Dr. Stephen Phinney - 'The Realities of Sustained Nutritional Ketosis'
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- Опубликовано: 6 сен 2024
- Stephen Phinney is the Chief Innovation Officer and Co-Founder of Virta Health, the first clinically-proven treatment to safely and sustainably reverse type 2 diabetes without medications or surgery.
As a physician-scientist with 40 years of experience divided between academic internal medicine and industry, Dr. Phinney has studied nutritional biochemistry with a long-term focus on low carbohydrate research and its benefits for physical performance and insulin sensitivity. His career has emphasized the interaction between diet and exercise and their effects on obesity, body composition, physical performance, and cellular membrane structure.
A Professor of Medicine Emeritus at University of California, Davis, Dr. Phinney is an internationally recognized expert on obesity, carbohydrate-restricted and ketogenic diets, diet and performance, and essential fatty acid metabolism. He has held clinical faculty appointments at MIT and the Universities of Vermont, Minnesota, and California at Davis as well as leadership positions at Monsanto, Galileo Laboratories, and Efficas.
Dr. Phinney's clinical experience includes inpatient and outpatient clinical nutrition, directing multidisciplinary weight management programs in three locations, and he has designed, completed, and published data from more than 20 clinical protocols involving diets, exercise, oxidative stress, and inflammation. His extensive experience in the design of clinical nutrition trials in both academic and industrial settings has led to more than 87 peer-reviewed papers and book chapters on clinical nutrition and biochemistry. He is the author of four books, including The Art and Science of Low Carbohydrate Living and The Art and Science of Low Carbohydrate Performance, two foundational books on low carb nutrition science and nutritional ketosis that he co-authored with Jeff Volek, Ph.D, RD. Dr. Phinney also previously served on the editorial board of the American Journal of Clinical Nutrition.
Dr. Phinney received his medical degree from Stanford University, holds a Doctorate in nutritional biochemistry and metabolism from the Massachusetts Institute of Technology and completed post-doctoral research at Harvard University.
This talk was originally presented in August 2021 at 'Low Carb San Diego 2021' and has been graciously supplied by our friends at @LowCarbUSA . For information on upcoming LowCarbUSA events visit www.lowcarbusa...
Please consider supporting Low Carb Down Under via Patreon. A small monthly contribution will assist in the costs of filming and editing these presentations and will allow us to keep producing high quality content free from advertising. For further information visit; / lowcarbdownunder
I will not ever have sufficient words to express my gratitude for these broadcasts. I am solo keto, unfollowed, doctor perceives the "whole keto thing" as somewhat of a curiosity, etc. So I listen carefully to these broadcasts and take guidance from them. I have fumbled along, pretty much on my own, discovering sometimes the hard way, how important it is to "take" mineralized salt. I think I have found my own balance after losing 60 lbs. It has been almost a year and I am quite prepared to continue eating this way indefinitely. I am very strongly motivated to avoid the pain of inflammation. The difference it has made for me is astounding.
Same here, pain is a good motivator for me.
I'm like you - I started keto back in 2020 as the quarantine was just starting in my state, California. Only wanted to finally shed my belly fat and keto was magic for me. My family made fun, told me it would kill me - until they saw the results. Now several of them follow a low-carb lifestyle. I listen to these podcasts almost every day, some I repeat over and over.
What salt do you use ?
@@yomomma4261 pink Himalayan salt or sea salt works great
@@yomomma4261 I'm particularly fond of the Redmond "Ancient Sea Salt,", from Redmond, Utah. It was recommended highly by noted author Dr. David Brownstein, and by another YT KenDBerryMD. Available on Amazon. I get the 28 oz pouches usually.
i am a doctor in the philippines, and after being frustrated managing diabetes and other diseases the traditional way, I switched to a keto based approach, and have had a total 180 in results, but very few believe me. I can understand the sociocultural barriers
Hello! Same country and would like to reach out for consult.
I can’t understand why people and doctors keep trying the same failed diets over and over without trying something new even one time. Pathetic lack of curiosity and possibly a lack sanity. Wonder why people believe our medical system is corrupt to its core.
@@BeefNEggs057agreed 100% - pathetic lack of curiosity and quite frankly - stupidity.
I am a Danish blacksmith 66 yrs. old 176cm height. I started out 1. of October last year weighing in at 102Kg's. Went on (very) strict keto diet, which I am still on at this point. My weight today says 76Kg. I have not felt hungry during this period even though I eat very little. I have experienced great mental clarity overall, and I feel like I have more energy now, than I have had over the last decade of letting myself go. I have added D-vitamin, small amounts of electric trace minerals and sparingly raw apple vinegar cider every day. I have (re-)started working out, lifting weights and treadmilling, and lately adjusted my eating toward more protein and less fat as I am now (I believe) fully keto adapted. Going forward from here, I'll be gunning for flexible metabolism, focus on loosening all my tight joints, building sum muscle mass, get to around 70Kg's and eat sparingly and healthy. Thank you for this highly informative video.
Can I ask what you eat in a day? I've lost my keto mojo, hungry all the time and found it hard. But I NEED to be on this diet. Please help!
@@Candlewick14 depends on your budget but the best way I've found to sort of restart the keto/carnivore without getting hungry is to just buy a few ribeyes, cook them all at the same time and eat nothing but that and eggs for a few days and I get over the hump, then I can add in chicken, an orange or something here and there or whatever but it gets me in the groove again. good luck!
I suggest you listen to more of Dr. Paul Mason, Dr. Cywes, Dr. Ken D Berry, etc. and learn why you would not want to cut down on fat. That is, unless you are eating sugar/high carbs.
@@Candlewick14 I wonder how you're doing on this now if you totally have up?.. Usually people don't get really hungry on keto.. But the first week you may feel like you have the flu 😷😷... If you were hungry I would say there was not enough fat in your food....
Metabolic flexibility is a worthless exercise and does nothing for you apart from priming your pancreas with a load of insulin.
So interesting and informative. I started my weight loss journey a little over a year ago, following Dr. Jason Fung and other's videos and lectures such as this. They have changed my life! I recently met my goal of losing 150lbs! 😲😁. I eat low carb high fat and do intermittent fasting. I picked up ketosis strips and I've had ketones consistently since about three months into this...
