Berberine shrinks Arterial Plaque, Study Shows
HTML-код
- Опубликовано: 26 ноя 2023
- JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]
Join the Physionic Insiders [Standard Tier]: bit.ly/PhysionicInsiders2
Join the Physionic Insiders [Pro Tier]: bit.ly/PhysionicInsidersPro
Standard Tier: Access to the Premium Video Library, Full Study Analyses (+ Summaries), Insider Podcast, , Research Reviews, and More
Pro Tier: All benefits of the Standard Tier + Live Sessions with Me, Consulting Lite, and More
HEALTH AUTONOMY [COURSE]
Learn to Analyze & Apply Studies for Yourself: bit.ly/healthautonomy
JOIN THE COMMUNITY
Join my Community [It’s Free!]: bit.ly/PhysionicCommunity2
EMAIL LIST
One Weekly Email of Value: bit.ly/2AXIzK6
HIRE ME FOR CONSULTING:
Consulting: bit.ly/3dmUl2H
DONATIONS FOR A SCIENCE BASED CAUSE
Patreon: bit.ly/PhysionicPatreon
OTHER SOCIAL MEDIA
Instagram: bit.ly/2OBFe7i
Created with Biorender
References (Copy & Paste into Search Engine)
[1] [Study 235] doi:10.1038/s41392-022-01027-6
[2] doi:10.2174/1871530320666200910105612
[3] doi:10.3390/ijms24031940
[4] doi:10.1016/j.phymed.2023.154716
*******CRITIQUES, RULES, AND NOTES*******
Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and RUclips is less likely to promote it (these videos cost me a lot of money to produce).
Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:
Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of RUclips comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, RUclips auto-deletes links, so I do not see most comments with links attached.
RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.
If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).
Please use the following link to submit your critique: bit.ly/PhysionicCritique
Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.
#berberine #heartdisease #reversingheartdisease
Two years ago, a 2D echocardiogram revealed coronary calcification, which was preventing one heart valve from closing. My doctor indicated that no surgery was immediately warranted, and the issue would be monitored. I sought some way to address the calcification, and eventually learned about Berberine possibly being able to dissolve the calcification.
I started taking Berberine as a daily supplement about a year ago.
Last month, a follow up ultrasound of my heart found all valves to be functioning normally, and there were no signs of coronary calcification! I am so relieved and glad that it worked. Meanwhile, my cardiologist asked for the second time, "What's Berberine?"
Go figure.
Congratulations :)
I mean, what what, if berberine dissolves calcification, that is bad, very very bad. Heart attack or most likely stroke waiting to happen.
@@nebojsa1976
Use more words. What do you mean.
@@d_e_a_n You have 2 layers. One is soft (soft plague) and one is hard (calcium). If you take away hard one with berberine, soft one will come out and cause stroke. Couldn't be simpler.
@@nebojsa1976I'm not sure it works like that.
Just to be safe, I'm taking some chocolate cake along with my berberine.
Me too, I love my bourbon.
Try making brownies with urfa biber peppers
It’s easy to see the correlation. Berberine lowers glucose and insulin, high blood glucose increases inflammation in arteries which causes plaque.
My dad took both Metformin and Berberine. Metformin affected his kidneys negatively and his blood markers for cholesterol and liver were not great . With Berberine his cholesterol levels went down and his liver markers improved and his kidneys too
Dihydroberberine is better
I avoid mRNA vaccine
As a hamster, I feel really left out for no reason! 🐹
That’s because u identify as pondboy, not as hamsterboy
@@itsshepherd5618 I didn't realize that putting your species in your username was required! Are you a German shepherd, then? Prounoun it, and distinguished from at least 5617 others by your number? 🐹
@@pondboy3682 lulz
me too
Politicians are squirrel hybrids, but they just don't play in the road enough.
