How to calculate protein-protein interactions in PyMol?

Поделиться
HTML-код
  • Опубликовано: 26 окт 2024

Комментарии • 9

  • @naimatasnim9796
    @naimatasnim9796 12 дней назад

    Excellent video! My question is, if I have two different sequences of proteins, how can I show the interaction between them?

    • @Bioinformaticsinsights
      @Bioinformaticsinsights  11 дней назад +1

      You need to first dock them. In case you want to follow my tutorial, here is the link.
      ruclips.net/video/-5s_EuS4cak/видео.html
      Once a docked complex is ready, you can use this Interaction video again.

    • @naimatasnim9796
      @naimatasnim9796 11 дней назад

      @@Bioinformaticsinsights thank you so much

  • @zeeshankhan-mo3sd
    @zeeshankhan-mo3sd 7 месяцев назад

    You have done great job

    • @Bioinformaticsinsights
      @Bioinformaticsinsights  7 месяцев назад

      Thanks for taking interest. Please share it in your community, it might help some one else too.

  • @MunibKhan-l6t
    @MunibKhan-l6t Месяц назад

    hello sir, please can you guide how to measure the distance between two residues and how to label them in a protein-protein docked complex, there are a lot of videos related to the ligand and protein interaction, but its difficult to apply those in case of protein-protein docked complex

  • @juliangrandvallet5359
    @juliangrandvallet5359 4 месяца назад

    This is extremely helpful, Dr. Quick question, what happens if I already know the interaction sited between the 2 proteins? Can I give that to the script? Because I want to compare the interaction between 2 different proteins (2 different PDB codes)

    • @Bioinformaticsinsights
      @Bioinformaticsinsights  4 месяца назад

      @Julia if you the interaction interface exactly, then I suggest you to show those residues in PyMol. Why you want to tell the script the these two residues, the script is supposed to identify those two already. In case not then look to he script and tweak the cutoff distance, save and rerun. Yes you can identify between two different proteins, if they are in a complex. If they are individual proteins from PDB, in that case you have to dock them first.