What is chirality and how did it get in my molecules? - Michael Evans
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- Опубликовано: 2 авг 2024
- Improve your understanding of molecular properties with this lesson on the fascinating property of chirality. Your hands are the secret to understanding the strange similarity between two molecules that look almost exactly alike, but are not perfect mirror images.
Lesson by Michael Evans, animation by Safwat Saleem and Qa'ed Tung.
Oh my god, this is my organic chemistry teacher at UIUC! I can't wait to tell him I saw this video.
tell him i want ted back
Yo, so how did the convo go that day..?
@@oliverdayton3827 Damn. It took me 15 minutes too. But it didn't work!!
@@samuraijosh1595 lmao i wanna know too
RNA World experiments involve a long series of Highly orchestrated steps which include purifying desired products, removing unwanted byproducts, changing physical and chemical conditions, adding unrealistically high concentrations of assisting substances and other interventions to ensure that the target molecules are achieved. It's highly manipulated controlled chemistry that has no relevance to the Early Earth!
Proto-cells are not life-like, the requisite ribosomes mRNA, enzymes and reagents were purchased from a chemical company or extracted from a pre-existing living system. Then added to the medium and permitted to diffuse into the manmade plastic capsules.
The center for chemical evolution is not making progress!
The experimental setups are permeated with clever manipulations tweaking pH and temperature as needed along the way using UV radiation at the right times and durations to remove problematic side-products, highly purified chemicals, it bears no relevance to pre-biotic conditions!
chirality it one of these things that make organic chemistry so hard for me, thanks for the video, it helps a lot especially right before my test!
RNA World experiments involve a long series of Highly orchestrated steps which include purifying desired products, removing unwanted byproducts, changing physical and chemical conditions, adding unrealistically high concentrations of assisting substances and other interventions to ensure that the target molecules are achieved. It's highly manipulated controlled chemistry that has no relevance to the Early Earth!
Proto-cells are not life-like, the requisite ribosomes mRNA, enzymes and reagents were purchased from a chemical company or extracted from a pre-existing living system. Then added to the medium and permitted to diffuse into the manmade plastic capsules.
The center for chemical evolution is not making progress!
The experimental setups are permeated with clever manipulations tweaking pH and temperature as needed along the way using UV radiation at the right times and durations to remove problematic side-products, highly purified chemicals, it bears no relevance to pre-biotic conditions!
I read once that there's some work of fiction where a man's chirality gets flipped, and at first it's just amusing because his dominant hand switched, but then it turns out he can't digest food because his body molecules have the wrong chirality to interact with the food molecules correctly…
do you remember what it's called?
NoriMori Technical Error by Arthur C Clarke?
I would advise this man to try some OTC nasal spray ;-)
@@metacylinder That's definitely the story
It's not a big plot point or anything but in "To be taught, if fortunate" they're astronaut exploring a few planets and they eventually notice different planets have organisms that digest different chirality molecules, even one planet where organisms can digest both .
good video! Although I found disturbing al the "funny comment bubbles"... they didn't let me concentrate on what was really important, what you were trying to teach.
The animation for this lesson is just brilliant!
outstanding animation and nice presentation............thank you
Wow. Excellent. Spatial Geometry combined with History and Chemistry. So seldom do I see such synthesis!
Strange coincidence: I learned about chirality today for the first time while watching episode 2 (or 3) of Breaking Bad, and then this video pops up... always amuses me when I see or learn about something for the first time in my life, only to have cross my path again seemingly by pure chance on the same day. I don't believe in any significance to coincidences, but one can't shake the eerie feeling when such things happen few times in a row.
Arthur78 same happened with me.
Where did you watch it and did you have Alexa or Google listening to you watch it?
This is called the Baader Meinhof Phenomenon
It's called yt algorithm.... Ur data goes to all these sites
Top Notch Tutorial on Chirality! Thank You So Much for Sharing! ♥️🌷🕯
such a video I have seen it can not explain in word ..... thank you so much keep it up
That awesome moment when you see this video in your feed and you just learned about chirality a few hours ago in organic chem class.
your phone hears all and sees all
I dont understand why at 1:35 you got asymmetric molecules, but at 3:10 you got symmetric molecules? Is there a mistake?
in that one its a mirror image
At 3:10, they are not "symmetric". Outside the mirror, Br is sticking out of the screen (represented by solid triangle pointing to C) and Cl is sticking into the screen (represented by dashed triangle). The mirror one would be the opposite, with Br going in, Cl coming out.
It is a mistake. You're right Mr. Random that Br should be sticking out of the screen, but in the 3D model they made, it's not. You can see this at 3:12 when the white dotted line passes barely in front of the "r" in "Br".