My A1C was 6.8 / 8 months ago. I looked for ways other than low carb /exercise which I have been doing already for years to try and help lower my A1C. Came across some good info on Berberine. So immediately found a respected brand and began taking 500 mg a day. After 8 months and no change in diet/exercise from normal routine my A1C came back at 5.1 on Friday. I was pretty hyped about that. Having any cardiovascular benefits on top would be a bonus.
A1C levels can fluctuate because of vitamin deficiencies, supplements, stress, lack of sleep, and more.
what's the name of the brand?
congratulations...sound like you are on your way to better health!
What do you think is "low carb"? Maybe not low enough, or not complex enough. Not all carbs are the same. Clearly sugar calorie for calorie has a significantly damgaing effect on your A1c, more than the same amount of jumbo oats.
@@chazwyman My low carb lifestyle is basically under 30 net grams of carbs a day with an average of 10-15g of sugar per day 6 days a week. Sugar source would primarily be from Greek yogurt and natural peanut butter. I pretty much eat the same things everyday. And I tracked it for a month to get the average. 1 day a week I have my cheat day which might be pasta/sandwich/pizza/tacos/french toast…etc. Not an all day cheat day. Just one meal. And of course you have to live a little. Oh and I also fast a minimum 12 hours per day. Originally I thought my original results of 6.8 were the result of faulty testing, I couldn’t believe my A1C was that high. I told my Dr the next step would be ZERO carbs. What is strange is my blood sugar was 80 with an A1C of 6.8.
My opinions are as follows... Bernerine is usually taken twice a day before meals, similar to Metformin, at doses of 400 to 500 mg. Prohealth Longevity and Swanson sell it online. Swanson berberine is about half the price of Pro-health Longevity berberine. Bernerine has a very distinctive taste, and it tastes incredibly bad so you want to get it in capsules. Consumer Labs tests a lot of supplements and Swanson is often highly rated. For some reason they don't test Prohealth Longevity as of yet.
Been subscribed for 7 years or so. You're getting a lot more deserved views. Congrats!
Great video as always! Love the editing as well. Good job!
What was the dose of berberine taken in the study. Kind of an important piece of information.
Very informative, concise and helpful! I appreciate your style, thank you!
You are awesome with your communication of medical data. Enjoy listening to your presentation. Thank you!
Although French lillies sound like a great medicinal source, it's my understanding that recent studies found that metformin exacerbates neuropathy, and this effect is multiplied further by gabapentin.
My first exposure to gabapentin was due to a bout with shingles that I had in December 2015. One year later, I was diagnosed with high blood pressure. The medicine I was prescribed for high blood pressure was subsequently found to cause coronary calcification. So for my shingles I was given gabapentin, which likely caused neuropathy and inflammation, which caused high blood pressure. The blood pressure medication caused calcification in my circulatory system, which likely triggered my type 2 diabetes. I was prescribed a. Increasing amount of metformin for the diabetes. Within a year of metformin exposure, I began having neuropathy in my feet. I was prescribed an increasing amount of gabapentin to deal with the neuropathy. It took less than six months of metformin and gabapentin to lose nerve sensitivity in my feet. Along with the lost nerve sensations in my feet, I also began developing skin ulcers on my ankle that don't heal. For example, in the last week of December 2021, an ulcer wound formed on my right ankle, which persisted until the second week of October 2022. I was taking metformin and gabapentin during that time.
The wound care doctor that was treating the wound got upset with me because the wound was not healing. He told me that he was going to have me fitted for a prosthetic foot because amputation was warranted if the wound continued in its static state of being. His point was valid, because I could have contracted gangrene at any time. Faced with the prognosis of an impending amputation, I decided to research antiseptics. More specifically, I was interested in what antiseptics would be used in the context of an amputation procedure. To my surprise, the answer was Acetone.