I'm off my blood pressure meds, my osteoarthritis pain is so much better that I'm active again and swimming and my asthma is gone. All of this I did on my own and didn't cost me anything. I'm so thankful for these doctors who take the time to teach us. I've learned so much and I feel so well! I feel better than I have in years and years. Now I'm learning how to fast to maintain. Again thank you!🙏❤️
Jessica Johnson. What specific fats do you eat?
@@DavidBrown-bp4iq if she follows Jason Fung, then I'm pretty sure they're natural unprocessed fats like butter, extra vigin olive oil and coconut fat. Dont eat processed vegetable oils and your good to go.
Me too…. For over two years now, and I am now 80 :)
Intermittent fasting is key. It is not normal to eat every day all day. A ketogenic or carnivore diet has its value, but fasting is essential. Food is a big burden on the system and giving the body time to recover should be the default accepted practice. Instead, most people have elevated insulin levels for most of every 24 hour period and do not have efficient autophagy. The metabolic syndrome is primarily an overeating disease which is amplified by the poison called linoleic acid and the high carb (aka sugar) profile of the modern developed world diet.
Brilliant!
Than you I went Keto then keto carnivore a year ago
I am 81 years old was overweight heavy drinker high blood pressure
In that year I have lost 20 kg off all medication I am a rower and keep up with rowers decades younger I now have more energy than I have had in 40 years
My skin looks 20 years younger and many aches and pains have disappeared I do intermittent fasting do not get hungry
Thank you HFLC practitioners
Excellent. Inspiring.
Good on you! You have good genes too. Now you have turned on the longevity genes from the Beta-hydroxybutyrate pathway
It is so good to hear from an 81 year old. Goes to show that age has no limits with IF and eating keto or carnivore. Very inspiring. My mom is 86 and suffers with osteoporosis, gets pain in the bones, hips, knees etc and I do wish to see her have brighter days. She also has a defibrillator to help her with her heart arithmithea (not sure apelling). Any advice?
Really good presentation by Steve. I've been fat adapted for 3 years already.
I like how low carb presenters here declare their conflicts of interest like they have nothing to hide. You never get that kind of transparency with plant based gurus.
You never get that transparency from government or big pharma
Never huh? Speak in absolutes much?
Do you test your Ketones. Can you tell me how? Head the breathalyzer are not reliable. Do you use blood test with stripes?
@@Mangobed717It is speaking an absolute but I have never heard a disclaimer yet. They typically put on presentations because of their religious beliefs. Seventh-day Adventist had a lot to do with the formation of the new boom in vegan diets.
I just eat carnivore. Never count calories or track macros and it's incredibly easy. I don't care if I'm in ketosis or not. Never felt better! No more obesity, high bp, ibs or chronic pain.
Me too! Really, anybody can do it. I’m eighty years old and initially lost seventy pounds in the first ten months. Never felt better. Been over two years now.
Yep if you don't want eat beef, lamb or bacon you ain't hungry! You are craving or leisure eating
@@pennylacombe4763 Good on you that's awesome 👍👍👍 Ketosis must have longevity benefits and helping properties! So get ready 80s in the new 40 s
What about your 'Heart healthy whole grains' 5 times a day? 😉
I'm Piscevorian. Primarily Seafood & water creatures. Fermented meats, and occasionally vegetables & fruits.
The benefits of LCHF don't surprise me at all. 4 years ago with a carb addicted, BUT an open mind i went cold turkey into LCHF along with Intermittent Fasting. The initial 3 days (if i remember correctly at all) were a struggle. But i had read and reread and rereread all the literature on keto that the only pending thing was to put that into action. and it was just a matter of mere days before the miracles began showing up. No bloating post meals, reduction in heart palpitations....being .less hangry ...yeah.. and ofcourse the weight loss which is IMMINENT. And i wouldn't have done it if not for the free knowledge and information shared by great people like Dr Phinney, Dr Jason Fung, Mark sisson, dr eric westman, dr gary fattke, dr tim noakes, dr perlmutter, dr jeff volek, dr rhonda patrick, gary taubes..nina teisholz..and many more whom i am unable to recollect. Ever grateful and indebted to them 🙏🙏
Thank you for this video. I’ve been on Keto for over 2 years will always stay keto. I’ve lost over 80lbs, but that isn’t why I love this diet. I love that all my inflammation is gone at 52 and I’m always satiated. I’ve been hungry most of my life, on keto I’m not really hungry anymore. Love it.
Thank you again for this video.
yes carbs, release insulin and that drives more hunger feeling. So Glad to be off the carb rollercoaster 🙂
I am 54 year old woman - never overweight - but my brain, my body, stopped working for 20 to 30 years - I now realise what I was being told to do by doctors, by media, by nutritionists was wrong. Doctors would continually prescribe me anti biotics, dentists force you to have Root Canals - but never talk about the forever infection in your jaw, causing long term sickness etc.
It was my chiropractor who opened my eyes to the fact it was my so called healthy way of eating making me forever ill in such a weird way, I could function - but everything was a struggle - I had no idea how great and fabulous as a 54 year old that I can now feel.
I went low carb, then Keto and now I am 95% Carnivore - I love it - if I want a steak for breakfast I have it - I eat mainly steak every day - I have found a good priced reasonable one that I love, eggs, bacon, shellfish, fish, liver, heart, butter, bone broth, raw eggs, raw meat often and if the fat is tasty some raw fat, lots of animal fats and coconut oil.
Now 3 year Carnivore. Vegetables bloat me and cause terrible flatulence. No desire now to eat such a non exciting food as a piece of vegetable - just give me meat and I salivate and Woolf it down.
BRAIN now works - no more confusion over paperwork, no more dropping things, no more being clumsy, no more not being able to sleep deeply, - and so much more - a list of 100 things of benefit to me.
This is where it gets confusing when different doctors/researchers come up with different results. Here, Dr. Phinney is stating that high protein, in the absence of carbs, will still spike insulin, while Dr. Ben Bikman says that a high protein diet will not significantly raise insulin levels, unless accompanied by carbs...This is why it became important for me to do my own n=1 to see what foods spiked glucose/insulin and which ones did not. Lots of good info here, though, so thank you.