Even if they had gotten that right, they should have also swapped the dashed/solid triangles in the mirror image.
this video explained something that i was incredibly confused about in a perfect manner. thank you so much
Just studied this in chem! Love it :3
Beautifully explained
Interesting. I always though the bonded atoms around the carbon can freely rotate but they merely vibrate. Now I finally understand the chirality...
Thank you so much, I was so confused about what a left handed amino acid was
what a video !!!!!!!!! i want to learn every subject in this manner only//////
Walter White brought me here
Wrong example used at 1:35 . The molecules aren't mirror images of one another, they are stereoisomers, but aren't enantiomers (as hands are), they are diastereomers (as hands aren't).
Thanks for the clarification/correction, Daniel. Looks like I have 3 new words to learn!
yes you can see the F and H swap positions, is this why you define them the way you do?
4 years ago
still out there
they are mirror images of one antother. br(bromine) is out of the plane and if we place a mirror b/w them, br will remain out of the plane but f and h will chnage positions... plz reply if this analogy is wrong.
There are two main form of stereoisomerism: cis-trans and enantiomers. Mirror image can display enantiomerism when they are non-superimposable (meaning that when the mirror image are placed on top of one another, they cannot give the same molecule). I thought that diastereomers are any stereoisomers tat is not enantiomers. Correct me if i am wrong... we are all here to learn :)
They are mirror image. Not sure if Ted edited the footage.
Thanks a lot :)
fractals also explain our consciousness, you can apply the term fractal or resonance, ive been leaning toward resonance these days, seems to fit and concresce a little better(explains the same thing as fractal). I loved learning all about the patterns. It led me to Terence Mckenna and Alan Watts. who are easily some of the smartest minds to ever grace this planet. Alan watts talks a lot about neurological resonance, he was an utter genius.
A RUclips video just explained chirality better than my science teacher.
It is certainly interesting, this issue of chirality.
I felt like I got this and understood it completely, so afterwards I began re-watching this for no apparent reason until I remembered that I was really fucking baked.
Loved it
A five minute one at that. Most science teachers take about 3 lessons/lectures to teach the concept.
Thank you
If you bond a chiral object to its mirror image along the axis of reflection, isn't the resulting object achiral?
awww i wanted it to explain more about it
more o chem!...i love it
Is this gonna be on the murder?
TheArchsage74 What. Yes I mean no maybe doesn’t hurt to know it right knowledge is power
congratulations! :D
It doesn't seem that you are tired with these Debates, Considering that is the entire content of your channel :o
Symmetry and chirality are not the same, I think it means that since people like symmetry, we don't make objects that are (for example) bigger from one side than the other and then make the same object inverted so they look like mirrored images.
Of course symmetric objects will look the same on the mirror, but chiral objects NEED the mirror to look the same, that's the thing.
If there's a great concept then it should be able to be explained simply.
If you're interested in natural shapes and patterns of the universe, learn about fractals and how they can explain the structure of plants, lightning, entire planets, circulatory systems, and more
I don't understand optical rotation. And what are other chiral objects besides hands and screws?
I love ted ed
Well, not being able to translate and rotate an object on its mirror image is the definition of chirality, yes. My point is that it does not make sense to say that people don't like chirality because they like symmetry since you can make everything axially symmetric if you mirror it. And people use this to a great extent as the fleurons I borrowed from Unicode show.
But doesn't chirality depend on perpective? If you hold a pencil such that you hands are parallel and the tip points to your left palm, then the object is chiral. But if point the pencil prependicular to your eyes, then it isn't chiral...(to give an example)
How chiral compounds interact?
What Wiki says:
"The origin of this homochirality in biology is the subject of much debate. Most scientists believe that Earth life's "choice" of chirality was purely random, and that if carbon-based life forms exist elsewhere in the universe, their chemistry could theoretically have opposite chirality. Circularly polarised radiation could have caused the selective destruction of one chirality of amino acids, leading to a selection bias which resulted in all life on Earth being homochiral."
I think you're asking the wrong question. Chiral molecules are simply two different ways of forming a molecule. It's usually based on the position of the atoms when they bond together. At no point did some event happen to "create" chirality.
Where did everyone go D:
How did all of this come about after the big bang? Did it "evolve"?
Any porters here?
👍
What?
@@MarioMario-jt7ld what?
Personal experience: I'm right-handed and sometimes buy jackets with left-handed zippers. It's really frustrating to zip them up with the "wrong" hand.
I was talking about HOW THIS CHIRALITY OCCURRED.
you are very smart :D
At 1:48 the molecules are not mirror images of each other
When you stick out your hands like that the palms are flipped the other way xD
How do the cicadas make so much noise?
