Timestamps BPC-157 @5:36 Thymosin B4 @17:07 GH Secretagogues @25:37 Pentosan Polysulfate Sodium (PPS) @39:53 Tying it all together @48:18 For those looking to try BPC-157, this is the current product I use personally and recommend for my patients, as it is the stable form of BPC-157: bit.ly/3kxMmYg
Hi dr Timmermans, i’m From Belgium and my doc here wants me to try the BPC-157 for chronic ibs but he doesnt know where to get good capsules in Europe!?
Hey drew, recovering from a accident recently with bad facial injuries, b4 the accident i was taking cjc1295. Do u think it would help with healing process quicker?
@@DrewTimmermansND what about the bpc 157 cream?? Is that for spot treatment to the area for muscle , joint, tendon etc...or just wound healing? Thanks for all your videos.
My father has had many back surgeries in his lifetime, and unfortunately, he is constantly in pain or discomfort. I sent him a few videos on BPC 157 and TB-500. He's 72 this year and overweight. He cant exercise because of his pain, so it's extra hard for him to lose weight. He hasn't said anything about yet. And he's old school and would probably be a hard sell. Man, I wish he would just give it a shot. There really aren't any harmful side effects either. I'll have to send him this video. Thanks Dr!
Drew, Thank you for doing these videos. My dad had a stroke. He's stuck in sub standard inpatient rehab facility. I'm using your videos to educate him and get him to try and heal faster and get home faster.
I have hole in my heart that produced a blood clot & essentially a stroke last week. Everything was fine but my upper left peripheral vision is screwed. Funny enough, I have bpc157 in my fridge that i ordered before the stroke. I'm familiar w/ the bpc157 study on stroke induced rats that showed remarkable brain recovery. I'm still a bit timid to take it because I don't want to make things worse or have some drug interaction as dr's put me on eliquis & a beta-blocker until I get my heart repaired. Would love more of my vision back though. Would love to know more.
@visionsno yes it can help those conditions. We use the InfiniWell brand as they use the arginate salt. We specifically use the Rapid Pro capsules. We have a 20% patient discount code on our website regenerativeperformance.com/supplements
This Dr. gets it. He is not afraid to step beyond establishment hash-lines. He is more for attacking the problem and addressing it than masking it through pharmaceutical meds and unnecessary surgeries. Question: I ordered the HEALTH BPC 157 capsules. Would I get more benefit by opening the capsule and doing it sublingually first before ingestion or not?
Appreciate those kind words. That approach wouldn't hurt, but not sure how much it would help as I dont know if the buccal absorption is good or not with the capsule formulation.
This video cleared up some misconceptions out there on several different peptides. I now know the difference between some of them, which is going to make my next order more targeted to my goals. Thank you very much for the detailed explanations of these peptides.
I find myself watching you nightly now. Just started BPC-157 for horrible shoulder pain an hour ago and might stack it with TB500. I truly enjoy your lectures, and if you were in my state ( I don't know, maybe you are) you would be my PCP. Thank you!
I’m interested in starting this myself. Are you mixing it together and injecting it? I’m curious if it matters where on your body you administer tb 500
@@skmg2888 Thanks for asking. I never ran the TB500 but I did run the 157 for a while. I also stopped benching and trained my chest with another means. I am about 80% better. I'll take that. It rarely bothers me now. I need to stay away form most side lateral movements and bench presses except on rare occasion, and I'm golden. I also used a lot of red light therapy which I still use. I think that played a big part as well.
@@nuclearkamikaze Yes, I reconstituted and injected it using bacteriostatic water. I thought about adding it in as an oral as well, seeing as how it is one peptide that you can, but I found that not to be cost effective. I also chose the sub q route for injection site in the effected deltoid. Even though it is considered a "smart peptide" and is said to find it's way to the area that needs increased blood flow for healing, I went as close as possible. If I had a knee issue, I would have gone close to the knee. It just makes sense to me.
Thank you for this video I feel like this was the best one I’ve watched and I’ve watched a lot. I’m starting a daily oral dose of BPC 157 in a few days to help with some nagging golfers elbow and a few other injuries. I think I’m gonna take it for one month early and see how I feel then I might even try a month of injecting it close to the golfers elbow.That was recommended by a doctor to start orally he thinks I’ll see results within two weeks I’m pretty excited nagging injuries have slowed me down a lot in the last few years I’m excited to heal them up.
Thanks for making this public. My life is trial and error with health issues. When I was a kid I took shots of HGH due to pituitary issues. Around age 13 I had extreme anxiety and depression and insomnia. Basically had that ever since (nearly 40 now) and have tried various antidepressants, TMS, Ketamine..everything. Then I stumbled on Selank and it worked better than anything I've tried. Not sure why the doctors didn't go for more pituitary focused methods but what one country approves of another sees as useless I guess. Only thing I'm trying to figure out is the physicality with Selank. Can't find much information on it. SSRIs definitely slowed me down for certain workouts (martial arts for instance) and I can't tell if Selank is doing something similar or if it's actually helping coordination/power output. I also have hypermobile joints (last SSRI helped me tear my right shoulder) so might look into the BPC for that. Doing experiments
I'm terribly sorry to hear that. It may be worth researching and exploring cervical instability especially if you are hypermobile, as this can cause a whole host of central neurological issues. No idea if that's your case, but might be worth exploring.
@@DrewTimmermansND she down in Florida, has a large wellness clinic….. she created the practice terms Peptologist, Peptology…… Even offers a “certification”and ways to incorporate and market peptides into ones practice.
It's great to see that more doctors are using peptides more and getting the message out that they can help. I think it's a little much for us to start adding these terms to them, especially because the word peptide does not just apply to the medical peptides we use. A peptide is just a sequence of amino acids, and is ubiquitous throughout biology and physiology. I've been studying peptides for 9 years now, back when you had to find obscure forums to even learn about them because no doctors were even using them that long ago.
I have arthritis just above the sinus tarsi area in my left ankle. For about 7 years, I've been dealing with burning, prickling, stabbing inflammation pain that would become more pronounced with certain weather patterns. So I had 2 Prolotherapy injections and then 1 PRP injection. It helped, but I was still having many bad days. So I opted to try one more aggressive round including the following protocol... (1) another PRP injection with AOD9604 +HA peptide (2.) The following 3 weeks, one injection per week of AOD9604 + HA peptide (3.) .15ml of BPC-157/TB-500 blend injected daily into my ankle for 3-4 weeks. We'll see what happens...
Hi Doc, Excellent lecture! I know, and I studied quite a lot about peptides, hormone optimization, PEDs, and overall fitness pharmacology. I've also been experimenting with most of those myself for longevity and anti-aging purposes. Furthermore, I'm self-taught. Could you please recommend me a career path that I could undertake with all this knowledge at my disposal? I truly know a lot, and most endocrinologists I confront myself with are always impressed however I'm not interested in a degree as MD, so I lately considered a B.Sc. (Hons) in Health Sciences. However, I'm not quite sure if it does even exist a Master's Degree in Peptides or in Hormone Optimization that I could undertake afterward with such a degree. Moreover, I study these for fun and because I'm actually very good at it, but this is not my main work field. I do also know quite a lot about nutrition, and training, but that's not a career I'd like to pursue. Please, any advice would be very much appreciated from an expert in this sector.
great question man. Currently, there aren't any formal university/college degrees in peptides. Have you considered looking into becoming a naturopathic doctor (the type of doctor I am)?
@I know a…. You might consider getting to know the studies about the eight essential glyconutrients that make our stem cells. There is no endo system without them, and you won’t get the true story from med school. They run the show from the bottom up pretty much. Without these eight saccharides at the very minimum, there is no making, repairing, regenerating or messaging of other parts of our biology physically. So there are many devotees going into the study of glyconutrition. In conventional medicine, immunologists are informed about them, but for lucrative business’s sake, they are taught to keep it mum that you get get your own stem cell treatments from your own kitchen. Beware of the wiles of the conventional thinking ones-the ones who will ONLY think the way they were orogrammed in med school where 70% of their med school curriculum is actually written by drug company employees who aren’t even doctors (that is actually a true fact). I’d save that for if you ever need a busted leg set. For “all things immunity and degenerative”, look to glyconutrition. Only ONE food group can make stem cells. Carbohydrates. Why do you think there is so much propaganda against them by the conventional medicine set? If we are missing even one essential glyconutrient, we are in trouble, and a lot of us are in trouble. When we add it back into the diet, we now have all eight glycos in order to make the stem cells we need and also in order for cell to cell communication that would be flawed if even one missing. MIT calls glyconutrients “the missing food group”. There are books about this, like “Sugars that Heal”, and “Glyconutrients”, and “Miracle Sugars”. I have used these for many years, but don’t expect to get answers from your conventional doctors about them-it was mostly kept from them during med school, other wise, they wouldn’t serve the drug companies. Take care of yourself so you can take care of others. There are powers that be who would attempt to stop you from learning about this. God bless you in your journey. (Copy’d b4 pst)
@@DrewTimmermansND I saw you wnet to western. I'm from Ottawa and moved to Maryland in 99'. Cheers. I've been looking into Peptides SARMS as of late. Thank you for sharing this valuable information.