Listen to your body some are sensitive.
From what I heard in Bikmans studies, you do get a spike in insulin from protein. Just not as much as carbs and it normalizes a lot faster. Protein in the absence of carbs also raises glucagon. Most likely the reason why the insulin spike from protein is much more controlled is because insulin shuts down gluconeogensis. In that case it self regulates. 🤔
Been keto 2 yrs 22bmi 2yrs love this science of why it works. Changing took time, logging everything in a diet app makes it easier , takes time to reprogram your behavior, but understanding why makes it easier. I never crash crave.. or have to eat. And can fast... just because. No longer a slave to food is empowering...
The reason its so hard is because we live in a food universe that literally surrounds us with overwhelming carbs. There is no relief from being bombarded with them. We are doomed unless we can change the food industry.
...or get away from the advertisments. For that you have to kill your TV, and send someone else to the supermarket
Or build self discipline. Easier said than done I know but it's the only way
When I see processed food at the store, I say to myself, “Fake food.”
@@samuelreiter6412 yes! And they want to give us the cheapest ingredients for MAX profit$$$$ It's insulting to our intelligence.
Eat real foods not products, simple.
I'm doing low carb keto for my insulin resistance. I make sure to still get low carb veggies for the nutrients and I eat beef and chicken each week, making my own chicken stock. I'm in ketosis right now.
Always happy to hear what he has to say!
Thank you Dr. Stephen for the presentation. I am on keto diet for 6 months and I feel terrific! I lost 70 pounds. I can finally move without discomfort caused by my excessive weight. This would not be possible without a personal keto meal plan. It allows me to chose foods that I like to eat and it saves a lot of time. It also keeps me on track. At first I tried to make meal plans for a week myself but that failed. It was consuming too much time and after two weeks I resorted to my old habbits (yep fast food). This never happened after I got personalised keto meal plan. I am 6 months in and there was not a day when I would cheat!!
Sodium is needed for production of hydrochloric acid to digest meat...and other nutrients
How do you find out if your doctor cares about your health or profit? Tell him you are doing, keto, or carnivore.
Want to really see doctor get hateful? Refuse to take cholesterol lowering drugs (statins).....
Masterclass in long term ketosis. Lifetime of learning and worth itst weight in gold. Can't wait to hear the Dr. Palmer presentation he kept mentioning
I so loved hearing about the Inuit, and their diets. This is an eye-opener, the whole video as I've been on a "keto" diet for almost 2 years. So many benefits, but to realize I could be even healthier by lowering my carbs even further is something I am going to study further on. I am 69, 5'1" and 115 lbs as I lost 24 lbs and am building more muscle by working out with free-weights, and lots of walking. I do have very high cholesterol at 408 but refuse the statins.
Did you know that the Inuit can not be in ketosis. Interesting fact. It’s genetic.
Going higher in animal fat, beef trimmings, is steadily lowering my total cholesterol. My inflammation was massive, nearly died from Cov#$. Adverse reaction, hospitol, 5 bouts of Cov#$, rapidly developed multiple tumors, 2 surgeries to remove tumors, made mistake of allowing use of photon accelerator radiation in conjunction with uncut bolus caused incredible inflammation. The whole body muscle and joint pain nearly drove me to jump off the nearest medical building. Oncologists had NO IDEA what to do with me. I stopped the radiation at 46 Grys, dumped all meds and self treated stage four radiation toxicity wounds because wound Center had no appointments. Contacted Dr. Thonas Seyfried and plowed into sustaining ketosis. Dr. Phinney is THE MAN when it comes to understanding the chemistry, doctors do not GET IT. I am anticipating that my inflammation wont clear up till over 2 years on strict rumanant meat, organs and very high fat.
Keto is nearly correct, carnivore is correct.
@@yoso585 Only the far north Arctic circle Inuit. Because they consumed more seal blubber than the other groups, it has far less fat of the saturated kind. But it's all hypothesis.
Bravo, bravo, Dr Stephen Phinney, and all Low Carb Doctors.
adding in Dr. Jason Fung's intermittent and longer fasts has made it so I've kept loosing weight slowly over two years. Not gaining...back.....Keto plus fasting..way to go.
i had to change my gut bacteria to make keto/low carb work again. and i am still in the process.
i lost 25kg with keto in 18 months and was realy happy but then the weight loss stopped.and the weight slowly creeped back up to 119kg, 6kg below my maximum.
it took me several years to find out that 4 packs of antibiotics was the problem. i had a tooth infection and an ear infection, so i had to take them. now after trying out different bacteria and making yogurt to multiply them, my hunger goes away and keto seems to work again slowely.
the pathway that i found: SCFAs from bacteria => l cells => pyy, glp-1 => alpha cells > glucagon > gluconeogenesis. at the end, SCFAs lower blood sugar and insulin and fat burning starts again
Can you provide links or more detail on the yogurt and where you got the bacteria to inoculate?
I did Keto for 3 months but low carb before that for a few years. I just didn't have strong enough stomach acid to digest the fats and proteins. I too started making yoghurt, really hoping this will increase my good gut bacteria to help me go back low card high fat/protein again.
@@cometier you can get the culture's from the Internet. It's very easy once you get the swing of it. I make yoghurt every week, I do use a yoghurt maker because I basically heat for 24 hrs per the Gaps recipe.
Four months into keto, slashed my RA drugs by half, CRP from 2.5 to 0.8. Now, into 3rd year, 37 kilos (80+) pounds down.
Sorry, you're wrong. You need your low fat 'heart healthy whole grains' 5 times a day 😉.
@@shrimperlincs3395
Lmao, and she needs her FDA pyramid foods breads grains pastas all money endor$ed heart healthy logo.
And now to get even healthier Cheerios comes in heart shapes!
@@shrimperlincs3395 😂 😝
Well done. Awesome job
@@shrimperlincs3395
😆😆😆
Phinney is still my favorite source. Thank you!
48:02 BHB feeds same beneficial gut flora that otherwise eat butyrate from fermentation of fiber.