My ankle got to the point where the agony was all consuming. I had a can of Acetone, and a machete. I had to do something. The machete was out of the question. There's just no way I would give up my foot unless it definitely had gangrene. So that left me with the Acetone. I soaked a cotton cloth with Acetone and applied it all around the wound. It hurt pretty bad, but not more than the wound. So I decided I needed to drown the wound in Acetone. I filled the wound, and experienced a burning sensation that almost rendered me unconcious. The burning actually went away pretty quick. I filled the wound again, and kept adding drops of acetone as it evaporated and absorbed. Within a minute, some bubbles came up from the bottom of the wound. I applied pressure, put bandages on, and within ten days, the wound was completely healed. Since then, any time I have a mosquito bite, or any skin abrasion, I soak a cotton ball with acetone, hold it on the wound or bite, and by the next day the wound or bite will have completely healed. I am not a doctor, so please dont take my personal testimony as medical advice. The issue relates to all of these secrets that the medical industry holds as a matter of protecting their income. Acetone should be the go to antiseptic solution in our drug stores. We shouldn't be going to the paint section of a home improvement store to get the best antiseptic for treating minor skin wounds. Acetone has a danger aspect I hadn't known until I was researching it. Acetone is the most addictive liquid to drink in the world. It took desperation for me to pour acetone on a wound, but I still have my right foot. I don't know what possesses one to drink Acetone, but apparently just one taste of it results in a fatal addiction lasting less than three months.
It wasn't until this year that i was finally allowed to stop metformin, as Gardiance was available as a generic, so it was covered by insurance. I had quite the gabapentin in 2021. It was also in 2021 that the coronary calcification was found to be preventing a valve in the left atrium from closing. The condition was an inoperable time bomb. That's when I researched ways to treat coronary calcification and found out about Berberine through the video this thread links to. My heart was checked via uktrasound in August of this year. There were no signs of any coronary calcification.
I have been off of metformin for four months now. Very slowly, I am noticing a return of sensation to the skin on my feet. I also notice that neuropathy ebbs and flows with sugar levels. No spikes in sugar , no spikes in pain. The spikes can go in either direction to the same effect. Therefore the focus is on learning where the balance is for our bodies, and helping our body maintain that balance. Part of doing that is not having to chronically take medications like metformin, gabapentin, and hypertension medications which may make some numbers on a report look better, but ultimately prove to be cures that create more disease. It's all about making money to feed the illustrious hospital profit machine. For those who just became unglued from what I wrote in that last sentence, I never signed an NDA. The truth is the truth, and our medical industry needs to stop their practice of keeping secrets as a means of protecting revenue. Cancer was cured in 2016. Yet last year my sister was diagnosed with breast cancer, and received traditional surgery and chemotherapy. In the same month she was diagnosed, I had a routine physical which found at least 13 skin cancer lesions spanning from the top of my head to my lower extremeties. I treated myself for the skin cancer by taking a course of Fenbendazol, one pill per day for four days, three days no pill, repeat for 90 days. The skin cancer diagnosis was made in October 2022. My first appointment with a skin cancer specialist was in the last week of January 2023. The shock and disbelief on the face of the specialist was priceless, as every lesion had been photographically documented, and none of the lesions were found active. Instead, I have white spots now where the cancer had started.
My sister refused to even consider the treatment I took because she trusted her doctor. She didn't lose her spouse to cancer. I did. Because she didn't, and still won't avail herself of the cure (because Im the little brother, so what do I know,.right). Sadly this means that at some point the cancer she had will metastasize, or the chemo they administered to her will cause a new form of treatment resistant cancer. She's essentially on an assembly line for the medical industry's income, when she could have taken the course of Fenben for less than $100, and she would be cancer free.
I do apologize for going on such a long tangent here, which really wasnt warranted by the simple question. But I saw the word metformin, and that got me going to where I had to spill these beans.
There's so much to say about all of this, I am planning to start a youtube channel to help spread the word and hopefully make a difference in this world for all the people that are needlessly suffering, simply because they trust their doctor to do what's best for them. The doctors do what is best for their practice, so they can support themselves. Patients are just the inventory doctors use to make their money. It's really that simple. I believe that there is always a need for doctors, even if a lot of their hidden tricks of the trade are common knowledge, doctors will always have plenty of work, and they deserve a handsome reward for the differences they do make in many lives. But please, stop taking metformin and insist on a replacement med like gardiance.
