dosage, taurine levels drop significantly with age, and those statistics include part of the population that consumes taurine-rich foods. So it is reasonable to assume that dosage should depend on age.
What are typical doses seen in human trials, and ratios that you have seen for the indicated doses in animal studies?
Nice, but why don't you measure your taurine blood level?
I did that (took a amino acids blood test) and the only amino acid that was below reference limit was taurine. Therefore I supplement with 3 grams tsurine powder and plan to retest soon.
Very informative, and appreciate your fast cadence talking. I use Nutricost powder and get 4g per day.
I've been taking supplements since 1987, after having thyroid surgery, trying to regain some balance to my energy and focuy. I've tried everything, from Arginine to Zinc, which happens to be two of the first supplements that grabbed my attention, and showed some promise, but would fall short of a consistent improvement.
I've tried Hartshorn for the heart, Milk thistle for the liver, Ginkgo for the brain, and Cayenne for circulation. I've even taken digestive enzymes, with bile salts, to help with digestion.
Now I'm hearing about this, not so mysterious nutrient, that was added to cat food and Red bull, and had a supporting role in some workout supplements, that seems to play a significant role in all these areas of metabolism.
I started taking it sporadically, some years ago, because it had something to do with calcium regulation, which was an issue, with my messed up parathyroids, which control calcium levels. But I never took it really seriously, thinking it was a miner player.
Apparently I was wrong.
It's only been a few weeks, but it's showing some improvement in some of the areas that its said to influence, like energy, anxiety,, and general cognition .😌✌🏼✨
Increases my endurance.
It makes my muscles much much less sore from exercise combined with magnesium and B6 in P5P form only. I have a chronically too low LDH level (a rare genetic disorder likely), which causes my muscles to get extremely sore if I in any way overexercise. DMG (the only glycine form I can take without adverse effects) does the same for my body.
I liked and subscribed! I’m 32 and am now getting into longevity. I’ve been following Bryan Johnson’s protocol for about a year now but am happy to see others experimenting with supplements as well. Also, congrats on your high ranking on the rejuvenation Olympics board!
Welcome aboard!
Why did you decide to follow Bryan Johnson’s protocol?
@@NateB Probably because he gets the most publicity of anyone in the longevity world. SIIM is great but he is also young so some of the things he does or does NOT do aren't applicable to older people (for example about certain supplements he has said: "I'll start taking it when I'm over 40").
I add it to my green tea in powder form. It has no discernible taste and dissolves easily. I’m older, physically active, insulin resistant and don’t eat seafood every day, so I’m in a category where it could help.
try gymnema sylvestre for that insulin resistance
Absolutely loved this deep dive into taurine's longevity benefits! 🐾 It's fascinating how a simple amino acid can pack such a punch in the anti-aging arena. Who knew that something so small could potentially add years to our lives?
The studies you mentioned really highlight taurine's role in metabolic health-it's like the unsung hero of the supplement world! And let’s be honest, if taurine can help us dodge the aging bullet while keeping our blood sugar in check, it might just be the fountain of youth in a bottle.
Also, I can't help but chuckle at the thought of mice living their best lives with a 25% lifespan extension-talk about a rodent retirement plan! 🐭💼
Looking forward to your new book, *The Longevity Leap*! If it’s half as enlightening as this video, I might just need to stock up on taurine to keep up with all the wisdom! Keep up the great work, Siim! 🌟
I want to see a collab between you and Bryan Johnson. That would be awesome
That would be 🔥🔥
Would be indeed
@@SiimLanddont you think that bryan johnson is completely on the wrong track with his anti aging perception? (Vegan and stuff)
@@wodzefag8062anecdotally, how can you say that given what his (Bryan’s) results have been?
@@wodzefag8062 But Bryan doesn't encourage vegan diet, says it's optional. His son isn't vegan and has referred to him as an example
Taurine is interesting. But we don't know much about how it works in the body.
