Thank you for your information. I couldn’t agree more as my husband is “dealing with” prostate cancer and following the metabolic protocol. The only thought I’d add is, “Good luck finding an oncologist who believes in any of this mumbo jumbo!” I just walked out of our oncologist’s office a couple of weeks ago because of his mocking, knowing it all attitude. I will never return. Dr Seyfried is a hero and I pray that the medical world will wake up one day…but I doubt it.
I’m very sorry to hear that. This reaction of your physician is the reflection of the pharma industry. Oncologist should know that cutting out sugars and decreasing glutamine can be immensely helpful. I have a had patient that had done metabolic therapy in combination with high dose intravenous vitamin C weekly. He only required very low doses of chemo and for a short time only.
Prostate cancer is very pernicious, the urologists are butchers, they use a meat cleaver when they should be using a scalpel. Prevention is key gotta drive insulin to baseline by going 0 carb, the continual insulin spikes over a long period of time are extremely dangerous and our urologists need to stress this but the will not because they benefit from our misery.
Jonas thank you for your clear and thorough explanations. I understand that some folks consider that your presentations are too long but I very much appreciate the thorough descriptions of biochemical mechanism involved and scientific publication references.
@@JonasKuehneMD It does help in my understanding that I have a medical science background with particular interest in biochemistry and microbiology. My main interest is to help my partner who is in remission from breast cancer and my friend and former colleague who is stage 4 breast cancer in the lungs and about to restart treatment. I came across Dr Seyfried in my research but even though I understood what he was saying, it wasn’t convincing enough to share with folks without much basic background knowledge. By contrast your presentations are distilled and much easier to follow. Thank you!
Suzanne Somers wrote books on Cancer. She had breast cancer. But cancer finally did kill her. So many studies are done and what works for some doesn't always work for others
That is very true. I think it’s important to attack the disease from different angles. Therefore, metabolic therapy, mixed with supplements like green tea or berberine is a good start.
I believe Suzanne summers lived 20 years with breast cancer. It's possible she would have died much sooner without her nutrition and natural remedies. I know several people who did not do chemo and other mainstream treatments and did alternate treatments. All have died but lived MUCH longer than the doctors said they would with regular treatments. My wife's grandmother was given maybe a year if she did surgery and chemo. She did natural stuff and nutrition and lived 7 years
@@kennygee2715 Suzanne sommers had done chemotherapy. There is no one shoe fits all. I know many people who done chemo and are living today a normal life, and others I know that died. Don't look one way when you cross the street you will certainly get hit by a car. All bodies need the right foods, exercise on a daily basis. Fruits vegetables, nuts and some fish and some meat limited. Science plays a very large role in our lives and so does nutrition. If it were not for the advancement of medicine we would not be living as long. I only look at facts not fiction
@@JonasKuehneMD btw I just noticed you are from Los Angeles. I have a friend who has recently been diagnosed with leukemia last month and is now currently doing chemo and it's pretty brutal. Are there an doctors in Los Angeles area that you know of that specialize in treatment that doesn't involve chemo and instead targets diet and less harsh medications? She's only 43, but I feel like there are better options than doing just chemo. Thanks in advance
I’m so glad I found your channel today and without hesitation subscribed. 😉 I look forward to perusing your many videos. Curious if the Bigelow green tea is organic?
Dr. Thank you so much. VERY good comprehensive video on EGCG. To be clear, does EGCG prevent glutamine uptake into ONLY cancer cells? Or both normal & cancer cells? How would this effect recovery from exercise? TYIA
What is the ideal amount of green tea per day? I drink 2 cups of organic oolong greent tea a day. Should i drink more. Cancer survivor, serious about preventing recurrences.
In Japanese studies, they found that drinking 10 or more Japanese sized cups per day Showed a significant decrease in cancer rates. You could also consider supplementing with EGCG at the dose recommended by the manufacturer.
A common recommendation by the manufacturers for EGCG is 1800 mg of green tea extract daily which has 45% EGCG. There is not much research on appropriate dosing, but in general, the manufacturers will push for the highest dose within safety margins to sell as much of the product as possible.
@Dr Kuehne could you tell me how much EGCG I should take. I'm at the very beginning of my journey and havent even seen the oncology team yet. And should I take it intermittently?