Cheers
Metfotmin blocks B12 absorption. If you get peripheral neuropathy GET A B12 LEVEL (even better, an RBC B12 level. ) If 800.
God bless you for sharing your experience. I pray you are well. You are brave not foolish. It's so difficult to separate truth from lies these days. Sometimes the stress of trying to do that is more detrimental to our health than anything else.
Is this the power of AI ?
O just finished reading your story, and I have to add that I have a very similar story! Foot infections, neuropathy, type2 diabetes, gabapentin, metformin, etc, etc. I suffered with what was diagnosed as neuropathy, years before becoming TYPE2 diabetic, and every doctor blamed it on sugar. I always knew they were wrong but it took more about 15 years of looking for answers to realize that I wasn't wrong. The prescription medication I was continually being prescribed caused so much damage and pain to my body, but starting in September 2019, after 3 months of researching veganism and going vegan for 2 years, I was able to get off of all of the 16 pills per day I was taking, plus the pain meds. None of my doctors seemed to be happy with me getting healthy, except for 1. I do a vegan diet 4 - 5 days per week, and allow myself to eat meat the other days, and I feel great. I still have some tingling and numbness in my feet, but it's not bringing me to tears anymore and I Don need pain meds at all.
You're correct with all that you said above. Blessings to you! We have to wake people up! The food in America so many eat is making us sick, and the medication doesn't really heal anything, in the long term, especially.
Excellent video; love your humor! 💠
Thank you for posting this - fascinating and enlightening.
Awesome breakdown! Thanks
For type 2 diabetics , the use of berberine along with K2 +D3 supplements, healthy eating and exercise is very helpful at removing arterial plaque . Just make sure you don't go overboard on dosage and eat consistently healthy.
What would happen if you went overboard?
@@semiprolific774My dad took both Metformin and Berberine. Metformin affected his kidneys negatively and his blood markers for cholesterol and liver were not great . With Berberine his cholesterol levels went down and his liver markers improved and his kidneys too
@conscience-commenter Define "healthy eating." Everyone's idea of eating healthy is different.
Expand on the effects of “going overboard”. K2 (mk7) along with d3 aids in driving calcium from arteries into the bones.
How do you know all this? Are you an Oracle? Should I buy Anaconda Copper?
I’m so grateful that I found this channel
I love those diagrams! It's so much easier than reading words that describe those actions.
Love Berberine and Myo and D-Chiro Inositol for metabolic balance!
Thank you.
Thanks for the info, but I truly love your sense of humor.
I am my own guinea pig. I didn't think I needed statins as the doctor did. I got a CAC scan (coronary artery calcium). My score was 107. For two years I took statins and then got another CAC scan. It had gone up to 193 even with 117 cholesterol. I stopped the statins and just kept with my 50 year vegetarian diet and added K2, D3, magnesium. In two years it went down to 164 even with cholesterol around 235. But the doctors wanted to see low cholesterol. I found that lecithin would reduce cholesterol. So I took it for two more years and my cholesterol was about 199. But the arterial plaque score went UP to 293! Why? Lecithin has choline which increases your TMAO. I'm one year beyond that into only K2, D3, magnesium. I'll see if it goes down again as it had before. Seems like when I personally lower cholesterol, the plaque in my arteries increases. (I have no physical symptoms of heart problems. I think people with 1,500 and 2,000 CAC scores are getting the bypass surgery.)
Great info as usual. Thanks a lot. It helps. You're good, man. ❤
💓 great information !
Highly interesting facts served with a dose of chuckles - thank you
Very intriguing indeed. Thanks for the cool TMAO info!
Thanks so much for your balanced information.
Allicin found in garlic also lowers TMAO.
Dihydroberberine is much better than berberine .
