The CRISPR Apostle: Rodolphe Barrangou
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- Опубликовано: 28 авг 2024
- www.iBiology.org
For millennia, humans have been harnessing #microbes to produce everything from breads, to cheeses, to alcohol. Now these tiny organisms have produced another powerful revolution - the gene editing tool CRISPR. Rodolphe Barrangou, Ph.D., was working at the food company Danisco, where he was trying to produce yogurt lines resistant to contamination. In a series of groundbreaking experiments, he helped uncover what CRISPR was, how it worked, and why it could be so transformative.
Speaker Biography:
Rodolphe Barrangou, Ph.D., studies beneficial microbes, focusing on the occurrence and diversity of lactic acid bacteria in fermented foods and as probiotics. Using functional genomics, he has focused on uncovering the genetic basis for health-promoting traits, including the ability to uptake and catabolize non-digestible carbohydrates. He spent 9 years at Danisco-DuPont, characterizing probiotics and starter cultures, and established the functional role of CRISPR-Cas as adaptive immune systems in bacteria. At NC State, he continues to study the molecular basis for their mechanism of action, as well as developing and applying CRISPR-based technologies for genotyping, building immunity and genome editing.
Producers: Sarah Goodwin, Rebecca Ellsworth
Cinematographer: Derek Reich
Editor: Rebecca Ellsworth\
Graphics: Chris George, Maggie Hubbard
Assistant Camera: Gray McClamrock
Drone aerials: Travis Jack
Supervising Editor: Regina Sobel
Field Producer: Meredith DeSalazar
Interview by: Adam Bolt
Associate Producer: Shelley Elizabeth Carter
Executive Producers: Shannon Behrman, Sarah Goodwin, Elliot Kirschner
Except where otherwise noted, this work is licensed under
creativecommons...
© 2007-2022 Science Communication Lab™. All rights reserved.
#biology #research
We have gathered all of our CRISPR films in a playlist. You can find the playlist here: ruclips.net/p/PLXwMdtHQav9Yob-hq8tsATQ-ANZJKB1Kc
ruclips.net/video/eA0AQlMy2CU/видео.htmlsi=cj1OD2FFPflnAe_H
Phenomenal storytelling. Great story! Love his excitement for biology and science.
Thank you so much! We can't wait to share more of the projects we are working on.
Fantastic video! This channel is an absolute goldmine for exceptional content, thank you! 🙏🏼
SOO TRUE I've been sharing almost every video to the corresponding friends and colleagues hahha
@@jf8070 🥰
The team that put this together should be congratulated! Epic content.
High-quality science. Congratulations to Dr Rodolphe and the SCL time for this amazing material.
Thanks so much for the compliment and for watching!
Well done! Great job we'll all be thankful for. Also excellent video quality.
Que bonita manera de narrar los experimentos. Se nota su emoción y su alegría.
Such an incredible and fascinating story!
Loved to know how it started!
they sent product and company using says it didnt work so they test and find the culture is dead (he says this) and seems the clip in this video same location as in this one ruclips.net/video/eA0AQlMy2CU/видео.htmlsi=cj1OD2FFPflnAe_H
Great video. Thanks. Keep them coming. 😊
gracias por tanto saludos from Bo
Super cool!
I hope you guys receive a Nobel prize like the other crispr scientists who got the gene editing ideas.
Same question here.
Doudna has left the chat
ahem. ruclips.net/video/eA0AQlMy2CU/видео.htmlsi=VH5l6p7jHZp8G5D8&t=1463
Amazing
I love the license plate!
Mojica
Transferring interoceptive diaphragmatic homeostasis monitoring while getting proper feedback from acid -base balance of blood buffer strength(Michael'-Mentens enzyme first-rate substrate constant.half velocity. 1922.
Why can't we add CAS sequences to Corona virus o that it does not infect human?
thats not how crispr works sir
Viruses keep mutating, better to change human body to react to viruses faster but that difficult due to possible off site changes and regulation
Adding crispr CAS 9 geneediting to rice plants and make them less toxic to heavy metals like lead, cadmium(super phosphate fertilizers), requires biological monitoring for these heavy metals interest in .Metallothionein protein should be able to adopt crispr CAS 9 gene editing in rice plants and more basic studies have to be made in field trial by the Regression analysis, since cadmium and lead accumulate in the bones. teeth and be placentally transferred to the foeataL blood causing diseases like it a i -it a i (0ouch -ouch painful joints) i and often osteomyelitis .The W H O guidelines for Crispr CAS9 short cuts should be non-toxic.
It is like production of antibodies against the human spermatozoa tail antigen and block conception, which is why corona virus is pandermic. There's no point in adding CAS sequence to corona virus, so gay to infect humans.
You can modify coronavirus so it doesn’t infect humans but the normal coronavirus that does infect humans is still around
👍🇧🇩
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Better Living Through .... Science!!!
Geez-o-peezies I _LOVE_ cheeses!!!
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Francis
The only fact I don’t like about this video is, that it is focused on animal milk.
ruclips.net/video/eA0AQlMy2CU/видео.htmlsi=cj1OD2FFPflnAe_H
Videos that spend too much time setting up the stage have obviously too little to tell us. I don't have patience waiting for it.
Well, i disagree
The video was perfectly passed and that was absolutely necessary to deliver that sudden stinger at the end. Must be a bit frustrating for the guy to not be recognized for the discovery of the fundamentals of CRISPR
Anyways, i often find that is not about the content, exclusively, but also about how your present it. And, in my honest opinion, this video managed to be informative, funny and engaging
Well done!
Imagine being so dopamine deprived, terminally online, and braindead that you can't appreciate the backstory that led to someone's incredibly impactful worth. If two minutes disturb you so much I bet you can't even brush your teeth. Gross.
Japan is trying to discharge radioactively contaminated water into the sea, and I'm curious about this part.
Francis Mojica christianized the sustem: CRISPR.
Salinas de Santa Pola.
Spain
ruclips.net/video/eA0AQlMy2CU/видео.htmlsi=AIItqW5Agjjaf7Pz&t=911