Thank you Dr. Neil. It was an easy way to learn one of the most difficult subjects! One point I would like to add is that in First Aid 2020, the timing for "Acute hemolytic transfusion reaction" is changed to "During transfusion or within 24 hours(due to preformed antibodies)". Also, "Delayed hemolytic transfusion reaction" is added which has the onset of over 24 hours within 1-2 weeks, with symptoms like mild fever and hyperbilirubinemia.
Trying to make videos more concise and under 15 minutes. We will try and be more efficient and save you time when studying. Hope this is helpful. Keep Moving Forward...!!
We need more videos Dr. Neil! We're lost without you! You don't know just how many questions you got me through on my exam! Life saver!! Please add more subjects, more videos soon!!
@RandyNeilMD Can you make a complete usmle review? And yes, I've been watching all of your videos for years! I absolutely love them! When i was taking my exam, I was like, "Are you a question writer??? It seems to me that they're pulling questions from your videos!! Also, do you have glycogen storage diseases videos?? At least 10 questions were directly from your videos!
@@RandyNeilMD i do apologize for my spelling mistake, I already have updated my comment. Thank you so much your videos always very helpful, plz keep it up
Ladies and Gents, boys and girls, I give you The Randy Neil, 11th Hour Samaritan Extraordinaire, the hero we do not deserve but undeniably the hero we most definitely need.
All your videos are the best videos out there specially with the questions which reinforces by 100! Very grateful for your videos I’ve seen that i retain more with questions right after the topic
Thank you for the comment... I'll have to look at the milestones...my initial thought is that its memorization and I am not sure there are any tricks...but I will look at it. Keep studying hard!!
Thank you Dr. Neil you are like a blessing for me these days. and luckily you are making videos on those topic which I always get wrong , but now my questions are getting better . thankyou again for your time and giving us free videos.
Thanks so much again Dr. Neil. You've been such immense help. Funny enough, I thought I was the only one in my study group that knew about you, until my colleagues began referring to your videos. Just a kind request Dr. Anyway you can do a video on Androgen Insensitivity Syndrome vs 5 alpha-reductase, and other DSDs. Will be much appreciated. Thanks.
Thanks Doc . I find your videos really helpful and precise. Please can you make videos on respiratory and cardiac graphs from first aid. Really appreciate your efforts.
You need to add some neurology pathway videos along with their lesions and some cardio stuff please! You're doing awesome with these uploads and just in time. I'm literally burning out, been over a year and I've just been putting my exam date off and procrastinating, having study spells and off days where I just fall out of routine, and your videos are helping me a LOT!
Hello, Thanks for the video. very educational and you have made the reaction process so simple to understand. Thanks heaps. I have one concern though, could you please clarify the answer for the question at 10:00 - 10:30min. I understand as, pt reacted AFTER receiving 2 PINTS of blood. this is where I am confuse. Because, 1). its After the second pint before the reaction, 2). to receive 2 pints would have fall in the 6 hours window. could that be right or I am missing it??? thanks in advance
Dr Neil .. ur videos are really awesome. I have a question, in class case u mentioned it as anaphylactic rxn. But in question it says .. after receiving 2 pints of blood .. that means it was not immediately?
Thank you Doc for crystal clear concept. I have a doubt regarding one of the practice questions in this video related to Febrile Non Hemolytic Reaction... If we transfuse packed RBC ..how can we get this presentation ? WBC are not even present in the transfusion .. so what will be the benefit of Leukoreduction?
😊 thank u so much.. can u make a video on Michael menten kinetics , lineweaver Burke plot , competitive non competitive inhibitors 0 order and 1st order elimination and their graphs.... it will be really helpful. It’s kind of confusing with graphs...
I do have some stuff on pharmacokinetics/Pharmacodynamics... Honestly, its mostly stuff I got from other people...but I guess most everything is. Let me work on that.
The last question said the reaction was immediately "after" receiving two pints of blood - not while receiving the blood - so how can this be an anaphylactic reaction? Finishing a two pint transfusion must have taken around 1hr right?