It's really cool that the youtube analytics show the percent of hamsters viewing along with all the other info.
I’ve always been impressed by it, too. 😛
LOL
😂
Amazing information and the video.
I take it for a while and I love it!
Thanks for your informative videos
How are professional researchers still not able to produce robust, high quality studies? Boggles my mind.
Funding
Exactly. The Big Money interests won’t support research that has the potential to reduce cash inflows into their coffers…..like BIG Pharma, BIG Agriculture, BIG Medicine, BIG Food, BIG Government, etc.
Do you see a trend there?
Since the top 1% of all income earners control 90% of stock market wealth in this country they have a major incentive to suppress and de-fund researchers who produce studies that would lead people to better health and less reliance on drugs, processed food, doctors, hospitals, etc.
The 1% don’t give a damn if the remaining 99% are sick and unhealthy and dying before their time. Killing us slowly is PROFITABLE for them.
I think you are missing a key factor..They can and are able to produce the most sophisticated research but that would greatly reduce their profits from all the drugs they push down on people. Big pharma is the second largest industry after the industrial-military complex, and we are talking of hundreds of billions of dollars.
Yes. It all depends on who’s paying for “research”.
Companies and the US government can not rape billions from natural compounds such as berberine and thus no monies for research.
Great stuff as always. I've been taking Berberine for about a year and it seems to help me keep my weight down and blood sugar in check. I've had some stents in the past so if this helps in that area all the better. I would think just keeping sugar in check and weight down helps with the heart in itself.
I too have had two stents put in, and I was on a statin for a year post implant. I started having adverse effects from the statin (diarrhea, a known side effect) so I decided to try Berberine. I told my doc what I was doing, and asked to monitor my blood work to see what the net effect was going to be on it. My cholesterol is lower on Berberine, and my APOA1 markers are better than they have been in years. And the diarrhea is gone. I see no down side to taking Berberine other than the price. Statins, covered by insurance only cost me $3 dollars a month. The Berberine is about $30 a month. WORTH IT!
how much you take a day and milligrams? thanks @@Nivloc317
@@Nivloc317My dad took both Metformin and Berberine. Metformin affected his kidneys negatively and his blood markers for cholesterol and liver were not great . With Berberine his cholesterol levels went down and his liver markers improved and his kidneys too
@@Nivloc317I’m glad to hear you’re doing well after your stents and that Berberine is improving your blood work! I recommend most of my cardiac patients also consider taking Magnesium Glycinate and vitamin D3 + K2 supplement as they will further reduce your risk of another cardiac event.
Research Barbara O’Neill she suggests 1/4 teaspoon of cayenne pepper daily to naturally thin the blood
Love the diagram?
This was interesting.
Thank you!
Leaf Blowers at 8am on a weekend morning = rage inducing 🤣
my friend is a landscaper he has an electric leaf blower, it is silent there is no excuse
Someday, almost everything will be electric. The world will then be quieter and people's blood pressure will be lower.
Great topic as usual. ☘️☘️☘️
Pretty fascinating.
Damn i love your humor man!
Great finding
Thank you sir. Could you mention other effects of Berberine more deeply...including dosage etc. Cheers
I’ve heard this once before and kinda blew it off but hearing again from you is shocking (in a good way).
Nice to know. I've already ben taking Berberine to help my arrhythmia (it's pretty effective)
Thank you for the video. Very informative
I started taking berberine…made me nauseous a couple of hours later, but nausea didn’t last more than 15 minutes or so. More concerning is that it made me feel very lightheaded & faint, & that didn’t last very long either. However, those side effects were uncomfortable enough that I quit taking it.
Best look into Nattokinase, Lumbrokinase and Serrapeptase if certain unmentionable health challenges have you in a fit.
What health challenges are "unmentionable"? Covid? If so, it's hardly "unmentionable".
@@incognitotorpedo42 I gave you a link at the NIH regarding Nattokinase and Cardiovascular health... it was immediately removed. You can find it with little effort. Oops, screen refresh and it's there.