This is an idea, from a research article in Nature:
"The hypothesis of taurine as mitochondrial matrix buffer
The mitochondrial matrix as biochemical reaction chamber Stabilising the pH gradient by the presence of a buffer compound like taurine in the mitochondrial matrix transforms the matrix into a biochemical reaction chamber with a slightly alkaline pH 8.0-8.5. It is well established that several important biochemical processes occur inside the mitochondrial matrix, e.g., all the reactions in the citric acid cycle, fatty acid oxidation and some of the reactions in the urea cycle."
We also know that cats can't produce taurine and have to get it from their food.
If they don't get it, they get blind and have heart failure.
We humans creates enough of it not to show any disease, but probably not enough for optimal health.
If taurine works by creating a good osmotic environment in multicellular animals, it explains why it's so hard to understand it's effect. It's pretty indirect!
It's an amino acid, but not a building block of our proteins like other amino acids.
That it's produced in animals shows it's needed. But what's it's optimal level?
Thank you for the video - Poor mouse 😢
I started taking the recommended dose. 500mg. I now take 2000mg per . I feel terrific and think you should increase the dosage. Increases stamina and endurance
thanks for the comment. how old are you?
Who's recommended dose? Did you watch the video?
I take taurine powder. 2g in my am protein shake and 2g in my sleep stack drink.
Yes, I take it in coffee, along with glycine, which is sweet and replaces sugar, with no blood sugar spike
@@DinoFancellu I'm trying decaffeinated coffee with creatine, since it dissolves well and masks the taste well. I have not actually tried the taste of taurine since I have only taken that in pill form, but adding it to coffee sounds interesting. I usually do the coffee in weekends, when my breakfast is eggs, which are hard to combine with creatine because they solidify before getting warm enough to dissolve it.
@@DinoFancellu me too! take high doses glycine too and Im wondering how to get all the stuff into my daughter.... I was even vegan when she was born! And I had a lot of deficiencies in my body its insane!
If you have the MTHFR gene mutation, then there's a risk the homocystein level gets too high, which can lead to many diseases from cancer, to cardiovascular diseases, to Parkinson's, sclerosis, schizophrenia, diabetes etc Taurine lowers the critical homocysteine level.
😂why my brain read as motherfker.
I have had my homocystein level measured, and it was too low but I do also take high dosage B12 and methylfolate. Can't say what it was like before that. Only started taking taurine after I had it measured. Hope, it has not made it even lower?
Yesterday: Taurine and why it's amazing
Today: Taurine and why I won't take it
I'm beginning to get tired of your videos lol
Lmao, real talk.
He was praising it the whole way through. He doesn't take it because he get's a lot of it from his food. The title is designed to make you click, which I agree that is annoying. Also it's misleading because the point of the video was NOT "why he is not taking it".
A supplement being amazing and me taking it don't have to be mutually inclusive. There are dozens of amazing supplements out there. Do I have to start taking all of them?
@@SiimLandEspecially not if you're already getting it in your food, as you addressed in your video (for those that watched it).
Are you forced to watch his free videos?
Summary: Taurine is amazing, but he get's enough from his food.
Yes, maybe!
But the level goes down when older, as he showed in the video. Probably because the body produces less of it (from other amino acids).
He will need more of taurine from the next decade.
You didnt mention the positive effects of Taurine on sleep
Phenomenal
dont notice it, but almost nothing works for me in that regard, except melatonin.
Does it depend on when I take it?
@@NateB some people take a few grams before bed. I just take my 8-9g with meals throughout the day and then 1g before bed. It’s all been positives. Zero side effects for me unless I take 3+ grams at once, I notice a bit of a lack of drive to do things which is fine later in the day
@@NateB For sleep, take it some 30 to 60 mins prior to bed.
I eat chicken heart in alternate days, it's full of nutrients, vitamins and minerals, plus a lot of taurine
Is there enough taurine in Celsius to make a difference?
