The BIOPHAGE Pathogen in The Callisto Protocol Explained | Biophage Origins and Lore Explored

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  • Опубликовано: 18 янв 2025
  • Viruses are strange creatures. Bordering between life and non life, depending on who you ask, you'll get completely separate answers on what these things are. With that said however, they have a tendency to want to attack cells and change life to a way that benefits them, and not so much anything it infects. on the moon Calisto, there appears that ancient life at one point, evolved there. However, once the moons oceans were infected with a mystery biophage, things took a turn towards rapid evolution. In todays episode, we will discuss how that happened and ultimately, how it took place!
    Thank you for watching Roanoke Gaming and I hope you enjoy The BIOPHAGE Pathogen in The Callisto Protocol Explained | Biophage Origins and Lore Explored
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Комментарии • 1,2 тыс.

  • @MrArkangel11
    @MrArkangel11 2 года назад +1735

    Turning into liquid Roanoke

    • @RoanokeGaming
      @RoanokeGaming  2 года назад +273

      The ultimate storyline 🤣

    • @alexandarcecil8212
      @alexandarcecil8212 2 года назад +26

      Hey Roanoke what about if the person’s immune system is to strong and naturally handles viruses very easily and quickly to the point where something like coronavirus is overcome with in a time period of one week and after that the virus is completely gone and the body is not damaged in any way!?.

    • @B_4035mn
      @B_4035mn 2 года назад

      @@alexandarcecil8212 According to this, if they got this virus and fought it off completely, they would have permanent physical and mental disabilities, would still be sufficiently human though if not a little bit cancerous.
      And or disadvantageous mutations without the virus to turn them into advantageous.

    • @TarossBlackburn
      @TarossBlackburn 2 года назад +4

      That'll supercharge your winnebago!

    • @budgetbuyoutmisc.4916
      @budgetbuyoutmisc.4916 2 года назад +6

      @@RoanokeGaming Thank you Roanoke for adding to Roanoke tales

  • @UGNAvalon
    @UGNAvalon 2 года назад +958

    Normal immune systems: “EVERYBODY *PANIC!!”*
    Subject 0’s immune system: “Hehe, I’m in danger!”

    • @RoanokeGaming
      @RoanokeGaming  2 года назад +118

      Exactly!

    • @Asertix357
      @Asertix357 2 года назад +1

      AIDS is a bitch.

    • @Slavicplayer251
      @Slavicplayer251 2 года назад +34

      @@RoanokeGaming have you thought about covering st. Mary’s virus from v is for vendetta and wtf is going on with v’s biology

    • @GalenLeRaaz
      @GalenLeRaaz Год назад +10

      @@RoanokeGaming So, can this effect of Subject Zero be replicated by using immunosuppresants or wasting the immune system with chemotherapy?

    • @ghostwhencodghosts9114
      @ghostwhencodghosts9114 Год назад +2

      Delete r*ddit it’s 2023

  • @gracebirss90
    @gracebirss90 2 года назад +209

    As a biology/sustainability university student, I am LOVING the more science based conversations and topics. It really helps provide entertainment for me while allowing me to review material or learn new perspectives of certain theories. I’m a long term subscriber and I really am a fan of the work you put into your videos - so thank you!

  • @BartEmbregts
    @BartEmbregts 2 года назад +876

    Been waiting for this one. The game tells what the parasite does pretty well, but Roanoke just explains it in a much more entertaining way. Happy new year EVERYONE!!!

    • @logangrimnar3800
      @logangrimnar3800 2 года назад +19

      I don't like the game explanation, honestly, at least the part with the giant Kaiju and its Larvae. It seems totally out of place to include it at all and not address later.

    • @B_4035mn
      @B_4035mn 2 года назад +23

      @@logangrimnar3800 I think the kaiju is a setup for another game, in my opinion I believe the kaiju was something made to superseed planets with life, by an alien civilization.

    • @logangrimnar3800
      @logangrimnar3800 2 года назад +5

      @@B_4035mn It didn't feel like a setup, it wasn't presented as one. The characters showed no reaction to it and the existence of life in the solar system is never mentioned which is why the non reaction is so weird.

    • @beeb5872
      @beeb5872 2 года назад +5

      @@logangrimnar3800 I haven't heard any of the dialogue pertaining to the sea creature as I haven't played the game myself, but is it possible that humans are already aware of life below the ice? It would make more sense as to why nobody's particularly concerned about finding life in the solar system, at the very least.

    • @Dystopian_k1ng
      @Dystopian_k1ng Год назад

      ​@@B_4035mn Are you, by any chance, related to anyone named Ethan?

  • @Momo-tc7sc
    @Momo-tc7sc 2 года назад +601

    Dude, you just blew my mind with the question “Why do viruses have an innate desire to propagate?” I’ve honestly never considered that. How do scientists sleep at night with this kind of existential inquiry rattling around in their heads?

    • @logangrimnar3800
      @logangrimnar3800 2 года назад +159

      The answer is they do not, it's just that we only encounter the ones that do because because the ones that did not have no decendants. It's like the question about why the universe is so finely tuned for human intelligence, it's because if it wasn't, there'd be no one to notice.

    • @Momo-tc7sc
      @Momo-tc7sc 2 года назад +7

      @@logangrimnar3800 that’s groovy! 😄😄😄

    • @RandomInternetStranger
      @RandomInternetStranger 2 года назад +38

      @@logangrimnar3800 That's an excellent explanation, and I don't think I could have said it better myself. One thing we always forget in the process of evolution is the side that was unfit to continue surviving.

