Sara Manning Peskin on the Deepest Mysteries of our Brains | Closer To Truth Chats

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  • Опубликовано: 29 июн 2023
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    Neurologist Sara Manning Peskin discusses her book, A Molecule Away From Madness: Tales of the Hijacked Brain, about how the very molecules that allow us to exist can also sabotage our minds. Dr. Peskin recounts gripping tales of unruly molecules and the diseases that form in their wake.
    Purchase Dr. Peskin's book here: bookshop.org/a/86576/97813240...
    A college student cannot remember if she has eaten breakfast; by dinner, she is strapped to a hospital bed, convinced she is battling zombies. A man planning to propose marriage instead becomes violently enraged, gripped by body spasms so severe that he nearly bites off his own tongue. One after another, poor farmers in South Carolina drop dead from a mysterious epidemic of dementia. From to Alzheimer's Disease to hallucinations, A Molecule Away from Madness is an unputdownable journey into the deepest mysteries of our brains.
    Free access to Closer To Truth's library of 5,000 videos: bit.ly/376lkKN
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    Sara Manning Peskin, MD, MS, is an assistant professor of clinical neurology at the University of Pennsylvania. She attended medical school and received a master’s degree in cellular and molecular biology at UPenn, where she also completed her neurology residency and a fellowship in cognitive and behavioral neurology.
    Closer To Truth, hosted by Robert Lawrence Kuhn and directed by Peter Getzels, presents the world’s greatest thinkers exploring humanity’s deepest questions. Discover fundamental issues of existence. Engage new and diverse ways of thinking. Appreciate intense debates. Share your own opinions. Seek your own answers.

Комментарии • 44

  • @Bill..N
    @Bill..N Год назад +20

    Robert is one of the most accomplished interviewers who nearly always asks the right questions..

    • @diamonx.661
      @diamonx.661 Год назад +1

      He would truly excel at asking these deep and profound questions out of advanced AI models like GPT-4 and beyond.

  • @Wtvldoc
    @Wtvldoc 10 месяцев назад

    I have enjoyed Closure To Truth for some years now. I am 93 years old (Shortly be 94) retired as physician 17 years ago after practicing medicine for 46 years . As we age we have problems with Memory and Mobility. Every year I update Health Initiative Document to my children and grand children stressing how to tackle these problems. I have always maintained that Learning is the very Essence of life. I have 6 children, 10 grandchildren and expecting 6th great grandchild. Its fun playing Wordle with children and grandchildren every morning. My interests are Oil painting, music, sciences, astronomy and nothing better that RUclips to learn these every morning! I try to learn different disciplines!

  • @silvomuller595
    @silvomuller595 Год назад +7

    I'm an immunologist and I try to switch to neuroscience, because this is the closest I can get to doing reseach on consciousness. Thanks for the interview, it really helped me a lot. I'll get the book for my 32th birthday🎉

    • @CloserToTruthTV
      @CloserToTruthTV  Год назад +2

      We hope you enjoy the book-and happy birthday 💫

    • @njeyasreedharan
      @njeyasreedharan Год назад +1

      Close to consciousness but not close enough. Try philosophy of consciousness.

    • @silvomuller595
      @silvomuller595 Год назад +1

      ​@@njeyasreedharanYes, you may be right. I may not become a professional philosopher, but I know I must not neglegt philosophy.

    • @REDPUMPERNICKEL
      @REDPUMPERNICKEL Год назад +1

      No matter how rigorously scientific
      any investigation into the nature of the substrate of a sentence might be
      (whether the substrate be ink on paper or light from pixels)
      the meaning of a sentence will not be found in that direction.
      Now, since a 'written' sentence is simply a frozen thought
      there's bound to be an extremely significant connection between
      the meaning of a sentence and the meaning of the neural behavior
      that was responsible for its writing.
      Sentences are thoughts alphabetically encoded.
      Easy to imagine then that
      thoughts may be encoded by neural discharge frequency.
      That 'frequency' and 'code' are abstract notions might be a clue
      that leads to an understanding of just why
      thoughts and minds have their odd immaterial flavour.

  • @longcastle4863
    @longcastle4863 Год назад +7

    This was an excellent interview. Seems like the field is bounding forward. Thank you.

  • @owennovenski4794
    @owennovenski4794 Год назад +4

    Lovely interview. Respectful, honest, compelling topic leading to a genuine desire to inform. Very much appreciated. Thank you.