Dr Phinney is the Godfather of keto (Jeff too!) and it is always a good investment of your time to listen to his knowledge and insight. Kudos!
Dr Phinney seems to have stopped aging! He basically looks the same compared to his past videos from years past
I generally always ate a largely ketone diet-fish, fats, meat, green leafy vegetables. no carbs, OMAD. During the pandemic I strayed and my BMI went up to 33 & A1C was prediabetic. I switched back to my prefered real food (I cooked it), nothing processed.
My weight dropped from to 230 to 165.
My A1C is normal.
My Bmi Is now 23. Just four months!
Actually only eating the Mediterranean diet made me fat & diabetic. My normal weight is 155lbs. 70 years old, walk 8-10 miles a day and am in deep ketosis. My liver numbers ALT, AST are both 19 now. Before ketosis, I had fatty liver and ALT (1000+) from alcohol which I donot drink anymore.
Anyone can do this.
It's so great to see Dr. Phinney! He has been such a wonderful resource from the very beginning!
It’s not difficult. I’m generally in inadvertent ketosis. I focus on two things - protein consumption and elimination.
Eliminate sugar, refined carbs, grains, processed foods, seed oils and vegetables with high glycemic indices.
I eat keto and have done so for 3 years. I no longer track ketones. I feel great and it has helped reverse my prediabetes and helps keep my mucosal melanoma in remission. I have low CRP and got that within 6 months.
The movie *Never Cry Wolf* from 1983 partially touches on this because one of the characters is an Inuit man who is afraid to meet women because he lost his front teeth. In his own words, “this is what happens when a meat eater becomes a sugar eater.“
That book has been largely debunked. When pressed, Farley Mowat said something about story versus facts
One of the most memorable movies of my life.
@@ultmiddle4991 being a former Alaskan, I always knew that the Native population was in for some sad health issues because they ate a lot of Pilot bread and sweets….. diabetes was just getting a foothold fifty years ago and nobody was making the connections necessary to stop it. I lived mostly in the Bush and having good access to fish and other wildlife, plus having read a book by Adele Davis before moving Out, I at least was armed with some information so that I could feed my kids with an eye towards their future . Because I could only get to a town by plane or boat, dental health was always a priority. Luckily, I had found a book called “ The Tooth Trip “, written by a young dentist 🦷…… in a place like that education was a priority.
Diabetes 2
@@thejohnbeck Book aside , Carbohydrates , particularly sugars DO destroy your teeth !!!!!!!!
Best low carb channel - Always information that adds to my knowledge. Chapeau Ozzies !
A fine gentlemen. Truthful content.
Wish Dr P had touched on the bioavailability/effectiveness of potassium supplements to augment potassium ingested through food.
Thank you all for your feedback to my previous post.
Summing up the situation:
1. It bothers me the fact that when eating lots of bread, pasta, potatoes, cereal, bagels, crackers, biscuits, then the fasting glucose and the HB A1C(%) were lower by 10%.
I don't want to become pre-diabetic.
2. I like the keto friendly diet and I am in ketosis (the urine test shows ketones 5 MG/DL). I don't have food addictions, and I can eat as per guidance and also do intermittent fasting. My sources of daily fat are: one large avocado, plenty of olive oil, a cup of walnuts, salmon or chicken thighs. I will not add add butter, beacon or red meat to my menu.
3. I will correct my sleeping pattern which was hectic lately due to the corona-work-at-home new order.
4. I will reduce the eggs consumption to 2-3 per week.
5. I was very worried to become a LDL high responder. I am happy my LDL got even better and it is perfect right now.
6. Apparently there is a phenomenon called "Keto induced carbs intolerance". Hopefully a transient one.
Thank you all.
I'll keep you updated.
I think being in ketosis (aka low insulin) needs to be cycled on and off to maintain and reset insulin sensitivity. If you workout with high intensity, have poor sleep, background Chronic mental stress or are nutrient deficient (inc. Vit D, Protein, B12 etc.) your insulin sensitivity will shift and change in unexpected ways.
Chasing ketones via Urinalysis can be misleading. In theory you don't want to wasting your ketones via urine. You want your ketones to be used by your body so levels in urine will be low, yet your actually still in ketosis. The taste of your own dry mouth changes when you're in ketosis, this is easiest to notice when eating OMAD (nil by mouth).
@@shrimperlincs3395 First of all, thanks for your response.
I am taking 800 units Vit D so now the the level is optimal. Vit B12 is still a concern. Iron is low. Hemoglobin is low. I got these values prior to experimenting with Keto.
I would like to do keto/carb cycling. How many carbs shall I eat?
Unfortunately the medical establishment is not supportive at all, so it is hard to manage things by myself.
Thanks again.
Dr. P is absolutely correct. If weight mattered, then Mary Tyler Moore would most likely NOT have died from complications of diabetes.
She had type one diabetes, which she got as a child because her pancreas did not work. Type two diabetes is when you become overweight and it causes your pancreas to not work as well.
I really love Dr Phinney’s lectures.
After looking into health, nutrition and longevity I have come to the conclusion that you should simply avoid foods that cause increased inflammation in your body. I cut processed foods out of my diet, apart from grains, and for the first time in my life my psoriasis started healing without any treatment. I also lost 16 kg with intermittent fasting and I'm now in my ideal weight of 79 kg, 16% body fat, BMI of about 25.
Even strict ketogenic diet in for 6 months did nothing to my psoriasis (I measured blood ketones a couple of times per week to know I was doing it right, I also lost 10 kg). I started 7 months ago with intermittent fasting (16+ hours fasting daily, a couple of times per week one meal a day). But I only cut processed foods 4 months ago. Within 1 week after cutting processed foods I saw a massive difference in my psoriasis. Now 4 months later about 70% of my psoriasis is gone. Main focus of foods I cut was everything with vegetable oils, all except olive oil. This pretty much eliminates most processed foods. I don't notice any difference on how much carbohydrates or sugar I eat.
Same here .
I am 77. I lived for 7 years on low carb when I was much younger with far less problems. I need to get this to help the inflammation from many birthdays of arthritis. I am going strict! Hoping to be able to cut some meds over the long run. Thank you for your genius expertise.
