@@Theriodontia4945 yeah but i mean if its just some synthetic thing we made we would eliminate some sickness for a amount of time and then everything would go back to normal right? like what are the long term consequences of over using a antibiotic besides not being able to use it?
@@Theriodontia4945 But that gives time for phages to evolve and find a way to get rid of anti-crispr. That's the reason why if the bacteria is resistant to a phage, then it will not be resistant to a drug, and if the bacteria is resistant to a drug, it will not be resistant to the phage.
I thought the point of phage therapy was to get around the fact Bacteria can evolve around the relatively limited number of amtibiotics we have. There is many many more Bacteriophages variants then there are antibiotics.
I work in hospitals in a clinical setting and am very interested in infectious diseases but I have relatively little knowledge in microbiology that doesn't relate to the practical aspects of treatment. It's very interesting to me that Pseudomonas has multiple mechanisms for adapting against bacteriophages! In the clinical setting Pseudomonas has a reputation of being an extremely difficult bug to kill, which can adapt very quickly and acquire many antibiotic resistances. It's fascinating that this doesn't only apply to humans trying to kill it, but viruses too! Very glad I discovered this channel I will be watching more of your videos, they're a great balance of depth & simplicity of presentation
Why using thinning hair scissors in your images? Why have the needless, “there is no God” statement? Do you have too many views, so you are inserting your theological views, making those with different views feel excluded? Nice inclusion move. Let me help you with another example. Should the frame about the Mona Lisa contain a Bible reference or, “Thanks to God this was created?” These might more fully represent the painter’s theology. Perhaps best to create for the whole world.
The “there is no God” line means “No God will save you,” thanks to God’s depiction has a largely forgiving figure. And kind of ironic that you made satire of yourself in your own statement. After all, the Mona Lisa’s creator, Leonardo Da Vinci, was a catholic Christian, and this is pretty much proven by all the thousands of Christian Art pieces he’s made in his lifetime. And why are you claiming exclusion when Christianity is so embedded into society that it is literally the root of how way say goodbye? “God be with ye” and all that. What about the fact that many politicians across history love to use the Bible as a political tool for their personal gain, a bit of an ironic move. It is exactly how the crusades started, and was also leveraged by the late dictator Francisco Franco in living memory. Less… vicious ways it has been used is in Victorian society, famously as strict as it was Christian and as Christian as it was ruthless (more sweet sweet irony, hooray), most of the population from the poor child coal miners to the rich aristocrats and factory owners were all Christian. Also the fairly common name Christian has the same root as the name of Christianity’s followers, derived from Christianus aka “follower of Christ”
The “there is no God” line means “No God will save you,” thanks to God’s depiction has a largely forgiving figure. And kind of ironic that you made satire of yourself in your own statement. After all, the Mona Lisa’s creator, Leonardo Da Vinci, was a catholic Christian, and this is pretty much proven by all the thousands of Christian Art pieces he’s made in his lifetime. And why are you claiming exclusion when Christianity is so embedded into society that it is literally the root of how way say goodbye? “God be with ye” and all that. What about the fact that many politicians across history love to use the Bible as a political tool for their personal gain, a bit of an ironic move. It is exactly how the crusades started, and was also leveraged by the late dictator Francisco Franco in living memory. Less… vicious ways it has been used is in Victorian society, famously as strict as it was Christian and as Christian as it was ruthless (more sweet sweet irony, hooray), most of the population from the poor child coal miners to the rich aristocrats and factory owners were all Christian. Also the fairly common name Christian has the same root as the name of Christianity’s followers, derived from Christianus aka “follower of Christ”
Imagine an antibiotic that disables crispr to make bacteria vulnerable to phage therapy.
And then the bacteria eventually evolve a resistance to that specific antibiotic. Be careful about using antibiotics.
@@Theriodontia4945 yeah but i mean if its just some synthetic thing we made we would eliminate some sickness for a amount of time and then everything would go back to normal right? like what are the long term consequences of over using a antibiotic besides not being able to use it?