Is it ok to take Taurine if you have Chronic Kidney Disease stage 3?
I started taurine one month ago. Since I use a kinesiology doctor, I was tested and told to use 2,000 mg. daily on an empty stomach. I am taking it for a specific reason. To date I can tell NO DIFFERENCE. So, I researched to see just HOW LONG it will take to get into my system, so that I CAN know that it is BEGINNING to work. I was thinking maybe several MONTHS. Yet, my answer totally shocked me. I read that I would be able to tell a difference…….within ONE HOUR. ONE HOUR. I am frustrated and disgusted and frankly am ready to toss it. What do you have to say, please ? PLEASE ? Thank you. Today is 8-8-2024.
Look into Methylene blue don't ditch the taurine
@@lnsuvasquez2466 Okay. Should I take BOTH, insuvasquez ? Thank you !
@@carolcole570 I would I'm taking Methylene blue and adding more taurine in when it gets here
@@lnsuvasquez2466 THANK YOU ! ( I had 4 new bottles of the Taurine come in yesterday. Try my best to stay stocked up on all vitamins and supplements. ). Appreciate your advice.❤️
Dont care about longetivity of taurin, I take it for sports, u can also take in powder form like a protein shake, no need to swallow these big capsules
Yes of course
I take taurine since 2 years and i may not have gained muscle mass a lot but my i feel performance boost, no sure it has a direct corelation with taurine or not but i choose to continue taking it.
Why capsels?? Pure Taurin is realy cheap and it has no taste. I chug it with water no problem. Takes the edge of when I had to much coffe immediately.
I don't really like how there's so much focus on longevity nowadays. Everyone wants to live longer, ofc, but quality of life matters a lot too. Taurine has many other benefits that aren't related to longevity per se
I agree, personally a little weary of hearing very young people touting the benefits of select natural vitamins, snake oil and remedies for all sorts of things they have never encountered. Here comes the longevity craze...they can only speak to the theories and studies, of MICE.
I want to hear it from a 120 year old, a baby face just does not lend credibility! LOL
Regardless, we'll likely outlive the weirdo self righteous vegan types anyway, and enjoy life too!
the main thing for me, is it sounds like some suffering would be less with these supplements, helping with quality of life.
Not me . I want to live FOREVER ❤! Eyes mind heart and soul wide open. NO FEAR. Dave Pascoe ❤.
Really Siim . Show me ONE jap. Person that is 150yo. 😢. YOUR WRONG ❤. Ai will soon take the guess work out of it and all gurus and snake oil salesmen will soon be gone.
Nothing wrong with that
What do you think about Huberman's claims Taurine might damage capillaries?
interesting, better watch that
That it's nonsense and you should looks at many other sources that show the opposite
you can buy 1kg of pure taurine for € 11,99, a lot cheaper then those capsules
So, what's the "BIG CATCH" then...???
That you need to take 6 grams if the study was accurate
@@SiimLand Meh. I take it as a powder, with coffee, that's just a teaspoon full for me.
@@SiimLandWell, it's so cheap that it's not actually that difficult
I take 5gr Taurine every day. It helps with concentration and sleep 🙂.
Hi, what is the optimum time to take taurine? Morning or evening? And with food or without food?
I would be cautious it was recently linked to tumor growth in energy drinks .. after I took I had benign tumor on my kidney, so I'm scared of taurine now
@@theancientsancients1769how much of that was the rubbish in the energy drinks?
@@stephenfidler1005 I never drank energy drinks in my case , however I'm talking about that research ... It may not directly cause a tumor however it may grow one ? We need more research. Often these days people ignore facts they are passionate about something they take unfortunately. Also research has become biased
@@theancientsancients1769 hah! energy drinks are the problem! its the sugar and sugar shall not be mixed with coffin and amino acids like taurine. drink water and put taurine in your daily smoothie/ shake, Ive taken taurine for 4 years after my psychosis and its the best thing. I even feel it the days Im not taking it! so taurine, glycine, nmn, coq10, b complex, d3/k2, a superb multivitamin, adaptogens, I look younger and younger every day its insane!