I take all 3
Exercise, grounding, and avoiding sugar and excess carbs can prevent and even reduce plaque size. Its all about reducing and preventing inflammation
What is grounding?
@@xiamengbabyno footwear. Going barefoot while doing outdoor activities. Not on concrete, asphalt pavement. Soil and grass only
Does the study address whether this is impacting soft plaque, hard plaque, or both?
Can you do one on nattokinaise ? Also, does fasting shrink the plaque ?
Best supplements for blood clots, plaque buildup and remove calcium from the arteries and yes all true from CT scan, stress test, bloodwork and echocardiogram. Berberine, K2 & D3, nattokinase and kyolic garlic with lecithin
Dr. James Robert’s did three two hour lectures on RUclips just on Berberine and it’s effect on human systems.
Good stuff. Thank you. Like your sense of humor too. Much like mine.
Put the study up !!
It is!
I would love you to do a podcast about akg😊
3.2% is in some studies a margin of error. I'm not sold. If it helps other items such as A1C I'd stick to that vs. relying on it reacting to a biome component that could wildly vary in people.
Excellent 👍
Starting to like your content. Would you be able to give us your view on Alpha-GPC as GH booster ? previously I asked if you could also say your opinion on MK677
Question. I have read mix human studies where transplant patients have used berberine.
Can you do a video on transplant drugs berberine? From what i can tell berberine increases the strength of the meds.
I would be curious about the relative effects of Berberine versus Metformin since they are comparable in many ways. If there was some plaque removal effect of Metformin it is surprising that such studies have not been undertaken.
metformin is very affordable where i live in Asia and you can get it without prescription, no money in studying that, but that is me being skeptical of the pharmaceutical industry
@@marknasia5293 industry doesn't fund all the studies, there's also public funding and other sources as well. Govt should prioritize funding studies that the industry doesn't have an incentive to. Maybe they already do
Well given the amount of campaign donations from Pharma, don't expect government to be funding such studies anytime soon!!
There are animal studies and there was an observational study showing fewer vulnerable plaques in those receiving metformin. I scanned the papers quickly but there is data and I read your comment before watching this video.
@@snowbird6855 yeah, the world is not as simple or screwed up as you think. I'm currently working on a research project funded by the govt (not in the medical field), that's not at all in corporate interests, even though they make huge campaign donations too. And so are many other people I know.
Apparently resveratrol lowers TMAO after meals. So that might of interest too.
My understanding is as follows: It is mainly the soft plaque that may lead to a heart attack (when it erupts into the bloodstream causing a clot), the "hard" plaque which is illustrated in the diagram as plaque (I assume it are the calcium deposits in the artery that lightens up on the diagram and give an indication of the amount of hard plaque) is stable and does nearly not lead to a hart attack. Further my understanding is that statins have a mechanism to convert soft plaque into hard plaque. In other words, when using a statin the amount of (hard) plaque as measured via the calcium deposits may even increase and the amount of soft plaque will decrease, i.e. the risk of a heart attack will also decrease. So only measuring hard plaque does not tell us a lot about the risk of getting a heart attack...... Something to consider???
I'm certainly no doctor but from what I think I understand, the soft plaque eruption is a consequence of increased inflammation at the site. If this is so, then protocols for reducing inflammation are also something to consider. With this in mind, I've been taking serrapeptatse and nattokinase enzymes on an empty stomach first thing in the morning, waiting an hour and then eating as usual. Berberine seemed to be recommended immediately before, or midway through, a meal, and also many people recommended taking it with milk thistle, so that's how I take it: berbering & milk thistle, usually midway through my midday meal.
I have no data or scores to share, but in case you found any of this 'food for thought', I shared. Cheers!
I just recently survived a 100% blockage of the left ventricle, hard plaque causes the constriction in the artery, soft plaque dislodging log jams against the hard calcified plaque and you are suffering a heart attack. Neither plaque is good, and calcified plaque causes angina.