I have not seen studies discussing the specific dose. Most manufacturers of green tea extract recommend 1800 mg daily, with 45% EGCG. This is not medical advice, of course and you should always ask your physician first. In general, though this is a dose that can be taken daily.
White tea is an excellent choice. Very high in antioxidants. As for green tea, the Japanese studies generally showed people drinking upwards of 10 small cups daily.
Is it important that it says ECGC or just green tea? And how much coffee is allowed, I found capsules from maybe two manufacturers, so I'm wondering how important it is to look at. Greeting💝
From the international journal of molecular science: Recently, in vitro experiments suggested that EGCG and its metabolites could reach the brain parenchyma through the blood-brain barrier and induce neuritogenesis. These results suggest that metabolites of EGCG may play an important role, alongside the beneficial activities of EGCG, in reducing neurodegenerative diseases.
It’s difficult to find exact doses in the literature. The study from Japan shows that 10 Japanese sized cups daily or more significantly lower risk of cancer. As it comes to EGCG supplements, most manufacturers recommend 1200-1800mg of green tea extract with 45% EGCG.
“Studies suggest that decaffeination can lead to a minor reduction in the levels of catechins and other antioxidants compared to regular green tea. While this decrease exists, decaf green tea still contains notable amounts of polyphenols and antioxidants, which contribute to its health-promoting properties.”
Not necessarily. Your own body makes glutamine as it is a non-essential amino acid. For leaky gut I would suggest a gluten-free diet and glucosamine supplement
My oncologist won't hear of anything about glutamine blocking. he said don't waste your time. I am changing doctors. I am stuck taking prednisone and want to fast but he thinks I will do immunotherapy again so he is giving prednisone to manage the immune induced hepatitis. it isn't working. help I want to start a but take egcg again. I am trying to find a doctor on my plan that will allow this. Perhaps just drinking a few cups of green tea per day will help?
I’m sorry to hear about your experience.In my opinion EGCG and berberine, a ketogenic diet, as well as weekly high dose vitamin c iv therapy (if G6PD is normal) can work complementary with low dose chemotherapy. of course you need to discuss any diet, supplements, or other modalities with your treating oncologist to make sure it is safe for you.
One of the issues is weight loss without adequate calories. It certainly can be done, but would need to be at least discussed with a treating physician. If soft foods and purees are OK, there are certainly some possibilities. Also, protein shakes with heavy whipping cream will be calorically very dense.
@@stanleyyu2079 I hope your recovering brother, I too am fighting the shit , it isn't easy I know, many days I just fast as it is no food for cancer, but when I eat only low low carb to feed my body from getting too weak , protein and healthy fat select green super foods ,
I love it BUT can we please start adding the fact that cancer cells can also survive on a ketogenic diet/ without glucose consumption? They can adapt their metabolism to fit even ketones (I guess this is not true for all cancers, but still). I always hear the basic point of "cancer eats glucose" but it's not that simple! Still keto has many benefits.
You are correct, it is not that simple. The two main fuels of cancer cells are glucose and glutamine. The theory that cancer can evolve to feed on ketones has not been proven as far as I’m aware. This is because the mitochondria are defective in cancer cells. Fermentation seems to be the only way to generate energy.
@@nikesonmyfeet1234I worded it wrong but the point still stands. Cancer can survive on a keto diet. If it wouldn’t, everyone on keto would survive indefinitely which they don’t. It’s not my duty to present papers for you. The fact I stated stands and that’s all I’m gonna say. If you can’t work with that it’s your problem
Thank you for the feedback. I agree, sometimes they get a bit longer. I usually opt for around 10 minutes but if it’s an exciting topic with a lot of information, I might run a bit longer.
@@saganspirit I can watch a lot of videos in 20 minutes and the vast majority of people on RUclips and on social media in general skip videos who are more than 10 minutes long
At least he started on the dot no rumbling or intros so you should highlight that. Some audiences actually have problems with short videos, they like longer videos. Jonas this was excellent ❤😊
Thank you for your information. I couldn’t agree more as my husband is “dealing with” prostate cancer and following the metabolic protocol. The only thought I’d add is, “Good luck finding an oncologist who believes in any of this mumbo jumbo!” I just walked out of our oncologist’s office a couple of weeks ago because of his mocking, knowing it all attitude. I will never return. Dr Seyfried is a hero and I pray that the medical world will wake up one day…but I doubt it.