    • @Greenfeld13
      @Greenfeld13 2 года назад +30

      @@logangrimnar3800 You didn't really answer the question though I feel like.
      "Why do viruses have the innate desire to propogate?"
      A: "The answer is they do not, it's just that we only encounter the ones that do because because the ones that did not have no descendants"
      That doesn't answer why these viruses have that innate actuality within them. That explains why we only see ones that want to propagate, and not other sorts, but it doesn't answer why there is a "sort" that propagates at all. And by what mechanism these things necessarily have that quality "to propagate"

    • @wertuias1511
      @wertuias1511 2 года назад +12

      @@Greenfeld13 According to some studies, living systems increase the entropy of their environment faster than it would happen without them. Beacuse of that, on the long term, the existence of life is actually energetically favorable. As for the mechanism, you gotta look into RNA/DNA-polymerization and viral lifecycles.

  • @actualamateur149
    @actualamateur149 2 года назад +263

    Talking about modifying humans to quickly adapt reminds me of the movie Pandorum. Pretty similar concept. The people were meant to adapt to their new planet, but they adapted to the darkness and submerged ship instead, becoming monster-like.

    • @Broomer52
      @Broomer52 2 года назад +40

      I always love the concept of a virus mutating a body to its own benefit because on a certain level some do. My favorite instance of it was the Mercer Virus aka the Blacklight Virus. Named Mercer because of Patient Zero, Dr. Alex Mercer. The Virus absorbs and converts bio material, the end result is often something like a walking barely sentient tumor, geared towards violence. However occasionally it can encounter someone with the proper genetic makeup that a different reaction happens. The Virus consumes the body and gains the memories and knowledge of its victims essentially being a genetic copy of the victim to the point it could easily fool itself into believing it IS the victim. This self awareness in turn means it holds absolute control over its body and its viral capabilities, it consumes the bodies of others, gaining their memories and knowledge as well, is able to control its own spread consciously and is extremely hard to kill to the point of being virtually impossible as the nature of it means as long as a single virus cell survives and attaches to another living creature it will keep surviving. It was designed as a sort of Super Soldier bio weapon but because of its tendency to eat away at bodies and turn them into bio engineered monstrosities, it never made it far because having a super solider is pointless if the soldier is for all intents and purposes dead and runs the chance of being a Viral God.

    • @LunarEdge7
      @LunarEdge7 2 года назад +18

      @@Broomer52 Hell yeah I love Prototype..
      There has been a lot of power comparisons with Mercer and other superhuman and armored suit heroes that end with Mercer losing, not taking into account how Alex Mercer or the High Evolved would drag out fights and assimilate into seemingly harmless civilians.
      The Mercer Virus vs. supervillains or armored suit villains would end more interestingly or end up one-sided.

    • @Broomer52
      @Broomer52 2 года назад +19

      @@LunarEdge7 Mercer is functionally immortal. He practically took a nuke to the face and all he needed was a crow to get back on his feet. People seem to forget he’s not human, he’s not even a person. He’s a collection of Virus Strings puppeteering meat in the shape of a person. The only reason he got killed by Heller is because Heller ate the meat Mercer was inhabiting and is trapped in him. Theirs not much he’d lose to.

    • @itskashkashi
      @itskashkashi 2 года назад +1

      I think he did a video on that, I could be wrong but I feel like I watched it recently.

    • @actualamateur149
      @actualamateur149 2 года назад

      @@itskashkashi He did, it's one of his latest.

  • @inbredduck1487
    @inbredduck1487 2 года назад +591

    Your channel is one of the reasons im going to be a bio major. Nothing makes me happier than actually understanding the info in your videos. Love your content, man!

    • @RoanokeGaming
      @RoanokeGaming  2 года назад +129

      Ayyyy hell ya brother, we need more bio majors out here! Thanks for watching and good luck in the future endeavors!

    • @bloodysimile4893
      @bloodysimile4893 2 года назад +12

      @@RoanokeGaming I said we need more feet doctors if you ask me.

    • @heccers1998
      @heccers1998 2 года назад +9

      @@bloodysimile4893bio engineers can help doctors, so we just need more science people in total.

    • @dr.bright3081
      @dr.bright3081 2 года назад +1

      @@heccers1998lol pretty sure they were joking bro

    • @heccers1998
      @heccers1998 2 года назад +5

      @@dr.bright3081 im too neurodivergent for this 😭
      But i mean still, damn we need more scientist.

  • @karsonnukala5856
    @karsonnukala5856 2 года назад +720

    The more I understand biology the more unexplainable questions I have

    • @RoanokeGaming
      @RoanokeGaming  2 года назад +189

      It's a party out here

    • @natej3353
      @natej3353 2 года назад +41

      Reddit is a GREAT place to go for those questions. For example, the physics subreddit is full of PhD's and what not, completely willing to answer your questions.

    • @KumaoftheForest
      @KumaoftheForest 2 года назад +4

      It’s best not to think about it, you’ll drive yourself mad

    • @josephlemongello1255
      @josephlemongello1255 2 года назад

      @@natej3353 Reddit is full of misinformation and people pretending to have qualifications they don't have in real life.

