What parents need to know about Duchenne muscular dystrophy
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- Опубликовано: 10 фев 2018
- This video explores the most common muscular dystrophy in children called Duchenne muscular dystrophy (DMD), a genetic disorder. DMD is explained through signs and symptoms, pathogenesis, diagnosis and disease progression. Studies were used to explain the benefits of exercise as well as treatment with Deflazacort.
This video was made by Demystifying Medicine students Lamisha Khandaker, Kunal Mehta, Michelle Rong, and Dhruvika Joshi.
Copyright McMaster University 2018
If you'd like to learn more about DMD and how you can help, please visit:
www.mda.org/disease/duchenne-...
Here are the 2 studies mentioned in the video:
Study on Delflazacort:
Griggs, R. C., Miller, J. P., Greenberg, C. R., Fehlings, D. L., Pestronk, A., Mendell, J. R., . . . Meyer, J. M. (2016, November 15). Efficacy and safety of deflazacort vs prednisone and placebo for Duchenne muscular dystrophy. Retrieved January 18, 2018, from n.neurology.org/content/87/20/...
Study on Exercise:
Jansen, M., Alfen, N. V., Geurts, A. C., & Groot, I. J. (2013, July 24). Assisted Bicycle Training Delays Functional Deterioration in Boys With Duchenne Muscular Dystrophy: The Randomized Controlled Trial "No Use Is Disuse". Retrieved January 18, 2018, from www.researchgate.net/publicat...
References:
Le Guiner, C., Servais, L., Montus, M., Larcher, T., Fraysse, B., Moullec, S., ... & Koo, T. (2017, July 25). Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy. Retrieved January 18, 2018, from www.nature.com/articles/ncomm...
McDonald, C. M., Henricson, E. K., Abresch, R. T., Florence, J., Eagle, M., Gappmaier, E., . . . Peltz, S. W. (2013, July 17). The 6‐minute walk test and other clinical endpoints in duchenne muscular dystrophy: Reliability, concurrent validity, and minimal clinically important differences from a multicenter study. Retrieved January 18, 2018, from onlinelibrary.wiley.com/doi/10...
Ropars, J., Lempereur, M., Vuillerot, C., Tiffreau, V., Peudenier, S., Cuisset, J., . . . Brochard, S. (2016, September 13). Muscle Activation during Gait in Children with Duchenne Muscular Dystrophy. Retrieved January 18, 2018, from journals.plos.org/plosone/arti...
Ruiten, H. J., Straub, V., Bushby, K., & Guglieri, M. (2014, September 3). Improving recognition of Duchenne muscular dystrophy: a retrospective case note review. Retrieved January 18, 2018, from adc.bmj.com/content/early/2014...
Sienkiewicz, D., Kulak, W., Okurowska-Zawada, B., Paszko-Patej, G., & Kawnik, K. (2015, July). Duchenne muscular dystrophy: current cell therapies. Retrieved January 18, 2018, from www.ncbi.nlm.nih.gov/pmc/arti...
Sussman, M. (2002). Duchenne Muscular Dystrophy. Journal of the American Academy of Orthopaedic Surgeons, 10(2), 138-151.
Vohra, R. S., Lott, D., Mathur, S., Senesac, C., Deol, J., Germain, S., . . . Vandenborne, K. (2015, June 23). Magnetic Resonance Assessment of Hypertrophic and Pseudo-Hypertrophic Changes in Lower Leg Muscles of Boys with Duchenne Muscular Dystrophy and Their Relationship to Functional Measurements. Retrieved January 18, 2018, from journals.plos.org/plosone/arti... 
Хобби
I have this problem I am age 13 I now sit in the weelchair but I am doing exercise
Great explanation! but, PLEASE, that scratching sound when the doctor takes notes....
That was awesome!
My uncle had muscular dystrophy and he died in 2003 at my great grandmothers house
@ my brother also has DMD
Does anyone else have DMD now?
@@laleshahqeldiyeva9343my step son has it. My bio son and I just found out and we're trying to come to terms with it.
How will you diagnose if the patient has normal crp report but have all other symptoms of DMD ?
Plz guide me about.muscular dystrophy
that doctor is cross-eyed the whole time
My friend at school has this
Im a Moroccan guy aged 25 years old and suffering from Becker Muscular Dystrophy .I really would like to know if there is any cure available at your hospital to treat my desease or at least stop its progress and makes my mobility improves abit and are there any clinical trials going on volunteering patients in which i can participate and thank you in advance
Take IGF 1 inj. Upto 3 dose after take tell me what is the results if you interest to buy i will suggest the dealer contact
@@pkmishra9206 what's igf?
@@IT-tm8plbefore stem cell therapy
Are you walking? When were you diagnosed? Please answer my question
my son have this situation at age of 8 he cant able to walk
So sad, I am sorry to hear about
I am doing steroids I can still walk I am 10
I will never forget the day I came across dr igho channel on RUclips , I will always keep it memorable, thank you doctor for helping me cure my muscle dystrophy & pain completely , and putting a smile on my face , you made me feel more alive like never before, Thank you Dr Igho
ဘာကိုလဲ
Please help me DMD patient is my son
My son affected by DMD ducenne muscular dystrophy exons deleted 3-30
9 years old boy please help me any treatment to cure
Assalamo alikum
Ap ks city Sai hain
My son affected by DMD
What about girls, it’s unlikely but it happens?
This genetic disease, which causes progressive loss of muscle function, is in fact seen far more often in boys than in girls - but girls and women aren't completely excluded from getting it. Most women who carry a genetic mutation that can cause Duchenne won't develop the condition
Take IGF 1 inj. Upto 3 dose after take tell me what is the results if you interest to buy i will suggest the dealer contact
My brother have a also that problem i want to try inj.
@@parmarjaydipsinh774 Good👍👍
I can try, please tell me
ဘာဆေးလဲ
DMD medicine have
Where the DMD medicine available
PK Mishra
Mostly in the western world
iam suffering from muscular dystrophy
Me too bro
Is there any treatments for muscular dystrophy?? Pls suggest me
Me too I get bullied a lot and they say I look like a duck
Take steroids medicine like IGF 1 inj.
Take IGF 1 inj. 3 dose And tell me after what you get the results
#driyaremoses channel
I want to die man my life is so ruined.
Your life is not ruined
Don't worry, God bless you
If you do power meditation daily two set then within a month you will get relief in pain and improvement in body movement for further information please contact me on whatsapp 91 9322303271 so I can send you video of power meditation
@@kantilalbhanushali7572 You are from INDIA
@@dinshtube3819 yes just now I am at Mumbai Ghatkopar