Stem cells have taken a long time to get their day, a lot of false starts, but finally they are. Now that AI has come into the picture in medicine, who knows what the coming decades will bring. And we NEED it. By 2050, the number of 65+ year-olds will have doubled, and the number of 85+ year-olds will have quadrupled. And that's in the best-case scenarios of countries like the USA with lots of immigrants. So what do we do? Get serious about this research right now.
Wow. I was a young nurse in the early 90s, attending an Apheresis conference in Houston, Texas. I can vividly recall s speaker introducing a modern plasma machine and mentioning the system to be the answer to finding the fountain of youth. Years later, I was working with a machine harvesting stem cells for cure in a research stage. I am now retired, and hearing these presentations indeed, pointing to yes, near the fountain of youth? Until this day, I only had seen the Trevi fountain 😂😊
In terms of the gentlemen asking about timing - it’s ignorant to laugh. It’s not funny. For example, in ARPA-H, one criteria for funding is the - so what? And is your research going to have a real impact on peoples’ lives in a reasonable period of time? And as far as “you didn’t know cancer survivors before, and now you do” goes - we used to use rotary phones and now we have cell phones. Point is - now we have tools like epigenetic clocks, AI / ML, models on protein folding, better imaging technology, not to mention knowledge of bioelectricity (which also ties into cell differentiation), epigenetic reprogramming, mitochondria, quantum biology, etc. We don’t need studies about the limitations of rotary phones. It’s 2024, not 2004 or 1984. Different times, different measuring stick. Same for biomedical R&D, tech transfer, distribution.
I am layman. I just wanted to bring into your notice there is something in UDST (Urine Devrived Stem Cells0 which helps longivity. Former Indian Prime Minister, Mr. Morarji Desai used to drink his own Urine every day and he became PM at a very late age and lived more than 100 years without any major health problem. His interview on this subject is available on BBC. Make sceientific studies if you can! There is a branch of study on this subject in ancient India, called Shivambu. Some literature is still available.
It's true...stem cells are present in all the organs and tissues of our body.. Extreme reduction of fats and sugars, carbs from our foods is the most dangerous propaganda... putting people directly into the possibility of suffering from cancers, Alzheimer's, heart disease, etc. Reducing stress is the best thing because this speeds up the formation and use of our own body's stem cells...and speed up repair of wear n tear .. regenerate and heal any of our ailing systems.
@36min. Why the stem cells are near the lyfatic system. Maybe it is because it is the drainage. (There is no garage, almost all lymfatic fluids are recycled). The drainage will tell the stem cell about the health of the tissue and thus if repair is needed.
what teleology? He presented on stem cells. How was his talk out of place in 'the scientific endeavor' ? Your comment should be clarified if it is to be considered.
I thought and felt he did a remarkable presentation with just the right balance, presenting the landscape, drilling down into a few details, inspiring viewers to broaden their view, and leading directly into the talk by his colleague. Examining all the factors, rational ( for that which is still being discovered), and various directions and co-factors is a plunge, first fired by inspiration.
If by teleology you mean the graphics used in the explanation, I think it simplified the complex scientific processes to something familiar that the lay person can grasp. I found it efficient, personally. I have always believed stress, physical emotional and mental has something to do with aging.
Well yeah but before we had No idea why yet what aging exactly is, we now have a relatively clear Definition as well as Most Major causes with Rough strategy plans which future developments will contribute to slowing or even Stopping and reversing aging
According to Matt Kaeberlein (rapamycin researcher), calorie restriction doesn't extend lifespan in all lab animals. He said that CR actually shortens lifespan in some lab animals, depending upon the individual genetics of the animal. And he suspects that the same thing would happen in humans. That's probably why Dr. Roy Walford (one of the first proponents of calorie restriction, back in the day) emphasized that his calorie-restriction protocol (CRON) was NOT recommended for people who are naturally lean, have low bodyfat, and can eat anything and as much as they want, without gaining weight.
Therefore - a human organism needs additional stem/slow cells and metabolic/communicative fast cells. To guarantee it, artificial tissues need to be layered. Third criteria is intercellurar communication, integration, etc.
I have never talked to the stem cells, cells, mitochondria, or white blood cells in my body, and I have never told them what to do, but they do their jobs on their own. Are they autonomous robots?
they are little elves minding their own business, if you talk nice to them and treat them well by having healthy diet and lifestyle they will work for you more happily
Thanks for this share ❤ I have some follow up questions out of curiosity: @ Dr. Signer to control the myeloid overproduction, which is more economical to alter the instructions of mRNA not to produce such 'apps' or to target elimination of excess 'apps'? Or does it mean we can try to stop it at 'code' level? And for the HSF1 is it feasible to control their count?🤔 @ Dr. Shiri how can the structure of the lymphatic system nesting with stem cells be maintained indefinitely, (maintain a young environment from onset)? And is there a possibility to 'rebuild' the old environment ? Or what's the feasibility of introducing an artificial young environment within the old environment? 👀
Even wear full body suit gloves boots helmet I still got TBI Thematic Brain Ingery, I don't remember what happened but I was told I was going too fast 😞 I had a Ducati 1299 PANIGALE S...
