PROTEIN SYNTHESIS: A-level Biology. Transcription, translation and pre-mRNA modifications

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  • Опубликовано: 4 окт 2024

Комментарии • 133

  • @adxm0382
    @adxm0382 3 года назад +74

    Needed this, have my exam tomorrow. Another great video!

  • @epicfunnyvideos9289
    @epicfunnyvideos9289 Год назад +4

    Thank you so much for your efforts the explanation is excellent and finally now i understood what is happening

  • @lara3024
    @lara3024 3 года назад +15

    Great video! Everything’s explained really well, thank you!

  • @FriedaWilhelm
    @FriedaWilhelm 4 месяца назад +2

    Thank you miss estruch

  • @officialusherrunozivei
    @officialusherrunozivei Год назад +1

    Well explained I can't believe I understood today and I have my bio p2 exam tommorow

  • @reiwasaru
    @reiwasaru 10 месяцев назад +2

    I actually understand it now wow

  • @Wojbest_YT
    @Wojbest_YT 4 месяца назад +1

    you should have a beyond the spec section at the end for things beyond the spec but some people want to learn more i seen another channel do it

  • @domanidouglas9192
    @domanidouglas9192 3 года назад +2

    I have my exam in an hour!! Thank UUU

  • @harrydonna90677
    @harrydonna90677 2 года назад +2

    OH MY DAYYYYSSSS TY SM!!!! THIS HAS RLLY HELPEDXXXX

  • @gobi9783
    @gobi9783 2 года назад

    Redoing my paper 1 mock from year 12 on thursday crazy how i learnt this in like 10 mins

  • @daaragoodluck
    @daaragoodluck 4 года назад +3

    Your Vids are Great!

  • @tct5757
    @tct5757 4 месяца назад +1

    So helpful

  • @kayceelondon
    @kayceelondon 3 года назад +3

    great video!

  • @ajtv6208
    @ajtv6208 2 года назад

    Have my exam on Wednesday, amazing vid

    • @MissEstruchBiology
      @MissEstruchBiology  2 года назад

      Good luck!!

    • @ajtv6208
      @ajtv6208 2 года назад

      @@MissEstruchBiology i did alot better using your videos thank you !!! my teacher recommended you

  • @danix6452
    @danix6452 3 года назад +2

    Love this!!

  • @Nickuxx7
    @Nickuxx7 2 года назад +1

    i dont understand why for your method you say dna helicase unwinds the double helix but in other videos rna polymerase is joined at the start and the hydrogen bonds are broken ?? which is right

  • @BLACKWHITE-og3rg
    @BLACKWHITE-og3rg 10 месяцев назад

    thank u tea cher for explaining love u

  • @ryou6453
    @ryou6453 8 месяцев назад +1

    thanks!

  • @shannonharper2460
    @shannonharper2460 3 года назад +5

    How much would you recommend the workbook? Is it full of exam style questions or more useful for the preliminary learning stage? Many thanks for all your videos!!

    • @MissEstruchBiology
      @MissEstruchBiology  3 года назад +2

      Hey,
      Which workbook are you referring to?
      Glad you like the videos 😊

  • @mikrokosmos1652
    @mikrokosmos1652 2 года назад +2

    Your videos are so helpful for the IMAT too!
    After RNA polymerase joins the RNA bases with the complimentary DNA bases and pre-mRNA is created, what happens to the DNA strand that you took the bases from? Does it remain baseless? Or do the bases 'grow back'?
    Also since tRNA already has an amino acid attached to it, does this mean protein synthesis only refers to putting amino acids in the correct sequence to form a particular polypeptide?
    I used to think protein synthesis was the process of making an amino acid so I was a little confused.
    I'd be really grateful if you could clear this up for me since I have no base in biology.

    • @adailyfact
      @adailyfact Год назад

      Good luck with the IMAT, hope you got into medical school!

