Medical Minute Archive 05 20 2023 microRNA aging

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  • Опубликовано: 25 янв 2024
  • Medical Minute
    Aired on Georgia Public Broadcasting on May 20, 2023
    Dr. Joseph Hobbs, Chair Emeritus of the Department of Family and Community Medicine at the Medical College of Georgia at Augusta University, discusses a microRNA that one day could prevent some of the potentially debilitating hallmarks of aging.
    “We feel the effects of aging in sagging muscles and weaker bones. Now scientists have evidence that inhibiting a specific tiny RNA, called a microRNA, which helps regulate gene expression and consequently cell function, may help. Levels of microRNA-141-3p increase with age, and correlate with classic aging changes like weakening bone and muscle, as well as higher levels of destructive inflammation. When scientists used an inhibitor specifically designed to inhibit microRNA-141-3p in older mice, a more youthful profile of all these key indicators emerged. The scientists hope one day to prevent some of the potentially debilitating hallmarks of aging. One next step includes seeing how blocking the tiny RNA impacts other aging-related changes like dementia. I’m Dr. Joseph Hobbs.”
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