At 33:06, I guess there's a mistake. CJC-1295 isn't sermorelin. - The origin GHRH contains 44 amino acid - Sermorelin contains the unmodified first 29 amino acids of the origin GHRH, also called GRF 1-29 (half-life shorter than 10 min) - Mod GRF 1-29 is a modified sermorelin, where 4 amino acids were replaced, also called CJC w/o DAC (half-life arround 30 min) - CJC-1295 is also a modified sermorelin, but with an added "DAC" instead of replacing amino acids, also called CJC w/ DAC (half-life about a week) Correct me if i'm wrong.
Wow thanks Doc. This is one of the best lectures I’ve seen on these peptides! For some reason injecting CJC + ipamorelin before bed gives me issues as well. It’s like a slightly elevated heart rate with a heavy pounding sensation. Nothing crazy but enough to keep me up, which is strange because supposedly these peptides don’t raise cortisol. It doesn’t seem to happen every time though. If I take it during the day it’s not noticeable whatsoever. Also, any chance you’ve delved into GHK-Cu in another video?
Ipamorelin can like other HGH substances, can decrease insulin sensitivity and have your blood sugar raise. In your youth you were likely more active and your body acting youthful and you not utilizing the energy likely has a surplus at night.. probably damaging for your pancreas. Just a guess... Based on information from forums on the subject.
Dr T, will you please to a video on tesamorelin and the benefits of adding it as the ghrh to ipamorelin? Thank you and love your videos. I have learned a ton
Thank you very much for the great information. I’d love to interview you on our podcast about martial arts and mental health. There’s a ton of people in my audience who want to learn more about this topic
Thank you for the offer. Unfortunately due to current FDA restrictions on peptides and therefore it's near impossible to get these peptides from a compounding pharmacy, I'm not doing podcasts on peptides at this time. Additionally, mental health is not my area of focus. Thank you
Hello, this was a very helpful video and very thorough regarding peptides. I myself had an accident in gymnastics and I tore all of my ligaments in my left knee. I also tore my biceps muscle and have a small indent in my bone..so yea it was a pretty bad injury and being an athlete I searched for all the Best practices and medicines regarding post-op regeneration and rehabilitation and then I stumbeled on peptides. I am already interested into taking BPC and I will Use all the recommendation you have listed, But my only question is when to take it? Thank you for the great content and spreading the awareness of the great use of peptides
I'm terribly sorry to hear that. If peptides don't resolve your issues 100%, it may be worth looking into a consultation for regenerative injections. We dose oral BPC-157 once per day for most people, taken with food
Thank you very much for the answer. I am on my own with this one because in my country it not common to cooperate with doctors with regeneration methods. So thank you for this kind of content for those who don't have other means
Wow, this is great! Thanks for sharing! I am currently 7 weeks out from ACDF surgery and was recently prescribed TB4 to aid in my recovery process. I just started today so I can't say definitively that it has helped but my hope is that it will help primarily with the weakness I still have from the nerve damage. Do you think this will help speed up the process of nerve regeneration? Thanks!
Just saw a video from 3 yrs ago that SKorea found a peptide to help RA. That brought me to your video. Do you do any work with RA patients (of course they are doing it overseas!!). My 81yo Dad just diagnosed with RA though I’m sure he’s had it for years (5 joint replacements in 5 yrs). Do you think allopathic medicine will ‘prescribe’ peptides for pain?
Thanks for watching. Anti-aging peptides are not my primary area of specialty so I don't speak about them. Other youtube accounts might be better for you
Hi Drew. I’ve been doing Prolotherapy since 1995, PRP, since 2007, and bone marrow & adipose stem cell treatments since 2008. But I’m brand new to peptides. This is an excellent lecture! Very clear and informative. However, this lecture was 3 years ago. Has your treatment algorithm changed since then regarding dosing / usage?
Dr Timmermans would you be able to help a 10 year old neutered male 50 aussi shepherd (dog) with a pretty advanced trigon bladder cancer. Thanks and bless you
Would you consider using CANNABIS OIL as it has phenomenal effects on humans with even extremely advanced stage 4 Cancer. Not HEMP derived CBD oil, but Cannabis derived oil in the treatment
So I have seen many recommendations for Tailor Made Health by reputable people, like you, but I found a complaint filed against them by the FDA in 2020 for, among other things, unsanitary conditions. I am just wondering if you have some insight that leads you to this recommendation because I don't know who to trust for purchasing BPC-157.
I degloved my ring finger about a week ago in the gym , crushed it in between two dumbbells, i started BPC 157 and TB 500 two days ago and i hope to god it works and speeds up the recovery , nail was ripped off and fingertip broken too , end was degloved so i am hoping for new cellular growth for my fingertip please help 😢
Hey Drew, Appreciate the content. Have been researching various peptides over the past 8 months with an interest in healing and recovery. I enjoy reading the studies and breaking down the data. As this is still very underground in comparison to conventional or western medicine there are many nuances. I believe hormonal and or naturopathic clinics will certainly be the go to in terms of guidance and transparency as they have clinical tools and knowledge as well as access to compounding pharmacies. In the description you've provided a link to DNA health and I was wondering if you knew where they sourced their peptides from, maybe a specific compounding pharmacy? Best, Drew
Hey Drew, DNA Health is a supplement company therefore they don't purchase raw materials from compounding pharmacies. They own the patent for BPC-157 arginate salt. I don't know who actually produces that.
Amazing video. Would any of these be helpful for a person that deals with multiple issues related to old TBI injuries? Migraine, nausea, chronic fatigue, etc? Thanks again for the video. 🙏🏻 Watched this twice now, such valuable info.
Heck yes!!! More vids like this!! 👏👏 Question: with the GHRP & GHRH, do you need to take a break from these compounds after a few months? Or can you use it continuously? If so, does the cycle vary by the amount used?
Glad to know you appreciated the video! It depends on how frequently you're doing the secretagogues. If you're just pinning once per day, if you take one day off per week most people can continue for 6-12 months without any evidence of negative effects. We don't necessarily recommend that though, as we believe that humans evolved to have periods of fasting and feasting. So if someone does GH or GHS for several months, we intentionally want to scale back all anabolic substances and approaches for a few months as well.
They aren't 'pointless', but they don't provide an advantage over oral for most patients. Some patients still respond better to injectable, just not a large majority. SubQ injections over the area of pain is pointless
Hey Doc! Rock climber here. I'm currently supplementing BPC-157 and Thymosin Beta-4 to treat a labrum tear. I have them both in a nasal spray application, I was wondering, what dosage should I be taking of each? I've done tons of searching but with no luck.
I'm two bottles in with bpc 157 for my shoulder IAM 57 work full-time in a metal shop work out 5 days a week my right shoulder either has arthritis or a rotator cuff injury they did x-rays and that's what they determine getting cortisone shots which helped for two months and I'm tired of it and I got enough bpc-157 6 to 8 wkks IAM happy with it so far 🤞💪😉
We usually do 500mcg oral. If the patient is getting better at 2 months then we continue until they are no longer getting better (also called a plateau). Then we reassess.
Hey Drew! Loved this in depth lecture. Since the BPC 157 on infiniwell is currently sold out, would you recommend the rapid or delayed release to help aid elbow tendinitis & a wrist sprain? What pros/cons do each one have? Thanks
Hi Doctor thanks for the info. Do you think that BPC 157 would be helpful after a full hip replacement (4 weeks ago), or at least worth discussing with my surgeon? I am a 28 year old male and generally healthy, replacement was done due to avascular necrosis . We were not able to identify the cause of the avascular necrosis. I have also been experiencing pain in my right shoulder for years, same side as hip. If I do want to talk to my doctor should I consult my GP or surgeon? Thank you so much in advance for any help in this regard.
So much great information. Thank you for helping the community 🤙 When you say that BPC is produced by our bodies naturally, does the amount of our natural BPC decrease as we age like hgh does and that's why we should supplement it? Or does it remain at more consistent levels throughout our lives?
My pleasure, thank you for those kind words. We unfortunately don't really know anything about the natural production over life as those studies haven't been done.
Hey! The 250-500mcg/d dose for BPC 157(vitalbpc157) is based on limited human data and rodent studies. Higher doses or longer use could have unknown risks since it's not well-researched in humans yet. Better to stay cautious and wait for more research to ensure safety.
@@troy3423well if you can’t afford and need healing you may not be able to wait. But generally they block research if it will help people. The places that fund the research won’t fund it if it isn’t a money maker and I think peptides you can’t really patent. There are risks with everything but verbally many have taken this without issue so at some level that is a test even if there are less controls in place. But if you’re waiting for the major groups that do research to research a thing they can’t patent and profit off of I doubt that will happen anytime soon. There are risks with anything you take. So you research and try to assess that and decide if the risks are acceptable. But for those in pain if they see many benefit form a thing and have no assurance research will be done this century it’s maybe not enough to tell them to just wait and hope as their body degenerates.
Hi Doc, how effective is BPC-157 with recovery in peripheral nerve damage to the legs/feet? I Believe I have the Acute motor axonal neuropathy (AMAN) variant of Guillain Barré Syndrome and was wondering if this peptide would speed up my recovery!?
