First mass reactive vaccination campaign against Hepatitis E | Etienne Gignoux

First mass reactive vaccination campaign against Hepatitis E: main results of observational studies
The first mass reactive vaccination against Hepatitis E took place in 2022 at the Bentiu camp in South Sudan. During which, Epicentre assessed vaccination feasibility and acceptance through coverage surveys and conducted focus group discussions on acceptance and monitored adverse events following immunization (AEFI) for pharmacovigilance.
This study found high vaccine coverage, good acceptance, and demand from the population. There was no evidence of increased risk of foetal loss among vaccinated pregnant women. Despite the small number of cases, the reduced dose regimen appeared effective in reducing disease risk in this highly exposed population.