  • @ImranAwan-n9s
    @ImranAwan-n9s 8 месяцев назад

    In the Spec (3.4.3) for AQA, it states 'Gene mutations involve a change in the base sequence of chromosomes. They can arise spontaneously during DNA replication and include base deletion and base substitution. Due to the degenerate nature of the genetic code, not all base substitutions cause a change in the sequence of encoded amino acids. Mutagenic agents can increase the rate of gene mutation.' Are we just supposed to know that this can happen, or the detail of what the substitutions and deletions do? Also, is there a video covering this?

  • @javishulo3905
    @javishulo3905 3 года назад

    THANK YOU!!!!! SO HELPFUL

  • @ibrahimmiah562
    @ibrahimmiah562 3 года назад +3

    Is it not the enzyme rna polymerase which unwinds the helix?

    • @MissEstruchBiology
      @MissEstruchBiology  3 года назад +4

      no, but the cgp textbook says that in error. Any enzyme that is a polymerase makes a polymer

    • @ibrahimmiah562
      @ibrahimmiah562 3 года назад +2

      @@MissEstruchBiology oh ok thank you!

    • @aleezaahmed3947
      @aleezaahmed3947 3 года назад +1

      i think gyrase enzyme is what unwinds the helix

  • @paprikaroblox
    @paprikaroblox 19 дней назад

    Can this work for edexcel b exam board too?

  • @claudiaperretta6249
    @claudiaperretta6249 2 года назад +3

    Hey, thanks for the vid! Is this still ok to revise from for the OCR exam board? Thank you!

  • @zariyahsaoirse5952
    @zariyahsaoirse5952 3 года назад +1

    Isn’t DNA gyrase the one responsible for the unwinding of the DNA double helix, miss?

    • @MissEstruchBiology
      @MissEstruchBiology  3 года назад

      in reality there is more than one. For AQA, DNA helicase is all that students need.

    • @zariyahsaoirse5952
      @zariyahsaoirse5952 3 года назад

      @@MissEstruchBiology I see, thanks miss!

  • @whomerdoodles
    @whomerdoodles 3 года назад +2

    Helpful video series! But doesn't rer do protein folding or do the Golgi and rear both do it?

    • @MissEstruchBiology
      @MissEstruchBiology  3 года назад +1

      Hello,
      The main function of RER is to synthesise proteins as they have ribosomes. These proteins are then sent to the golgi to be processed and packaged.
      Hope that helps.

    • @whomerdoodles
      @whomerdoodles 3 года назад

      @@MissEstruchBiology sorry, so rer does not do protein folding?

  • @dannycartwright579
    @dannycartwright579 Год назад

    Thank you

  • @jencyauriavales4278
    @jencyauriavales4278 2 года назад +3

    Hi, as your an experienced biology teacher, I wanted some advice..... I'm half way into yr 12 and I haven't made proper notes and have not consolidated content we have been taught. I have realised my mistake but I am wondering whether its too late to start as I know I want to do really well but I have also wasted half a year.
    Thank you so much

    • @freyaskuse6476
      @freyaskuse6476 2 года назад +2

      Hi! I'm probably not the person you're hoping an answer from, but if you search up 'Biology with Olivia' on a website called TES, she has condensed notes available for free for the whole of year 12! I have made my own notes as well, but they should be useful to you as it would be difficult to make notes alongside learning the rest of year 12 content. I hope it helps :)

    • @MissEstruchBiology
      @MissEstruchBiology  2 года назад +5

      Hey,
      Definitely not too late.
      If you are after notes, I have the full AQA A level notes available here.
      missestruch.co.uk/product/a-level-aqa-biology-notes-full-set-topics-1-8-copy/
      These include all the theory for Y12 and Y13, highlight keywords and essay links for all topics. With these you won't need to make any extra notes, so instead you can focus on active revision strategies.
      Hope that helps 😁