I take 2 grams per day, and eat seafood 2 or 3 times a week. Sounds like I'm in range of whats good. 59 yrs young.
How many MG per day for men? Thanks
Siim is a longevity chad. 💯
I take 3g throughout the day. Should I be taking it all at once instead?
Thanks Siim.
been talking it since 1903 seems to be working
Many cool studies on taurine left not mentioned here. Taurine and sleep for example...
Does taking 300mg Magnesium Taurate help with getting up to the recommended dose of Taurine?
Not in a meaningful way
So..ok with monster?
Im a postman , i am 62 and quite fit , but recently because im on a hilly area i am slowly lagging i feel lactose in my muscles at some of the steep walks. Ive been on 3 tablets each morning and its a game changer , i have gone from 12 stone 12 to 12 stone 6 but the real change is my energy levels on this supplement , its taken me back ten years and i only pay £9.99 a month for a bottle of the supplement. my wife has ms and i have her on 2 of these a day as well . Its a game changer for me i am in a better shape than ten years ago . There is no catch , these taurine supplements are harmless try them for a month ,i tried them for a month first at 2 a day but really you need the three , please watch the videos and others about taurine it is a natural thing not like steriods . And like i said Only £9.99 for a months worth so no money making con .
Bryan Johnson spends $2M/yr on doctors supervision and optimizing longevity. His longevity ratio is 0.72. Are you saying all he has to do is take taurine and he can reach .75?
I take taurine, magnesium and creatine blended into low carb blueberry smoothies....
I also blend larger batches and potion then out 2-3 days in advance. Do you think there's any issue with these supplements being blended into a smoothie and sitting for 2-3 beats before consumption?
They don't denature or anything do they?
Creatine loses its effectiveness as it sits. Old advice was to drink it within ten minutes of adding to liquids but now I think it can be extended to within an hour, but probably not good to wait a few days.
i take 6 grams a day. bought a powder and mix it with my protein shake
But wait ~~ I hear it's good for eye health the retina has a high level of taurine..
??
do you have to do this all at once or can you take it 2 times a day
Anyone knows if taurine increases prolactin in men? I've seen this info circling in the biohacking community and there seems there's no consensus on that...
WHERE IS THE SUUPLEMENTATION LIST?
Slow down n smile little..
How nice for you to recognize his brilliance and thank him for his incredible informative presentation😳
All kidding aside, you are unlikely to achieve record longevity if you can't relax, destress, and laugh. Too serious and you will never make it.
Hey know, 5 kg of beef is totally doable on Carnivore! Still, wouldn't hurt to add some in ;-)
fantastic for the climate...
You seem to be aging well beyond your age... Perhaps it's the muscle/weight loss you mentioned in the vo2 max video (?) but it's quite apparent, at least to me and my wife.
I know it's unsolicited feedback but I thought it might give you some food for thought given your anti - aging interests and the fact that people are generally not great noticing this kind of changes in themselves.
Cheers.
A chubbier face looks younger?
@@SiimLand I think a "drier" face looks older. It's giving that tired middle aged man look. I kind of went in a similar direction after my cut from 92kgs to 77kgs and ending at about 9-10% bf. It wasn't as bad per my wife but it started to show apparently. I didn't lose strength which you mentioned in your video, though.
@@SiimLand yes it does
Looking more mature in the face, Siim!
I'm 43. It definitely increases exercise performance. The effect is subtle, similar to taking creatine.
I take 1g a day.
On days I'm playing sports, I'll take 4g that day.