Hey Dr.Neil loved your video but a small doubt, in the last question where the patient has chills and shortness of breath immediately then why can’t it be acute hemolytic anemia? Because in acute hemolytic anemia the patient has chills,tachypnea - time: during transfusion or within 24hours according to FA2020. And anaphylactic means usually they have wheezing,urticaria right.. so please can u explain
Maybe my question wasn't written as good as it should have been... I'm not that much of an expert to question your source. Perhaps you could make a video explaining... I based most of my stuff on timing... If you make a video we can incorporate into a future video.
I"m confused about the one where it say the 28yr male involved in a MVA has symptoms immediately after receiving 2 points/pints...... he wouldn't have received 2 pints of blood but if he did it would take hours so if he had a reactions hours after the transfusion begins it would be febrile non haemolytic instead of anaphylaxis. Righhhhtt??
So I just saw this question in an NBMEabout a patient who develops flank pain, hypotension WHILE receiving a blood transfusion. Then they stated that her urine is wine-colored. So...because it was WHILE receiving the blood I thought it was anaphylactic reaction. Wrong :( ABO incompatibility.
No worries... we can make all our mistakes and 'learning moments' now ...before our exam. It's all a learning process... Thank you for sharing and feedback. Keep studying HARD!!
The 28 year old with history of CAD was in two severe mother vehicle accidents? Lol, must be accident prone. Anyways, thank you Dr. Neil, this was very helpful.
I followed that rule in NBME 24 and I got the question wrong 😅 The question said the patient had respiratory issues after 45 min I disregarded TRLI and chose hemolytic reaction (wrong ) What did I do incorrectly?
I do have material on that ... That should be easy. I will see what I have in terms of questions. That was mainly on my radar for STEP 3, but I will put something together.
Hey.randy can you make videos on bacteria and virus genetics like recombination reassotment complementation phenotypic mixing and bacterial transformation conjugation transduction(generalized and specialized) and transposition.these are all very difficult and 5 to 6 questions come from thesr topics.
"Okay Randy Neil, Randy Neil okay, I see your blood transfusion reactions and I raise you transplant rejections. Whatchu gonna do now, Randy Neil?" Lol, great way to teach an overwhelming topic, keeping it simple by timing it just right. Absolute Awesomeness!
"immediately afytrr erecieving 2 pints" your anser is wrong.think about 2 pints.base on the history 2 pints already consumed so it has tobe feb non hem
![Felix "Unfair" | [Stray Kids : SKZ-PLAYER]](http://i.ytimg.com/vi/Oswujxm2Ag0/mqdefault.jpg)
Thank you Dr. Neil. It was an easy way to learn one of the most difficult subjects! One point I would like to add is that in First Aid 2020, the timing for "Acute hemolytic transfusion reaction" is changed to "During transfusion or within 24 hours(due to preformed antibodies)". Also, "Delayed
hemolytic transfusion reaction" is added which has the onset of over 24 hours within 1-2 weeks, with symptoms like mild fever and hyperbilirubinemia.
Thank you for the update.. Let me see if I can PIN this to the top of the comments so everyone can see... Thank you for the feedback
Thank you for adding these information.
They added Acute Lung injury atop the delayed hemolytic rxn
Trying to make videos more concise and under 15 minutes. We will try and be more efficient and save you time when studying. Hope this is helpful. Keep Moving Forward...!!
Thank you so much!
Thanku 🙂
We need more videos Dr. Neil! We're lost without you! You don't know just how many questions you got me through on my exam! Life saver!! Please add more subjects, more videos soon!!
Thank you for the kind words... Always looking to do more... It's hard to know which topics I have completed...
@RandyNeilMD Can you make a complete usmle review? And yes, I've been watching all of your videos for years! I absolutely love them! When i was taking my exam, I was like, "Are you a question writer??? It seems to me that they're pulling questions from your videos!! Also, do you have glycogen storage diseases videos?? At least 10 questions were directly from your videos!
0 - A-naphylactic ➡️ ig-A ➡️wAsh
1 - acute hemolytic ➡️ aBo incompatible ➡️ user error
6 - FEBRILE hemolytic ➡️ Cytokines ➡️ leuckoreduction
A- B -C
great summary, but remember it's febrile NON-hemolytic
I've never felt so motivated to learn the tough topics before! Thank you Dr. Randy!!