    • @jencyauriavales4278
      @jencyauriavales4278 2 года назад +1

      @@freyaskuse6476 heyyy!!!! Thank you sooo much...... you didn't even have to help me but you did which was very kind of you! I looked it up and now only topic 1 is free and I have to pay for 2,3 and 4 but nonetheless those topic 1 noted will be very helpful..... I was thinking the same thing on how I will manage to learn new content while making notes for old content. Are you doing biology a level at the moment or have you already finished?
      Thank you so much once again

    • @user.004
      @user.004 2 года назад +4

      @@jencyauriavales4278 Hey I have her topics 1-4 notes, if you'd still like them? i can only send them as an email attachment though

    • @user.004
      @user.004 2 года назад +1

      @@jencyauriavales4278 Hi, I can send them now if you'd like? And no problem x

  • @icysid7855
    @icysid7855 6 месяцев назад

    this is RAD dawg yhhhh

  • @destined0645
    @destined0645 Год назад

    Please answer, some source state that it is RNA polymerase that does both unwinding and synthesis of the strand in transcription. But for DNA replication it is DNaA helicase . So it is RNA POLYMERASE that unwinds or helicase in transcription ?

    • @yoirfhmumfthtf
      @yoirfhmumfthtf Год назад

      DNA helicase unzips the DNA strand during DNA replication and it starts from the first hydrogen bond and travels to the end. But because the helicase enzyme can't 'see' where the specific genes it needs to unzip start(in transcription), RNA polymerase has to unzip the small sections of DNA instead as it knows where genes start and end. This is what my Biology teacher told me but it's better to just go with whatever your textbook says.

  • @DogeDogeriffic
    @DogeDogeriffic 2 года назад +7

    Hello, I’m currently really tempted to buy your A-Level biology notes for topics 1-8 but it’s a tad bit pricey is it possible to get the 25% bursary discount despite not being on bursary?

  • @esmmm990
    @esmmm990 2 года назад

    7:02 do we need to know the name of the enzyme for aqa

  • @tomrackham693
    @tomrackham693 3 года назад +3

    HERO

  • @alevelphysics6606
    @alevelphysics6606 3 года назад +2

    ❤️

  • @shahzarbukhlaw5963
    @shahzarbukhlaw5963 Год назад

    I’m confused is it DNA helicase or RNA polymerase to break the hydrogen bonds at 3:35

    • @MissEstruchBiology
      @MissEstruchBiology  Год назад

      DNA helicase breaks the H bonds

    • @lilyberchem
      @lilyberchem Год назад +1

      Yeah DNA helices breaks the bonds, RNA polymerase makes the phosphodiester bonds -- I believe

  • @aaronrajimon312
    @aaronrajimon312 3 года назад

    Hello, could we say free RNA nuclotides complantery pair with exposed base pairs or are we suppose to say free MRNA nuclotides???

    • @MissEstruchBiology
      @MissEstruchBiology  3 года назад

      hello,
      RNA nucleotides should be sufficient as long as you refer to the fact it is forming mRNA somewhere in your answer.

    • @aaronrajimon312
      @aaronrajimon312 3 года назад +1

      @@MissEstruchBiology thank you

  • @ak-7865
    @ak-7865 2 года назад +1

    2 amino acids delivered by tRNA ????? Isn't it one

    • @ak-7865
      @ak-7865 2 года назад +1

      Also if u don't mind me asking aren't u meant to mention phosphodiester bonds forming in transcription pls respond😀

    • @MissEstruchBiology
      @MissEstruchBiology  2 года назад

      hello, two amino acids are delivered at a time by two different tRNA molecules.

    • @MissEstruchBiology
      @MissEstruchBiology  2 года назад

      depends of the exam board. RNA polymerase joins adjacent RNA nucleotides together is the key marking point for AQA, but yes that is by phosphodiester bonds

  • @massacres2118
    @massacres2118 3 года назад

    Legend you

  • @jkjfk9225
    @jkjfk9225 2 года назад

    bro stop