The title of the video seems click-baity and misleading given the conclusion. As you implicitly acknowledge yourself: there seems to be no downside to supplementing taurine other than the cost, and potentially quite a lot of upside. One "use case" you didn't mention is to counter taurine deficiency which is common in older humans. The older you get, the more sense it makes to supplement. The quantity you supplement should probably gradually increase in old age, too. Supplementation seems the winner when compared to eating lots of tuna, since tuna and other fish often contain more heavy metals than you'd want to ingest. Not sure about bivalves and seaweeds. And obviously, this isn't just a dietary matter. Killing sentient fish so you can get your pRoTeiN and taurine seems like a poor ethical choice. By buying wild-caught fish you also support the industry responsible for 50% of plastics in the oceans, almost all of which comes in the form of nets. Those are the nets that seals and dolphins get caught up and drown in. 5-6 capsules of 1g of taurine daily doesn't seem so awful either. You can spread them out over each day. So... maybe you should re-write your take ("Why I'm not taking it")?
Hi, thanks for the feedback. In my videos I differentiate between what I personally do and take versus what I think is effective and has evidence. Taurine has evidence that it works in a certain population and like I said the clinical trials are done on people with poor metabolic health. A lot of people fall under that umbrella. I don't, which is why there's less expected gains for me from taurine. Maybe it'll change in the future, but for now it's not my priority.
Nice one 👍
Thanks ✌️
I was taking 2g and I'm gonna bump to 4g. Raw powder is cheap.
Thank you 🙏
Taurine 6g basically reset my satiety control. I took it with whey protein while exercising 5-7h per week and with BMI 28-9. It lead to huge BMI reduction in a few months. Not sure about the mechanisms though.
You lost fat just taking taurine? Did you change diet? Did you put on muscle?
@@User98681 My initial theory was that taurine simply worked by decreasing appetite and therefore changing energy balance. Yet there seems to be a noticeable increase in fat oxidation as well which may explain some of the effect on weight, too:
”fat oxidation increased by 40% with 6 g of taurine (p < 0.05), suggesting that a higher dose was necessary to stimulate lipid metabolism. Furthermore, a decrease of 4% was observed in the respiratory quotient when compared to the placebo group, suggesting a relative intensification in lipid and beta-oxidation [54]. Moreover, our results showed a glycerol threshold of around 0.40 µm/dL for both TAU supplementation doses, making it evident that the increase in glycerol levels was an effect promoted by the exercise session; however, this was in association with the results of the lipid oxidation, which were superior to the placebo. Thus, our data indicate that taurine promoted an additional effect on lipid oxidation.”
@@User98681 No change in muscle afaik. My diet was pretty much identical. The main difference was in satiety control. The difference was massive.
@@Neonomide good to know. I’m on day 2 6 g taurine 15 g glycine. Noticed results with my anxiety the first day. MAJOR reduction. Also been doing carnivore for 3.5 months now.
12g a day. 6 in the morning, 6 at night and i feel pretty f'ing good.
The mentioned taurine-containing seafoods also contain microplastics
So does meat
@@SiimLandagreed, hence I rarely eat it. Black lentils for life 😅
don't really care about the longevity benefits. it has many other benefits.
holy shit dude, you look totally different than when you got out of the military
I read your book like 10+ years ago
If it were beneficial to take taurine, then why isn't there stronger evidence for taking it? There is money to be made so if they can prove it they would.
Probably because humans create enough taurine, at least when young, to not show any deficency.
We probably need more of it from food. But if we don't get enough of it, we blame our frailty on old age.
It's of course not just lack of taurine, but many other things too that makes us not age well.
Taurine hasn't been researched enough to know how it works. That makes it difficult to find out how much we need.
I cap supplementation under three grams a day because of the recent reports about a link to colon cancer
Say what?
@@anonymissed3611 at some dosage in some people taurine in energy drinks can lead to over active hydrogen sulfide-producing bacteria in the colon
Taurine is very heat sensitive. Cooking it will denature most of it.
No, it's just as heat insensitive as other amino acids are.
Taking it in a hot beverage is OK, if that's how you like it.