Ivy, Perfect... Glad ti is helpful.
i was so worried about these questions and you made it so easy!!! thank you!
You are most welcome Kinza
Thank you...I like the way you use questions to teach...I tend to learn more by questions instead of boring long lectures or monotonous reading
Hina, Thank you for the feedback... I agree... I couldn't stand the "lectures" or "Death by Powerpoint"... Glad you like it.
You always explain everything so easily. Why my teachers didn't explain like you, you are marvelous. God bless you always.
Thank you as always. I'm glad videos are helpful.
@@RandyNeilMD i do apologize for my spelling mistake, I already have updated my comment. Thank you so much your videos always very helpful, plz keep it up
Ladies and Gents, boys and girls, I give you The Randy Neil, 11th Hour Samaritan Extraordinaire, the hero we do not deserve but undeniably the hero we most definitely need.
Ha... I may just keep making videos so I can get comments like this. Much appreciated!!
@@RandyNeilMD YOU're appreciated!
Your explanations are topnotch
God bless you abundantly
Gregory, Glad it was helpful. Keep studying HARD!!
Wow I am so glad I saw this video right before the exam. Had no idea about leukoreduction or washing. Also timeframe can get really iffy. Thank you!
CRUSH the exam!!
All your videos are the best videos out there specially with the questions which reinforces by 100! Very grateful for your videos I’ve seen that i retain more with questions right after the topic
Appreciate the comment Jacob
Dr. Neil Thank you for all that you do. Excellent work.
You are most welcome.
so glad you're making these videos?
Vanessa, I'm glad they are helpful. Thank you for the comment.
Thank you so much for your work
You are most welcome. Keep me posted on your progress...
Its just amazing the way u jot things down in the simplest way possible. Really inspired from what u r doing...
Sheikh, Thank you for the comment.
Make video on delayed hemolytic reactions specifically graft vs host reaction.
I'm working on it...
Thank you so much for your effort. Please make a video On Learning Developmental Milestones.
Thank you for the comment... I'll have to look at the milestones...my initial thought is that its memorization and I am not sure there are any tricks...but I will look at it. Keep studying hard!!
Thank you Dr. Neil you are like a blessing for me these days. and luckily you are making videos on those topic which I always get wrong , but now my questions are getting better . thankyou again for your time and giving us free videos.
Maryam, It's all about "getting better"...so, keep up the good work and STUDY HARD!!
incredible teaching. I wish all my professors were like you
Thank you Amber... Appreciate the nice comment.
Amazing, Thank u ! Can u do a video about transplant rejections
Lana, You are killing me... That was one topic I had difficulty with... I will need to dig deep for that material. Thank you for the comment.
Thank you sooo much DR.Ryan. You made this so easy to understand. I was struggling before but now i can say i am a PRO. you are an excellent teacher.
Carisa, Glad it was helpful.
Excellent
Thank you.
Thank you so much man. From Kenya🇰🇪
Chebii, You are most welcome.
Wow, you make it so simple to understand and remember. Thank you very much.
Happy, You are most welcome.
Thanks so much again Dr. Neil. You've been such immense help. Funny enough, I thought I was the only one in my study group that knew about you, until my colleagues began referring to your videos.
Just a kind request Dr. Anyway you can do a video on Androgen Insensitivity Syndrome vs 5 alpha-reductase, and other DSDs. Will be much appreciated. Thanks.
Small world. I will look into that topic. It is a good one... I just haven't categorized it yet in my plans.
@@RandyNeilMD No qualms. Thanks Dr.
You are fabulous at stuff u do man . I’ve been watching all the videos since the Biostats one . Just amazing . Thanks a lot , grateful!!
Home Home, Thank you for the comment. Glad it was helpful
Awesome. Even useful for step 3. Keep up the good work!
Semere, Thank you for taking time to comment.
Thanks Doc . I find your videos really helpful and precise. Please can you make videos on respiratory and cardiac graphs from first aid. Really appreciate your efforts.
Respiratory is an area I struggled, but I can see what I have for the cardiac stiff. Do you mean 1st, 2nd degree heart blocks?