    • @borgshadow13
      @borgshadow13 Год назад +4

      @@natej3353 same with the various biology subreddits :D sauce: doc candidate; waiting like 5 min between experiment steps just asks for casual browsing

  • @ToHonorKnowledge
    @ToHonorKnowledge 2 года назад +1841

    Had a toothache once, turned out it was an abscess in my face. Turned into sepsis, then a cytokine storm. After a day of intense pain and suffering I was left with type 1 diabetes and celiac disease from my immune system attacking my organs

  • @Roland1212
    @Roland1212 2 года назад +150

    I don't know if you noticed, but:
    before the final boss fight, there is an ancient tablet showing a guy with a spear fighting a monster.
    Puts all the "The Surviver" chatting the cult guys were doing in interesting light huh?
    (The p-something effect also shows they encountered this thing somewhere else before too)

  • @getschwifty5537
    @getschwifty5537 2 года назад +245

    Something I think could be cool for Roanoke to theorize about is actually the opposite of all these fictional super viruses: characters that have pretty much complete immunity to all disease.
    For instance, in the comics Hulk's immune system is so strong he had zero fear in handling a bleeding person who was known to have AIDS. And while I'm sure unraveling the biological implications of Hulk, Wolverine, Deadpool, etc's healing factors and immune systems is probably a whole can of worms, I guess my main curiosity after all this explanation of how viruses invade cells is how a cell could theoretically be super charged to be 100% impervious to ALL invaders or how an immune system could have such an iron grip over what material comes in and is allowed to persist.

    • @Sicdirewolf
      @Sicdirewolf 2 года назад +33

      The hulks biology is super interesting, I remember reading a comic panel where Tony stark figured out that the hulks body is constantly adapting but ONLY when bruce becomes the hulk

    • @jon7941
      @jon7941 2 года назад +11

      Also Spider Man. Healing factor BUT no particular viral protection. (For comparison.) Also Speedfreek huh? That was the Professor wasn't it?
      I gather he's gone up a few notches since then.

    • @infernaldaedra
      @infernaldaedra 2 года назад +11

      @@Sicdirewolf they've also done the bit where he's so radioactive that his body would kill any pathogens lol

    • @getschwifty5537
      @getschwifty5537 2 года назад +8

      @@jon7941 I assume you're referring to when Speedfreak gutted Hulk? Yeah while that still sucks for Hulk he's gone through a LOT worse in recent comics. Immortal Hulk by Ewing really ramped up the body horror and brutality that Hulk must recover from.

    • @jon7941
      @jon7941 2 года назад +3

      @@getschwifty5537 I was referring to him flat out stating he was immune to AIDS. Did he get gutted in that one?

  • @HunhowsShadowStalker
    @HunhowsShadowStalker 2 года назад +95

    An interesting point that a lack of exposure to disease and infections can weaken the immune system.
    I actually had a talk with my father about this, that the more parents try to "protect" their children from getting sick, the more they put them at risk in the long run. Things like using hand sanitizer whenever your kid goes outside rather than just washing their hands with soap could prevent them from developing a natural immunity to the stuff in the ground and air outside.

    • @anthrolitestudios
      @anthrolitestudios Год назад +1

      Oh. Oh no. I better use regular soap more

    • @etienne8110
      @etienne8110 Год назад +5

      That's why I feed rotten carcasses to my children.
      Why can't the child welfare protection agency understand that?

    • @anthrolitestudios
      @anthrolitestudios Год назад +2

      @@etienne8110 makes sense

    • @yiha9155
      @yiha9155 Год назад +10

      imo that's why everyone started getting the flu and common colds so quickly and so hard after the c0vid lockdowns. since we were diligent in sanitising and masking up to prevent the panny from getting worse, we also reduced our exposure and therefore resistance to seasonal illnesses that are usually no sweat to the average person. like, i got the flu this year and usually it sucks but it's not that bad, but because i haven't had it in SO long i ended up with fucking pneumonia and started coughing up blood for about two weeks with a sky-high temperature. it was horrendous. anyway i agree with you. dangerous or complex illnesses we don't fully understand yet - like the rona - should absolutely be avoided. but tummy bugs, colds, and sore throats? bring them on, we need them and kids DEFINITELY need them.

    • @RiTchieKII
      @RiTchieKII Год назад

      @@yiha9155the children yearn for sickness….

  • @Daddyduck88
    @Daddyduck88 2 года назад +45

    As a guy who puts boxes on shelves for a living, I find your explanations amazing and educating and it's something I really need to not turn into a caveman, never change please, love your content!

    • @ADUSN
      @ADUSN 4 месяца назад +3

      Don't ever disrespect or degrade yourself based on your job. Work has nothing to do with your intelligence or value as a person.

  • @logangrimnar3800
    @logangrimnar3800 2 года назад +91

    Hey Roanoke! Loving your coverage of parasites, which don't get enough attention in the current year, could you coverage on the *parasite stress theory* or the relationship between parasitic infections and allergies?

    • @goldkobold6496
      @goldkobold6496 2 года назад +2

      He’s actually brought up that theory a few times in various videos.
      I think one of the times he at least mentioned it was in the Black Friday video? It was definitely one of the movies with an alien in it.

  • @Nekavandre
    @Nekavandre 2 года назад +37

    The Minecraft music coupled with Callisto Protocol IRL Science and Biology applied to it is just cracking me up. Halo Bungie Era music is always a good choice as well (Not intending to start any arguments if you like the 343i Halo game music more power to you I just think they are distinctly different enough that you can't just say Halo music anymore). Don't ever change Roanoke. Love your work. Knew you'd cover this game and have a field day. Also you saying "Sicko Mode" now just absolutely sends me to orbit.

  • @dylandecker5883
    @dylandecker5883 2 года назад +45

    Hell yeah, I just finished this game and was really looking forward to seeing you cover it. It has such an interesting concept.