I’m very sorry to hear that. This reaction of your physician is the reflection of the pharma industry. Oncologist should know that cutting out sugars and decreasing glutamine can be immensely helpful. I have a had patient that had done metabolic therapy in combination with high dose intravenous vitamin C weekly. He only required very low doses of chemo and for a short time only.
@@JonasKuehneMDWhere can someone get this treatment, metabolic therapy? Germany?
p.s. Can someone get vitamins C without glucose, fructose etc?
Great question.
Prostate cancer is very pernicious, the urologists are butchers, they use a meat cleaver when they should be using a scalpel. Prevention is key gotta drive insulin to baseline by going 0 carb, the continual insulin spikes over a long period of time are extremely dangerous and our urologists need to stress this but the will not because they benefit from our misery.
@@JonasKuehneMD2:51
Another reason to enjoy my daily cup of matcha!
Yes!!
Jonas thank you for your clear and thorough explanations. I understand that some folks consider that your presentations are too long but I very much appreciate the thorough descriptions of biochemical mechanism involved and scientific publication references.
Thank you so much! I always try to make the scientific background of a topic more digestible and present it in a way that makes sense to me as well.
@@JonasKuehneMD It does help in my understanding that I have a medical science background with particular interest in biochemistry and microbiology. My main interest is to help my partner who is in remission from breast cancer and my friend and former colleague who is stage 4 breast cancer in the lungs and about to restart treatment. I came across Dr Seyfried in my research but even though I understood what he was saying, it wasn’t convincing enough to share with folks without much basic background knowledge. By contrast your presentations are distilled and much easier to follow. Thank you!
@lucdelhaize4029 Please share your wife protocol to stay cancer free. I'm also breast cancer
Could you make a video about Berberine and one about Fenbendazole?
I'll show you in 1️⃣ what Burbon did for me 🤮
Suzanne Somers wrote books on Cancer. She had breast cancer. But cancer finally did kill her. So many studies are done and what works for some doesn't always work for others
That is very true. I think it’s important to attack the disease from different angles. Therefore, metabolic therapy, mixed with supplements like green tea or berberine is a good start.
I believe Suzanne summers lived 20 years with breast cancer. It's possible she would have died much sooner without her nutrition and natural remedies. I know several people who did not do chemo and other mainstream treatments and did alternate treatments. All have died but lived MUCH longer than the doctors said they would with regular treatments. My wife's grandmother was given maybe a year if she did surgery and chemo. She did natural stuff and nutrition and lived 7 years
@@kennygee2715 Suzanne sommers had done chemotherapy. There is no one shoe fits all. I know many people who done chemo and are living today a normal life, and others I know that died. Don't look one way when you cross the street you will certainly get hit by a car. All bodies need the right foods, exercise on a daily basis. Fruits vegetables, nuts and some fish and some meat limited. Science plays a very large role in our lives and so does nutrition. If it were not for the advancement of medicine we would not be living as long. I only look at facts not fiction
Thank you so much for posting reliable references to support your points. It is much appreciated.
Glad it was helpful!
Thank you for this essential information. I appreciate your thorough explanation. I did not think it was too long. 💞
Thank you!
Excellent video, i like your approach. i look forward to more of your videos.
Awesome, thank you!
@@JonasKuehneMD btw I just noticed you are from Los Angeles. I have a friend who has recently been diagnosed with leukemia last month and is now currently doing chemo and it's pretty brutal. Are there an doctors in Los Angeles area that you know of that specialize in treatment that doesn't involve chemo and instead targets diet and less harsh medications? She's only 43, but I feel like there are better options than doing just chemo. Thanks in advance
I’m so glad I found your channel today and without hesitation subscribed. 😉 I look forward to perusing your many videos. Curious if the Bigelow green tea is organic?
Thank you so much! Bigelow has an organic green tea, but it needs to state so on the package. They also have commercial non-organic green tea.
@@JonasKuehneMD Shouldn’t teas be organic due to pesticide contamination?
Many thanks for your explanation which can be understood
🙏❤️
Dr. Thank you so much. VERY good comprehensive video on EGCG.
To be clear, does EGCG prevent glutamine uptake into ONLY cancer cells? Or both normal & cancer cells? How would this effect recovery from exercise?