What would be your recommended dosage and frequency of BPC-157 & TB-500 Blend (10mg) injections for a college football athlete with a torn labrum (shoulder)?
This video has generalized dosing. For individualized dosing approaches, you would need to become a patient so we can put together a full protocol that is specific to you and your case.
Hello Dr. Timmermans, I contacted you on here although I don't see it here to ask of you knew someone in Vancouver to give me shots of Thymosin B4 and you replied nobody. So I was wondering how much I need for torn cartilage and for how long. After listening it sounds like I would do the 750mcg,(.25ml) daily for 20 days. Can I get a nurse to inject this? And does it go into the fatty soft tissue? between the bone? How much would I need for 20 days?
Sorry I don't know anyone in that area that can give you shots. On average we use 750mcg for 20 days in a cycle. Most patients get the product and then inject it at home into the subQ tissue
@@DrewTimmermansND Yes, thank you did get the original message of nobody in my area. Okay you just confirmed what I wanted to double check. Glad you have been on here and available for consulting.
Dr. Timmerman, I have a thumb that got bent back and doesn't want to fully heal, and rotator cuff that prevents me from pitching baseballs to my sons and I also had a recent brush with frostnip that caused the circulation in my feet and toes to decrease. Do you think BPC-157 might help me with some of these problems? Thank you so much for your wonderful work!! :)
We find BPC-157 helps about 70% of people when you lump all ortho conditions together. So I'd give it 70% chance. Make sure you use a good form though. We use the BPC-157 capsules from InfiniWell as they use the arginate salt. To help out, we have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20). Once on that website, click the InfiniWell link, and then choose the product labeled 'BPC-157'. When you hover over the product, you will see it says 'Original Formula' above the ingredient box). This is the version that does not have SNAC, which we find works better.
Hello Doc, thanks for the great lecture I’m just wondering when you said BPC in clinical practice worked better in combination with a stimulus. Would ART (active release technique) be a good stimulus? Or isolated exercises in the gym work? Can you also explain what ‘guasha’ is? the first stimulus you mentioned. Thanks again in advance. Regards, Jack
Great lecture, I learned a lot… But you kind of lost me at 39 minutes 44 seconds when you mentioned the “anabolic window” 😳 do you believe this exists?
No my thinking has evolved since then. I still believe for some people it may be important to get protein/calories in asap after exercise because it allows for more calories or protein to be consumed within a 24 hour window though.
Outstanding video, thank you. One question about the HGH quantity released by using GHRH+GHRP. Economically and quantity wise speaking, is it more convenient use straight HGH or is it better use GHRH+GHRP? To how many UI of HGH would be equivalent use 200mcg GHRH + 200 mcg GHRP? I mean, what if I just directly use HGH injections of 2 UI daily?
Hi Dr Timmermans, I have just had a chat to Infiniwell as I saw you posted their link in another comment. Sadly they don’t ship to Aus. I was wondering if you knew a reliable company that ships to Australia for BPC-157 capsules?
The only thing i would like to add due to personal experience i took bpc157 from a good source in capsules to heal ligaments and it did nothing, it needs to be injected as close as possible to the injury. It does make a world of difference.
Some people do not respond to oral and they respond to injectable, and vice versa. I'm glad you found what worked for you! But to clarify as we have worked with over 500 people with BPC-157 at this point, and your statement is not true for most people. Be careful telling people that the only way something will work is what worked for you, because that's not true for everyone. Majority of people see outstanding results with oral BPC-157 and they do not need to inject it. Some people do need to, but most people will see significant benefits from oral.
@@DrewTimmermansND the vote is still out for ligament laxity, i got prolo and PRP but now my sport doc is on a break trying to fix what is left with the peptides. To be honest even sub Q tb500 and bpc not sure its going to work for ligament laxity, i do feel better my hips are stronger but i still get some groin pain. I will be on about 6 months, i am 1 month in. Also using cjc and ipa and added 1 month cycle of IGF1 LR3
"I'll tell you this: everybody has something they'll respond to better. Some people do respond better to oral... I trust the patient's intution. If the patient comes and says, 'You know what, I think I'm going to have a better response with oral'... then I say, 'Alright, we're doing oral.' If they don't... I tell them to do oral, because then you don't have to worry about syringes and needles and it's just a nice easy... oral." -- Drew Timmermans ND
@@DrewTimmermansND There's much wisdom in that quote. I suggest you make a picture with that quote written in a cool font (I suggest the Led Zeppelin font) next to a photo of you in a majestic pose and that you post it often on social media. As your pro bono attorney I guarantee you this will be good for your career. P.S. It'll also be a good career move for you to pin these comments to the top.
Sometimes, yes of course. I've still seen enough times where patients were indifferent and one form did better than the other, so i don't believe it's all the time. I'm happy if they get a bigger effect because part of it is placebo. They get more healing and I am okay with that 😉
So in case I missed it. For BCP-157, would injuries be a stimulus? I suffer from hEDS and I am in amazing shape through years of hard work but soft tissues always hurt regardless of any modalities used i.e physical therapy.
Hi Doc, I have intermittent hydrathrosis (my knees swell one week out of 2 without any damage on MRI) I have a CRP about 12. What would you recommend me to try ? Thank you for sharing your knowledge with us, it s so interesting
I'm sorry but I can't provide specific recommendations for you to try unless you become a patient of mine. If you'd like to look into this further, you can find more information here regenerativeperformance.com/contact. Our goal is to get to the root cause of why you are having these symptoms so that we can provide personalized treatment recommendations for you, which address the root cause.
Hi Doc, great info and lecture! I just ordere BCP 157, had motorcycle accident and broke both of my hand wrists, tendons and ligaments injured as well. I want to go back to training, please can you tell me if I need to administer injections on both injury spots, should i split the daily dose in that case or not? Thank you in advance!
Hey man, I cant give you advice on what to stack that with. If you're going to inject the BPC-157, you only have to do it in one spot, and the abdomen works perfect
@@DrewTimmermansND Thank you so much for fast reply! Just one more question if you find time - Since I've read all around that it is better to administer dose 1-2 cm from injured spot, should I administer it like that, or to stomach like HCG since I have couple of injuries! Thank you!!
Injecting close to the site of injury is bro science and isn't actually true. Some may get placebo effect from that, but it goes systemic almost immediately after injection, so just into your belly is great
Great video, thanks for the amazing content. Does Mod GRF 1-29 combined with Ipamorelin lead to typical side effects from elevated GH levels? Let´s say for the dosing of Super Saiyan Effects. I can´t find anything about that issue and am wondering why they warn about so much side effects for HGH injection (in short: growth of everything) but for the peptide use this does not occur? Thanks a lot!
To the camera man, for future use, Just put up the slides of the slides We don't need to see the presenter , it is just distracting. . .. And when you draw back the slide fades to very light, and see it fasteniugh if I haven't memorized the slide in 20 seconds, LOL THANK YOU . . .
Doc! Thanks for the video. I’ve gone through two ACL‘s and torn meniscus. Both knees are just not good. Been in pain for 10 years I’ve done everything possible so far. PRP, physiotherapy, massage, acupuncture and this last month was on BPC 157 but no effect what can you recommend doc, can’t handle it no more
I'm terribly sorry to do that. Your case is unfortunately too advanced for some simple recommendations on youtube. These cases we would need to work one on one so we can get to the root cause. If you'd like to see if we're a good fit to work together, please fill out an application here - coda.io/form/Dr-Timmermans-Initial-Screening-Application_dLRPTx2mJ1T
Do you believe BPC-157 should be accompanied by anything, like TB-500 or TB4 Fragment? About the capsule form of combo BPC-157 & Thymosin B4 Fragment; is the fragment part (Ac-SDKP) of no use because it's capsule form? Do you have any opinion on infiniWell as a source?
yes they can. We have successfully treated and resolved neuromas with PRP nerve hydrodissection and adipose stem cells. Would you like to explore working with us? If so, please reach out to my clinic! regenerativeperformance.com
Pretty sure there are numerous publications where they are trying to administer GHRH over prolonged periods (eg with an infusion pump), prior to the discovery of CJC-1295. In studies on CJC-1295 the authors often note that boosting the overall baseline is healthier and more physiologically relevant than giving these supraphysiological pulses with a bolus administration, and that bolus administration is the cause of the majority of GH related side effects. Do you have a scientific opinion on this? What you said about the benefit of bolus dosing around min 33-34 sounds very much like bro science and not what the literature says. If you could share some references explicitly supporting short-acting bolus GHS dosing to achieve some type of benefit that is superior to longer term release, I would genuinely love to see them
Hey Dr Timmermans, what do you say to those "studies" that say that there is a risk of cancer associated with peptides to the angiogenesis? Id love to try tb4 to help a small ligament tear i have in my shoulder. And for ligaments and tendonitis would you recommand tb4 or bcp 157? Thanks!
Pretty niche information. Thank you!! I have slip disc diagnosed. Majority pain is in the lower back right side and slightly into hip. I test positive in straight leg raise test for the right leg. I'm usually fine even while Deadlifting and squatting. It gets severely aggravated after playing soccer where I have to change directions quickly and sprint fast too. The pain the next morning is quite debilitating in the low back and bending at all. I have started bpc157 recently as no doctor deals with such methodologies in India. Does tb4 fit my use case more than bpc? Or any other things you would suggest to your patients?