@@Theriodontia4945 But that gives time for phages to evolve and find a way to get rid of anti-crispr. That's the reason why if the bacteria is resistant to a phage, then it will not be resistant to a drug, and if the bacteria is resistant to a drug, it will not be resistant to the phage.
I thought the point of phage therapy was to get around the fact Bacteria can evolve around the relatively limited number of amtibiotics we have. There is many many more Bacteriophages variants then there are antibiotics.
This is amazing! I am sharing this with every biology teacher I know and all of my students. Please, keep making these awesome long form videos!
That's awesome! It means a lot. What do you teach?
I tutor in biology and chemistry, and kids will be so excited to have more fun videos for review.@@phylumchannel
I would love to know what they think!
Anti-crispr should have been named Soggifier or something lol
This channel is absolutely underrated
I work in hospitals in a clinical setting and am very interested in infectious diseases but I have relatively little knowledge in microbiology that doesn't relate to the practical aspects of treatment.
It's very interesting to me that Pseudomonas has multiple mechanisms for adapting against bacteriophages! In the clinical setting Pseudomonas has a reputation of being an extremely difficult bug to kill, which can adapt very quickly and acquire many antibiotic resistances. It's fascinating that this doesn't only apply to humans trying to kill it, but viruses too!
Very glad I discovered this channel I will be watching more of your videos, they're a great balance of depth & simplicity of presentation
Love to hear that! Always good to hear from the medical community!
Just found the channel , and love it!!!
this channel is my new favourite channel
Yeah, there's a shit ton of Undertale genocide references in here...
another fire video 😈😈
Great stuff
Then us, using antibiotics for the most part
Old neutrophil on Fire whirl talking to little stem kids
underrated af
That atheist bacterium is very misinformed.
Why using thinning hair scissors in your images? Why have the needless, “there is no God” statement? Do you have too many views, so you are inserting your theological views, making those with different views feel excluded? Nice inclusion move. Let me help you with another example. Should the frame about the Mona Lisa contain a Bible reference or, “Thanks to God this was created?” These might more fully represent the painter’s theology. Perhaps best to create for the whole world.
Ah, I always like the smell of butthurt theists in the morning.
The “there is no God” line means “No God will save you,” thanks to God’s depiction has a largely forgiving figure.
And kind of ironic that you made satire of yourself in your own statement. After all, the Mona Lisa’s creator, Leonardo Da Vinci, was a catholic Christian, and this is pretty much proven by all the thousands of Christian Art pieces he’s made in his lifetime.
And why are you claiming exclusion when Christianity is so embedded into society that it is literally the root of how way say goodbye? “God be with ye” and all that. What about the fact that many politicians across history love to use the Bible as a political tool for their personal gain, a bit of an ironic move. It is exactly how the crusades started, and was also leveraged by the late dictator Francisco Franco in living memory.
Less… vicious ways it has been used is in Victorian society, famously as strict as it was Christian and as Christian as it was ruthless (more sweet sweet irony, hooray), most of the population from the poor child coal miners to the rich aristocrats and factory owners were all Christian.
Also the fairly common name Christian has the same root as the name of Christianity’s followers, derived from Christianus aka “follower of Christ”
The “there is no God” line means “No God will save you,” thanks to God’s depiction has a largely forgiving figure.
And kind of ironic that you made satire of yourself in your own statement. After all, the Mona Lisa’s creator, Leonardo Da Vinci, was a catholic Christian, and this is pretty much proven by all the thousands of Christian Art pieces he’s made in his lifetime.
And why are you claiming exclusion when Christianity is so embedded into society that it is literally the root of how way say goodbye? “God be with ye” and all that. What about the fact that many politicians across history love to use the Bible as a political tool for their personal gain, a bit of an ironic move. It is exactly how the crusades started, and was also leveraged by the late dictator Francisco Franco in living memory.
Less… vicious ways it has been used is in Victorian society, famously as strict as it was Christian and as Christian as it was ruthless (more sweet sweet irony, hooray), most of the population from the poor child coal miners to the rich aristocrats and factory owners were all Christian.
Also the fairly common name Christian has the same root as the name of Christianity’s followers, derived from Christianus aka “follower of Christ”
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