@@TheRoadhammer379 what do you think caused the buildup of the calcim in your arteries?
Not aware of any reputable study showing statins harden calcium. Sounds like big pharma marketing.
@@utubeape Inflammation
What were the amounts of Barberine used in the studies?
Interesting. But could the results be caused by the reduced blood glucose levels that Berberine causes?
Dr Been made a video about this earlier this year. It seemed like a small effect to me, but he thought that any reduction in plaque would be great for some people. I was taking Berberine for a while to lose weight, maybe will start again.
Which berberine product do you recommend?
Rather than taking Berberine, would it not be easier to reduce dietary choline to reduce TMAO in circulation?
I started taking berberine about a year ago to help improve blood sugar management and gut health and it has definitely helped with both. My A1C dropped from 5.8 to 5.5 and my gut is functioning much better. I've never had my arterial calcium score tested, but my vascular health (BP, lipid profile, etc) are excellent so I'm not too concerned about plaque. In any case, I do recommend 500mg berberine daily for prevention, but be sure to choose a reputable brand that is 3rd party lab tested for potency and purity.
@dlg5485 Thank you for your contribution; which brand did you use, please? Did you combine it with silymarine to improve berberine bioavailability?
@@user-fx5df1ur4mi shifted to liposomal berberine and it made a noticeable difference.
@@user-fx5df1ur4m How does silymarin improve the bioavailability of berberine? I'm not aware of a bioavailability problem with berberine.
@@user-fx5df1ur4m My preferred is Douglas Labs Berberine Balance, but it has been out of stock everywhere for several months and each time I ask them about it they say it'll be back soon. I switched to Thorne Berberine which is a fine product, but I prefer Douglas Labs. Hopefully it will be back in stock soon.
What brand you using?
Berberine always makes me think of Thundercats 😂
The “TMAO causes CVD” hypothesis needs to address the fact that fish consumption. (Which is VERY high in TMAO) is associated with lower risk of CVD
Depends on the fish that you are eating and where they are from.
You can't just look at all fish as "fish".
The further up the food chain the more compounds (mercury and other industrial pollutants) bioaccumulate.
Fish lower down in the food chain have less of the other garbage that you don't want in your diet that is in higher concentrations in fish like tuna, sword fish, etc.
Fish, wild not farmed, are also high in some healthy compounds. Cold water fish, for example, are high in healthy lipids (omega-3, etc). The lower down the food chain the more plants that the fish are eating rather than other fish so less you are getting your low in the food chain fish from polluted waters, they are not giving you as much of a dose of chemicals from industry and farming as higher level fish / predatory fish.
The lower on the food-chain fish might have enough omega-3s to offset some of the damage brought on by the TMAO.
"Fish" is a very broad term. It would be like saying food from fast food places is bad for you. Well, if you get a salad with the vinaigrette or baked potato from Wendy's or you build a salad bowl at Chipotle out of the veggie options and leave out the meat and cheese you can easily make for a much healthier meal than if you just averaged every meal combination together to figure out the health benefiting or detrimental impacts of "fast food". Just the beverage choice makes a huge difference. You getting soda? A 12 ounce soda or the 32 ounce soda? Maybe you get water or unsweetened tea.
@@mjs28s The assumption that TMAO is delivering damage, which you state, is perhaps an overstatement of some slivers of evidence.. for some. The other person was trying to say: on paper, in the way nutritional epidemiology assesses these broad dietary impacts, the pescatarians are the only people living longer, when compared to vegetarian and vegan or everybody else. As well, many fish contain high quantities of TMAO, much of which is delivered to the human eater almost directly. Meat eater is a broad term; Fish eater is a broad term; Vegetarian is a broad term. We'll have to imagine that Pescatarians are eating Fish of several shapes and sizes.