@@catcatcat8959 you should invest in a full body suit gloves boots Smart helmet, Smart helmet 360 head view with camera, you may be an expert motorcyclist it is the other driver on the road 🛣️ ... If you like motorcycles go to Closed loop track,if you crash you get immediate health Care,RIDE SAVE...
Talk one - great! But what ARE old super stem cells, and how do you make them? Is this published anywhere? That was the most important part. Is this in mice or people? Talk two - ok, so the supporting lymphatic / vasculature for the stem cells is more important than just the stem cells alone. So if there is no way to fix the lymphatic / vasculature - who cares? This talk is premature and irrelevant to people. Come back when you have a solution to fixing the lymphatic / vasculature for stem cells - or at least learned something that does not work so it’s not repeated. Otherwise this was a waste of time to watch, and a waste of funding to do unless the goal is to just sit and look at stem cells not performing well because of lymphatic vasculature. Pretty irritating actually when scientists think the point is their own self indulgence.
Check out "Reversal of Disease using a Whole-Food, Plant-Based Diet" here: ruclips.net/video/BsbQuXxP_O4/видео.html
Wonderfully detailed, thank you
Indeed, it’s an exciting time. Thank you for your hard work to improve health-span and thank you sharing your outcomes.
Stem cells have taken a long time to get their day, a lot of false starts, but finally they are. Now that AI has come into the picture in medicine, who knows what the coming decades will bring. And we NEED it.
By 2050, the number of 65+ year-olds will have doubled, and the number of 85+ year-olds will have quadrupled. And that's in the best-case scenarios of countries like the USA with lots of immigrants. So what do we do? Get serious about this research right now.
The first talk was great, a very impressionistic explanation of their research, certainly enough context to start reading up about it in more detail
Thank you for the information and your research. That’s a game change for a healthy living and lifestyle modifications
Tnx for Great jobb for all over world,from norway ❤
Wow. I was a young nurse in the early 90s, attending an Apheresis conference in Houston, Texas. I can vividly recall s speaker introducing a modern plasma machine and mentioning the system to be the answer to finding the fountain of youth. Years later, I was working with a machine harvesting stem cells for cure in a research stage. I am now retired, and hearing these presentations indeed, pointing to yes, near the fountain of youth? Until this day, I only had seen the Trevi fountain 😂😊
I found both talks fascinating. I would love more on how the lymphatic system works, in relation to cardiovascular health.
In terms of the gentlemen asking about timing - it’s ignorant to laugh. It’s not funny. For example, in ARPA-H, one criteria for funding is the - so what? And is your research going to have a real impact on peoples’ lives in a reasonable period of time? And as far as “you didn’t know cancer survivors before, and now you do” goes - we used to use rotary phones and now we have cell phones. Point is - now we have tools like epigenetic clocks, AI / ML, models on protein folding, better imaging technology, not to mention knowledge of bioelectricity (which also ties into cell differentiation), epigenetic reprogramming, mitochondria, quantum biology, etc. We don’t need studies about the limitations of rotary phones. It’s 2024, not 2004 or 1984. Different times, different measuring stick. Same for biomedical R&D, tech transfer, distribution.
Brilliant presentation!
Deep sleep and meditation boosts stem cells than any other food or any activity.
Interesting information
I am layman. I just wanted to bring into your notice there is something in UDST (Urine Devrived Stem Cells0 which helps longivity. Former Indian Prime Minister, Mr. Morarji Desai used to drink his own Urine every day and he became PM at a very late age and lived more than 100 years without any major health problem. His interview on this subject is available on BBC. Make sceientific studies if you can! There is a branch of study on this subject in ancient India, called Shivambu. Some literature is still available.
It's true...stem cells are present in all the organs and tissues of our body..
Extreme reduction of fats and sugars, carbs from our foods is the most dangerous propaganda... putting people directly into the possibility of suffering from cancers, Alzheimer's, heart disease, etc. Reducing stress is the best thing because this speeds up the formation and use of our own body's stem cells...and speed up repair of wear n tear .. regenerate and heal any of our ailing systems.
@@umaneelakantan9327 This is a new information.
This is really interesting but I would be astonished if the drug companies allow this to become a reality.
They want to own it, so they will.
We really want to be immortal
@36min. Why the stem cells are near the lyfatic system. Maybe it is because it is the drainage. (There is no garage, almost all lymfatic fluids are recycled). The drainage will tell the stem cell about the health of the tissue and thus if repair is needed.
Amazing explanation 🎇
Glad you think so!
Good TV
Any communication method between the stem cells? How to transfer genetic heritage?
The talk associated with DNA, by Dr. Signer, is very ladened with teleology, which is quite out of place in the scientific endeavor.
what teleology? He presented on stem cells. How was his talk out of place in 'the scientific endeavor' ? Your comment should be clarified if it is to be considered.
Scientific discussions include a lot a technological explanations so that the rational can be examined.