  • @Mexman75
    @Mexman75 2 года назад +55

    Still haven’t played this game yet but was excited to see what the science was behind the infection as the Necromorphs are still one of my favorite monsters in video games and was hoping this cousin like infection would be as equally interesting

    • @RoanokeGaming
      @RoanokeGaming  2 года назад +27

      It is interesting for sure but the game itself...needs a little bit of work haha

    • @Mexman75
      @Mexman75 2 года назад +2

      @@RoanokeGaming from everything I hear, your video included, it’s a bargain purchase later which I hate to do since I’m such a big fan of the genre but it is what it is.

    • @pitbullnamedcupcake8485
      @pitbullnamedcupcake8485 2 года назад +5

      @@Mexman75 I’ve bought and beaten it. Just wait for that bargain sale. Definitely not worth the 70 dollar price tag unfortunately

    • @isaaczavala5238
      @isaaczavala5238 2 года назад

      @@pitbullnamedcupcake8485 haven’t played it yet, but what were your issues with the game? Seen it’s had pretty low reviews..

    • @Goldenkitten1
      @Goldenkitten1 2 года назад +6

      @@isaaczavala5238 I'm honestly a fan of the game and would defend it given the chance, but to avoid a rant I'll just give you what you want and stick with the two complaints I see most often.
      1) Poor pacing; there's several parts where it's all action followed by a massive build-up, followed by talking, followed by build-up, followed by action, rinse and repeat.
      2) A lot are turned off by the prioritization of melee combat over gun combat which as you'd expect you do have a ton of ammo by the endgame but until about halfway through the game you'll be swinging through most encounters.
      There are some other more minor issues but those are the two I get seeing brought up constantly even now. There were also some frame dipping issues at release but they were pretty quick to patch that so if you see that as a major complaint at least know that isn't a problem we're really seeing anymore even though Steam reviews love to keep day one reviews up top for stupid reasons giving an inaccurate view of the current game.
      Like I said I'm genuinely into this game and am trying my damndest not to go off on a tangent in defense of it but those are the two biggies I see thrown at it a lot.

  • @russellbaughman
    @russellbaughman Год назад +9

    I really love the fact that he included that "the mitochondria is the power house of the cell"

  • @ianperry8557
    @ianperry8557 2 года назад +12

    God damn I love when a game showcases its disease well and then papa Roanoke allows me to whip out my old micro bio notebook and nerd out in unfathomably interesting such a great engaging video.

  • @thegrimcritic5494
    @thegrimcritic5494 2 года назад +4

    “Space is disease and danger wrapped in darkness and silence.” Hank “Bones” McCoy, “Star Trek (2009)”

  • @HunterSentinel
    @HunterSentinel 2 года назад +3

    16:15 dude you have literally shattered my entire perception of what life is.....
    Dear god, you, scishow and truefacts episode on dictyostelium have concretely rebuilt my understanding of reality entirely.... if only schools were as thoroughly entertaining and informative as you were our entire planet would be launched into a new age by now.

  • @danile948
    @danile948 2 года назад +1

    That Keeps joke was the funniest thing iv heard on RUclips in a while, your wit has done it again Roanoke

  • @lornastemen2472
    @lornastemen2472 2 года назад +59

    Hey Roanoke, are you excited for the opportunity to examine more necromorph feet?

  • @julespetrikov
    @julespetrikov 2 месяца назад +2

    Get this man a PhD, so that we can have even bulkier Roanoke, eating journals for breakfast.

  • @salacca2297
    @salacca2297 2 года назад +3

    1:15 Wholey Alive is my favorite un-released Flyleaf song.........

  • @enemyinbob
    @enemyinbob 2 года назад +7

    SO hyped for your breakdowns on the individual enemies!

  • @aarontrupiano9328
    @aarontrupiano9328 2 года назад +6

    c418 playing in the background makes this video even better

  • @starkillerob
    @starkillerob 2 года назад +15

    Ah, as a stern watcher of all your "how do" videos explaining various viruses, bacteria, plagues and other origins of movie, game and pop culture items, and as a gamer and microbiologist, I can say that I admire the amount of scientific evidence you incorporate in exploring the wide array of fictitious and also real-life oriented pathogens. I can attest to having done a couple of masters degrees in microbiology and public health, it'd serve you so so well in continuing your video series and your own career progression, great work as usual! Let me know whether you decide to pursue a M. of Science. Great video on the biophage from callisto protocol.

  • @MysticPoi
    @MysticPoi 2 года назад +4

    Therapist: Viral Roanoke doesn't exist, he can't hurt you
    Also Viral Roanoke:

  • @devinfox1236
    @devinfox1236 2 года назад +1

    Honnestly bro, i oove your personality and yourchannel, you are by far one of the funnest people i watch on youtube, your so interesting nad i always feel like ivelearned somthing cool by the end if your videos, keep it up! You deserve so many more viewers.

  • @Nappyheaded_sebby
    @Nappyheaded_sebby 2 года назад +7

    I just want an hour video of Roanoke talking about virus and debates about it lowkey

  • @Yavorh55
    @Yavorh55 2 года назад +9

    What's interesting/strange about all these "forced evolution"-type infections (Calisto, Dead Space, Killing floor, RE, etc) is how they turn the species to look more "monstorous"
    Suppose you look at things like convergent evolution. In that case, it points to the idea that there is an optimal form for a specific environment - it'd be interesting to see a "monster" force-evolved in a way that actually makes sense compared to its environment.
    Obviously this is done for gameplay spooky reasons and body horror, but still
    i.e. the slicy-choppy shoulder bits on a necromorph are sure good for slicy-choppy business but would they be energy efficient in the long run?