After eating the SAD American diet and vegetarian diets for years with worsening health and start of prediabetes I switched to ketovore diet and intermittent fasting. Within 3 months prediabetes gone! My health was back ! Blood work was excellent and I feel great again. Went full carnivore diet awhile ago and doing even better. You want to be healthy eat the way our ancestors did we evolved eating meats NOT suger carbs grains or broccoli !
Hi Dr. Phinney, thank you for all your great videos. I lost a lot of weight, got a lot better. Doing Keto and partially carnivore since dec. 2018. the longer it goes, the worse all the Carb foods like cookies my children eat taste. You measure ketones from blood. Is the breathanalyser good to use? I am also thinking about therapeutic ketosis, where they say the ratio between Ketons and blood sugar has to be in a certain range - do you do that? thanks again, great work
So good to see Steffansson covered, he went through a lot for the sake of posterity.
It's not the "patient's" drugs. It's the drug company's drugs. Big difference.
Actually, who has possession of the drugs in the hypothetical drug scenario is unknown. Could be any number of players, including the patient.
@@yoso585 you missed my point
Be good to see the comparison of metformin against Berberine.
I feel like a better answer for "Lisa from FB" would have been that technically Keto was not developed for weight loss. It was developed to treat epilepsy and then applied to children who have autism. Therefore, you can "fix" your metabolism with keto however the bodies set point will still attempt to keep you at a certain weight. In that case where what you eat has gotten you to a certain point (but no further) you need to then look at when you eat and how often. So no snacking. Reduce your meals to 3 meals a day or two or one. So intermittent fasting... That being said. You gotta exercise and it's most beneficial to exercise in the fasted state.
In addition, ya gotta sleep 8(ish) hours in a 24 hour period and don't stress... All of those behaviors matter when it comes to weight loss. It isn't just about eating the right foods.
Some low-carb legends in that room...
Kevin Hall is trying to win the NiH/Harvard Ancel Keys award for lifetime contributions.
All true patient care is patient centric. Otherwise, it is increase the dollars in "providers" bank accounts
I used to love food, because our family and friends surrounded life and love with food. Dr. Ken Berry said, "Is it worth eating that cookie to wind up with amputations from diabetes?" That did it for me!!!😱😱😱 I got serious! Now I eat to live, not live to eat. I found so many great, and satisfying recipes for Carnivore on RUclips. It's getting better with creativity. There are so many more.....
I lost 75 lbs. on Keto in 7 months. I never felt better in my life, and at age 65!
Romans 14:2 "For one believes he may eat all things, but he who is weak (in the faith) eats only vegetables.'
Keto saved my life
Metformin is great at ameliorating dawn effect for me and further reducing insulin response. My glucose SD is like 5-7.
Could we please set up a debate with Stephen Phinney and Jeff Volek vs Stephan Guyenet and Kevin Hall?
Dr Phinney, why remove all diabetes medication except metformin? My doctor took me f of metformin when my glucose levels reach low levels.
Very low ketones on carnivore diet? Efficient use of ketones for fuel or protein too high stopping production ketones?
The latter due to insulin response suppressing ketone production. But of course you have access to additional glucose via the excess protein for the brain. For myself, high protein, 250 + and all meat drove my hunger to the point of packing on well over a pound a week for months in a row. Had to quit it.
I vote for both. You will note that in his chart about the two year results from his Virta study, the ketogenic diet group ended up at around the 0.4 BHB level, which is technically below the 0.5 level defined threshold for Nutritional Ketosis. I believe that a carnivore, "zero-carb" diet will simply expedite the process.
Plus, your body only has so much storage room for free protein, known as the amino acid pool. I believe that this pool is optimized to retain essential amino acids, and utilizes excess glucogenic amino acids for brain blood sugar requirements. When protein ingestion is extremely high, as Dr. Phinney mentioned, that bolus of released glucose from protein metabolism will indeed "spike" insulin and "kick you out of ketosis." Eating an "adequate protein" diet at 1.5g per referent (target) body weight pound and making up the difference with fat should result in ketosis for just about everybody.
@@bidnow2946 He actually said 1.5 grams of protein to referenced (lean body mass minus fat) body weight in KGs. Example 60kg LBM _ 90grams of protein.
Ketones don't matter much, but you can take them in supplement form if you want the health benefits.
@@LTPottenger I'm not sure exogenous ketones work as you're not in the metabolic condition to use and create them. The point of being in ketosis is that you're low insulin and using alternative pathways. Exogenous ketones will give the high levels in blood and urine but this doesn't mean you're using them or getting the benefits of ketosis.
I'm a tiny 4'9", obese lady with no thyroid, insulin resistance and 3x heart attack history and I gain weight on 900 keto cals a day, despite 1-2hrs yoga/Pilates/aqua class or swimming plus cycling at least 4 days a week! I try to eat OMAD
Starving yourself, especially with over exercise, may have wrecked your metabolism?
You must feed yourself to heal.
I would try carnivore.