It’s my first time to understand this in 20yrs as a Dr,I’m yo new fan.a question:how do you treat those reactions?South Africa 🙏,
being a Psychiatrist... I might be the last person you want to treat this one...
thank you. just thank you
You are most welcome.
@@RandyNeilMD used this graph of yours to get nearly 4 questions on my step exam yesterday morning. Thank you
A great work. It’s really helpful and save lots of my time! Just love the old school learning style.
Thank you Princess Z...as always
All your videos are amazing!!!Thank you!!!!
P B, Thank you for the comment and feedback.
Great video ! Thank u !
Most welcome.
Thank you Dr. Neil for all you do for us. Amazing work and appreciated!
You are welcome Martina
Great video Dr.McNeil 👌
Thank you Dr Neil, very useful lecture!!
Glad it was helpful
Thank you Hero.
Amer, Appreciate the comment...ha
amazing video, I like how everything is in black and white.
Thank you for the comment and feedback...
You need to add some neurology pathway videos along with their lesions and some cardio stuff please! You're doing awesome with these uploads and just in time. I'm literally burning out, been over a year and I've just been putting my exam date off and procrastinating, having study spells and off days where I just fall out of routine, and your videos are helping me a LOT!
VIVI, When you get tired and start to burn out...THAT is when you actual start to separate yourself from the pack. OUTWORK them all...!!
Great video to memorize these. Thanks.
Ann, Thank you for taking time to comment.
Big thanks and love for you brother 🙏
Appreciate the comment.
This was great! thank you doctor
You are most welcome.
Thank you so much Doctor....amazing video
Mohammad, You are most welcome.
It is amazing.Thank you!
Shakhnoza, Thank you for the feedback
Amazing video very helpful. Thank you Dr. Neil.
You are most welcome.
Good content with easy explanation 👏👏👍👍
Thank you
Dr Neil , I was wondering what would you say is a good NBME score in order to safely pass Step 1 ? Thank you
Hard to say what is "good"... I believe that NBME can give you a good estimate about your real score +/- 10...
@@RandyNeilMD Thank you Dr. Neil for your reply
Well explained
Dr. Botan, Thank you for commenting
Hello, Thanks for the video. very educational and you have made the reaction process so simple to understand. Thanks heaps.
I have one concern though, could you please clarify the answer for the question at 10:00 - 10:30min. I understand as, pt reacted AFTER receiving 2 PINTS of blood. this is where I am confuse. Because, 1). its After the second pint before the reaction, 2). to receive 2 pints would have fall in the 6 hours window. could that be right or I am missing it??? thanks in advance
Dr Neil .. ur videos are really awesome. I have a question, in class case u mentioned it as anaphylactic rxn. But in question it says .. after receiving 2 pints of blood .. that means it was not immediately?
Thank you so much
Hossam, You're welcome.
Are there more lectures on blood n onco
I need to make some...
Great Job!
Thanks you very much sir ,
My Step 1 is after tomorrow .
Keep Going ,
Stay focused, Stay Confident... merely a step in the process. Keep moving forward...
Thank you for such an important topic and an easy way to it's explanations.
Btw Doc, are you planning to teach something about murmurs anytime soon?
KML, Thank you for the comment. let me see what I can dig up on murmurs...
@@RandyNeilMD thanks in advance doctor. 😁
This was great thank you!
You are most welcome.
Thank you sir for the great video.
Can the 2nd question in which patient has SOB after 45 min of transfusion be TRALI?
Samir, I wish I were that smart...
Thank you Doc for crystal clear concept. I have a doubt regarding one of the practice questions in this video related to Febrile Non Hemolytic Reaction... If we transfuse packed RBC ..how can we get this presentation ? WBC are not even present in the transfusion .. so what will be the benefit of Leukoreduction?
😊 thank u so much.. can u make a video on Michael menten kinetics , lineweaver Burke plot , competitive non competitive inhibitors 0 order and 1st order elimination and their graphs.... it will be really helpful. It’s kind of confusing with graphs...
I do have some stuff on pharmacokinetics/Pharmacodynamics... Honestly, its mostly stuff I got from other people...but I guess most everything is. Let me work on that.
Really good
i owe you my life
Wow. Thanks Randy✨✨✨
Si Lilly, You are welcome.
