Sir, you did a really good job in this video. It's been a year since i started learning bioinformatics but I was never sure of what was going on until I came across this video. I decided to comment before even finishing the video because I already got 90 percent of the concept. Thanks a lot.
Thank you so much! I'm reading a publication about MSA and your videos helped me understand sequence alignment! Very wonderful explanations - by far the best video about sequence alignment on RUclips.
How is this calculated in bayesian terms? What are the assumed priors? This must be an infuriating probabilistic problem, if we can't even assume the distribution of mutation frequency?
You explain it so well! But i wanna know if there is any reliable software recommend for sequence alignment since i found so many different software online
Why you not used word from the sentence I think it's better until we get the idea clearly I feel like dizzy from these alphabet. Please keep it like examples words am really need that way to understanding Tq so much
Glad that you like the explanation. I don't have an implementation in Python. I did ask students who took my course to implement the algorithm, and they have done it using different programming languages.
didnt understand the 2nd rule can anyone explain plz or does it mean that at a single position in both the resultant sequences must not have a gap ATT-GC SOMETHING LIKE THIS? GCT-AC
You explained more in 11 minutes than my professor in 4 weeks, thank you
Thanks for watching!
@@KevinBioinformatics Your lectures are awesome, If any post doc position in your lab let me know
Sir, you did a really good job in this video. It's been a year since i started learning bioinformatics but I was never sure of what was going on until I came across this video. I decided to comment before even finishing the video because I already got 90 percent of the concept. Thanks a lot.
That's great. Hope you also like the other videos in this channel!
Honestly, this is the best and simplest explanation
Thanks for watching. Hope it was useful for you.
Thank you so much! I'm reading a publication about MSA and your videos helped me understand sequence alignment! Very wonderful explanations - by far the best video about sequence alignment on RUclips.
Thanks for watching!
great explanation !seriously i have my exam in few hours and you made it just so clear..thanks a miillion!!!
Thank you. Hope the video was useful for you.
Precise and well articulated. Perfect!
Thank you for watching!
Wow nice explanation 🙏
Hope it was useful for you!
Well presented .... So Smooth !
great and simple
Glad you liked it!
Thanks a lot for adding new videos, your videos are and very well explained.
Thanks. Hope you enjoy the videos!
This was very helpful. Subscribed!
I look forward to watching more videos.
Thank you so much.
Thanks for watching. Hope it was useful for you.
Well explained Sir.. Thanks for this video
Thank you for watching!
Wow!! My name is Kevin too. So happy to subscribe to your channel🤗🤗
I really need in depth knowledge in Bioinformatics for my masters thesis.
Hope the videos are useful for you! Comments are welcome.
thanks a lot. that was super helpful
Thank you so much!
Great explanation. Thank you
哇 講的真的好好
Thanks! Hope you enjoy the videos.
This is so great. THANK YOU
Amazing!
How is this calculated in bayesian terms? What are the assumed priors? This must be an infuriating probabilistic problem, if we can't even assume the distribution of mutation frequency?
really helpful and easy explanation. thanks :)
Thanks for watching. Hope it was useful for you.
You explain it so well! But i wanna know if there is any reliable software recommend for sequence alignment since i found so many different software online
This was super helpful!
Thanks for watching!
this is great! Thank you so much
Thanks for watching!
Why you not used word from the sentence I think it's better until we get the idea clearly I feel like dizzy from these alphabet. Please keep it like examples words am really need that way to understanding
Tq so much
gd bless. thank you!
graet
Why is it important to generate alignment sequences using protein sequences and not DNA sequences?
Usually there is a higher level of conservation at the protein level, and thus protein sequences can be better aligned than DNA sequences.
@@KevinBioinformatics thanks 😊. I have exams in two days and I really needed to understand that concept.
Very interesting explanation, Do you have the implementation in Python?
Glad that you like the explanation. I don't have an implementation in Python. I did ask students who took my course to implement the algorithm, and they have done it using different programming languages.
didnt understand the 2nd rule can anyone explain plz or does it mean that at a single position in both the resultant sequences must not have a gap ATT-GC
SOMETHING LIKE THIS?
GCT-AC
That's right!