TYIA
EGCG decrease uptake by all cells. Healthy cells are not negatively affected by this, however cancer cell depending on glutamine fermentation are.
@@JonasKuehneMD okay TY!
Outstanding presentation!
Thank you kindly!
Thanks. Excellent information to consider.
What is the ideal amount of green tea per day? I drink 2 cups of organic oolong greent tea a day. Should i drink more. Cancer survivor, serious about preventing recurrences.
In Japanese studies, they found that drinking 10 or more Japanese sized cups per day Showed a significant decrease in cancer rates. You could also consider supplementing with EGCG at the dose recommended by the manufacturer.
🍵🤔
Matcha😊
1 green tea in the morning, one in the evening?
How much ECGC? When?
How much Berberine?
What do you think about Fenbendazol?
I cannot drink green tea in the evening due to the caffeine. I will have two green teas in the earlier part of the day.
How about the recommended dosages when you want to fight active cancer? I mean, at what dosages we are speaking about actively fighting cancer?
A common recommendation by the manufacturers for EGCG is 1800 mg of green tea extract daily which has 45% EGCG.
There is not much research on appropriate dosing, but in general, the manufacturers will push for the highest dose within safety margins to sell as much of the product as possible.
What type of green tea is better? Macha green tea, or Jasmine tea (green tea) & any green tea leaves?
Matcha appears to have a higher EGCG content, but also higher caffeine content
Thank you! ❤
@Dr Kuehne could you tell me how much EGCG I should take. I'm at the very beginning of my journey and havent even seen the oncology team yet. And should I take it intermittently?
I have not seen studies discussing the specific dose. Most manufacturers of green tea extract recommend 1800 mg daily, with 45% EGCG.
This is not medical advice, of course and you should always ask your physician first. In general, though this is a dose that can be taken daily.
Search cancer care by Paul Marik, he lists the best dosage. His paper is 227 pages, a lot of good information.
THANKS FROM AUSTRALIA
You are very welcome. Thank you for joining the channel from down under.
I wonder if a little is good, is more better? I drink white tea which is the white leaves of the green tea plant.
White tea is an excellent choice. Very high in antioxidants. As for green tea, the Japanese studies generally showed people drinking upwards of 10 small cups daily.
@@JonasKuehneMD wow I’d never get to sleep! lol maybe will look into supplementing with EGCG. Great channel!
Is it important that it says ECGC or just green tea? And how much coffee is allowed, I found capsules from maybe two manufacturers, so I'm wondering how important it is to look at. Greeting💝
*coffein in capsules
*EGCG😂
It should say EGCG as this is the active ingredient in green tea. 2-3 cups of coffee per day should be OK.
@@JonasKuehneMD thank you!💝
11:32 green tea blocking glutamine In combination RSO/FSO cannabis oil treatment and prevention spreads or reoccurrence?
8:28 does it pass the blood brain barrier to kill brain tumors and meningioma tumors??
From the international journal of molecular science:
Recently, in vitro experiments suggested that EGCG and its metabolites could reach the brain parenchyma through the blood-brain barrier and induce neuritogenesis. These results suggest that metabolites of EGCG may play an important role, alongside the beneficial activities of EGCG, in reducing neurodegenerative diseases.
Hi can you recommend a which green tea to buy
How much green tea do you need for it to become effective ?
It’s difficult to find exact doses in the literature. The study from Japan shows that 10 Japanese sized cups daily or more significantly lower risk of cancer. As it comes to EGCG supplements, most manufacturers recommend 1200-1800mg of green tea extract with 45% EGCG.
Thank you. I drink a lot of green tea already but that's probably a bit much. I think some form of supplement on top of this woukd probably help then
If I take 200mg-400mg per day, are my risk of liver issues are diminished?
I cannot give any medical advice on this platform. In my experience that is a reasonable dose
Can dialysis patients take this supplement with active cancer?
In my opinion yes, but you should discuss any supplements with your oncologist first.
Dr. Kuehne, is it true that when we eat carbohydrates, our need for vitamin B1 goes up?
Thiamine is needed in carbohydrate metabolism, so a certain daily amount is required.
@@JonasKuehneMD OK, thank you.
