PhD in Microbiology here. "OAT" has no clinical usefulness for anything it claims. For example, it says it can detect water soluble vitamin deficiencies (among others). The problem is that the kidneys have tubular recovery mechanisms of folate, vitamin B12, (and their carrier proteins). It's a pointless test that will change every hour. Besides, urine and serum plasma concentrations of B12, folate, etc are different than tissue bound. Next up, Candida. Urine tests for Candida metabolites have zero established efficiency. Even a paper by Jones et al (2019) says this: "There is no good evidence that urine tartaric acid analysis or organic acid profiling is useful in the diagnosis of fungal infection." It is worth noting the tests recommended by the European Society of Clinical Microbiology and Infectious Diseases for the diagnosis of Candida infections: culture, serum mannan/anti-mannan antibodies, serum B-D-Glucan, direct microscopy and histopathology. The "Organic Acid Test" from Great Plains laboratory is a LDT test, with no human studies to support it's use. Not a single one. It's sad that this test assigns arbitrary RRs for metabolites with no source to support what is a proper level, and not only that, it will change hour to hour. Jones SL, Campbell B, Hart T. Laboratory tests commonly used in complementary and alternative medicine: a review of the evidence. Annals of Clinical Biochemistry. 2019;56(3):310-325. doi:10.1177/0004563218824622
Thank you for your insight, Gary! I pinned your comment so that more people see it and read it. In truth, this has been my strong hunch all along. I've been meaning to do a deep dive into the validity of OAT testing, but hadn't gotten to the task yet. After I discovered how WILDLY inconsistent the GI Map is, I figured I'd start with the consistency question first. Then, hopefully soon, I can move onto validity and clinical utility.
@@gutmicrobiomequeen GI MAP is another LDT test. It has the same flaws as the Great Plains "OAT" test. Microbiome is an emerging science. Davenport et al (2017) state the following about the microbiome: "The relative proportions of each of these taxa vary dramatically [7] between individuals [8] and even within an individual over the course of their lives [9,10,11]." What that means is that your microbiome is nearly unique, to you. Sure, there may be some taxa that cause x/y/z, but that has not been established, and there's no Reference Ranges of what certain ones should be, ie: Bacteroidetes, Firmicutes, Actinobacteria, and Proteobacteria ratios. Davenport, E.R., Sanders, J.G., Song, S.J. et al. The human microbiome in evolution. BMC Biol 15, 127 (2017). doi.org/10.1186/s12915-017-0454-
Agreed. I have seen this with my experiments (I've done probably 20-30 stool tests on myself this past year for various projects for this channel). Fwiw, though, having seen many stool tests on patients over the years- it is possible to change/manipulate your microbiota to a certain degree. Similarly, after seeing enough cases, you do get a sense of pattern recognition and pre- and post-intervention symptomatic changes with stool testing. So, it's not worthless... it's just 1. not well documented and 2. evolving every day. That's why we all need to be observant and mentally flexible. I hate to see people (professionals and lay people alike) place 100% of their trust in ONE test, ONE company, ONE guru/expert, or ONE way of thinking (ex. "carbs are bad!" "no, meat is bad!" "NO, plants are bad!"). Nothing in life is that simple, predictable, or static... life itself makes damn sure that life stays exciting 🤣
@@gutmicrobiomequeen the microbiome changes hour to hour, day to day. How much are those changes and what the changes are? unknown. There's some papers that indicate the microbiome is influenced by circadian rhythms
I don't know if it changes drastically in that span of time. Like I said, I've done 20-30 stool tests on myself this year, and my microbiome is remarkably stable from sample to sample. Of note, the tests I've been using represent everything as a % of the total microbiota rather than absolute values. I will also say that I tend to focus only down to the genus level, typically. If you're using a test that tries to give you an absolute measurement (like the GI Map or OAT) or if you're looking at super specific markers (like a single species or metabolite), I bet you'll get more variation. Also, yes! The microbial clock thing is fascinating! I talk about that a bit in FODMAP Freedom. The big take away being that the microbiota get their circadian ques from us and our behavior, so we'd better try to give them good, consistent information (so, consistent sleep and mean timing).
Yes, yes, yes! Would love a video on the OATs markers and/or fungal markers. Find the OATs tests fascinating! Thanks for doing all of these experiments 🙏
Okay, I will officially add that to my "to record" list :) It won't be soon bc I have a ton of videos lined up for winter and spring, but I'll make it happen!
Hi, great video and it confirmes my trust in this test! For Candida it’s the best test to do, a friend of mine did a stool, a blood and another urine test elsewhere, all were NEGATIVE for arabinose while the OAT test of GPL showed a 500% excess which finally confirmed the clinical diagnosis of a severe Candida overgrowth!