Drew, you mentioned "epicondylitis" and "epicondylosis". These are outdated words and have been outdated for over 15 years now. The correct terminology for both is "tendinopathy".
Respectfully, I'd have to disagree with you. First, academic journals publish a great deal of articles using these terms, even in 2020. If they were truly outdated by 15 years this should be reflected in the research now. Second, tendinopathy is a generalized term for pathology of a tendon. I personally dont agree with lumping two different pathologies (osis and itis) into one collective term, because pathology is different and treatment approaches should be different.
Some people can have some histamine reactions from BPC-157 but we really only need to be cautious in people diagnosed with MCAS. BPC-157 is still better then tb4 for gut issues. If you're gonna do BPC-157 make sure you use a good quality arginate salt. We use the InfiniWell brand as they use the arginate salt. We specifically use the Original Formula capsules without the SNAC. We have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20).
Thank you doctor for the information you gave. I had an accident and still trying to recover from multiple conditions. What is the difference between TB500 and BPC 157. there is a product which is combination of two. which one we should choose.
I'm not sure which one you should choose, as I'm not your physician sorry. TB500 comes from TB4, so it's very similar. For the most part, everything I say in this lecture about TB4 can be applied to TB500. So the difference between BPC-157 and TB500 is found in this video. FYI, we don't like that combination product, as TB500 does not absorb orally very well. So we only use BPC-157 in oral form, and tb500 in injectable form. We use the BPC-157 capsules from InfiniWell as they use the arginate salt. To help out, we have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20). Once on that website, click the InfiniWell link, and then choose the product labeled 'BPC-157'. When you hover over the product, you will see it says 'Original Formula' above the ingredient box). This is the version that does not have SNAC, which we find works better.
Hey Drew, from what I’ve gathered, you say bpc injection is not site specific. This differs from a lot of info I see online, do you think I would see any benefit from injecting subcutaneous on the site as opposed to in the abdomen, etc?
No you wouldn't benefit from that. Too many people online who have never used BPC in more than themselves or a few people have opinions that are incorrect. I've used BPC in several hundred people and have read just about every single research paper on BPC - abdomen is equal to subq over the site of pain
Dr. Timmermans, thank you for this extremely educational lecture. I recently had a traumatic injury resulting in a complete tear of my acl ligament. I plan on using peptide therapy for my recovery post procedure. I plan to use bpc-157, thymosin b4, and mk677 in combination to assist in my recovery. Does this sound right to you? Is it true that thymosin b4 frag cannot be administered via a capsule due to its instability in gastric juices?
Hi Doc, Thankyou for this video. I am currently on my second week of taking BPC 157 every second day .20ml, TB500 five days a week .10ml, and cjc1295/ impamorellin 5 days a week .10ml, I am curious how long it takes to build up in the body and have an effect? I am treating tennis elbow and have been advised by a doctor to not inject near the injury only the stomach? Do you agree with his prescribed dose and advise?Thankyou for your time.
Most people will see effects within 4-6 weeks. Your doctor is correct, you don't need to inject near the area of pain/injury. In the stomach is easiest and works just as well
Timestamps
BPC-157 @5:36
Thymosin B4 @17:07
GH Secretagogues @25:37
Pentosan Polysulfate Sodium (PPS) @39:53
Tying it all together @48:18
For those looking to try BPC-157, this is the current product I use personally and recommend for my patients, as it is the stable form of BPC-157: bit.ly/3kxMmYg
Hi dr Timmermans, i’m From Belgium and my doc here wants me to try the BPC-157 for chronic ibs but he doesnt know where to get good capsules in Europe!?
@@nefilaswanson3187 sorry I dont have any good sources in europe.
Which peptide for sprains and strains of ligaments could you stack BPC-157 and TB 500 together?
If I had a sprained ligament (we dont strain ligament we strain muscles), i would personally use BPC-157, Tb4, and modGRF + Ipamorelin.
Hey drew, recovering from a accident recently with bad facial injuries, b4 the accident i was taking cjc1295. Do u think it would help with healing process quicker?
Absolute best thing I've ever seen on RUclips concerning peptides.
And I'm currently working on an updated lecture!
@@DrewTimmermansND I can't wait!
I’ve gotten to the age where my body is making me watch an hour of peptide talk. 🤦🏻♂️ it all happened so fast 😢😂
You are still here maybe you should be thankful for that
Lmao same. Who am I?? This wasn’t me a year ago lol.
@@GiGi-dd5cr hits you over night it does seem. I just wish I can sleep on my stomach with my leg hiked up 😂
Same tendon repair next week and I’m here for ANY and All things to help my quickly aging body heal ASAP
@@texasmom76 get yourself some mk677
Oral BP157 put my Microscopic Colitis in remission. I so wish more doctors were educated in this. It would save so much suffering.
Thats so amazing to hear
@@DrewTimmermansND and amazing to experience!
Which oral BPC did you use?
This is the one we use personally and for all patients: bit.ly/2WsJtby
@@DrewTimmermansND what about the bpc 157 cream?? Is that for spot treatment to the area for muscle , joint, tendon etc...or just wound healing? Thanks for all your videos.
My father has had many back surgeries in his lifetime, and unfortunately, he is constantly in pain or discomfort. I sent him a few videos on BPC 157 and TB-500. He's 72 this year and overweight. He cant exercise because of his pain, so it's extra hard for him to lose weight. He hasn't said anything about yet. And he's old school and would probably be a hard sell. Man, I wish he would just give it a shot. There really aren't any harmful side effects either. I'll have to send him this video. Thanks Dr!
I hope it helps him!
Liking and commenting so that this hopefully hits the algorithm and more people will find it - this is the best compilation on the topic out there.
Appreciate that ❤
I’ve very impressed with Dr Timmermans, a Dr that’s not pro phama, and listens to the patient in terms of their body.
I'm pro pharma in very specific circumstances, but not globally across the board. I think that's an important distinction to make!
He’s not pro-abuseofpower,😉.
Outstanding! PhD level lecture on super-exciting topic.
Tremendously valuable.
Thanks.
Appreciate those kind words 🙏
One of the very few podcasts that has inspired me to take notes. 👍
Great to hear!
Super intelligent and an amazingly interesting doctor.
One of the best informative presentations I’ve seen.
Glad you enjoyed it!
So good i had to watch it twice .. thanks doc. !
Appreciate that!
Drew, Thank you for doing these videos. My dad had a stroke. He's stuck in sub standard inpatient rehab facility. I'm using your videos to educate him and get him to try and heal faster and get home faster.
Hello Joe, any experience you can share now?
I have hole in my heart that produced a blood clot & essentially a stroke last week. Everything was fine but my upper left peripheral vision is screwed. Funny enough, I have bpc157 in my fridge that i ordered before the stroke. I'm familiar w/ the bpc157 study on stroke induced rats that showed remarkable brain recovery. I'm still a bit timid to take it because I don't want to make things worse or have some drug interaction as dr's put me on eliquis & a beta-blocker until I get my heart repaired. Would love more of my vision back though. Would love to know more.
Extremely good presentation 👍👍👍 I used bpc 157 and tb500 as well as mk677 a lot and with a lot of success. I did it on my own thought. 😅
Did u have any side effects at all?
I have leaky gut and ibs can i use it
@visionsno yes it can help those conditions. We use the InfiniWell brand as they use the arginate salt. We specifically use the Rapid Pro capsules. We have a 20% patient discount code on our website regenerativeperformance.com/supplements
Did you heal fully? You use injectables? Can you link where you bought?
This Dr. gets it. He is not afraid to step beyond establishment hash-lines. He is more for attacking the problem and addressing it than masking it through pharmaceutical meds and unnecessary surgeries.
Question: I ordered the HEALTH BPC 157 capsules. Would I get more benefit by opening the capsule and doing it sublingually first before ingestion or not?
Appreciate those kind words.
That approach wouldn't hurt, but not sure how much it would help as I dont know if the buccal absorption is good or not with the capsule formulation.
Im going to try this to help me with neurological damage from Gullian-Barre Syndrome, excited to try
This is the oral version we recommend in case you didn't see the pinned comment - bit.ly/3gTNrEI
This video cleared up some misconceptions out there on several different peptides. I now know the difference between some of them, which is going to make my next order more targeted to my goals. Thank you very much for the detailed explanations of these peptides.
My absolute pleasure
Great information here Doc!
Welcome to the future ladies and gentlemen. Peptides are awesome!
BPC-157 @5:40
Thymosin B4 @18:30
GH Secretagogues @26:11
Thanks for the timestamps man! Always forget about that
I find myself watching you nightly now. Just started BPC-157 for horrible shoulder pain an hour ago and might stack it with TB500. I truly enjoy your lectures, and if you were in my state ( I don't know, maybe you are) you would be my PCP. Thank you!
I hope that helps clear up your pain!
I’m interested in starting this myself. Are you mixing it together and injecting it? I’m curious if it matters where on your body you administer tb 500
How were your results?
