Tumor necrosis factor-alpha (TNF-alpha) Mnemonic for USMLE

Tumor necrosis factor-alpha or TNF-alpha for short, is a cytokine secreted by macrophages. TNF alpha signaling causes acute inflammation and fever, both of which help protect the body from infection. Importantly, tnf alpha signaling is also involved in the pathogenesis of Paraneoplastic cachexia. Lastly, tnf alpha signaling is targeted by anti-inflammatory biologic drugs like adalimumab and etanercept, which have the side effect making us more prone to infections like TB.
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[@rosestar4374]

Excellent. I am a physician. The next time I prescribe a tumor necrosis factor inhibitor medication I will refer my patients to watch this video

[@shobalmani1]

Humorous and easy to remember. Very nicely done. Thank you.

[@travettedaniel3708]

This was awesome!! Thank you!

[@saharbgh6725]

Thank you a lot! This was very helpful

[@user-te9vf3lh4q]

Thank you a lot ))!!!
I wanted add some other information about that factor : TNF-a also released by adipocites and makes nearly stayed aditocites less receptive for insulin (paracrine effects). And it afterward makes help for fat-mobilization . Simply , TNF-a in this case not seen like inflamatory factor , but regulator of fat levels in the adipose tissue

[@orewatalitonu358]

Thanks for this. Very helpful.

[@t-thevil2256]

Thank you so much sir!!

[@rub9729]

❤️great!! thx!!!

[@upoma028]

Thanks a bunch

[@dr.marialemesheva9312]

This is genius!

[@blacknoir4711]

Brillaint

[@drkishwerjabeen5582]

Thanks 🎉🎈🎈

[@sivasundaram781]

great

[@mirzasikandar1680]

Genius

[@nikhileshkorada9941]

First time first comment
Nice one 😅

[@copisetic1104]

DMSO also controls tnf-a

[@RedRedux]

Missed a drug: Rupatadine targets TNFA1 and PAF

[@robertcasey1708]

I hate this crab

[@guacamolegoblin]

What the fuck is a tnf?

[@yarakat6937]

Prima

[@michaeljohnramos1609]

Fk4icyr