I haven't made up my mind if I believe in this test's ability to diagnose yeast overgrowth, honestly. That pattern you shared (all other tests are negative and this one was ragingly positive) means one of two things: 1. That this test is that much better than all the others OR 2. This test is overdiagnosing yeast overgrowth. I could honestly go either way. I'm going to need to do a research deep-dive to try to verify the markers on this test before I can comment further.
@@gutmicrobiomequeen I would rather add to this that Candida overgrowth, just like chronic Lyme, would rather be a clinical diagnosis! Dr Marty Ross has a very well thought questionnaire which alarmed my friend with a very high score to consider doing the OAT test, a different approach to measure the overgrowth “anywhere” in his body by measuring the metabolites it produces. Maybe those metabolites don’t stay long in the blood (reason why it wasn’t detected in his blood), as the body prefers to filter them out as “toxins” as fast as possible! This friend of mine has many allergies, food intolerances and malabsorption, which make me suspect the Candida overgrowth is probably located in his small intestine, which in turn is difficult to detect through a stool analysis (as this only reflects life in the colon). Are you still with me why I think the OAT test is probably the most accurate, but a clinical diagnosis would still be needed to create a personalized treatment plan. I’m not a clinician, but a mold/Candida survivor having spent a ton of my time understanding the complex nature of this overgrowth and why so many clinicians miss it, leaving their clients in their suffering.
Will do Naveed! I just have to research them first to figure out how validated they are. No sense in teaching you how to interpret a test if it's not going to tell you anything useful!
Hey Nicole, thanks for another great and informative video. I’ve ordered an OAT test all the way from Europe and I should be getting the result finally after 5 weeks of waiting, so the timing couldn’t be any better. These series investigating consistency really helps keep companies honest. And I’d be very interested in a video on how to interpret the OAT test, personally. Thanks and happy new year!!!
I'm putting it on my to do list for 2023 to do a deep dive on these markers and how validated and accurate they are. Regarding the fungal markers in particular, I think one of two things is true: 1. That this test is that much better than all the others OR 2. This test is overdiagnosing yeast overgrowth. I could honestly go either way.
Great work. Are you reporting this to the lab(s)? They definitely should know. Maybe they would then strive to review their compliance and testing standards. I’m not as forgiving as you are on these issues. These are professional labs. There are no excuses! If it’s not almost exactly the same, it’s bad on their part!! Are their personnel not adequately trained?
The majority of these markers (with 1-2 exceptions) were close enough that I'm not too worried about it. However, in my opinion, the inconsistencies/problems with the GI Map stool test were absolutely unforgivable.
This is a great video and I am looking forward to more, particularly the one you mention regarding the validity (or not) of organic acids' implications. I am a traditional provider who recently has discovered them world of functional lab testing. In my view there is some value to be found in this realm. And... the opposite. Beyond that there is a lack of a critical eye being cast on these tests from within the functional world. So again your contributions here are most welcome. I am wondering if you ever use any of the tests available in the realm of the trendy topic of "methylation." I would love to see a comparison of those (Genova's Panel vs Doctor's Data Panel). I'll share my Organic Acids anecdote. I've had Genova's "ION" panel done twice. Some of the Organic Acids data directly contradicted results that came from the "DUTCH" testing, an approach more concerned with hormonal metabolites. Genova's data in some cases seemed spot on because when I did use it's data to make interventions there were positive improvements. .
I used this test several times. It depicted, intestinal, candida, and Cdiff along with some other markers, being high. I was incredibly sick when I took these tests. Including white tongue and much more. After being treated, I took the tests again. Cdiff cleared after conventional antibiotics, and candida was down dramatically, using holistic approach. I further treated the candida holistically, took another OATS test, and it was gone. I felt dramatically better until the PI - IBS kicked in That said, it was a four year battle with two episodes of Cdiff and constant candida which has now triggered PI - IBS. I'm back in intestinal hell for who knows how long brutal. Essentially I worked so hard for four years to get rid of my infections only to get PI - IBS.😫 I feel this though the OATS test was very accurate in my case.
My favorite macronutrient tests are Vibrant’s and Spectracell’s micronutrient test. I will not depend on any test that doesn’t measure nutrients at the tissue or cellular level. Would be nice for you to do test from both on the same day and compare the results.
I'm putting it on my to do list for 2023 to do a deep dive on these markers and how validated and accurate they are. I think one of two things is true: 1. That this test is that much better than all the others OR 2. This test is overdiagnosing yeast overgrowth. I could honestly go either way.
Would be great to have a video on arabinose and its reliance for candida. Specially as arabinose is present in many foods. Also please comment on neurotransmitters.
I'm putting it on my to do list for 2023 to do a deep dive on these markers and how validated and accurate they are. Particularly the yeast markers. I think one of two things is true: 1. That this test is that much better than all the others OR 2. This test is overdiagnosing yeast overgrowth. I could honestly go either way.
Do you ever do the ION, I see practitioners over diagnosis and supplement with those labs. The amino acids, neurotransmitters, carb/fat metabolism etc. I think it’s used poorly, would love your thoughts.