If possible, go to a functional med dr
Get off all the plants, only eat beef, drink water, lots of salt… Stop all the cardio and just relax.… Can incorporate some weight resistance after you start feeling better
Ditto. 900-1200 causes gain for me too with exercise or without. I've heard from docs, physical trainers and nutritionists: eat less, eat more, relax, sleep more, lower cortisol, meditation, vitamins, don't workout, sauna, thyroid tests, b12 ultra, acetylcholine, or other burners. Agree with one comment that it seems like metabolism/hormones are broken by low cal for years. But most reseach and docs suggest metabolism isn't 'permenantly' broken. Tried everything listed by these commenters, and the original comment. I also tried carnivore 8 months, keto 3 years, veg-keto 2 yr, trainers 5 years, nutritionists 3 years, hyperbaric chamber, walking, running, soccer, volleyball, crossfit 1 year, different jobs, decreasing coffee, alergy test with machine, fitbit, thyroid tests, turmeric, acv in water in the morn, sparkling water, concierge doctor subscription, p90x 100 days, 430am classes with gym, 10pm or earlier bedtime, bluelight glasses, weight med doc, lemon water, no dairy, fasting 3-5 days per month for 17 month, pro/prebiotic, kimchi, sourkraut, intestinal flush, full nutrition panels $600, massage, footbath ionization machine, cavitation, the diet that increases caloric intake with a painful increase in the amount of high quality protien food, ice pack on body, 30 min morning sun, standing desk, morning walk same time daily, omad, intermt Fasting11-6(4 yrs), i.f. 20hrs/4hr (2pm-6pm) eat window, 1hr exercise fasted, keto blood monitoring, mouth taping, micro nutrient tracking, running, cold showers, sun, salt, sleep tracking, not working 4 months, avocado, scale monitoring (9 yrs), coconut oil in face/hair/skin, marrow and gristle collagen, high end vitamins, college oils, brewers yeast, logging food (12 years), using fitbit (3 years), decreasing commute, going on vacation, magnesium spray, potassuim/magnes drops in water, exo ketone on subscribe and save 1 year (super expensive) and chiropractor. Lately I wonder if its a pituitary tumor from a bloodloss trauma event based on symptoms or maybe sleep apnea. However normally keto/carniv would suppress/prevent cells from forming tumor and not eliminating bad cells that result in cancer so who knows. There are a some of us out there who are complete anomalies to what most people's would consider metabolism/endocrine/hormone functions that are predictable for others. I feel your pain. healthy prior to first of 3 kids.
How is your thyroid replacement levels? Should be tested every 6months at least T3 & T4 ( don't think tsh applies as you have thyroid removed) Low levels make us cold and gain weight easily.
When it's stopping increase , it's plateau off. When it's stopping decreasing, it's level off.
How to get such high percentage of fat and keep protein intake on a relatively low level?
I've struggled with less than 20g carbs per day with much higher heart rate and pulse. When I wake up, my heart is beating out of my chest. It's scary. I've gone up to 39 carbs per day to see if that works.
Is there discussion concerning the resulting intestinal microbiome and ketosis? Those diverse species control inflammation and a whole lot more . . . and I'm not sure I've heard them described in this talk. Please someone tell me what I've missed. Inflammation is my nemesis (as with many of us). and I am adding back in various veggies to diversify/support them. Thoughts?
This all makes eating so confusing! We are regenerating the soil in our yard and building the micro biome there. View dr. David Johnson and the Johnson-Su bioreactor info. You may find a solution/some understanding there. Turns out healthy, living soil has the same microbes as healthy gut 🤔
Dr. Phinney is correct. Being on Medifast (same as Optifast) caused me to lose my gallbladder back in the '90s. I've had to fight post-cholecystectomy diarrhea ever since, which makes it very difficult to do keto. Would love to know some remedies for that. Have about 50 more lbs to lose.
On hard part for people I have known is that they thing they can eat all the meat they want and end up consuming over 100 grams of protein a day, usually high leucine which is insulinogenic. They "have" ketones but they also are often doing a lot of gluconeogenesis and may have fasting blood sugar in the 90-108 range and probably have high insulin needs. I have found that when protein gets down too, the fasting blood sugars drop. I saw an experiment where people in deep ketosis were given insulin to push their blood sugar down, and they had their blood sugars pushed down to 20 mg/dl without hypoglycemic symptoms. This can only happen with high ketones and the brain functioning on ketones. People who just eat low carb but still eat a lot of protein are making glucose. In fact the fate of every amino acid you eat is to be eventually made into glucose or ketones. Even someone who is gaining 15 pounds of hydrated muscle in a year is only retaining a net about 5 grams of amino acids per day. On 100 gram intake, 95 are turned into glucose and ketones (and byproducts like ammonia and urea).
So good, I had to listen to the whole thing twice.
I’m nearly carnivore for the past year. I tested blood ketones regularly for a while and they were often low. Maybe too much protein? Type 1 diabetic since 1970, A1c under 5 for a year, but again not much ketosis.
Apparently, ketones get produced, and used, efficiently in those who are fat adapted. My ketones are generally quite low, but my blood glucose is always low end.
Do you eat fatty meats?
Low is not a number.
Yes, likely too much protein or indeed too much total food if you are also gaining body fat. Review the slide and comments at 8:00 again.
Wow! 👍
Most studies I've read are 8 weeks, and it infuriates me every single time someone tries to use them as gotchas.
That gene expression note, definitely means it was turned off in my mother. I was born with inflamation through the roof. Dairy intollerate. Cradle cap, (thick crusty skin) and was fed soy, as mothers milk or cow milk was not digestable for me. Then my whole life I was metabolicaly non-adapted. I felt puffy, even as a semi athlete, very active for ever. Until the past 2 years. Lockdown, activated pre-diabetus hard.
Went OMAD, super high saturated fat, and good animal protein.
Now I understand that butrate was a key in repairing my non-adaption, or metabolic broken body. I flip and flop on the deep ketosis plan. I'm around 100 carbs or less in general. Mostly green veg, raw and fermented beveredges. Some cardio and some weight training. I can finally build muscle. I used to eat 5 or more times a day. I couldn't build any muscle that was defined and tried to for a few years in my 20's. I'm 40 now, much leaner, have a ways to go more. 28%bf to 19% in 5 months. BP way down, 25 points 140 down to 115. Muscle is bulking up a little and have more strength. Insulin breaks down muscle, if it's high all day. Look up Sarcopenia. Thats why.
This lecture is very helpful. I'll consider deeper ketosis. But the one meal a day definitely kicks me into some BHOB production that feels great. Much less stress and inflammation. Joints feel better. Mouth ins't dry anymore. My blepharitis for life has disappeared finally lately too. Less puffy eyes. They were at least a 1/4" puffed out from my eye socked. I would puress them back in every day. I notied one day, they are way sunken in. If you have eye disease or burry vision even if they say the prescription is right. That could be the problem. But if you are here, you are already low carb and hope your troubles go away too.
Love this channel
How does the protein level translate to ground beef needed to eat in a day? Is it based on current weight for the protein level? So if starting weight is 200 lbs after losing weight the protein per day goes down.
A meat has about 25-30% protein of it's weight, if I remember correctly.
