Kevin Stone: The bio-future of joint replacement
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- Опубликовано: 22 июл 2010
- www.ted.com Arthritis and injury grind down millions of joints, but few get the best remedy -- real biological tissue. Kevin Stone shows a treatment that could sidestep the high costs and donor shortfall of human-to-human transplants with a novel use of animal tissue.
TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes. Featured speakers have included Al Gore on climate change, Philippe Starck on design, Jill Bolte Taylor on observing her own stroke, Nicholas Negroponte on One Laptop per Child, Jane Goodall on chimpanzees, Bill Gates on malaria and mosquitoes, Pattie Maes on the "Sixth Sense" wearable tech, and "Lost" producer JJ Abrams on the allure of mystery. TED stands for Technology, Entertainment, Design, and TEDTalks cover these topics as well as science, business, development and the arts. Closed captions and translated subtitles in a variety of languages are now available on TED.com, at www.ted.com/translate. Watch a highlight reel of the Top 10 TEDTalks at www.ted.com/index.php/talks/top10 
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Get this procedure covered by my national health care!!!
Great talk
A very interesting talk. I like your nomenclature for the GAL antigen enzymatic removal process. Somewhere I have a book on genetics and morphogenesis. I think it would be incredible if scientists someday discovered a biochemical process to program human stem cells to grow into complete and specific body part replacements, in some kind of incubator, without having to replicate the entire organism (clonal donors) and thus avoid the problem of having to sacrifice a complete organism in order to repair a pre-existing one. It is enigmatic how a single cell can divide, alter to a specific functional tissue type, and self-assemble into a complete, highly-organized and interdependent, interconnected and yet unique organism, based only on the sequence of base pairs on a very large organic molecule and the protein synthesis mechanisms and metabolic energy pathways of that original cell, with merely the addition of fairly simple raw materials, fuel, and oxygen.
ascbio.com
Holy shit, i was astounded by the rolex commercial xD
arthritis for you sir xD
If a wild pack of starving dogs ran into you in the woods they wouldn't think twice about eating you. A cow isn't going to help you find food if you were staving. A pig doesn't care if you have no where to sleep at night. Animal rights activist need to keep this in mind when they invest their time and money into saving animals. Please leave this doctor alone and let him do his research. He's on the path to helping millions of people around the world.
ted educates me better than school ever did.
@lukeism2 very good school, even better ted talks.
@SuperiorApostate To some extent, I agree with your comment. I myself, am a physics and math double major and most of us spend our time self-studying material ahead of what we're currently learning in our lectures. It's hard to get a good teaching system in countries that have a large GDP for capita since all the potential good teachers end up in other fields and it is more difficult to have well paid teachers.
Bravo!
@vladibo88 Agreed, but with the mass demand on the meat market, i'm sure there will be more than enough inventory to go in someone's joints rather than another's mystery meat hot dog.
@BrokenBjartur The function of a school isn't necessarily to educate its students, but rather to record that a student, perhaps, has some mastery of the material which they have studied formally. Also, major research colleges definitely work like corporations where they're looking for what benefits them the most, as opposed to their customers(the students). It's all about the research grants and funding.
this in what i need for my knee its mest up and hurts whenver i go 90 degress
Woah, they don't hold back on content do they? =D Thanks TED!!
Well placed humor.
@Darvinisti You said that in a James Earl Jones voice, din'cha? ;)
@didjabringadidjalong Yeah…I was surprised at the lack of thumbs down just because of that aspect of the talk.
@Live414 Don't forget injury. Tibial plateau fracture in my case.
@didjabringadidjalong Yeah, I never could figure out why they treat them the way they do.
@BrokenBjartur what i said was purely subjective from the start.
@SuperiorApostate LOL…nice comparison especially since they name the clock after sea creatures like oyster.
@DeepDuh you'd like how much of the animal the inuit eat. IT is good to use as much of the animal you can
@SuperiorApostate I was thinking the same thing. Who goes down to 12,000ft on a regular basis without a submarine?
Why has these procedures not gone wildly applicable in meniscus transplantation and knee implants. ???
@BrokenBjartur i learned to read and write before i started school. and ive learned a lot more about language from teh interwebz than from school.
and i didnt learn any of that shit u listed, from school.