Is decaf green tea good
“Studies suggest that decaffeination can lead to a minor reduction in the levels of catechins and other antioxidants compared to regular green tea. While this decrease exists, decaf green tea still contains notable amounts of polyphenols and antioxidants, which contribute to its health-promoting properties.”
So glutamine supplement , for leaky gut, isnt a good idea, i take it.
Not necessarily. Your own body makes glutamine as it is a non-essential amino acid.
For leaky gut I would suggest a gluten-free diet and glucosamine supplement
I took it extensively ended up with colon cancer
Healthy but what about all the fluoride in EGCG?!
The amount of fluoride and green tea may be slightly higher than in black tea, but still very low, and in my opinion does not post a significant risk.
My oncologist won't hear of anything about glutamine blocking. he said don't waste your time. I am changing doctors. I am stuck taking prednisone and want to fast but he thinks I will do immunotherapy again so he is giving prednisone to manage the immune induced hepatitis. it isn't working. help I want to start a but take egcg again. I am trying to find a doctor on my plan that will allow this. Perhaps just drinking a few cups of green tea per day will help?
I’m sorry to hear about your experience.In my opinion EGCG and berberine, a ketogenic diet, as well as weekly high dose vitamin c iv therapy (if G6PD is normal) can work complementary with low dose chemotherapy. of course you need to discuss any diet, supplements, or other modalities with your treating oncologist to make sure it is safe for you.
@@JonasKuehneMD Thank you for that. Chemo means immunotherapy too yes?
Stop telling your Dr & drink what you Want: green tea all day!
For someone with oral cancer with no solid foods, is it hard to go on keto diet?
One of the issues is weight loss without adequate calories. It certainly can be done, but would need to be at least discussed with a treating physician. If soft foods and purees are OK, there are certainly some possibilities. Also, protein shakes with heavy whipping cream will be calorically very dense.
Thank you for your quick response and sharing your knowledge.
Scramble eggs ground beef,canned fish all sort I eat daily no teeth, if your unable at all many creams, oils could be drank
@@daleval2182 Thanks for sharing.
@@stanleyyu2079 I hope your recovering brother, I too am fighting the shit , it isn't easy I know, many days I just fast as it is no food for cancer, but when I eat only low low carb to feed my body from getting too weak , protein and healthy fat select green super foods ,
I love it BUT can we please start adding the fact that cancer cells can also survive on a ketogenic diet/ without glucose consumption?
They can adapt their metabolism to fit even ketones (I guess this is not true for all cancers, but still).
I always hear the basic point of "cancer eats glucose" but it's not that simple!
Still keto has many benefits.
You are correct, it is not that simple. The two main fuels of cancer cells are glucose and glutamine. The theory that cancer can evolve to feed on ketones has not been proven as far as I’m aware. This is because the mitochondria are defective in cancer cells. Fermentation seems to be the only way to generate energy.
NO Cancer can feed on ketones man wrong, it can't ferment it, not possible
Cite your research paper showing cancer uses ketones
@@nikesonmyfeet1234I worded it wrong but the point still stands. Cancer can survive on a keto diet. If it wouldn’t, everyone on keto would survive indefinitely which they don’t.
It’s not my duty to present papers for you. The fact I stated stands and that’s all I’m gonna say.
If you can’t work with that it’s your problem
@@LorettaBangBang Except for the fact that it’s not a fact.
You will get more views if you make your videos shorter. Good content
Thank you for the feedback. I agree, sometimes they get a bit longer. I usually opt for around 10 minutes but if it’s an exciting topic with a lot of information, I might run a bit longer.
It's only 20 minutes
@@saganspirit I can watch a lot of videos in 20 minutes and the vast majority of people on RUclips and on social media in general skip videos who are more than 10 minutes long
@@user-op4rv3zj4c Hard to believe that people used to spend hours reading books...........
@@user-op4rv3zj4c Hard to believe people used to spend an hour+ reading books.........
Thanks for the information, but please shorten your video to 10 minutes or less. No disrespect.
Appreciate the input!
At least he started on the dot no rumbling or intros so you should highlight that. Some audiences actually have problems with short videos, they like longer videos. Jonas this was excellent ❤😊
Perfect video in my opinion. 🙌 you just can't get the right information in tictok bites. 🤷🏼♀️
Very good input
Very informative foe people who are new to this! ❤