Giant cell lesion Bone

[@manpreetkaurbasra1905]

Gc rich bone lesions
*Gct
*Gc rich OS
* Gc rich reparative granuloma
*Aneurysmal bone cyst
*Chondroblastoma

[@pathologytutorials007]

We can categories Giant cell lesions of Bone as
1) Reactive - Giant cell reparative granuloma, Brown tumor, Tubercular osteomyelitis, Myositis ossificans
2) Benign - GCT ,Chondroblastoma (CB), Non Ossifying Fibroma (NOF), Chondromyxoid Fibroma(CMF), LCH, BFH
3) Malignant -osteosarcoma, chondrosarcoma (clear cell variant),

[@pathologytutorials007]

Ohh I missed ABC under benign lesions

[@manpreetkaurbasra1905]

Diffrnc between GCT and GC OS on IHC
*HG34 expression*
+ In GCT
- In GC rich OS

[@milind4utube]

Osteoclastoma

[@milind4utube]

Giant cell bone tumour