In the last problem, why wouldn't the electrophile react with the carbon bound to oxygen and nitrogen? Since in that case there would be more electronegative atoms pulling charge away from the carbon.
Really like the simplicity! However, I didn't hear you discuss steric hindrance of electrophilic reactivity (aldehydes = least hindered and most kinetically favored/strongest) or resonance stabilization of your formal charges. Thanks!
i got so tired of reading jack westin/shem for months and my eyes were kneeling over. really nice to watch videos, and to have something as clear cut as this
Do you mean would the oxygens around the phosphate block any nucleophile from being able to react with the phosphate? If that’s what you mean then I can tell you that nucleophiles are able to reach the phosphate, and this type of reaction is very common (for example adding nucleotides to DNA and RNA, hydrolysis of ATP etc)
As a 'rule of thumb' you might consider working on losing that phrase from your vocab. Etymology aint pretty (max size of stick youre allowed to beat your wife with = width of your thumb = rule of thumb). Amazing content and cant thank you enough for sharing! By all means, use the phrase. I just know that when I found out what the og rule of thumb was, it stopped feeling right when it slipped out. hard one to lose.
dude I wish I was as passionate about organic chem as you. thought you were going to cry a few times. Love the enthusiasm - video was very helpful!
best MCAT channel out there
This helped SOOO MUCH please keep up the good work!!!
In the last problem, why wouldn't the electrophile react with the carbon bound to oxygen and nitrogen? Since in that case there would be more electronegative atoms pulling charge away from the carbon.
Really like the simplicity! However, I didn't hear you discuss steric hindrance of electrophilic reactivity (aldehydes = least hindered and most kinetically favored/strongest) or resonance stabilization of your formal charges. Thanks!
i got so tired of reading jack westin/shem for months and my eyes were kneeling over. really nice to watch videos, and to have something as clear cut as this
I love the thorough explanations! 😂 🎉 ❤
dude.. thank you
Thank you for the video
wow thank you so much!
thank u very much
SO HELPFUL :))
Your thumbnail has them backwards…
I’m utterly shocked I missed that, thank you!
youre the bestest
Wouldn’t that phosphate group be sterically hindered so it wouldn’t even react or am I tripping
Do you mean would the oxygens around the phosphate block any nucleophile from being able to react with the phosphate? If that’s what you mean then I can tell you that nucleophiles are able to reach the phosphate, and this type of reaction is very common (for example adding nucleotides to DNA and RNA, hydrolysis of ATP etc)
@@sciencesimplified3890 yes that’s what I meant. Thank you for clarifying that!
good material, but I hope you are not having a stroke
thnk u u u u u u u u u uu uu
Too noisy 😊
As a 'rule of thumb' you might consider working on losing that phrase from your vocab. Etymology aint pretty (max size of stick youre allowed to beat your wife with = width of your thumb = rule of thumb). Amazing content and cant thank you enough for sharing! By all means, use the phrase. I just know that when I found out what the og rule of thumb was, it stopped feeling right when it slipped out. hard one to lose.