BUT, if I can put my palms together, everything lines up, its a mirror, and since its all lined up perfectly, why isnt it superimposable? D:
Remember your hands aren't 2D. Place your left hand palm down. If you line the fingers of your right hand up with your left your right hand will be palm up - not the same. They are mirror images but not superimposable.
Walter White explained this like a boss!
can u just give the topic detail completely by explaining Evey thing every point related to a particular point
ちょうど光学異性体の乳酸について勉強していたのでこの動画をみつけられて良かった
K I know u r here for learning some chemistry but I can't be the only one who remembers skins because of the intro right?
Hideo Kojima games always teach me new words.
1)He did not say it has been pointed out yet.
2) He says it because there is a possibility something like that could be brought up LATER.
"Major" and "minor" in music is chiral, too.
You sure?
i learned this from breaking bad ! :)
Non orient able spaces can turn left
then the pencil isn't chiral at all, he went over that with the molecule when he said it didn't matter how he orientated the molecule, it wouldn't have all the parts in the same place from the same viewpoint. he could get a mirror image, but that isn't identical.
Chirality deals with objects in three dimensions, not just two.
Mais alguém fazendo prova do sesi?
Yet, at a fundamental level this reflection-symmetry is broken. The Weak Force (one of the 4 fundamental forces) explicitly breaks this symmetry (know as parity).
Amen! ;)
3:16
Mit University 💖💖 I'm in
What Einstein has to do with chirality?
Ok, and now I only need to know why it appears to be that there are only left-handed neutrino's...
Yeah but that's chirality in organic molecules, not chirality in general. You didn't specify and i figured you meant in general because you said "after the big bang". Like i said your asking the wrong question. What I'm guessing you want to know is why life on earth only uses one out of the two. Which you answered yourself.
Only thing I would add is that the random choice would be supported by evolution because its easier to form macro molecules if all of the parts are the same.
The evidence that homochirality could occur through natural processes in life/for the creation of life is something we can calculate using mathematical probabilities. The probability that natural processes could produce this feature is 0%.
the clock at the star is at 9 11 o.o
Firstly, an account of billions of years of cosmic happenings is not an idea, it is a history. Secondly, powerful ideas and theories often escape simple explanation ( see v=wMFPe-DwULM ). If you really want to know the answer rather then make empty objections you could read a "Bang!: The Complete History of the Universe" or a similar work, or try the wikipedia page on the "chronology of the universe".
nuh uh, magical sky d00d
ladies and gentlemen, this is how you start a comment war.
I Know you are here yong.
YONG OUT!!!
YONG YEA!
I bet hideo kojima watched this video for at least 20 times.
this tough me nothing im sorry. it basically summed up that molecules are just mirrored
Learned this from Breaking Bad!
those two molecules are not mirror images of each other
Guy looks like Handsome Jack
Written language is chiral.
except MAYBE for, loosely, palindromes :)
I'm so confused...
Hi
BUT YOU ANC ROTATE YOUR HAND AND THEN THEY ARE SUPERIMPOSABLE
If you rotate then the back of your hand and palm face you. I think achiral would be if the hand had palms on both sides.
And creating a cell from randomness (evolution) is impossible when chirality of the molecules is involved
Intelligence is always required to generate genetic information!
The RNA world has failed!
Coping?
@@carmen_13 amino acids come in left and right-handed but life only uses the left-handed variety, and they have to be sequenced in a specific correct order in order to have a functional protein.. purely natural chemical processes have never achieved this.
And RNA World experiments involve a long series of Highly orchestrated steps which include purifying desired products, removing unwanted byproducts, changing physical and chemical conditions, adding unrealistically high concentrations of assisting substances and other interventions to ensure that the target molecules are achieved. It's highly manipulated controlled chemistry that has no relevance to the Early Earth!
Proto-cells are not life-like, the requisite ribosomes mRNA, enzymes and reagents were purchased from a chemical company or extracted from a pre-existing living system. Then added to the medium and permitted to diffuse into the manmade capsules.
The center for chemical evolution is not making progress!
The experimental setups are permeated with clever manipulations tweaking pH and temperature as needed along the way using UV radiation at the right times and durations to remove problematic side-products, highly purified chemicals, it bears no relevance to pre-biotic conditions!
Who else read "chirality" as "charity"...?
I hate it when people say that God didn't create man, do I look like a freaking mokey??? So stupid!
God did create man! :)
G
This is complex
That animation was actually rather distracting with all of the dialogue boxes, I ended up reading those and not really paying attention. *sigh*
I thought thumb was a finger
People like symmetry, so there aren't many chiral objects? ❧❧❧ Didn't make sense to me! ☙☙☙
Didn't explain How it got there!!!
Breaking bad anyone?
L