  • @aaronhow2568
    @aaronhow2568 Год назад +2

    Very neat interview right here! :) Thank you very much to both of you and any other people involved, for the upload! :)

  • @jaelhector
    @jaelhector Год назад +1

    "If people were more aware and came to the conclusion that even their own brain lies, the world could be a better place." Sincerely, Hector

  • @gsilcoful
    @gsilcoful Год назад +1

    Wonderful presentation.

  • @joegibbskins
    @joegibbskins Год назад +2

    It’s crazy that consciousness is so mysterious to neuroscientists when they can read the comment section on this video and see a hundred people who’s re absolutely certain of what causes it

  • @gsilcoful
    @gsilcoful Год назад +1

    Thanks!

  • @igor.t8086
    @igor.t8086 Год назад

    First, Robert, those two instances of inexplicable lucidity in verbal expression in the case of your late mother (who suffered from dementia late in her life) are amazing phenomenon! Really amazing! I’m convinced these extraordinary instances of peculiarities of consciousness speak volumes of its true nature. (I’m still 100% dualist and on top of that believe there may be some fundamental truth to my idea of *information++* that is based in mathematical logic). TBD.
    Second, the fact that we, as a species, are still here and have achieved this much as a civilization (building cities and organizing transportation; learning how to speak - properly, and writing the fiction & nonfiction, poetry, scientific papers, differential equations and dictionaries with 300,000 sharp definitions of words and notions and concepts; understanding the anatomy and diseases; creating & discussing arts, philosophy, diplomacy and ethics; all the while being resilient to pests, plagues, wars, famine and viruses - those on the brink of animate-inanimate matter, of digital nature and those of faux, deadly ideas; succeeding as teams of experts - scientists, technicians and engineers - to safely send selected few - astronauts - off this earthly cradle of divine, capturing, bounding gravitation - to the Moon and beyond; composing & conducting symphonies and enjoying dancing to the familiar, popular tunes; playing sports but while respecting rules; so civilized, on occasions). Truly amazing (if you put on a pink binoculars). Although, I think we should be concerned, too, because the progress, especially in cultural emancipation, is not a monotonic function… But, let’s worry tomorrow…
    Third, I think music may also prove to be the key to unlocking or initiating the natural cognitive potential & development in H. sapiens. (Ping-pong, too - at least for locomotor intelligence…)
    Related to the talk:
    *Haunted by a Gene* - Published March 10, 2020 - [The New York Times]
    www.nytimes.com/2020/03/10/health/huntingtons-disease-wexler.html
    _Dr. Nancy Wexler spent the last 40 years researching Huntington’s disease, a gradually debilitating hereditary disease, venturing to remote parts of Venezuela to study large extended families with high rates of the disease._
    *As Cases Soar, ‘Dementia Villages’ Look Like the Future of Home Care* - July 3, 2023 - [The New York Times]
    www.nytimes.com/2023/07/03/realestate/dementia-villages-senior-living.html
    _A new generation of treatment facilities is aiming to integrate dementia patients with the communities around them, blurring lines between home and hospital._
    *2 Leading Theories of Consciousness Square Off* - July 1, 2023 - [The New York Times]
    www.nytimes.com/2023/07/01/science/consciousness-theories.html
    _Scientists (Chalmers and Koch) revealed the results of experiments testing how our brains give rise to conscious thought - and ended a 25-year-old bet._
    *We Have a Dopamine Problem* - June 30, 2023 - [The New York Times]
    www.nytimes.com/2023/06/30/well/mind/dopamine-brain-behavior.html
    _The neurochemical has become a boogeyman for people worried about addiction and indulgence. But the real story is a lot more complex._
    *Science: Cannibalism, or ‘Clickbait’?* - July 1, 2023 - [The New York Times]
    www.nytimes.com/2023/07/01/science/archaeology-hominids-cannibalism.html
    _A recent study offered the “oldest decisive evidence” that our ancient hominid ancestors ate one another. But the field has a long history of overstating such claims, other paleoanthropologists note._

    • @GigiAzmy
      @GigiAzmy 10 месяцев назад

      what does it mean to be a dualist? First time I ever heard of that term. Is that like a materialist?