@@skmg2888 Thanks for asking. I never ran the TB500 but I did run the 157 for a while. I also stopped benching and trained my chest with another means. I am about 80% better. I'll take that. It rarely bothers me now. I need to stay away form most side lateral movements and bench presses except on rare occasion, and I'm golden. I also used a lot of red light therapy which I still use. I think that played a big part as well.
@@nuclearkamikaze Yes, I reconstituted and injected it using bacteriostatic water. I thought about adding it in as an oral as well, seeing as how it is one peptide that you can, but I found that not to be cost effective. I also chose the sub q route for injection site in the effected deltoid. Even though it is considered a "smart peptide" and is said to find it's way to the area that needs increased blood flow for healing, I went as close as possible. If I had a knee issue, I would have gone close to the knee. It just makes sense to me.
Excellent as I have a possible upcoming surgery and looking at peptide to aid in recovery.
Awesome video. Currently using BP-157 and TB-500 after 2 PRP shots for my gluteal tendinopathy. Slow progress but getting there...
Updates?
Gluteal tendonopathy… this is interesting… what are your symptoms? I hope your well!
Hey mate, any updates? I got a gluteal tendinopathy too, been using tb4, any progress?
@@MrSqu1shy can u link me real TB-4 to buy online?
Thank you for this video I feel like this was the best one I’ve watched and I’ve watched a lot. I’m starting a daily oral dose of BPC 157 in a few days to help with some nagging golfers elbow and a few other injuries. I think I’m gonna take it for one month early and see how I feel then I might even try a month of injecting it close to the golfers elbow.That was recommended by a doctor to start orally he thinks I’ll see results within two weeks I’m pretty excited nagging injuries have slowed me down a lot in the last few years I’m excited to heal them up.
My pleasure man! And I'm excited to hear of your results!
Yes please share your experience with us here! Best of luck!
What's the brand of your bpc and where can I buy this sir? Thanks lot
This is the only oral one we recommend: bit.ly/2WsJtby
How did it work out for you?
Thanks for making this public. My life is trial and error with health issues. When I was a kid I took shots of HGH due to pituitary issues. Around age 13 I had extreme anxiety and depression and insomnia. Basically had that ever since (nearly 40 now) and have tried various antidepressants, TMS, Ketamine..everything. Then I stumbled on Selank and it worked better than anything I've tried. Not sure why the doctors didn't go for more pituitary focused methods but what one country approves of another sees as useless I guess. Only thing I'm trying to figure out is the physicality with Selank. Can't find much information on it. SSRIs definitely slowed me down for certain workouts (martial arts for instance) and I can't tell if Selank is doing something similar or if it's actually helping coordination/power output. I also have hypermobile joints (last SSRI helped me tear my right shoulder) so might look into the BPC for that. Doing experiments
I'm terribly sorry to hear that. It may be worth researching and exploring cervical instability especially if you are hypermobile, as this can cause a whole host of central neurological issues. No idea if that's your case, but might be worth exploring.
Is Selank a prescription? or OTC ?
I have hEDS and about to research peptides.
Not a fan of ND, but this guy really appeared to know his stuff…. Very impressed
Not all NDs are created equal. Appreciate the comment
@@DrewTimmermansND You familiar with Dr Heather Smith Fernandez ?
No, just looked her up. Haven't ever heard of her
@@DrewTimmermansND she down in Florida, has a large wellness clinic….. she created the practice terms Peptologist, Peptology…… Even offers a “certification”and ways to incorporate and market peptides into ones practice.
It's great to see that more doctors are using peptides more and getting the message out that they can help. I think it's a little much for us to start adding these terms to them, especially because the word peptide does not just apply to the medical peptides we use. A peptide is just a sequence of amino acids, and is ubiquitous throughout biology and physiology. I've been studying peptides for 9 years now, back when you had to find obscure forums to even learn about them because no doctors were even using them that long ago.
Thank you so much for putting out this information. It is tremendously valuable!
My absolute pleasure
Hi! Thank you so much for your channel. I just wanted to introduce myself, Dr. Maisam Hasan, currently practicing in California!
Pleasure to meet you!
I have arthritis just above the sinus tarsi area in my left ankle. For about 7 years, I've been dealing with burning, prickling, stabbing inflammation pain that would become more pronounced with certain weather patterns. So I had 2 Prolotherapy injections and then 1 PRP injection.
It helped, but I was still having many bad days. So I opted to try one more aggressive round including the following protocol...
(1) another PRP injection with AOD9604 +HA peptide
(2.) The following 3 weeks, one injection per week of AOD9604 + HA peptide
(3.) .15ml of BPC-157/TB-500 blend injected daily into my ankle for 3-4 weeks.
We'll see what happens...
I hope you see the healing you deserve!
Hi how was the result ? Hope u healed perfectly
Hi Doc,
Excellent lecture!
I know, and I studied quite a lot about peptides, hormone optimization, PEDs, and overall fitness pharmacology. I've also been experimenting with most of those myself for longevity and anti-aging purposes. Furthermore, I'm self-taught. Could you please recommend me a career path that I could undertake with all this knowledge at my disposal? I truly know a lot, and most endocrinologists I confront myself with are always impressed however I'm not interested in a degree as MD, so I lately considered a B.Sc. (Hons) in Health Sciences. However, I'm not quite sure if it does even exist a Master's Degree in Peptides or in Hormone Optimization that I could undertake afterward with such a degree. Moreover, I study these for fun and because I'm actually very good at it, but this is not my main work field. I do also know quite a lot about nutrition, and training, but that's not a career I'd like to pursue. Please, any advice would be very much appreciated from an expert in this sector.
great question man. Currently, there aren't any formal university/college degrees in peptides. Have you considered looking into becoming a naturopathic doctor (the type of doctor I am)?
@I know a…. You might consider getting to know the studies about the eight essential glyconutrients that make our stem cells. There is no endo system without them, and you won’t get the true story from med school. They run the show from the bottom up pretty much. Without these eight saccharides at the very minimum, there is no making, repairing, regenerating or messaging of other parts of our biology physically. So there are many devotees going into the study of glyconutrition. In conventional medicine, immunologists are informed about them, but for lucrative business’s sake, they are taught to keep it mum that you get get your own stem cell treatments from your own kitchen. Beware of the wiles of the conventional thinking ones-the ones who will ONLY think the way they were orogrammed in med school where 70% of their med school curriculum is actually written by drug company employees who aren’t even doctors (that is actually a true fact). I’d save that for if you ever need a busted leg set. For “all things immunity and degenerative”, look to glyconutrition. Only ONE food group can make stem cells. Carbohydrates. Why do you think there is so much propaganda against them by the conventional medicine set? If we are missing even one essential glyconutrient, we are in trouble, and a lot of us are in trouble. When we add it back into the diet, we now have all eight glycos in order to make the stem cells we need and also in order for cell to cell communication that would be flawed if even one missing. MIT calls glyconutrients “the missing food group”. There are books about this, like “Sugars that Heal”, and “Glyconutrients”, and “Miracle Sugars”. I have used these for many years, but don’t expect to get answers from your conventional doctors about them-it was mostly kept from them during med school, other wise, they wouldn’t serve the drug companies. Take care of yourself so you can take care of others. There are powers that be who would attempt to stop you from learning about this. God bless you in your journey. (Copy’d b4 pst)
Thank you thank you thank you for this video
I can't thank you enough
My pleasure
Awesome lecture. I'm born in London. Fellow Canuck in the States... Picked up the accent:)
I love it! Good catch 😀. Not sure if you looked into my background but I was born in Strathroy and went to Western for my undergrad.
@@DrewTimmermansND I saw you wnet to western. I'm from Ottawa and moved to Maryland in 99'. Cheers. I've been looking into Peptides SARMS as of late. Thank you for sharing this valuable information.
Awesome content, thank you
My pleasure!
At 33:06, I guess there's a mistake. CJC-1295 isn't sermorelin.
- The origin GHRH contains 44 amino acid
- Sermorelin contains the unmodified first 29 amino acids of the origin GHRH, also called GRF 1-29 (half-life shorter than 10 min)
- Mod GRF 1-29 is a modified sermorelin, where 4 amino acids were replaced, also called CJC w/o DAC (half-life arround 30 min)
- CJC-1295 is also a modified sermorelin, but with an added "DAC" instead of replacing amino acids, also called CJC w/ DAC (half-life about a week)
Correct me if i'm wrong.
You are correct and I was mistaken in the video. Good catch!
Well done
Wow thanks Doc. This is one of the best lectures I’ve seen on these peptides! For some reason injecting CJC + ipamorelin before bed gives me issues as well. It’s like a slightly elevated heart rate with a heavy pounding sensation. Nothing crazy but enough to keep me up, which is strange because supposedly these peptides don’t raise cortisol. It doesn’t seem to happen every time though. If I take it during the day it’s not noticeable whatsoever.
Also, any chance you’ve delved into GHK-Cu in another video?
Glad you enjoyed it! I haven't yet done a deep dive video, but it will be included in my next lecture on peptides!
Sorry, do you inject yourself for OA?? I’m intrigued
Ipamorelin can like other HGH substances, can decrease insulin sensitivity and have your blood sugar raise. In your youth you were likely more active and your body acting youthful and you not utilizing the energy likely has a surplus at night.. probably damaging for your pancreas. Just a guess... Based on information from forums on the subject.