  • @thedoruk6324
    @thedoruk6324 2 года назад +8

    This was a very fast Upload! Its ironic that we could have potential extraterrestrial life almost every sattelite throughout our very own solar system and yet we think we are all alone out there! Happy early new year fav scientist!

  • @thedarkknight727
    @thedarkknight727 2 года назад +11

    It would seem that the ‘Blue Spider Lily’ the plant responsible for creating the monstrosity known Muzan Kibutsuji, that terrorized Japan back in the 1920s made it all the way to the year 2320.

  • @SalviAlmighty
    @SalviAlmighty 2 года назад +6

    Damn I love your videos, Ro!
    The way your explain such complex subjects is so easy to understand :))

  • @retroactivejealousy-worldl1805
    @retroactivejealousy-worldl1805 2 года назад +2

    Happy New Year and thanks so much for all your posts and your channel support in 2022 :-)

  • @hunterphille1280
    @hunterphille1280 2 года назад +29

    I know this is a odd reference, but have you seen the anime "Guver" where everything on earth was bioengineered by alien races to create weapons? I watched it as a kid and became a fan of the series which set into motion my fascination with biology. I know it's a real long stretch to your video, but topics like this remind me of that

    • @Naptosis
      @Naptosis 2 года назад +5

      'Guyver'? With the elbow shanks? So badass and ridiculous.

    • @Sicdirewolf
      @Sicdirewolf 2 года назад +3

      Guyver is badass there’s a old live action movie for it too

    • @john-Ro
      @john-Ro 2 года назад +1

      @@Sicdirewolf Guyver Mutronics and a sequel called Guyver dark hero.

    • @Sicdirewolf
      @Sicdirewolf 2 года назад +2

      @@john-Ro no way, seriously?! I’ve only seen the first one so it looks like I gotta check it out

    • @john-Ro
      @john-Ro 2 года назад +4

      @@Sicdirewolf yup Dark hero actually star's David Hayter (Solid Snake from MGS)
      The Guyver suit looks great and your gonna love the fights.

  • @thomasjoychild4962
    @thomasjoychild4962 2 года назад +24

    So Captain Ferris might have had some kind of immunodeficiency issue, too, given how he just turned into a bigger and nastier version of himself for most of the game and the warden called him a new subject zero. That last change into a giant inhuman thing seemed like it might have been a response to the ballistic and blunt/shock trauma Jacob was inflicting, rather than something that would have happened if Ferris wasn't beaten up then.

  • @ronaldhohnsbeen3231
    @ronaldhohnsbeen3231 2 года назад +7

    the fact that this video is more interesting than the actual game says something about papa Roanoake's content

    • @RoanokeGaming
      @RoanokeGaming  2 года назад +3

      ;) thanks for the compliment bro!

    • @ronaldhohnsbeen3231
      @ronaldhohnsbeen3231 2 года назад +3

      @@RoanokeGaming yeah man, you got me interested in biology a couple years ago and now I'm going to school to be an epidemiologist

  • @Screlz
    @Screlz 2 года назад +1

    Man Roanoke I swear I LOVE your videos. Me personally i always want to know more about creatures in movies, how they tick and how they possibly could be dealt with. The science aspect is so intriguing when it comes to allot of creatures, viruses etc and you make it as easy as possible to understand when it comes to the specific medias lore, even for someone like me who know very little when to comes to virology etc. My hat off to you sir. Im always looking to learn from you because you are a great teacher. Im so ready to learn more after you come back with that masters.

  • @diljornofish3600
    @diljornofish3600 11 месяцев назад +3

    Ah yes.....the mitochondria,the power house of the cell

  • @Anna464
    @Anna464 Год назад +2

    I really look forward to more Callisto Protocol videos!

  • @mister-zen8491
    @mister-zen8491 2 года назад +5

    Don't care what anyone says, I loved this game. Great job Roanoke!

  • @lucre113
    @lucre113 2 года назад +2

    Take a shot every time Roanoke says something about his virology degree

  • @sagebaca2013
    @sagebaca2013 2 года назад +40

    I absolutely loved everything about this game. Easily one of my favorite games I've ever played.

    • @r3darrow571
      @r3darrow571 2 года назад +3

      Did anyone see jacksepticeyes view on it kind of pissed me off not going to lie

    • @DisDatK9
      @DisDatK9 2 года назад +11

      I feel like we are alone with how much people are just relentlessly shitting on it. Like, it's not the greatest game of all time, but it's a pretty damn good one that scared me quite a bit. You'd think it was so bad by the reception that there was nothing even remotely positive, but once I finished it I enjoyed it overall and, though sometimes frustrating, the issues it had in combat didn't completely hinder the experience. (Ironic that many horror games get a pass for that because 'it's scary and supposed to be uncomfortable" yet for some reason doesn't apply here.)
      Incredible to me that the reception to Dead Space 3 was more positive than Callisto Protocol. Like what the actual fuck

    • @r3darrow571
      @r3darrow571 2 года назад +3

      @@DisDatK9 it's because everyone wanted it to be dead space and for some reason people had a crazy idea that at some point the devs said it will be the spiritual successor to dead space even jacksepticeye said these and people ran with that even tho these was never said once in the end its just morons that probably killed another great game because of stupid comments and lack of knowledge

    • @yondaimesin
      @yondaimesin 2 года назад +3

      @@DisDatK9 its mostly because of the advertising. it rode on the coattails of deadspace and didn't deliver a comparable product. Not the games fault for being its choice of genre but more on the advertising team.