  • @ElkoJohn
    @ElkoJohn Год назад +1

    good show

  • @healthdecodedwithaltaf3647
    @healthdecodedwithaltaf3647 Год назад +1

    With respect no mention of the approximately 5lbs of bacteria in your gut with proven continued communication with the brain, releasing hormones vitamins etc. Correcting your microbiome should be a serious option ✨

  • @snarkyboojum
    @snarkyboojum Год назад +1

    TL;DR -> Sarah Manning-Peskin's book, A Molecule Away from Madness, explores the idea of brains being taken over by single molecules and the patient experiences and scientific discoveries that accompany such diseases. She discusses how these rare conditions can provide a groundwork for curing more common diseases such as Alzheimer's and Parkinson's. Her book also gives recognition to the unrecognized scientists who made discoveries in order to solve medical mysteries. It also looks at the physical properties of consciousness, and how science may never be able to understand the essence of consciousness.

  • @lifemantra0002
    @lifemantra0002 Год назад +1

    Waiting⏳

  • @babyl-on9761
    @babyl-on9761 Год назад

    Heard this interview and got the book immediately. Started reading the introduction and holy cow I can't understand what she is saying. She says that neurons don't appear i the human body below the eyes or at least seems to assume this. The then goes on to equate human life and couscous activity to that of inert machines. This can only lead to mind body even brain body duality with which I do not find a compelling argument. In human embryo development neurons are formed early on and through the development process all over the body and form the foundation on which the brain stands, they are inseparable.
    Would love to have a discussion on these issues, I can stand to learn more. I'll of course finish reading the book and make an effort to grasp her understanding.

  • @Dion_Mustard
    @Dion_Mustard Год назад

    She's completely off the radar. From someone who has had personal experience of Non-Local Consciousness, I can tell you now that the brain does not construct consciousness. It mainly harbours it, and coincides with it, but does not generate it. My consciousness, through out of body states, has expanded and extended beyond my physical brain. Only those who have had a similar experience can understand.

  • @bretnetherton9273
    @bretnetherton9273 Год назад

    Awareness is known by awareness alone.

  • @playpaltalk
    @playpaltalk Год назад

    Life is a box full of unexpected surprises good and not so good. I trained my small mind to blame Satan for everything that is bad and give God the credit for everything that is good.

  • @dipankarmallick5543
    @dipankarmallick5543 Год назад

    molecules responsible in...neurons neural responsiveness ain't it itself with...it ain't acausal it itself like liver...one needs be into performance performative with...as you in as you have it...much of grasp of it...yes there the innate exists...but to...to be towards is matter of...

  • @abdelchemami6964
    @abdelchemami6964 Год назад

    The promo code please for IAI subscription.

    • @CloserToTruthTV
      @CloserToTruthTV  Год назад

      Use code CLOSERJULY50 at checkout! Do you have the link?

    • @abdelchemami6964
      @abdelchemami6964 Год назад +1

      @CloserToTruthTV Many thanks Dear, I already subscribed without the code. Thanks again very grateful.

  • @m.k.wallner3145
    @m.k.wallner3145 11 месяцев назад

    It appears we're on a countdown to a future where we might be able to replicate our brains. It could happen in a couple of decades or a few centuries, but the rapid advancements in quantum computing and artificial intelligence make this a plausible prediction. The moment we can transfer our consciousness into a durable, artificial body and brain, we've essentially achieved immortality.
    Regrettably, the reality for most of us currently is far from this potential, constrained by the limitations of our natural biology. However, the inevitability of immortality looms, unless we find a way to self-destruct before reaching this milestone.
    With the prevailing mindset of the masses today, self-destruction isn't entirely off the table. There's a risk that we could annihilate ourselves before realizing our full potential for eternal life, which would be an irreversible loss of an extraordinary opportunity.

  • @Resmith18SR
    @Resmith18SR 11 месяцев назад

    That woman with the melanoma skin cancer wasn't grateful the doctor removed it because she got the bill.

  • @dthom71
    @dthom71 Год назад

    Didn't recognize this lady was a physician and neurologist until i looked her up. Was a little confused by her being described as a cognitive neuroscientist. She doesn't have a background in neuroscience even, at least from what i could find from a five minute search.

  • @somethingmorespecific6790
    @somethingmorespecific6790 11 месяцев назад

    Her voice.......

  • @anwiycti1585
    @anwiycti1585 Год назад

    Inaccessible : D

  • @soniahazy4880
    @soniahazy4880 Год назад

    ⛲️💎🪷🫧🎨🌈🦋🙏✨🧩

  • @jannaswanson271
    @jannaswanson271 Год назад

    The fear of the Lord is the beginning of wisdom. Man's highest thoughts are foolishness to God.

  • @dipankarmallick5543
    @dipankarmallick5543 Год назад

    who control the molecules inside of...& who hijack it...aryans😂