@DeepDuh what if you use parts from an animal that is going to eaten for food
@SuperiorApostate Pigs are pretty smart. They have performed as well as Apes and dophins in mirror self-recognition tests. But ultimately we don't know to what extent they are aware of their surroundings.
arthritis ruins more lives, what about the families of those who die of cancer? id say that it does physically maybe, but certainly not mentally!
when he talks about taking tissues from cows and pigs I can't help but think about South Park. I'm not a particular animal lover, but I think synthetic grown tissue is the way of the future instead of (ab)using animals for anything else but nurriture. having said that, technologies like he discribes are a good way to fill the gap until we can do it all in a synthetic way.
@volound tell me about it
@defect530 I think dentist is still important in its aspect
@volound high school ?
@Saktoth It's really hard to argue about animal ethics, basically because animals can't stand in for their own rights. for me, the difference between using animals for food or for hightech medicine is: food is one of the most basic things we need for live. this still holds for meat and also for milk. not all of the components are replaceable by vegan food. I respect animals in a way, that I can only accept them to be killed for my sake if absolutely necessary (I don't apply that to insects btw)
@Saktoth Don't understand me wrong though: I still think it's ok to use animals for things like basic testing of medication (because otherwise you would put humans on a high risk) or even what is proposed in this video. I just think, that we should head towards a society, where this isn't necessary anymore (through science and technology, not through denying those activities).
Will this work for the great toe joint?
Bella Rose of course, that is why he is researching to help joints n pain individuals like you n me!
Sounds like a nice way to help all those who can afford it become younger, does it harm the animals because I thought in general we were heading away from animal testing?
Human lives are more important, and as he said animals provide a nearly infinite resource.
3D tissue printing is already a thing. Dr Stone, can you comment on how you might envision using 3D tissue printing to replace failed human tissue? Also, thank you for all your innovative work.
@Saesegral Not you, clearly. Which I dare say proves my point.
@volound can't give you enough thumbs up for your comment.
What i learned from this: Buy Rolex watch. Rolex is great and has a great history.
Finger Tapper beyond your pay scale homerun ...I.
@bladedaemon666 Gulp gulp, oh no I'm drowning, I wonder what time it is...
6:16 "or more talks" lol
@duca269 Now you just have to maintain you health till the the future.
If you're rich you can be healthy. Otherwise, go elsewhere with your broken knees.
@Mygo666 Men know what a rolex is .......you'll understand
@kokofan50 then I would be completely fine with it, it's always best to use as much as possible of an animal that is going to be killed anyway. I'm astonished at how good the japanese are at that through their cuisine btw. (despite being highly industrialised as well).
@jimius plus the pigs taste good, painkillers don't :p
But...but I WANT bionic limb replacement!
...you'd think the username would be a clue! :D
So...what is in for the pigs? :D
@Saktoth a) yes I meant nutrition. Sorry, I'm not a native english speaker. b) factory livestock - not in my country (switzerland). it's one of the reasons why I would have a hard time living in the US, despite that I like american culture - the food is just distasteful from all I hear.
@t3tsuyaguy1 Yup...there's that too.
@DrQuijano
Ditto.
Well we use heart valves from pigs and cows..
how close are all the ted talks to reality now? the recent one on wikileaks obviously is close to a conventional reality but what about these science ones?
Growing your own little cartilage în lab, don't need donor animal or other human
Rolex is resorting to classy words, big numbers, and most of all nostalgia.
Ok, but what will happen with the young healthy pig???
@BrokenBjartur Everyone can lay down the groundwork. Schools just try to force you into studying useless shit and it makes it hard for you to study what you actually want. Schools are the killers of motivation. It's funny how the best students in our class barely studied at school and did most of their studies at home and the student in our school who passed exams with highest scores was homeschooled. I myself learned english watching TV and was way better at it then my classmates.
@countryroo123 or they are trying to sell those to octopuses who do have 8 "arms"..
market ready by 2079.
i can understand why you would make a watch that can stand 12800 feet of water pressure, but I don't understand who would buy that. A person at that depth would immediately get crushed.