    • @BeefMeisterSupreme
      @BeefMeisterSupreme 2 года назад +5

      @@yondaimesin The problem with that is that Glenn himself decided it was a good idea to double down on the spiritual successor marketing, rather than keeping his head down.
      People wonder why 76's happen when they always lap up Molyneux and good old chess club members

  • @WmdDracula
    @WmdDracula 2 года назад

    Watching ur channel grow brings me joy! When I first started watching your channel I was surprised there weren't more subscribers. Lol time is a game changer

  • @khanpudge5601
    @khanpudge5601 2 года назад +13

    Dead space : “it’s not an infection, it’s an alien!!!!”
    Callisto protocol : “it’s an infection “😗

    • @lukegeekwalker2689
      @lukegeekwalker2689 Год назад

      Callisto did it better

    • @mrmhj9925
      @mrmhj9925 Год назад

      But the infection is alien since Alien means, foreign in origin.
      It’s actually realistic in terms of the vastness of the cosmos. It’s probably teaming with unknown viruses and that’s the main horror of Callisto Protocol.
      It’s still the same horror with Dead Space with dealing with the unknown. Especially as the cosmos is teaming with ideas in horror.

    • @hellishthehellrellish5672
      @hellishthehellrellish5672 Год назад

      ​@@lukegeekwalker2689aint no way

  • @BoyWifeR0se
    @BoyWifeR0se 4 месяца назад

    Ive genuinely learned more from your videos than all my years from school, amazing videos man

  • @sebastianhasbun3846
    @sebastianhasbun3846 2 года назад +2

    Dude you have no idea how much your videos have influenced your viewers (including me) to discover a newfound passion for biology. I’m minoring in bio because of your vidoes 😂

  • @johnwilliam5540
    @johnwilliam5540 2 года назад

    Was waiting so long for you to post a video on the Callisto protocol

  • @williehughes1690
    @williehughes1690 2 года назад +2

    Fantastic video it's a shame the game itself wasn't as well designed as this virus. Also take a look into the creature's in the witcher franchise there's some really good stuff there.

  • @pajamapantsjack5874
    @pajamapantsjack5874 2 года назад

    I was waiting for Roan video on this, good stuff

  • @DrewishAF
    @DrewishAF 2 года назад +12

    The thing that always stumbles into my thoughts when considering the relative sizes of bacteria, viruses, the cosmos, atoms, subatomic particles, and humans is the fact that, somehow, human beings are actually almost exactly in the middle of the pack. It probably means nothing at all, but it just seems to dominate my thoughts for a while. It seems bizarre and unrealistic but that's only because we are really unable to comprehend a scale that vast. Even considering that the tiniest nearly-living things we can actually see are gigantic when compared to something like he size of the nucleus of an atom, it just feels like there's some type of significance to being directly in the middle of the scale. If you go from the scale of a Planck length all the way out to the size of the observable universe, it seems strange that we should be in the middle of those measurements.
    The other thing that always arises invariably from the "evolution" train of thought is the way most people attribute intent to the physical changes that occur between modified changes to genetic expression. It's not like an animal or species of flora can determine how to change itself to better fit the environment (aside from adjusting behavior, at least.) Consider flightless birds for a moment. There wasn't a day where some random bird decided to dedicate less energy to flying so it could run better. It's that there were some birds that were hatched/born less capable of flight but we're able to survive through different behaviors regardless of being less capable of flight. There were enough survivors with this slight difference/deficiency in flight ability that this attribute didn't make the animals die before being able to reproduce. They were able to find/use/exploit enough resources without flight that they secured a small niche in the food web. After several generations, there was no thinning of the flightless bird population so they just continued on living that way.
    Usually people will talk about epigenetics to the point where they basically assume that animals can consciously change their own physiology/phenotypic expression to better adjust to an environment. That is ALWAYS the train of thought that would-be "debunkers" try to use in their argument. They even go so far as to say "if humans came from monkeys then why are there still monkeys?" When I hear someone say that shit, I immediately know that they were just failed completely by the educational system(s). But, what they don't realize, is that they would actually have a valid argument if they were discussing the genetic component of virology. Regardless of that, the thing that doesn't make sense to me is the way people will consciously choose to debate/argue a point of contention (such as evolution by natural selection) from a position of ignorance or uneducated assertion. It's like they hear 3 sentences on a topic and there's no other available information. They also seem to believe, for some reason, that "science" is determined by some type of greater consensus regardless of future information possibly leading to a much different conclusion through trial, error, and iterations. That's also a huge reason why I love this channel. It's taken from a very reasonable angle where there are no solid conclusions and where additional information can actually modify each hypothesis such that a better conclusion can be reached without stating everything as inarguable fact.

    • @jinxedcat9843
      @jinxedcat9843 2 года назад

      Holy god my brains to slow to understand all tht😭

    • @ATF-
      @ATF- 2 года назад

      You have to come to the realization that humans fundamentally change with levels of intelligence. I have around a 140~IQ and the craziest concept for my trauma ridden brain to grasp as I was growing out of my adolescence, is just how stupid people truly are. I thought being smart pertained to how much you know, but it's so much more. Your ability to perceive, process, and extrapolate concepts. Your reflexes, your intuition, your situational awareness. Your ability to manage stress, and strategize, and formulate solutions. Everything comes down to how powerful your brain is. There are a few perks to being on the lower end of the bell curve, but not many. Most people are drones, bots as we call them. Theres no point in even trying. It's like you aren't even talking to a fellow human at times, it's like they're an NPC, and were programmed to live and think the way they do. Its terrifying once you really get into it all. It all serves a grand purpose in our survival as a species, you need the big brains to run everything, and the drones to do all the work. That's why for the majority of human history, leadership has been hereditary. This is still true, as the people who truly hold power in any society are the ones with money. They prepare their offspring in every way they can to fill their role, pass down generations of built on experience and knowledge, and eventually their wealth. The problem is there's a disproportionate amount of intellects that occupy drone positions in society, and to many drones in position of power. This is the basis of the impending revolution. Moral of story, people are stupid man.

