I'm a post doc virologist and since I was just starting the basics I already watched your lessons. I envy your students!! I wish I could go back in time and be your student!
The last question of the series. You asked what statements are true about RNA genomes, and stated that the answer "(+)ssRNA virus replication cycles do not require a (-) strand intermediate" is false. I'm confused - I thought the + ssRNA is ready to be translated by the ribosome upon cell entry? What's the intermediate business? I replayed the video segment a few times. I guess I'm dense, I can't figure it out.
I believe what your thinking of is answer A +ssRNA genomes may be translated to make viral protein. Which is true and is the answer, mRNAs make protein. The answer your confused with is if an intermediate -ssRNA is not required in the REPLICATION CYCLE, Vincent right after says "they do, how else will you get to more plus strands?" The negetive strand intermediate is needed for plus strand replication. I hope I helped. :)
So helpful for my vet lab procedures. I'm an undergraduate in animal sciences and genetics. Still don't get the Baltimore system but will work through it slowly.🤗🤗🤗🍷🍷🍷🍷⚗️💉👩🏽🔬🕵🏾♀️
I am aware that the canonical literature on the matter acknowledges the disambiguity of whether viruses are living beings or not. So, in a sense, my answer is right there and there's nothing further to look into. Yet, the study of viruses is included in the field of biology. Which is a set of rules, adhering to the scientific method, used in the study of living beings. Could we argue that? Perhaps we could. If we did, the case of viruses would be the perfect place to start. Every living being is subject to entropy. The Universe itself is subject to entropy. It expresses itself in an infinite number of ways all the time everywhere we look. For instance, in a species of living beings like humans it expresses itself through all the minute genetic variations that exist practically between every individual in our species. Notice that in this case entropy does not necessarily carry any negative connotations, as it usually does, but that is beyond the scope of my current argument, as well. For all we know, these variations don't exist in individual virions. Mutations do occur, but everytime that happens, a new species emerges and it co-exists peacefully with all its ancestral species! With all other species of viruses, actually! Indeed, they flourish, as long as the resources necessary for their reproduction are in abundance. Which, since viruses seem to infect everything that biology classifies as living, is business as usual for those viruses. I believe at this point we would be excused to assume that as far as living beings go and to the best of our understanding, viruses are... perfect! Well, perfect is a human term and as such is subject to all the misinterpretations that arise out of the diversity, or should I say, entropy of our species. I would like to know what a virus' opinion on the matter would before I carry my hypothesis any further.
I'm a post doc virologist and since I was just starting the basics I already watched your lessons. I envy your students!! I wish I could go back in time and be your student!
completely agree with you.
As a PhD student in the field of virology, I must say , I wish you were my professor
I'm really disappointed with what I learned on my Msc, your lectures are just what I needed. Thanks for sharing your knowledge!
The last question of the series. You asked what statements are true about RNA genomes, and stated that the answer "(+)ssRNA virus replication cycles do not require a (-) strand intermediate" is false. I'm confused - I thought the + ssRNA is ready to be translated by the ribosome upon cell entry? What's the intermediate business?
I replayed the video segment a few times. I guess I'm dense, I can't figure it out.
I believe what your thinking of is answer A +ssRNA genomes may be translated to make viral protein. Which is true and is the answer, mRNAs make protein. The answer your confused with is if an intermediate -ssRNA is not required in the REPLICATION CYCLE, Vincent right after says "they do, how else will you get to more plus strands?"
The negetive strand intermediate is needed for plus strand replication.
I hope I helped. :)
@@Anonymous-bg2cx Absolutely did. Thanks!
@@theblackout27 I'm so glad, best wishes.
could u please tell me more deatils about the book fever because i want to read it
So helpful for my vet lab procedures. I'm an undergraduate in animal sciences and genetics. Still don't get the Baltimore system but will work through it slowly.🤗🤗🤗🍷🍷🍷🍷⚗️💉👩🏽🔬🕵🏾♀️
That makes two of us. Good luck Zaimah!
How does the genome control the “timing” of the replication cycle? This is something I can’t understand
Very informative lectures..I am enjoying .
Thank you for the lectures Dr. Racaniello. So, the flu shot would not really work?
A kitchen blender as a research tool wow, that is inventive.
I am aware that the canonical literature on the matter acknowledges the disambiguity of whether viruses are living beings or not. So, in a sense, my answer is right there and there's nothing further to look into.
Yet, the study of viruses is included in the field of biology. Which is a set of rules, adhering to the scientific method, used in the study of living beings. Could we argue that? Perhaps we could. If we did, the case of viruses would be the perfect place to start.
Every living being is subject to entropy. The Universe itself is subject to entropy. It expresses itself in an infinite number of ways all the time everywhere we look.
For instance, in a species of living beings like humans it expresses itself through all the minute genetic variations that exist practically between every individual in our species. Notice that in this case entropy does not necessarily carry any negative connotations, as it usually does, but that is beyond the scope of my current argument, as well.
For all we know, these variations don't exist in individual virions. Mutations do occur, but everytime that happens, a new species emerges and it co-exists peacefully with all its ancestral species! With all other species of viruses, actually! Indeed, they flourish, as long as the resources necessary for their reproduction are in abundance. Which, since viruses seem to infect everything that biology classifies as living, is business as usual for those viruses.
I believe at this point we would be excused to assume that as far as living beings go and to the best of our understanding, viruses are... perfect!
Well, perfect is a human term and as such is subject to all the misinterpretations that arise out of the diversity, or should I say, entropy of our species. I would like to know what a virus' opinion on the matter would before I carry my hypothesis any further.