Dr T, will you please to a video on tesamorelin and the benefits of adding it as the ghrh to ipamorelin? Thank you and love your videos. I have learned a ton
That video will be made at some point!
Thank you very much for the great information. I’d love to interview you on our podcast about martial arts and mental health. There’s a ton of people in my audience who want to learn more about this topic
Thank you for the offer. Unfortunately due to current FDA restrictions on peptides and therefore it's near impossible to get these peptides from a compounding pharmacy, I'm not doing podcasts on peptides at this time. Additionally, mental health is not my area of focus. Thank you
@@DrewTimmermansND sounds good ! Keep doing the great content and I’ll send people your way
Hello, this was a very helpful video and very thorough regarding peptides. I myself had an accident in gymnastics and I tore all of my ligaments in my left knee. I also tore my biceps muscle and have a small indent in my bone..so yea it was a pretty bad injury and being an athlete I searched for all the Best practices and medicines regarding post-op regeneration and rehabilitation and then I stumbeled on peptides. I am already interested into taking BPC and I will Use all the recommendation you have listed, But my only question is when to take it? Thank you for the great content and spreading the awareness of the great use of peptides
I'm terribly sorry to hear that. If peptides don't resolve your issues 100%, it may be worth looking into a consultation for regenerative injections. We dose oral BPC-157 once per day for most people, taken with food
Thank you very much for the answer. I am on my own with this one because in my country it not common to cooperate with doctors with regeneration methods. So thank you for this kind of content for those who don't have other means
My pleasure 🙌
Stupid question, what role does the lack of Bpc 157 play in respect to chronic inflammation?
Wow, this is great! Thanks for sharing! I am currently 7 weeks out from ACDF surgery and was recently prescribed TB4 to aid in my recovery process. I just started today so I can't say definitively that it has helped but my hope is that it will help primarily with the weakness I still have from the nerve damage. Do you think this will help speed up the process of nerve regeneration? Thanks!
That's great to hear! I can't say in your case as I don't know the details of your case, but peptides have amazing capabilities to help patients heal
Amazing lecture thanks much!
Just saw a video from 3 yrs ago that SKorea found a peptide to help RA. That brought me to your video. Do you do any work with RA patients (of course they are doing it overseas!!). My 81yo Dad just diagnosed with RA though I’m sure he’s had it for years (5 joint replacements in 5 yrs). Do you think allopathic medicine will ‘prescribe’ peptides for pain?
So informative! Thank you Brotha
My pleasure
Have no pain, would like recommendations on Anti aging peptides
Thanks
Thanks for watching. Anti-aging peptides are not my primary area of specialty so I don't speak about them. Other youtube accounts might be better for you
Great job with the presentation here!
Thank you!
Hi Drew. I’ve been doing Prolotherapy since 1995, PRP, since 2007, and bone marrow & adipose stem cell treatments since 2008. But I’m brand new to peptides. This is an excellent lecture! Very clear and informative. However, this lecture was 3 years ago. Has your treatment algorithm changed since then regarding dosing / usage?
have u heard of prolozone - prolo with ozone result is suppose to be good and cheap compare to prp and stem cell
Dr Timmermans would you be able to help a 10 year old neutered male 50 aussi shepherd (dog) with a pretty advanced trigon bladder cancer. Thanks and bless you
I'm not a vet, so no I can't. Sorry
Would you consider using CANNABIS OIL as it has phenomenal effects on humans with even extremely advanced stage 4 Cancer.
Not HEMP derived CBD oil, but Cannabis derived oil in the treatment
So I have seen many recommendations for Tailor Made Health by reputable people, like you, but I found a complaint filed against them by the FDA in 2020 for, among other things, unsanitary conditions. I am just wondering if you have some insight that leads you to this recommendation because I don't know who to trust for purchasing BPC-157.
I degloved my ring finger about a week ago in the gym , crushed it in between two dumbbells, i started BPC 157 and TB 500 two days ago and i hope to god it works and speeds up the recovery , nail was ripped off and fingertip broken too , end was degloved so i am hoping for new cellular growth for my fingertip please help 😢
damn! I hope you have a speedy recovery
Hey Drew,
Appreciate the content. Have been researching various peptides over the past 8 months with an interest in healing and recovery. I enjoy reading the studies and breaking down the data. As this is still very underground in comparison to conventional or western medicine there are many nuances. I believe hormonal and or naturopathic clinics will certainly be the go to in terms of guidance and transparency as they have clinical tools and knowledge as well as access to compounding pharmacies. In the description you've provided a link to DNA health and I was wondering if you knew where they sourced their peptides from, maybe a specific compounding pharmacy?
Best,
Drew
Hey Drew, DNA Health is a supplement company therefore they don't purchase raw materials from compounding pharmacies. They own the patent for BPC-157 arginate salt. I don't know who actually produces that.
Think I'll be trying some BPC-157 to counteract the nasty side effects from Accutane. I can't even run anymore because of accutane, nasty stuff.
Ugh that sucks, keep us posted!
What is the major difference between rapid release and delayed release of BPC-157? In other words, why would someone pick one over the other?
Delayed release stays in the gut longer so it appears to have better effect on the gut and GI system. We use rapid for our orthopedic pain cases
Amazing video. Would any of these be helpful for a person that deals with multiple issues related to old TBI injuries? Migraine, nausea, chronic fatigue, etc? Thanks again for the video. 🙏🏻 Watched this twice now, such valuable info.
BPC-157 can be helpful for chronic neurological conditions, but it's not something I personally do a lot of
@@DrewTimmermansND you don't do a lot of work with TBI or you don't use BPC-157? Please specify
I personally don't work with TBI patients, my wife (another ND in our practice) sees those patients. She uses BPC-157 for her patients with TBI
Heck yes!!! More vids like this!! 👏👏
Question: with the GHRP & GHRH, do you need to take a break from these compounds after a few months? Or can you use it continuously? If so, does the cycle vary by the amount used?
Glad to know you appreciated the video!
It depends on how frequently you're doing the secretagogues. If you're just pinning once per day, if you take one day off per week most people can continue for 6-12 months without any evidence of negative effects. We don't necessarily recommend that though, as we believe that humans evolved to have periods of fasting and feasting. So if someone does GH or GHS for several months, we intentionally want to scale back all anabolic substances and approaches for a few months as well.
@@DrewTimmermansND Understood. Thanks!
Thanks for sharing.
Did you say that Sub-Q injections are pointless due to the peptide being absorbed by the bloodstream anyways?
They aren't 'pointless', but they don't provide an advantage over oral for most patients. Some patients still respond better to injectable, just not a large majority.
SubQ injections over the area of pain is pointless
Anyone know the side effects to coming off BPC or TB4? Is there any backlash in the body?
Thank you so much for posting this video. I found it to be very helpful. Could you recommend a site for purchasing tb 4?
My pleasure.
We only recommend compounding pharmacies, and they can't get tb4 anymore because of the fda. Sorry
Hey Doc! Rock climber here. I'm currently supplementing BPC-157 and Thymosin Beta-4 to treat a labrum tear. I have them both in a nasal spray application, I was wondering, what dosage should I be taking of each? I've done tons of searching but with no luck.
This video is literally a video that talks about dosing! Our standard dose is 500mcg per day of BPC-157 and 750mcg per day of tb4
Do you have any updates on the labrum tear?
I'm two bottles in with bpc 157 for my shoulder IAM 57 work full-time in a metal shop work out 5 days a week my right shoulder either has arthritis or a rotator cuff injury they did x-rays and that's what they determine getting cortisone shots which helped for two months and I'm tired of it and I got enough bpc-157 6 to 8 wkks IAM happy with it so far 🤞💪😉
super happy to hear the BPC-157 is helping you!
do you have a good site to get it the quality of the product is super important well it's everything LOL
We use the Infiniwell brand as it's arginate salt. You can find our discount code here - regenerativeperformance.com/supplements
@@DrewTimmermansND thanks for the information how long is your recommended dosage and how and if it works what's that time line look like thank you
We usually do 500mcg oral. If the patient is getting better at 2 months then we continue until they are no longer getting better (also called a plateau). Then we reassess.
Thanks for great content
Thanks for watching!
Dr T, will any of these peptides help neuropathy?
If you need a human lab rat, I have AS and am more than willing to let you experiment. Lol
Hey Drew! Loved this in depth lecture. Since the BPC 157 on infiniwell is currently sold out, would you recommend the rapid or delayed release to help aid elbow tendinitis & a wrist sprain? What pros/cons do each one have?
Thanks
And also if taking in the morning, would it be best to eat right after ingesting, or waiting for some time.
We only use the rapid, as that's what all the research has been done on.
If taking in the morning wait 30 mins before eating
so what tends to be better for post operative healing from orthopedic surgery. ? ….. TB4 or BPC ?
depends on the patient. Most commonly BPC-157, but usually I like to stack both
Hi Doctor thanks for the info. Do you think that BPC 157 would be helpful after a full hip replacement (4 weeks ago), or at least worth discussing with my surgeon? I am a 28 year old male and generally healthy, replacement was done due to avascular necrosis . We were not able to identify the cause of the avascular necrosis. I have also been experiencing pain in my right shoulder for years, same side as hip. If I do want to talk to my doctor should I consult my GP or surgeon? Thank you so much in advance for any help in this regard.