  • @PSUjAYhAM
    @PSUjAYhAM 2 года назад

    Thank you have been waiting for this one. Happy New Year!

  • @drowzydullahan
    @drowzydullahan 2 года назад +8

    Funny enough, I've come to realize my immune system suffered during last two years. I lost my job (which was a whiles away from where I lived) back in 2020, right at the start of the year (A week after my birthday. Helluva start to the year) and because of the location I was in, was unable to really find work up until some friends snatched me up and moved me cross country (Where I now have a job, and am working on rebuilding my life) BUT! I've noticed I'm constantly getting sick now. My once Iron clad immune system crumbled to dust with basically 2 years of inactivity. At least, I'm assuming the essentially 2 year isolation period is the cause. But I ain't a scientist/doctor. I'm probably way off the bloody mark.

    • @sean7221
      @sean7221 2 года назад +3

      Could it coincided with receiving a certain Vaccine?

    • @Rad140Enjoyer
      @Rad140Enjoyer 2 года назад

      @@sean7221haha aye

    • @bryna7
      @bryna7 2 года назад

      @@sean7221 anti vax people watch this guy? Gross

    • @bryna7
      @bryna7 2 года назад +2

      @@sean7221 maybe if the trump administration had handled covid properly and told people about it in December and people had gotten the vaccine earlier, there wouldn't be so many people with long covid and weak immune systems.

    • @notsomebody4058
      @notsomebody4058 Год назад

      @@bryna7it’s not Trump’s fault that a lot of people didn’t trust a “vaccine” developed in under a year that also has like four if not more follow-up shots

  • @lukef.2320
    @lukef.2320 2 года назад +2

    Thank god! I needed smth to listen to at work !

  • @matchesburn
    @matchesburn 2 года назад +4

    Okay, we just need like an hour video of you going off on about virus, human DNA/genome, "Junk DNA" and all that, Roanoke. Just put the tinfoil hat on and just... hit record.

  • @Maeata
    @Maeata 2 года назад

    Was waiting for you to do this one!!

  • @GiRR007
    @GiRR007 2 года назад +3

    You cant just put minecraft sweden over the unending war of viruses and bacteria 😭😭😭😭

  • @the_furry_inside_your_walls639
    @the_furry_inside_your_walls639 2 года назад +4

    Interesting theory about Ferris and Patient Zero retaining their humanity due to immuno-compromisation, but I do think there's still a neurological/psychological effect on the host from the pathogen, especially once the mutations start kicking in, which I can only imagine causes a lot of pain and agony in the host. Granted, Ferris may have always been a psychopath from the way he spoke and talked, I don't think the stress from witnessing the outbreak and eventually being infected really helped his mental fortitude at all, and as he continued to lose more of his sanity, he became more violent. I assume that Subject Zero also went through a similar phase when he was infected, which may be why the other researchers may have felt the need to put him down.

    • @yan-rayiller-may8443
      @yan-rayiller-may8443 5 месяцев назад

      I'd also assume Dani Nakamura isn't going to have an easy time with her eventual "change" as well. It's a pretty bleak ending for everyone in the Callisto Protocol, everyone except the Warden of course. The rich and powerful will always win.

  • @OrionWendigo
    @OrionWendigo 5 месяцев назад +1

    All explained stuff aside: this game was really good and i enjoyed it thoroughly, never got to play Dead Space as a kid and Callisto Protocol happened to be on PS+ one time so i thought ‘why not?’

  • @theecchicero810
    @theecchicero810 2 года назад +175

    Today is my birthday UwU

  • @torqueblue
    @torqueblue 2 года назад

    The Peaceful Intro was nice, Then I heard Sweden And it Got a Lot better, Then I remembered this is a Biophage Video from The Callisto Protocol and Thought, " What an odd combo of a Things put together and yet, It works Just well."
    Awesome Video man.

  • @Nmohawk21
    @Nmohawk21 11 месяцев назад

    Your scientific accuracy is enthralling! It’s wonderful to hear the science behind all of your videos!

  • @carlosfrancisco1964
    @carlosfrancisco1964 Год назад

    Amazing video, man! Congrats 👏

  • @liamhamilton9086
    @liamhamilton9086 2 года назад

    Let’s be honest here, Roanokes jibber jabber explaining biology is much more understandable than an actual biology class. I took AP Bio once and for the life of me I could barely understand the teachers lectures let alone manage to scrape a high grade at the end of the class and a score of 3 on the exams.
    But Roanoke’s explantations just make sense and are understandable.

  • @dtay8913
    @dtay8913 2 года назад +2

    Been eagerly awaiting this one, thanks Roanoke, reminds me of the Dead space days.