The last question said the reaction was immediately "after" receiving two pints of blood - not while receiving the blood - so how can this be an anaphylactic reaction? Finishing a two pint transfusion must have taken around 1hr right?
Appreciate it 🤝
You are welcome.
Hey Dr.Neil loved your video but a small doubt, in the last question where the patient has chills and shortness of breath immediately then why can’t it be acute hemolytic anemia? Because in acute hemolytic anemia the patient has chills,tachypnea - time: during transfusion or within 24hours according to FA2020. And anaphylactic means usually they have wheezing,urticaria right.. so please can u explain
Maybe my question wasn't written as good as it should have been... I'm not that much of an expert to question your source. Perhaps you could make a video explaining... I based most of my stuff on timing... If you make a video we can incorporate into a future video.
Awesome🎉
Thank you
I"m confused about the one where it say the 28yr male involved in a MVA has symptoms immediately after receiving 2 points/pints...... he wouldn't have received 2 pints of blood but if he did it would take hours so if he had a reactions hours after the transfusion begins it would be febrile non haemolytic instead of anaphylaxis. Righhhhtt??
Yes.
is the second one right? coz he doesnt have any hemolytic symptoms...isnt it febrile non hemolytic ?
if the patient recieved 2 pints of blood , it takes at least to run 2 pint about 3 hours ? is that anaphylaxic or acute ?
So I just saw this question in an NBMEabout a patient who develops flank pain, hypotension WHILE receiving a blood transfusion. Then they stated that her urine is wine-colored.
So...because it was WHILE receiving the blood I thought it was anaphylactic reaction. Wrong :( ABO incompatibility.
No worries... we can make all our mistakes and 'learning moments' now ...before our exam. It's all a learning process... Thank you for sharing and feedback. Keep studying HARD!!
@Yosira maybe this helps: ruclips.net/video/RWVzAJU_Mf4/видео.html
Thank you alot.. Need more videos like this ❤️❤️🙏
Orfa, Thank you for the feedback. Glad it was helpful!
But we often see NHFTR in the first hour!!
The 28 year old with history of CAD was in two severe mother vehicle accidents? Lol, must be accident prone. Anyways, thank you Dr. Neil, this was very helpful.
You are most welcome.
thank you so much :)
Riya, You are most welcome.
Tq doctor this vid...could u PLZ make a similar vid on Transplant rejection....(pg.119 fa2019)
I have that topic in the queue... I need to gather my materials for that one...
I followed that rule in NBME 24 and I got the question wrong 😅
The question said the patient had respiratory issues after 45 min
I disregarded TRLI and chose hemolytic reaction (wrong )
What did I do incorrectly?
Awesome
AWESOME... i saw this video and thought how easy is it to learn this. however got confused after First Aid's information.
Jigs, I felt the same way... I'm glad video was helpful. Thank you for commenting.
Sir...Can you pls explain fetal heart tracing and related question???
I do have material on that ... That should be easy. I will see what I have in terms of questions. That was mainly on my radar for STEP 3, but I will put something together.
@@RandyNeilMD I'm awaiting.... thanks
Kindly sir recommend a book for blood banking..
No clue on that one...
Hey.randy can you make videos on bacteria and virus genetics like recombination reassotment complementation phenotypic mixing and bacterial transformation conjugation transduction(generalized and specialized) and transposition.these are all very difficult and 5 to 6 questions come from thesr topics.
"Okay Randy Neil, Randy Neil okay, I see your blood transfusion reactions and I raise you transplant rejections. Whatchu gonna do now, Randy Neil?"
Lol, great way to teach an overwhelming topic, keeping it simple by timing it just right. Absolute Awesomeness!
Thank you for the comment... I would have to go back a look at the transplant stuff... Gonna make me work on this...
@@RandyNeilMD Lol, all in good time Doc, you know we ain't goin nowhere! Much appreciated, as always.
The last que looks like TRALI
Repeating one thing time and again.
Yes, repetition is key...
"immediately afytrr erecieving 2 pints"
your anser is wrong.think about 2 pints.base on the history 2 pints already consumed so it has tobe feb non hem
I was confused about this tbh. It takes time to give two pint so it could not be anaphylactic. Can anyone clear this plz?