So much great information. Thank you for helping the community 🤙 When you say that BPC is produced by our bodies naturally, does the amount of our natural BPC decrease as we age like hgh does and that's why we should supplement it? Or does it remain at more consistent levels throughout our lives?
My pleasure, thank you for those kind words. We unfortunately don't really know anything about the natural production over life as those studies haven't been done.
@@DrewTimmermansND Well somebody needs to get on it! 😂 Ok thanks 👍
I don't get how we came to 250-500mcg/d on BPC 157. Why don't we go higher? Why not longer? Not any evidence of cancer in rodent models
Hey! The 250-500mcg/d dose for BPC 157(vitalbpc157) is based on limited human data and rodent studies. Higher doses or longer use could have unknown risks since it's not well-researched in humans yet. Better to stay cautious and wait for more research to ensure safety.
@@PamelaShine-q8e in that case, why take it at all? Avoids all of the risk, especially considering how little data there is in humans
@@troy3423well if you can’t afford and need healing you may not be able to wait. But generally they block research if it will help people. The places that fund the research won’t fund it if it isn’t a money maker and I think peptides you can’t really patent.
There are risks with everything but verbally many have taken this without issue so at some level that is a test even if there are less controls in place.
But if you’re waiting for the major groups that do research to research a thing they can’t patent and profit off of I doubt that will happen anytime soon.
There are risks with anything you take. So you research and try to assess that and decide if the risks are acceptable. But for those in pain if they see many benefit form a thing and have no assurance research will be done this century it’s maybe not enough to tell them to just wait and hope as their body degenerates.
Hi Doc, how effective is BPC-157 with recovery in peripheral nerve damage to the legs/feet? I Believe I have the
Acute motor axonal neuropathy (AMAN) variant of Guillain Barré Syndrome and was wondering if this peptide would speed up my recovery!?
Or do you think an IGF-1 secretagogue like MK677 would be more beneficial?
I think between those two, BPC-157 has a better chance of helping.
What would be your recommended dosage and frequency of BPC-157 & TB-500 Blend (10mg) injections for a college football athlete with a torn labrum (shoulder)?
This video has generalized dosing. For individualized dosing approaches, you would need to become a patient so we can put together a full protocol that is specific to you and your case.
Hello Dr. Timmermans, I contacted you on here although I don't see it here to ask of you knew someone in Vancouver to give me shots of Thymosin B4 and you replied nobody. So I was wondering how much I need for torn cartilage and for how long. After listening it sounds like I would do the 750mcg,(.25ml) daily for 20 days. Can I get a nurse to inject this? And does it go into the fatty soft tissue? between the bone? How much would I need for 20 days?
Sorry I don't know anyone in that area that can give you shots. On average we use 750mcg for 20 days in a cycle. Most patients get the product and then inject it at home into the subQ tissue
@@DrewTimmermansND Yes, thank you did get the original message of nobody in my area. Okay you just confirmed what I wanted to double check. Glad you have been on here and available for consulting.
Dr. Timmerman, I have a thumb that got bent back and doesn't want to fully heal, and rotator cuff that prevents me from pitching baseballs to my sons and I also had a recent brush with frostnip that caused the circulation in my feet and toes to decrease. Do you think BPC-157 might help me with some of these problems? Thank you so much for your wonderful work!! :)
We find BPC-157 helps about 70% of people when you lump all ortho conditions together. So I'd give it 70% chance. Make sure you use a good form though. We use the BPC-157 capsules from InfiniWell as they use the arginate salt. To help out, we have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20). Once on that website, click the InfiniWell link, and then choose the product labeled 'BPC-157'. When you hover over the product, you will see it says 'Original Formula' above the ingredient box). This is the version that does not have SNAC, which we find works better.
Hello Doc, thanks for the great lecture I’m just wondering when you said BPC in clinical practice worked better in combination with a stimulus. Would ART (active release technique) be a good stimulus? Or isolated exercises in the gym work? Can you also explain what ‘guasha’ is? the first stimulus you mentioned. Thanks again in advance.
Regards,
Jack
Guasha is Chinese medicine scraping. ART and exercise can be a stimulus yes. That may or may not be strong enough for an individual.
You should only ask questions you can't find answers for before asking foolish questions is an insult & waste of time to a doctor of his caliber
Great lecture, I learned a lot… But you kind of lost me at 39 minutes 44 seconds when you mentioned the “anabolic window” 😳 do you believe this exists?
No my thinking has evolved since then. I still believe for some people it may be important to get protein/calories in asap after exercise because it allows for more calories or protein to be consumed within a 24 hour window though.
Would peptides help heal c section incision that is slow healing? I have holes in my incision with drainage. Are the peptides breastfeeding safe?
Unfortunately peptides have not been tested in pregnant and lactating women, so we do not recommend this.
Outstanding video, thank you. One question about the HGH quantity released by using GHRH+GHRP. Economically and quantity wise speaking, is it more convenient use straight HGH or is it better use GHRH+GHRP? To how many UI of HGH would be equivalent use 200mcg GHRH + 200 mcg GHRP? I mean, what if I just directly use HGH injections of 2 UI daily?
This is amazing thank you but great ghost of Space Ghost that is a bottomless thermos of distraction. Is anyone else's misophonia screaming?
Hi Dr Timmermans, I have just had a chat to Infiniwell as I saw you posted their link in another comment. Sadly they don’t ship to Aus. I was wondering if you knew a reliable company that ships to Australia for BPC-157 capsules?
Hey man, unfortunately I don't have any trusted suppliers to AUS
@@DrewTimmermansND NO dramas mate, thanks for the response!
The only thing i would like to add due to personal experience i took bpc157 from a good source in capsules to heal ligaments and it did nothing, it needs to be injected as close as possible to the injury. It does make a world of difference.
Some people do not respond to oral and they respond to injectable, and vice versa. I'm glad you found what worked for you!
But to clarify as we have worked with over 500 people with BPC-157 at this point, and your statement is not true for most people. Be careful telling people that the only way something will work is what worked for you, because that's not true for everyone.
Majority of people see outstanding results with oral BPC-157 and they do not need to inject it. Some people do need to, but most people will see significant benefits from oral.
@@DrewTimmermansND the vote is still out for ligament laxity, i got prolo and PRP but now my sport doc is on a break trying to fix what is left with the peptides. To be honest even sub Q tb500 and bpc not sure its going to work for ligament laxity, i do feel better my hips are stronger but i still get some groin pain. I will be on about 6 months, i am 1 month in. Also using cjc and ipa and added 1 month cycle of IGF1 LR3
Best of luck to you!! I hope the peptides help resolve your issues
"I'll tell you this: everybody has something they'll respond to better. Some people do respond better to oral... I trust the patient's intution. If the patient comes and says, 'You know what, I think I'm going to have a better response with oral'... then I say, 'Alright, we're doing oral.' If they don't... I tell them to do oral, because then you don't have to worry about syringes and needles and it's just a nice easy... oral." -- Drew Timmermans ND
I don't know if I've ever been quoted before! 🤣🤣 I love it 🙌
@@DrewTimmermansND There's much wisdom in that quote. I suggest you make a picture with that quote written in a cool font (I suggest the Led Zeppelin font) next to a photo of you in a majestic pose and that you post it often on social media. As your pro bono attorney I guarantee you this will be good for your career.
P.S. It'll also be a good career move for you to pin these comments to the top.
Isn't that just letting the patient choose their own placebo effect?
Sometimes, yes of course. I've still seen enough times where patients were indifferent and one form did better than the other, so i don't believe it's all the time.
I'm happy if they get a bigger effect because part of it is placebo. They get more healing and I am okay with that 😉
🤣🤣🤣 that's a good idea.
I also always forget about pinning comments to the top! I definitely need to do that more
So in case I missed it. For BCP-157, would injuries be a stimulus? I suffer from hEDS and I am in amazing shape through years of hard work but soft tissues always hurt regardless of any modalities used i.e physical therapy.
Yes, an injury would be considered a stimulus
I Have TERRIBLE 'Brain Fog'!!... :( *WHAT IS BEST TO CURE THAT,Dr Timmermans??.... :)
Find the root cause and then treat the root cause. That's the only way to cure it
@@DrewTimmermansND - H-O-W Do I Do that?.... :)
Hi Doc,
I have intermittent hydrathrosis (my knees swell one week out of 2 without any damage on MRI) I have a CRP about 12.
What would you recommend me to try ?
Thank you for sharing your knowledge with us, it s so interesting
I'm sorry but I can't provide specific recommendations for you to try unless you become a patient of mine. If you'd like to look into this further, you can find more information here regenerativeperformance.com/contact. Our goal is to get to the root cause of why you are having these symptoms so that we can provide personalized treatment recommendations for you, which address the root cause.
Hi Doc, great info and lecture! I just ordere BCP 157, had motorcycle accident and broke both of my hand wrists, tendons and ligaments injured as well. I want to go back to training, please can you tell me if I need to administer injections on both injury spots, should i split the daily dose in that case or not? Thank you in advance!