  • @Pien-qo9kr
    @Pien-qo9kr 2 года назад +2

    Perfect timing as always, Roanoke
    Can't wait to listen to this one :]

  • @GaeLordPhockHer
    @GaeLordPhockHer 2 года назад

    Roanoke and that simeacing bloke. Prolly the two hardest working and best presented channels on RUclips

  • @RedneckResin
    @RedneckResin 2 года назад

    Roanoke two viral boogaloo sounds like the best channel ever totally can't wait for that

  • @AthamAldecua
    @AthamAldecua 2 года назад

    8:34 ROFLMAO, YOU TOTALLY GOT ME THERE 🤣🤣🤣🤣

  • @Afrafasti
    @Afrafasti Год назад +1

    11:00 according to this image, our sext evolutionary stage is pole dancing

  • @reecechapman7286
    @reecechapman7286 2 года назад

    YES iv been waiting for this video keep them coming please I love the calisto protocol and want to know everything about it and all the creatures and more

  • @SL4PSH0CK
    @SL4PSH0CK 2 года назад +1

    finally, i can sit and relax when it comes to Callisto Protocol

  • @Kezren1
    @Kezren1 Год назад

    Literally my favorite channel

  • @Deviated88
    @Deviated88 2 года назад +1

    Hell yeah! Looking forward to this, very much enjoyed Callisto Protocol so this will be sweet!

  • @jyoung4370
    @jyoung4370 2 года назад +1

    I cannot wait for Roanoke 2 conspiracy theory boogaloo. Shoot dude I would love to hear your thoughts on conspiracy theories in general. As in diving into different conspiracy theories. Keep up the good work

  • @kaoe145
    @kaoe145 2 года назад

    This video was so detailed. And I learned a lot. You definitely earned my sub.

  • @KitsiKatsue
    @KitsiKatsue 2 года назад

    I could listen to you talk about viruses for hours.

  • @ssbbutthead8862
    @ssbbutthead8862 2 года назад +1

    Ill definitely be watching for Roanoke 2 Viral Boogaloo💀💀

  • @johng29
    @johng29 2 года назад +1

    I've been waitinnnnn for this oneeee ❤️❤️❤️

  • @Arumell
    @Arumell 2 года назад

    Finally!! I’ve been waiting for this video 😊

  • @thatguy913
    @thatguy913 2 года назад +1

    I like to think of white blood cells as sentient noble warriors fighting off the invading zombie viruses to defend the homeland.....

  • @AFoxInFlames
    @AFoxInFlames 2 года назад

    I was waiting for you to make this! Yay!

    • @RoanokeGaming
      @RoanokeGaming  2 года назад +1

      Enjoy!

    • @AFoxInFlames
      @AFoxInFlames 2 года назад

      There are YouTubing virologists so you could go back and start a channel where u teach because you're so good at simplifying it. I was on my way to finishing in Microbiology and was going to go into Virology but I had a son and that kinda got dashed but I'm thinking of going back myself.

  • @st0nedpenguin
    @st0nedpenguin 2 года назад +1

    Roanoke is the only person to really figure out the true story here. The inmates were all super violent because they went bald.

  • @KIBOMoriStudios
    @KIBOMoriStudios 2 года назад +1

    New Thumbnail looks sick👌

  • @Cil-lan
    @Cil-lan 2 года назад +1

    I fricking need a video of you just playing spore while explaining how, why and when would your creature adapt and all.

  • @randallbesch2424
    @randallbesch2424 10 месяцев назад +1

    The Old Ones from "AT THE MOUNTAINS OF MADNESS" created viruses as helpful tools.

  • @haunterella
    @haunterella 2 года назад +1

    Boogaloo 😂gets me every time.

  • @1yanhao
    @1yanhao Год назад

    literally binge watching your videos rn

  • @shadowlord9607
    @shadowlord9607 2 года назад

    I admit despite how much of a mess Callisto Protocol is, the biophage and monsters are the best part of the game and roanoke explaining itself functionality and origins was fun to listen to.
    Maybe the next one could discuss the final boss and what it takes to retain sentience from being infected with the pathogen.

  • @syntax1235
    @syntax1235 Год назад

    I don't even care that this video was so rambling, I'd listen to a 3 hour video of Roanoke rambling on about microbiology.

  • @KatrinaLeFaye
    @KatrinaLeFaye 2 года назад

    Thank you for another intelligent video, such seem few and far between. Love your channel and take care.

  • @Somegoy
    @Somegoy 2 года назад +2

    Dude 7000 views in 40 minutes? Your killing it!

  • @danteredgrave5238
    @danteredgrave5238 2 года назад +2

    I just imagine that channel 2.0 will be live streams of his own viral creations. Explaining them on specimen and with the immortal words “let’s start with the feet” 😂

  • @Chumpkin1324
    @Chumpkin1324 2 года назад

    19:00 I knew I recognized that music as “under cover of night” from halo 1. Could never miss it.

  • @jeremybarrett3616
    @jeremybarrett3616 2 года назад

    Wooot!:D Happy to see you covering the biophage. Also the Callisto Protocol takes place on Callisto,the Europa Outbreak was caused by samples of the biophage being introduced into medical supplies being sent from Black Iron to Europa. Which caused the incident.
    (Only saying this because you said Black Iron was on Europa in the video) Anyways I hope you have a happy New Year Roanoke and may it be fantastic for you!:D

  • @harutothefriendlyodst7639
    @harutothefriendlyodst7639 2 года назад +2

    HECK YEAH I'VE BEEN WAITING FOR THIS

  • @davyheijlands1956
    @davyheijlands1956 2 года назад

    I noticed the little jab with at the "Keeps" commercial. Nice!

  • @Yurikid8807
    @Yurikid8807 2 года назад +1

    U have answered my call sir!!! I shall smash the like button like none other!!!