Dr. Phinney recommends basing your target daily protein based on the ideal weight for someone of your height and sex, not on current weight. He is very enthusiastic about limiting protein, more so than many other docs who practice low carb.
Listen to your body-eat until satiated at that time. Some days I eat more or less.
Ketosis is low insulin.
Protein is insulinogenic.
Excess protein means higher insulin which means you'll not be in ketosis.
However, Ted Naiman's P E Diet and the protein leverage hypothesis show that you'll keep consuming food until your internal protein target is met. Unfortunately this often also means excess E (energy from Fat or Carbohydrates) is consumed along the way to that target. The fat won't be Insulinogenic, however, if you're in energy excess from consumed fat you won't be using your body's own fat stores.
Next consider your exercise intensity. If you're training hard and breaking down muscle it needs to rebuild or you'll be in catabolism and will waste away. You need a line of defence against Sarcopenia as you age. Your muscle density and volume is that defense.
So maybe 1g to 1.5g of protein per kg of bodyweight per day. As you age you need the higher end. If you make your muscles soar a few times a week you need the higher end.
I am 62 years old and about 185 pounds. I eat 1.5 pounds of meat plus eggs per day. I am a bricklayer and ride dirt bikes so I’m pretty active. I’m going to probably try to get more protein though.
Thank you.
Did you consider that the weight regain was muscle mass and not fat????
Weight is a tricky metric. Good point.
8:30 ironically the acronym for Stadard American Diet is SAD 😅
Phinney and Volek… two well known and well respected names….
Is that Dr. Westman in the audience @1:03:18? Dr Phinney and Dr. Westman in the same room, Awesome!
Bravo!!
Thanks, great lecture.
The graph at 1:01:38 on “Estimated Sodium Excretion and Risk of Death from Any Cause”; why is that olds ratio scale not linear?
Thank you!
This really good evidence based information. An open question is whether daily is a minimum daily requirement or an average daily. My belief is that daily should be stated in *average* daily requirements. And the feeding timeframes should be stated in hours (30-40) per week. These feeding times are then averaged across a longer time frame than a single day. Our historical diet indicates that this has to be true
Would continuous glucose monitors be better for tracking and feed back to the people in the group?
You cannot reliably infer from the CGM what your insulin levels are.
I went on a 12 day water-fast. My Tg improved by going from 268 to 199. But why didn't my Tg go lower?
Fasting is bad idea. Jast do keto
The main problem with sustained nutritional ketosis is that the body stops needing to turn amino acids into glucose for the brain which means that there is no need for the immune system to hunt down damaged and malformed proteins to break down to provide raw materials for gluconeogenesis. So sustained nutritional ketosis actually opposes protein hunting autophagy and shuts it down because you only need ketones for fuel. Passing into and out of ketosis and ramping up gluconeogenesis is what triggers the body to look for malformed proteins for fuel. Now since nutritional ketosis massively slows down tumor growth, the need to autophagize tumors isn't that great, but it's probably better to come up for air from ketosis and activate protein hunting autophagy. By definition, nutritional ketosis is the point where the body does not need to substantially undergo protein hunting autophagy anymore. They are really alternate and opposing mechanisms of fueling the brain. Autophagy decreases the longer you fast and the longer you are making ketones. 3 shorter fasts (24 hours) theoretically do a much better job of protein hunting autophagy than one long 72 hour fast but again the longer fast slows tumor growth so it may be better to enter autophagy on the way up from ketosis rather than on the way down.
you are stating concepts that are opposite to what I have read ie "the longer you fast the more autophagy" and you say opposite. Could you reference who's work you are repeating please?
I’m thinking that people ‘diagnosed’ with Type 2 Diabetes on insulin, and couldn’t get off, may have actually had LADA.
Latent
Autoimmune
Diabetes in
Adults
Thus they may have been misdiagnosed as Type 2 Diabetes patients.
LADA requires other tests that diabetes antibody tests which likely were not done.
This misdiagnosis occurs frequently in people with LADA.
The interesting thing, though, with this type of Type 1 Diabetes they may benefit from adding Glucophage (Metformin) to their insulin dosing, to improve insulin sensitivity to the exogenous insulin. Those with LADA, despite dramatically adjusting their diet (as he suggests), still have more insulin resistance than a typical person with Type 1 Diabetes (like those which start in childhood).
Reminder to those on Metformin, monitor B12 and serum folate as level can drop when on the drug.
“In range” lab results does not mean optimal.
Monitor RBC Magnesium as well.
Monitor blood sugars well.
Ask doctor for a copy of your lab results/units of measure, exact test name and reference ranges as it is your legal right.
Terbaik
How does one repair their metabolism if it's gone down 400kcals or something, like he said at the end of this video?
Eat big portions of food. Make sure you get enough protein and fat. Your body needs to perceive a state of abundance. You can kick-start your metabolism by eating properly for at least 3 days. Make sure the food you eat is all natural and non-processed.
By Fasting, to increase metabolism.
You might also look up the concept of “reverse dieting”.
eat meat, lift weights, fast, don't count calories while eating, don't snack.
I wonder what proportion of study participants had ADHD. Like unmedicated ADHD folks would be more likely to drop out. But medicated ADHD folks are gonna have some other issues like maybe elevated blood glucose or other inflammation markers because the stimulants kinda keep you in fight/flight mode. People with ADHD are much more at risk for developing T2D and I dunno what risk is attributed to executive disfunction (behavioral differences caused by neurology) or whether long term stimulant use exacerbates insulin resistance.
I’ve done keto for years. I finally got a device to detect blood ketones and even though I know 100% I am under 20 grams a day I get a ketone reading of 0.2-0.3 99% of the time. The highest I ever got was 0.6. Only thing I haven’t tried was eliminating stevia from my coffee. I use liquid stevia with no bulking agents.
Check out Dr Annette Bosworth. I like aiming for the Dr Boz ratio...
It's very possible that low ketone levels aren't due to not being in ketosis but in fact due to your body actually using the ketones you're making, hence them appearing low on your tests.
Blood ketone levels diminish considerably the longer you don’t eat carbs, there are several talks on the possible reasons for this on YT.
How much protein do you eat?