Would it be good to stack it with Ibutamoren (please note that my family have history of cancer illnesses)
Hey man, I cant give you advice on what to stack that with. If you're going to inject the BPC-157, you only have to do it in one spot, and the abdomen works perfect
@@DrewTimmermansND Thank you so much for fast reply! Just one more question if you find time - Since I've read all around that it is better to administer dose 1-2 cm from injured spot, should I administer it like that, or to stomach like HCG since I have couple of injuries! Thank you!!
Injecting close to the site of injury is bro science and isn't actually true. Some may get placebo effect from that, but it goes systemic almost immediately after injection, so just into your belly is great
@@DrewTimmermansND Very useful information, will do like that. Thank you for your time again!
Great video, thanks for the amazing content. Does Mod GRF 1-29 combined with Ipamorelin lead to typical side effects from elevated GH levels? Let´s say for the dosing of Super Saiyan Effects. I can´t find anything about that issue and am wondering why they warn about so much side effects for HGH injection (in short: growth of everything) but for the peptide use this does not occur? Thanks a lot!
It's extremely rare to see those side effects that are commonly attributed to exogenous GH, but they can happen.
@@DrewTimmermansND Thank you for that quick answer, that is very much appreciated.
Would you need to take a GHRP with MK-677 (Ibutamoren)?
To the camera man, for future use,
Just put up the slides of the slides
We don't need to see the presenter , it is just distracting. . ..
And when you draw back the slide fades to very light, and see it fasteniugh if I haven't memorized the slide in 20 seconds, LOL
THANK YOU . . .
Have you done any research on the so-called host defence peptides (HDPs; also called cationic antimicrobial peptides)..?
Only antimicrobial peptide I've used is LL37, but we haven't been able to get it for a while now
@@DrewTimmermansND bummer! It’s a very interesting time for peptides therapy. I hope you heal the world my friend.
Trying! One person at a time
Doc! Thanks for the video.
I’ve gone through two ACL‘s and torn meniscus. Both knees are just not good.
Been in pain for 10 years
I’ve done everything possible so far.
PRP, physiotherapy, massage, acupuncture and this last month was on BPC 157 but no effect
what can you recommend doc, can’t handle it no more
I'm terribly sorry to do that. Your case is unfortunately too advanced for some simple recommendations on youtube. These cases we would need to work one on one so we can get to the root cause. If you'd like to see if we're a good fit to work together, please fill out an application here - coda.io/form/Dr-Timmermans-Initial-Screening-Application_dLRPTx2mJ1T
@@DrewTimmermansND thx for the reply Doc. Will do!
Do you believe BPC-157 should be accompanied by anything, like TB-500 or TB4 Fragment? About the capsule form of combo BPC-157 & Thymosin B4 Fragment; is the fragment part (Ac-SDKP) of no use because it's capsule form? Do you have any opinion on infiniWell as a source?
Can any regenerative therapy like PRP, amniotic allografts, and peptides help nerve injuries and/or neuromas?
yes they can. We have successfully treated and resolved neuromas with PRP nerve hydrodissection and adipose stem cells. Would you like to explore working with us? If so, please reach out to my clinic! regenerativeperformance.com
Pretty sure there are numerous publications where they are trying to administer GHRH over prolonged periods (eg with an infusion pump), prior to the discovery of CJC-1295. In studies on CJC-1295 the authors often note that boosting the overall baseline is healthier and more physiologically relevant than giving these supraphysiological pulses with a bolus administration, and that bolus administration is the cause of the majority of GH related side effects. Do you have a scientific opinion on this? What you said about the benefit of bolus dosing around min 33-34 sounds very much like bro science and not what the literature says.
If you could share some references explicitly supporting short-acting bolus GHS dosing to achieve some type of benefit that is superior to longer term release, I would genuinely love to see them
Hey Dr Timmermans, what do you say to those "studies" that say that there is a risk of cancer associated with peptides to the angiogenesis? Id love to try tb4 to help a small ligament tear i have in my shoulder. And for ligaments and tendonitis would you recommand tb4 or bcp 157? Thanks!
Exercise increases angiogenesis, but it doesn't cause cancer. I haven't seen any studies showing increased cancer risk.
@@DrewTimmermansND thanks for your answer. For small ligament tear would you recommand tb4 or bcp157?
Usually BPC-157, unless there is a lot of fibrotic tissue, in which case tb4 tends to work a little better
Pretty niche information. Thank you!!
I have slip disc diagnosed. Majority pain is in the lower back right side and slightly into hip. I test positive in straight leg raise test for the right leg.
I'm usually fine even while Deadlifting and squatting. It gets severely aggravated after playing soccer where I have to change directions quickly and sprint fast too. The pain the next morning is quite debilitating in the low back and bending at all.
I have started bpc157 recently as no doctor deals with such methodologies in India.
Does tb4 fit my use case more than bpc? Or any other things you would suggest to your patients?
Appreciate that. Unfortunately I can't give you specific recommendations as you have to be a patient for me to do so.
the question of the day is ... where can you get a reliable source in Canada, that won't cost you an arm and a leg :P
? Great talk btw.
Oral BPC-157 from InfiniWell can be shipped to Canada! You can find our patient discount code on our website regenerativeperformance.com/supplements
@@DrewTimmermansND What about the TB 500?
That has to go through compounding pharmacy and I'm not aware of any in Canada that compound it
Drew, you mentioned "epicondylitis" and "epicondylosis". These are outdated words and have been outdated for over 15 years now. The correct terminology for both is "tendinopathy".
Respectfully, I'd have to disagree with you.
First, academic journals publish a great deal of articles using these terms, even in 2020. If they were truly outdated by 15 years this should be reflected in the research now.
Second, tendinopathy is a generalized term for pathology of a tendon. I personally dont agree with lumping two different pathologies (osis and itis) into one collective term, because pathology is different and treatment approaches should be different.
What do you make of the cancer potential of TB4 and tb500?
Does BPC-157 cause histamine reactions? Is TH B4 Frag better, been having stomach issues for quite some time.
Some people can have some histamine reactions from BPC-157 but we really only need to be cautious in people diagnosed with MCAS. BPC-157 is still better then tb4 for gut issues. If you're gonna do BPC-157 make sure you use a good quality arginate salt. We use the InfiniWell brand as they use the arginate salt. We specifically use the Original Formula capsules without the SNAC. We have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20).
I have the Integrative Peptides brand. What is the diffrence between with and without SNAC?@@DrewTimmermansND
Thank you doctor for the information you gave. I had an accident and still trying to recover from multiple conditions. What is the difference between TB500 and BPC 157. there is a product which is combination of two. which one we should choose.
I'm not sure which one you should choose, as I'm not your physician sorry. TB500 comes from TB4, so it's very similar. For the most part, everything I say in this lecture about TB4 can be applied to TB500. So the difference between BPC-157 and TB500 is found in this video.
FYI, we don't like that combination product, as TB500 does not absorb orally very well. So we only use BPC-157 in oral form, and tb500 in injectable form. We use the BPC-157 capsules from InfiniWell as they use the arginate salt. To help out, we have a 20% patient discount code on our website regenerativeperformance.com/supplements (code is RP20). Once on that website, click the InfiniWell link, and then choose the product labeled 'BPC-157'. When you hover over the product, you will see it says 'Original Formula' above the ingredient box). This is the version that does not have SNAC, which we find works better.
Is it ok to order abroad ? I live in Dubai. Does the products have to be stored in cold ?
Hey Drew, from what I’ve gathered, you say bpc injection is not site specific. This differs from a lot of info I see online, do you think I would see any benefit from injecting subcutaneous on the site as opposed to in the abdomen, etc?
No you wouldn't benefit from that. Too many people online who have never used BPC in more than themselves or a few people have opinions that are incorrect. I've used BPC in several hundred people and have read just about every single research paper on BPC - abdomen is equal to subq over the site of pain
Drew Timmermans, ND thanks so much, I wish this kind of information was more widely available than the broscience
I do too!
What do you think about GHK-Cu for injury healing?
quack quack quack
Dr. Timmermans, thank you for this extremely educational lecture. I recently had a traumatic injury resulting in a complete tear of my acl ligament. I plan on using peptide therapy for my recovery post procedure. I plan to use bpc-157, thymosin b4, and mk677 in combination to assist in my recovery. Does this sound right to you? Is it true that thymosin b4 frag cannot be administered via a capsule due to its instability in gastric juices?
That sounds like a really good stack. Other things we would consider: GHK-Cu, Vitamin C, collagen peptides, StemRegen.
How are you doing post surgery?
Hi Doc, Thankyou for this video. I am currently on my second week of taking BPC 157 every second day .20ml, TB500 five days a week .10ml, and cjc1295/ impamorellin 5 days a week .10ml, I am curious how long it takes to build up in the body and have an effect? I am treating tennis elbow and have been advised by a doctor to not inject near the injury only the stomach? Do you agree with his prescribed dose and advise?Thankyou for your time.
Most people will see effects within 4-6 weeks.
Your doctor is correct, you don't need to inject near the area of pain/injury. In the stomach is easiest and works just as well
Question,
Can you pull the BPC and TB into the same syringe? I'm about to start Saturday but have zero experience.