@@mjs28s The heavy metal content of fish has nothing to do with TMAO, unless you know differently………
Farmed fish is much lower in heavy metals than wild (not to mention parasites which is why you should never eat raw wild fish)..plus since they are fed a plant based diet, won't have the issues of cumulative toxins putting them down the food chain
Look at amla studies. Carotid imaging showed a small plaque. I started taking Amla in liquid form and the next year that plaque was gone.
Maybe the reduction in insulin resistance plays a part as well.
>>Multiple studies have demonstrated that insulin resistance is a strong predictor of atherosclerotic cardiovascular (CV) disease (ASCVD) (1-11) and have been summarized in a recent meta-analysis by Gast et al. (12).
Molly is a good source of reducing many illnesses. It makes me dance all night long, which is a very effective aerobic exercise. 😊
Oregon grape is a wonderful natural source of beberine
What's the +/- tolerance of machine reading these thicknesses?
Why would anyone expect plaque to decrease in size based on mechanism of decreased TMAO formation? Assuming TMAO is a oxidant from its description and oxidize LDL is the necessary initiator of plaque formation then expected result should be a decrease in plaque growth.
Dosages please?
If I currently supplement with magnesium and nattokinase, would it be safe for me to also take berberine? I am not on any medications. I am just concerned that all three of these supplements can thin blood.
What dosage of berberine did the study subjects receive?
Can you take it with metformin
What dosage did they take in this study?
Do you have any thoughts concerning glaucoma ?
Interested in knowing how the plaque buildup was lessened. Was it dissolved or dislodged?
dislodging would medically result in a stroke
I had a bad reaction to berberine, vomiting for 2 days, couldn’t keep food or water down. I’ve never spewed so much in my life.
Whey protein powders contain about 1% lecithin, which gets converted into choline, and subsequently TMAO. Does this mean that whey protein powders are a risk for atherosclerosis and CVD???
Any research on prolonged fasting and soft plaque and hard plaque?
How many mg berberine?
I take it, for blood sugar lowering. I had 8,5 a1C and now, for more than 4 months, 5,5 .....for heart, I take also krill oil, good quality fish oil, and garlic oil. I had no previous heart problems, but these measures (plus daily gym) ensurem my last cardio exams were 100% OK
@@mrcadoia 1500mg/day divided in 2 pills.
By the way: I started with 2 pills/day (each 500mg) of metformin. Three months after my 'food protocol' I had an appointment with my endocrinologist doctor, and the a1C was already 5,4 and she reduced the metformin to 1 pill/day. Four months later (now) my a1C is 5.5 (lower than the 'normal' limit = 5.7) so I hope she will eliminate the use of metformin, and make a new blood test in 3 months (my appointment is next Wednesday).
@@mrcadoia I take both. Metformin prescribed by the doctor, and berberine as a result of my research.
@@danieldmgMy dad took both Metformin and Berberine. Metformin affected his kidneys negatively and his blood markers for cholesterol and liver were not great . With Berberine his cholesterol levels went down and his liver markers improved and his kidneys too
So does Vitamin K2.
Is it worth switching to Dihydroberberine?
If we stack berberine, EVOO and others I wonder if the effects would be additive or synergistically multiplicative? One might find a combo that uses two or three ingredients that is really good for clearing plaque.
Maybe it's role is more preventative than restorative.
My LDL went up after a year on Berberine and it gave me anxiety and palpitations, it all went away when I stopped, I don’t have any side effects of Crestor
21 subjects is practically an anecdotal report, like almost every other "study" of berberine.
Are the Berberine benefits also available with Dihydroberberine? I am unable to take berberine due to gastrointestinal side effects, but have been taking Dihydroberberine for 3 years now.
Does metformin shrink plaque or does it prevent the formation of plaque?
So what is the dose ?
How do we know that the mechanism of action is definately with the interaction of gut microflora and not Berberine’s ability to reduce blood glucose levels?
Does dihydroberberine do this as well??
Well, did you know that niacin is a choline blocker (I can provide source(? Whar do you think is going on there?