For some reason, my blood Glucose and A1C (%) rose with Keto.
Following a 4 months keto diet, my glucose went up 70 to 77 mg/dl, and my HB A1C (%) went up 5.3 to 5.7.
I'd appreciate your comments.
E L. What have you been eating?
You need to measure your blood ketones and make 100% sure you're in real ketosis. A lot of utter garbage processed foods with lots of carbs have the word "KETO" on the box label. If you eat this every day, guaranteed you're not in ketosis.
you must be doing it wrong. Something you're eating has a lot of carbs in it. It will also help if you restrict your feeding window to maximum 8 hours. Intermittent fasting has scientifically proven to show great effect on blood glucose levels.
@@DavidBrown-bp4iq My Keto diet: moderate poultry meat, salmon, eggs, lots of veggies, olive oil, green olives, avocado, veggie soups, walnuts, half a cup of steel cut oats, no fruit.
@@EL-yi6df if you eat lots of vegetables, you might get a lot of carbs. You have to be careful eating low carb veggies and not too much. Oats also have way too much carbs.
Whilst veggies and carbs have fibre, they're still carbs and would've probably lead to you not being in kurtosis.
Weigh your veggies, not too many and the right type (Google low carb veggies)
👋🙂🇦🇺 Thanks for sharing your experience and knowledge ❤
Do the viewers of this channel recommend any particular online keto/carnivore forums? Thanks! 🧐
Zeroing in on Health is great. Masses of information and long-term gurus. And Carnivore for Women if that applies. (Your user name doesn't give a clue on your gender.) Both are on Facebook.
@@yamlwoz thanks!
Dr Ken Berry is a good 👍 one to follow. I follow him on RUclips. He’s live on Mondays.
Dr. Berg on RUclips
Is weightlifting OK to do while on a keto (or carnivore) diet?
Dr Shaun Baker
Yes.
Yes. I've been carnivore two years and lift weights.
Ofc
definitely yes!
Super lecture! This App looks great. A patient centric program, patient centric App. A peer support group. In constant contact. You could do this with SARS-CoV-2 instead of Mandating it all which won't bring anything except taking away people 's right in making decisions about their own health and reducing them to dummies.
I had a cancer diagnosis in December 2021 and immediately went keto, lost the extra kilos quickly. But I've found it so so hard to stay on, now weight is back up and I feel defeated. How can I stay on keto? :(
Eat carnivore
See FRED EVRARD video on the subject
So eating 200g of brussels sprouts and 500g tray of 25% fat beef a bad thing?
Not bad at all, but you can ditch the sprouts…yuck.
Why would you think it would be?
@@jksinorbit Hey I love my itty bitty cabbages! :)
Mr. Sojek. Eating cruciferous vegetables is a very good thing. Eg. broccoli. These vegetables contain sulforaphane. Anti-cancer.
sounds good to me. You dont need to be in strict ketosis to be healthy. Metabolic flexibility is more important.
Can ketogenic diet, over time adversely affect the liver, as the liver has to deal with a great deal of fat?
NO. Liver killers are fatty liver due to too much insulin without a break (eating carbs and often)
Being in permanent ketosis can't be 100% problem free. I think the goal is metabolic flexibility. Being able to easily shift in and out of ketosis.
Don't eat a great deal of fat. Eat no more than you will use. If your keto diet gives you less calories than you use, you'll burn some of your own fat. This is good if you have more fat stored than you need. If you have the right amount of fat stored, eating enough fat won't hurt you. Eating too much fat is bad for you. Different from eating too many calories in the form of carbs, but still bad for you.
Are ‘polyunsaturated fats’ pro-inflammatory?
Our white Anglo Saxon race were carnivores too. We come from the hyperboreans, Norse Pagans, Aesir Vanir, Tuatha de dannon, celts, vikings, etc...
The Inuit (and Stefansson) didn’t salt their food at all. How did the Inuit get enough potassium?
They didn't sweat. Also the seafood they ate is probably higher in salts, especially skin, organs etc.
Meat broth contains potassium.
What date was this presentation given?
"This talk was originally presented in August 2021 at 'Low Carb San Diego 2021' and has been graciously supplied by our friends at @LowCarbUSA "
From their description.
OEither a fast or refeed can stop platoed
Don't get me wrong. I'm for low carb and all that... but... can anyone tell me...
Is there any record of a indigenous population that actually lives their lives in a state of permanent ketosis. I heard that even the inuit with their seal diet did not live with permanent ketosis.
Is this true?
Its a cycle. You fill up fat reserves and then go on burning them till empty, then you start filling up again. So you dont stay in permanent ketosis. This is what I have understood, I am an engineer, not a subject expert though.
What did the Inuit have access to that would have kicked them out of ketosis?
I mean... probably not because yeah babies are actually fed with breast milk and they go out of ketosis because of the lactose and perhaps the protein.
Carbohydrates are not evil per se,
Processed Carbohydrates, aswel as seed oils, and the loss of the body's ability to switch to fat burning mode (Ketosis) by eating carbohydrates three times a day and preventing the Insulin level to return to normal, that does the damage.
It's excess Insulin that causes damage, both directly and indirectly, and generally speaking we don't even think about it, or get round to measuring it...
Unfortunately partly because Ancel Keys in 1980 promulgated 'faulty' research findings that left us with the idea that if we eat fat, it makes us fat, we substituted sugar for fats, which has compounded the situation.
We now have to try to re educate everyone, which is extremely difficult.
We also have to encourage everyone to eat less frequently, and when able (when they have become fat adapted) to practice intermittent fasting, which most people will reject instantly, because of their present state of 'carbohydrate addiction'. They know perfectly well that if they go without food, their glucose will rapidly come down and they will be forced to eat some more carbohydrates to avoid Reactive Hypoglycaemia.
It's all a bit of a vicious circle...and needs a total rethink by everyone concerned.....
It should be possible in a short period of time, but somehow I suspect not.
Yes. I do believe they have a knock out gene, There’s no need for it.
yo we wanna check Wesmen and Phinney talk to each other in a podcast free-form discussion for a couple hours with some questions at the end.....can ya make that happen?! lol