I thought and felt he did a remarkable presentation with just the right balance, presenting the landscape, drilling down into a few details, inspiring viewers to broaden their view, and leading directly into the talk by his colleague. Examining all the factors, rational ( for that which is still being discovered), and various directions and co-factors is a plunge, first fired by inspiration.
If by teleology you mean the graphics used in the explanation, I think it simplified the complex scientific processes to something familiar that the lay person can grasp. I found it efficient, personally. I have always believed stress, physical emotional and mental has something to do with aging.
Conclusion - As you get older things slow down and don't work as well as they did when you were younger..
Well yeah but before we had No idea why yet what aging exactly is, we now have a relatively clear Definition as well as Most Major causes with Rough strategy plans which future developments will contribute to slowing or even Stopping and reversing aging
In mouse studies daily calorie restriction shows exponential life span extension, but protein restriction not so much, only a bit
According to Matt Kaeberlein (rapamycin researcher), calorie restriction doesn't extend lifespan in all lab animals. He said that CR actually shortens lifespan in some lab animals, depending upon the individual genetics of the animal. And he suspects that the same thing would happen in humans. That's probably why Dr. Roy Walford (one of the first proponents of calorie restriction, back in the day) emphasized that his calorie-restriction protocol (CRON) was NOT recommended for people who are naturally lean, have low bodyfat, and can eat anything and as much as they want, without gaining weight.
Therefore - a human organism needs additional stem/slow cells and metabolic/communicative fast cells. To guarantee it, artificial tissues need to be layered. Third criteria is intercellurar communication, integration, etc.
So, you have to create smart tissues - stem cells, that formulate the "organ" with minimal intervention.
Last bastion would come from effective nanotechnological stem cell technology driven by AI. But when and where - we don't know.
Until we can't replace our skin for a younger skin... this idea will be an utopia, sadly.
And then the biological systems get more complex. The most complex system is the brain and nervous system. 2130s maybe?
"Health Span" via Stem Cell "Breakthrough" 2025++ ? Appreciating, "Longer, Healthier Life" Mission. Thanks.
I have never talked to the stem cells, cells, mitochondria, or white blood cells in my body, and I have never told them what to do, but they do their jobs on their own. Are they autonomous robots?
they are little elves minding their own business, if you talk nice to them and treat them well by having healthy diet and lifestyle they will work for you more happily
❤❤❤❤❤
Amazing insights and excellently presented ❤
NVIDIA ❤❤❤
Lifespan hopes and dreams
Thanks for this share ❤
I have some follow up questions out of curiosity:
@ Dr. Signer to control the myeloid overproduction, which is more economical to alter the instructions of mRNA not to produce such 'apps' or to target elimination of excess 'apps'? Or does it mean we can try to stop it at 'code' level?
And for the HSF1 is it feasible to control their count?🤔
@ Dr. Shiri how can the structure of the lymphatic system nesting with stem cells be maintained indefinitely, (maintain a young environment from onset)? And is there a possibility to 'rebuild' the old environment ? Or what's the feasibility of introducing an artificial young environment within the old environment? 👀
How strong are those bites? Looks like they can take a finger clean off by accident.
Timestamps would help your nice videos ❤
Done!
Suffered TBI Thematic Brain Ingery from a motorcycle 🏍️ in 2016 currently wheelchair bound currently,🕉️✌🏾
Eat Healthy food nutrients fruit vegetable seeds Nuts walnuts blueberries 🫐 strawberries 😊
Seeds Nuts walnuts almond 😊
Even wear full body suit gloves boots helmet I still got TBI Thematic Brain Ingery, I don't remember what happened but I was told I was going too fast 😞 I had a Ducati 1299 PANIGALE S...
@@RoshanPatel1441I keep seeing stuff like this now that I am close to getting a motorcycle lol
@@catcatcat8959 you should invest in a full body suit gloves boots Smart helmet, Smart helmet 360 head view with camera, you may be an expert motorcyclist it is the other driver on the road 🛣️ ... If you like motorcycles go to Closed loop track,if you crash you get immediate health Care,RIDE SAVE...
Um, if you are male aged 69. Should I get younger?
This idea is good but all people don't understand not at all people understand its very long long way to frame exaplaining to people
Hey, this isn't Seth Meyers
Bummer from the Comments this vid post sounds more lecture than prescription😮
Talk one - great! But what ARE old super stem cells, and how do you make them? Is this published anywhere? That was the most important part. Is this in mice or people?
Talk two - ok, so the supporting lymphatic / vasculature for the stem cells is more important than just the stem cells alone. So if there is no way to fix the lymphatic / vasculature - who cares? This talk is premature and irrelevant to people. Come back when you have a solution to fixing the lymphatic / vasculature for stem cells - or at least learned something that does not work so it’s not repeated. Otherwise this was a waste of time to watch, and a waste of funding to do unless the goal is to just sit and look at stem cells not performing well because of lymphatic vasculature. Pretty irritating actually when scientists think the point is their own self indulgence.
Just eat papaya everyday
Waw😊
Please don’t use model organisms, use ai?
Mouse
Umbilical cord juice😂
The benefits of slowing down. 🦥(12:07)