Methotrexate in Dermatology - Drug, Mechanism of Action, Use, Side-effects

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  • Опубликовано: 5 ноя 2024

Комментарии • 28

  • @fathisoobe7745
    @fathisoobe7745 Год назад +4

    Thank you very much sir, i hope you will also add dermatology diseases which let us to gain more of your experience. Very fruitful ved i have ever seen in RUclips. Thanks doctor

    • @sabhderma
      @sabhderma  Год назад

      Thanks for watching. Yes, I will be adding videos on clinical dermatology, and pathogenesis of various disorders in due time. 😊

  • @amygdala551
    @amygdala551 5 месяцев назад

    Amazing lecture sir. Will share with my friends also, This channel needs more viewers❤❤❤

    • @sabhderma
      @sabhderma  5 месяцев назад

      Thanks a ton. Please share the link to the channel among your friends. We will be continuing videos every week, covering important and esoteric topics in dermatology in an easy manner. Till then keep watching and sharing videos 😀😀

  • @shreyaskololgi1907
    @shreyaskololgi1907 7 месяцев назад

    Amazing lecture sir.. thank you soo much

    • @sabhderma
      @sabhderma  7 месяцев назад

      Most welcome 🤗🤗

  • @vikaspurushottam8542
    @vikaspurushottam8542 8 месяцев назад

    Thank you sir please complete leprosy series as soon as posible

    • @sabhderma
      @sabhderma  8 месяцев назад

      Surely, we will discuss leprosy in a stage wise and detailed manner. It is a very important aspect of dermatology and is filled with concepts that are improving to understand. ☺️☺️☺️

  • @دكتورهايفيتسوريال
    @دكتورهايفيتسوريال 3 месяца назад

    would you make a video about treatment of psoriasis in children please?

    • @sabhderma
      @sabhderma  3 месяца назад +1

      Thank you for commenting ☺️. There is a video where we discuss the use of biological therapy in psoriasis. We learn about British and American guidelines. It's there on the channel, you may want to see that. Let me know if that helps. 😊😊

  • @tushar2919
    @tushar2919 Год назад +1

    Thank you sir

    • @sabhderma
      @sabhderma  Год назад

      So nice of you to reply 😊😊

  • @shubhamchopra1099
    @shubhamchopra1099 Год назад

    Wonderfully Explained sir 🙏🙌🏻

  • @BasmaBasheer-p4x
    @BasmaBasheer-p4x 2 месяца назад

    Sir please do a video on jak stat inhibitors

    • @sabhderma
      @sabhderma  2 месяца назад

      Sure, I have added it to the suggestion list. Will make one on this topic. ☺️

  • @gryffindor5345
    @gryffindor5345 Год назад

    Thankyou sir very useful 😊

  • @khushbujadav4869
    @khushbujadav4869 Год назад

    Thank you so much sir🙂

  • @drarshadiqbal4220
    @drarshadiqbal4220 8 дней назад

    Is it true that 10 percent of methotrexate converts to the polyglutamate form? Is this not the case for 100 percent?

    • @sabhderma
      @sabhderma  2 дня назад

      That's a very good question. I have found varying %s of glutamate conversion. I am listing 1 reference below that mentions 52%. Just remember that polyglutamate residues do not leave the cell, but has the activity of MTX. You can read the below article.
      Kuehl M, Brixner DI, Broom AD, Avery TL, Blakley RL. Cytotoxicity, uptake, polyglutamate formation, and antileukemic effects of 8-deaza analogues of methotrexate and aminopterin in mice. Cancer Res. 1988 Mar 15;48(6):1481-8. PMID: 2449950.

  • @SadikshaAdhikari-x6n
    @SadikshaAdhikari-x6n 10 месяцев назад

    Sir..I would be grateful if you could upload basic dermalogy videos…

    • @sabhderma
      @sabhderma  10 месяцев назад +1

      Sure I will. 😊 We are currently doing a series on STI topics. Do watch those videos in the meantime. What all topics do you have in mind from basic Dermatology?

    • @SadikshaAdhikari-x6n
      @SadikshaAdhikari-x6n 10 месяцев назад

      @@sabhdermaThanks for your response..I am 1st year pg resident of Dermatology from Nepal..I am trying to make my concept clear on topic Cytokines…so it would be real help for me sir..

    • @amygdala551
      @amygdala551 5 месяцев назад

      ​@@sabhdermaanatomy of nail and hair is difficult sir. Tried to read from rooks, bolognia and Fitzpatrick but still not able to recollect, land up with a lot of difficult

  • @aye_puniya
    @aye_puniya Год назад

    Thank you sir :)

    • @sabhderma
      @sabhderma  Год назад

      Keep watching other videos too 😄