Minor correction, as it might cause confusion for some viewers -- alpha-ketoglutarate was mispronounced as "alpha-ketoglutaMate" (the "R" was erroneously replaced with an "M" when you were speaking). The text on the screen was correct, but the pronunciation was off. Just wanted to point that out in case anyone got a little confused.
You're the best prof! I like how you even include an easy chart at the end to have all of the individual reactions in order with their respective enzymes. Wish me luck on my biochem exam 😭
I graduate with my bachelor's in biology in 2 months and this is the bane of my existence! Although I've never really understood it until your videos! Thanks Bio Jesus!
Omg you literally saved me. I’m a pharmacy student and I was crying because I couldn’t understand a thing in biochemistry. Thank you so much for this video.
hey man photosynthesis is what welcomes us into biology. It will give us a nice hug, and as we tell it how easy it is, its friends glycolysis and krebs cycle will come and stab us from behind, then drag our dead body along with the thousands of other students murdered by them. but the professor dave is the one who stops them in the nick of time, with is unbreakable shield this is getting cringey ill stop
I was given this topic to report by my teacher and was really confused, out of all the videos I watched this one was the easiest to understand, thank you prof❤️
I feel your pain my friend. Got a biochem resit tomorrow and this stuff is going in one ear and out the other. Unfortunately I have to deal with this nonsense in order to eventually look down microscopes for a living.
big thanks :D, and heres a note. * I summed up all the CO2 from the three phases and got 4 CO2 (? uh, supposedly 6 CO2 in the Equation for Aerobic Respiration) 1 Glucose + 6 O2 → 6 CO2 + 6 H2O + Energy * for the sake of fixing this problem... I've found out something hidden: Transferring 1 Pyruvate to CoA gives 1 CO2 Molecule. * thus for 1 glucose = 2 Pyruvate, Krebs gives 4 CO2 (from main cycle) + 2*1 CO2 (from transfer to CoA) so 6 CO2.
Wow! The Krebs cycle looks scary at first, but you "break it down" (get it?) and cause it to present a much less daunting task. I have one question though. The Krebs Cycle is an aerobic process, but I didn't see any mention of oxygen in this video. When is O2 used, and where?
EpicSelenium34- Oxygen is consumed at the end of the electron transport chain during oxidative phosphorylation, when those electrons are passed to oxygen and H+ to form water. Oxygen is therefore referred to as the "terminal electron acceptor".
@@ProfessorDaveExplains Well, in 3:29 on the (2) Cellular Respiration Part 1: Glycolysis video you state that glycolysis is anaerobic, no O2 needed process.
@@ProfessorDaveExplains Thank you very much! I appreciate your reply and your videos! I really like that you go from the basics to more advanced information, like in the Glycolysis video, you first showed the basic scheme of what happens in that process and that there are 10 enzymes involved and then talked about the enzymes. THANK YOU for your biology videos!
So do you think the supplement Arginine alpha-ketoglutarate is healthy to take for increasing nitric oxide for people with high blood pressure and athletes? Or is it dangerous to overload the kreb cycle with alpha-ketoglutarate?
Plants did not evolve before aerobic respiration. The first organisms that flooded the world with oxygen were single cellular cyanobacteria, which lead to the Cambrian explosion. Plants evolved much later.
Why does when there is more concentration of ATP the citric acid cycle has a slower rate and when there is a low concentration of ATP, it has a faster rate?
I know this is late, but it's due to regulation in glycolysis. When there is a high [ATP], both phosphofructokinase (Fructose 6-Phosphate -> Fructose 1,6-BP) and Pyruvate Kinase (phosphoenolpyruvate -> Pyruvate) are allosterically inhibited by ATP. When there's high ATP, glycolysis is inhibited, and gluconeogenesis is promoted to form glucose. This usually happens in a fasted state
funny how these videos are already extremely condensed and shortened and i'm just gonna be taking 3 of them and condensing them even further into a 5 or 6 min video.
Minor correction, as it might cause confusion for some viewers -- alpha-ketoglutarate was mispronounced as "alpha-ketoglutaMate" (the "R" was erroneously replaced with an "M" when you were speaking). The text on the screen was correct, but the pronunciation was off. Just wanted to point that out in case anyone got a little confused.
Thank you
Not that big of a deal
Thank you
Apriga
Can someone tell me why it's called alpha ketoglutarate?
You're the best prof! I like how you even include an easy chart at the end to have all of the individual reactions in order with their respective enzymes. Wish me luck on my biochem exam 😭
good luck!
Indeed
I know it's been 2 years but how did your exam go?
@@chell6022 She dropped out and had 10 babies by a man named Jorgé.
@@_A.Trader About to take my biochem exam tomorrow, hopefully the same doesn't happen to me!
@@col-gz5tk 12 babies?
lol mate you're a legend, you managed to explain one lecture's worth of content in 5 minutes!!! Genius.
Indeed
I graduate with my bachelor's in biology in 2 months and this is the bane of my existence! Although I've never really understood it until your videos! Thanks Bio Jesus!
chem christ
Lol physics Jesus😂😂
Omg you literally saved me. I’m a pharmacy student and I was crying because I couldn’t understand a thing in biochemistry. Thank you so much for this video.
Thank you for that little history in the beginning. Really helped me understand the bigger picture.
You make biochemistry much easier , thank you 🌹
i like the color coding to separate different reactions.