I don't heat it, though, because there's no reason to do that.
you're also getting a lot of mercury in tuna
I tried Taurine back in 2020. The result was not good. The result was heart palpitations. I never took it again after that experience. I do not recommend it because the side effects exist and are not well documented.
What was your dose? Maybe sticking around those similar in diets and eat it together with food for slower release could help.
I take taurine along with l-arginine to inhibit my exercise induced supra ventricular tachycardia, which I found support for in a study. For me it reduces the risk of arrhythmia.
Yeah maybe this is why many vegans become carnivore! Much more glycine and taurine in animal foods.
I take 3 to 4 gr all at once before emsculpt.
Get Mike Fave on your channel
I recommend to drink Monster sugar free energy drinks.. each 500 ml can contains 1000mg of Taurine, 80 mg caffeine, guarana, L-cartein and panax ginseng extract. Costing only 1-2 € depending of the country. Comes much cheaper than supplement jars..
Hello from Japan. We love to eat squids and octopus, but not that often.
Don't eat octopus - they are VERY intelligent creatures.
@@Stappit yes they are even as inteligent as democrats and liberals.
@@Stappitmaybe, like pork, that’s why they’re so tasty!
Why would this video and the person speaking rule out taking touring just based on a few rat studies and metabolic health when touring has dozens of other directly positive ameliorative effects....????
Damn I've been using taurine it made my poop almost perfect. 😢
Positive effects on gut health.
Ty
If you are getting most of your taurine from fish, I'm afraid thats bad news in terms of microplastics. I would eat grass fed meat instead and supplement krill Omega 3 and Taurine to avoid the high microplastic content.
As per a recent study, all proteins including mear contain microplastics. Fish is not higher than meat
Additionally, most fish are farmed and the wild fish are being rapidly depleted. Grass-fed beef is more sustainable. I pursue the same strategy- supplement with 4 grams of omega 3 and take 6 grams a day of taurine a day.
From the various studies I've seen, seafood and grains and root vegetables are the worst categories. From this I would infer that grain fed meat is worse than grass fed meat. Grain fed meat may well be as bad or worse than seafood. Of course there is also a complex bioaccumulation effect with fish (just like with avoiding mercury) so the lower down the food chain the fish is the better.. i.e. whitebait, anchovies better option than tuna, cod, etc.
@@AncestralFuel4 grams omega3 daily? Isnt this too much?
@@ainahaganot really - lots of people take this much - the goal is to increase your Omega 3 index to the optimal level, which is 12% of your blood cells. I am at 8 now. If I hit 12, I will ratchet down my intake.
I took taurine for about two months- didn’t feel much, no effect on sleep or exercise performance…maybe a tiny positive recovery effect? Couldn’t take more than 3 grams per day without experiencing diarrhea.
THE TITLE OF THIS VIDEO DOESN'T MATCH THE CONTENT OF THIS VIDEO 🤬 TOTAL CLICK BAIT
How?
He explained at the end why he's not taking it.
Interesting
Brad Stanfield takes magnesium taurate.
I don't know the exact weight ratio but they are chemically bound in 1:1 molecular ratio, and 3..6 g of magnesium would be off the scale. It should work great but only provide a small dose, you would need to get the rest of the taurine elsewhere.
Short attention span? It’s because he already gets lots of taurine from seafood.
Looking hot in the thumbnail
Most folk recommend taking 1-3 or more often 1-6 grams.
5:19 -- Wouldn't that translate to a 100g of Taurine for an 100kg individual, not 6 grams?
No, because you need to consider the scaling of body surface area. In case of mice, that means dividing the dose per kg body weight by around 12.8.
I dont muscle test positive for taking taurine, but i do for resveratrol.
Did you muscle test while blind and not knowing what the substance you were testing was
@@SuitedPup. good point about testing blind. never really considered that but makes a lot of sense.
@@mjgrant1515 good luck!
Don’t speak so fast !
Eat some seaweed for iodine in case ww3 breaks out ☢️
Yeah most people are low in iodine