The Rolex Oyster 1926, The Oyster Perpetual 1931, Datejust 1945, Submariner 1953, Day-Date 1956, Deep Sea Special 1960, Sea-Dweller 2000 1967, Last Time Anyone Gave a Shit About Rolex 1980.
I mean seriously... it's a friggin' watch. This after someone talks about something as cutting edge as quantum physics or the future of joint surgery... oy.
@1schwererziehbar1 ill be 87 or 88, awesome.
So, do I get the bacon from my pig-lig donor too?
Lol
@vladibo88 What's not humane about killing animals?
all these medical innovations and going to the dentist is still like being kicked in the balls. maybe worse.
@funkalunatic: vegetarians use to make one mistake... they forget, that thinking doesn't prevent one from drawing wrong conclusions.
if eating animals is unethical, beeing human is unethical.
...11 years ago ...and no improvement since
the commercial at the end... rolex...
who "uses" wristwatches anymore? the brand rolex has become an accessory that shows off only wealth that they are meant for mermans who live 35.000 ft
@duca269
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Smoke & drink away!
Not hardware...
Not software...
It's bioware (lawsuit pending from actual hardware company)
I'm so sick of people using killing animals to fix humans. Why can't we grow body parts? Killing a pig or cow to make someone walk is really sad to me.
Do people still question why Aliens would obduct us and mutulate us for tissue?
Okay that's great, but in this economy, with our current Health care this becomes meaningless.
One thing that really irks me about animal rights activist is that on the way to their animal rights activist meeting they will walk over the homeless guy or turn their head at the homeless person holding a sign at the red light and not even think about helping those people. There are so many human beings in the world that are suffering and need help. I care more about human beings than I care about animals because animals don't are about us.
You are so naïve, how wrong you are ,people only take from you whatever they can use and when you don’t have anymore to give ,your obsolete, don’t put animals and people in the same category, you will be offending the animals
Humans are animals, your statement doesn't make any sense.
@heethen1 We take their meat, and now we take their ligaments and intestines as well. Useful little buggers. And tasty.
@BrokenBjartur I'll give you a big LOL for that statement. And a BIG ROTFLMAO if you believe it.
@purefunguy -_-
Alright let's buy a $2000 watch to dive in water with it. kkkkkk
@BrokenBjartur Well, education in Lithuania is useless all together because it's not acknowledged anywhere else in the world. At least not in the countries that matter and here, specialist get paid barely to survive so they leave to do shitty jobs in other countries or get an education there.
i just want awesome robot legs :,(
Lol
Why oh why did he call it... 'Bioware'? Bioware (game company) is horrible!
@shintsu01 Rolex. Waterproof down to 12,800 feet below sea level. For the man who will one day find himself that far beneath the ocean, and somehow still be alive ^.^"
i want a ROLEX
@BrokenBjartur Schools don't teach you shit, compared to the internet.
Sweet.
Though there is a good idea, when it comes to prevention: Chuck your shoes, and go barefoot. (this is based on science. Google it, if you doubt me)
THIS IS TO ALL THOSE BITCHES CRYING ABOUT HOW WE ARE USING ANIMALS
sure these animals are pretty smart and such and such and we shouldnt be doing it, but we already use them for meet, i mean we arnt killing an entire animal for one small part of it, these animals are already going to be dead for our food, we are just taking something extra from the carcess
lol bioware
I would totally lay that centaur chick.
when pigs fly
smells like teen
@volound shit school?
@SuperiorApostate @shallbeagain You would rather a person suffers and has a shitty life which he is able to comprehend and be aware of than a pig being killed to ease his life. Plus, there are a lot of people suffering right now(from a lot of things) and I do not see you doing anything for them therefore I conclude you care more about animals and not humans.
@DeepDuh
You dont need factory farms. Cows only produce milk if they have a calf, which is then killed. The sound a cow makes mourning their lost child is the saddest noise you will ever hear. Dont tell me Switzerland has no milk. :P
Worrying about the suffering of a few medical animals is ridiculous. A new joint can improve someones life by a lot more than a bit of nutrition will. And far fewer animals will suffer for a joint replacement than will suffer from a lifetime of eating them.
@bathetcnow go live in the wild and stop using the internet then.