Thank you for the subtitles! Helps a lot foreigners :)
Who tf can even memories these insanely difficult word 😢
For every word you don’t understand, try to search on Google “(word) etymology”. For example “hydrogen etymology”. I hope this helps. :)
I am just a kid in highschool trying to understand this. I just wanted to say photosynthesis is easier than cellular respiration.
hey man
photosynthesis is what welcomes us into biology. It will give us a nice hug, and as we tell it how easy it is, its friends glycolysis and krebs cycle will come and stab us from behind, then drag our dead body along with the thousands of other students murdered by them.
but the professor dave is the one who stops them in the nick of time, with is unbreakable shield
this is getting cringey ill stop
oh yeah go suck some sun then
Have you done the light and dark stages of photosynthesis
Thank you so much Prof. Dave, you give me hope that I might pass my exam
God damn I'm a physics student, never realised that so many reactions are taking place. Mind boggling.
I was given this topic to report by my teacher and was really confused, out of all the videos I watched this one was the easiest to understand, thank you prof❤️
These are so helpful for biology, thank you
I still dont understand this part of cellular respiration. Glycolysis is easy enough but this is just awful
I never should’ve become a stem major
I feel your pain my friend. Got a biochem resit tomorrow and this stuff is going in one ear and out the other. Unfortunately I have to deal with this nonsense in order to eventually look down microscopes for a living.
the acetyl CoA comes from the pyruvate oxidation,what about the oxaloacetate, where does it come from 💔?
Thank you for sharing your knowledge and for the taking the time to create these graphics!
The number of ATP produced when a molecule of acetyl coenzyme-A is oxidized through citric acid cycle is??????
Options...
A-12
B-24
C-18
D-15
Thank u thank thank u very much proff dave❤ was looking for a detailed video on everything about citric acid cycle with all the enzymes
I have an exam in. An hour.. You're a lifesaver prof
big thanks :D, and heres a note.
* I summed up all the CO2 from the three phases and got 4 CO2 (? uh, supposedly 6 CO2 in the Equation for Aerobic Respiration)
1 Glucose + 6 O2 → 6 CO2 + 6 H2O + Energy
* for the sake of fixing this problem... I've found out something hidden:
Transferring 1 Pyruvate to CoA gives 1 CO2 Molecule.
* thus for 1 glucose = 2 Pyruvate, Krebs gives 4 CO2 (from main cycle) + 2*1 CO2 (from transfer to CoA)
so 6 CO2.
very late reply but nice
Wow! The Krebs cycle looks scary at first, but you "break it down" (get it?) and cause it to present a much less daunting task. I have one question though. The Krebs Cycle is an aerobic process, but I didn't see any mention of oxygen in this video. When is O2 used, and where?
That's in glycolysis! Check out Part 1, the clip right before this one.
EpicSelenium34- Oxygen is consumed at the end of the electron transport chain during oxidative phosphorylation, when those electrons are passed to oxygen and H+ to form water. Oxygen is therefore referred to as the "terminal electron acceptor".
@@ProfessorDaveExplains Well, in 3:29 on the (2) Cellular Respiration Part 1: Glycolysis video you state that glycolysis is anaerobic, no O2 needed process.
Ooh yeah, I'm not sure what I meant by that super old comment. Molecular oxygen is the final electron acceptor in the electron transport chain.
@@ProfessorDaveExplains Thank you very much! I appreciate your reply and your videos! I really like that you go from the basics to more advanced information, like in the Glycolysis video, you first showed the basic scheme of what happens in that process and that there are 10 enzymes involved and then talked about the enzymes. THANK YOU for your biology videos!
So good! Subscribed
Thank you so much Prof 💙 God bless you more
Can god bless his own son?
You've been saving my ass since high school. Thank you, Chemistry Jesus
Thank god you made this explanation! I was really struggling with this!
Thank you professor
So do you think the supplement Arginine alpha-ketoglutarate is healthy to take for increasing nitric oxide for people with high blood pressure and athletes? Or is it dangerous to overload the kreb cycle with alpha-ketoglutarate?
Thank you so much
Thank you processed
ur description table is very helpful thank u sir
Pl explain carbohydrates metabolism all cycle
This is so hard but i managed to understand the it tysmm
Thank you
hello professor thank you for your efforts...Just a minor correction
STEP 7 - H2O is used up not gained
Thank u🙏
I call this guy “Biolo-Jesus”
Very beautifully illustrated
Endosymbiotic theory proposes that mitochondria were once a separate organism
Plants did not evolve before aerobic respiration. The first organisms that flooded the world with oxygen were single cellular cyanobacteria, which lead to the Cambrian explosion. Plants evolved much later.
You are a lifesaver!!
Are prof Dave's explainations too advanced for highschool? Where can I find it simpler?
you're awesome thank you so much for these videos
Why does when there is more concentration of ATP the citric acid cycle has a slower rate and when there is a low concentration of ATP, it has a faster rate?
I know this is late, but it's due to regulation in glycolysis. When there is a high [ATP], both phosphofructokinase (Fructose 6-Phosphate -> Fructose 1,6-BP) and Pyruvate Kinase (phosphoenolpyruvate -> Pyruvate) are allosterically inhibited by ATP. When there's high ATP, glycolysis is inhibited, and gluconeogenesis is promoted to form glucose. This usually happens in a fasted state
funny how these videos are already extremely condensed and shortened and i'm just gonna be taking 3 of them and condensing them even further into a 5 or 6 min video.
I think you forgot to put the CO2 as a product from the cribs cycle
it's all in there
3:38 is the summary
Once again, Thanks Chemistry Jesus❤️
100 level of medical school: can professor dave save it😂
Bless you
Every source has different number of total atp
At 2:00
appreciated if you could remove initial troublesome sound.
1:55
Endosymbiotic theory
1:10
شرح رائع
I love you 💓💓💓
amen jesus
Thank you
Thank you professor...