Good question! I've never used the ION. I spoke to Genova a while back and they said it's roughly equivalent to the NutrEval. The biggest difference is that you can order ION in NY state, but you cannot get the NutrEval there. Since I was already familiar with the NutrEval, I've never bothered switching. I agree though- functional practitioners and the like tend to over-prescribe supplements. In particular, with tests like these. You can see my results in these videos- I'm not without abnormal readings here and there! But I'm not running out to supplement every single one of them. In my opinion, this work is all about the big picture and how the patient is feeling. If the big picture looks decent and they feel good, I'm personally not going to over-think it. I'm not sure if that makes me a really good provider or a really bad one 😂 Guess it depends on the individual person's philosophy on health. To the person who just wants to live a reasonably healthy life and feel good, I'm their gal. For people who feel the need to optimize and "biohack" every little detail of their physiology, I am definitly NOT their person. Because I don't think that works nearly as well as people think it does 😂
I am late to the party but am sad to see the comment you pined regarding the OAT having no clinical usefulness?? I have herd other Functional Docs speak highly of this test but I do understand what was said in the comment pined below. I certainly was excited for an Indepth video on interrupting the OAT. but it seems you agree that its clinically insignificant??? and your next video is on comparing 2 Oats so what gives??? please help me understand. is there is value in certain aspects of the OAT?? your thoughts would be greatly appreciated!
That comment was made by a phd in microbiology (not biochem). You get a lot of arrogant insecure people under age 30/40 proud to flex their degree. Usually those with decades of clinical experience are more humble. Such as the Functional Doctors that support this test, some with 50 years experience. When they say the microbiome/values change hour to hour that's a red flag of a young degree flexer. Same arguably applies to every blood/urine test. Point is there are averages and everyone has kidneys lol. May as well say everyone has HPHPA and their HVA/VMA ratio changes from extremely high to normal every hour. I've had 4 stool tests with undetected Akkermansia, it's unlikely it reappears 2 hours later after everyone in my family consistently has it on their tests from the same company. Most people have it appear on every test, compared to it being undetected 4 times straight...
Which test do you consider most valid Organix acid test serum tests microbiome tests? what do you think about hair mineral analysis? have you heard about myBiome from synlab ?
I don’t really understand what your conclusion is here…? I was thinking you’re leaning towards saying “it’s not that accurate” but other commenters seem to be thinking you’re saying it’s a valid and reliable test ?
I don't recommend the GI Map at all. There are too many WILD inconsistencies with that test. I posted a video about it here on RUclips, but I was forced to remove it, so sadly you can't watch it anymore. An upper endoscopy would be my #1 choice, possibly followed by a SIBO breath test as Victor suggested. Then again, SIBO breath tests are notoriously awful (high rates of false positives and false negatives), too. Siiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiigh.
PhD in Microbiology here.
"OAT" has no clinical usefulness for anything it claims. For example, it says it can detect water soluble vitamin deficiencies (among others). The problem is that the kidneys have tubular recovery mechanisms of folate, vitamin B12, (and their carrier proteins). It's a pointless test that will change every hour. Besides, urine and serum plasma concentrations of B12, folate, etc are different than tissue bound.
Next up, Candida. Urine tests for Candida metabolites have zero established efficiency. Even a paper by Jones et al (2019) says this:
"There is no good evidence that urine tartaric acid analysis or organic acid profiling is useful in the diagnosis of fungal infection."
It is worth noting the tests recommended by the European Society of Clinical Microbiology and Infectious Diseases for the diagnosis of Candida infections: culture, serum mannan/anti-mannan antibodies, serum B-D-Glucan, direct microscopy and histopathology.
The "Organic Acid Test" from Great Plains laboratory is a LDT test, with no human studies to support it's use. Not a single one. It's sad that this test assigns arbitrary RRs for metabolites with no source to support what is a proper level, and not only that, it will change hour to hour.
Jones SL, Campbell B, Hart T. Laboratory tests commonly used in complementary and alternative medicine: a review of the evidence. Annals of Clinical Biochemistry. 2019;56(3):310-325. doi:10.1177/0004563218824622
Thank you for your insight, Gary! I pinned your comment so that more people see it and read it.
In truth, this has been my strong hunch all along. I've been meaning to do a deep dive into the validity of OAT testing, but hadn't gotten to the task yet. After I discovered how WILDLY inconsistent the GI Map is, I figured I'd start with the consistency question first. Then, hopefully soon, I can move onto validity and clinical utility.
@@gutmicrobiomequeen GI MAP is another LDT test. It has the same flaws as the Great Plains "OAT" test. Microbiome is an emerging science.
Davenport et al (2017) state the following about the microbiome:
"The relative proportions of each of these taxa vary dramatically [7] between individuals [8] and even within an individual over the course of their lives [9,10,11]."
What that means is that your microbiome is nearly unique, to you. Sure, there may be some taxa that cause x/y/z, but that has not been established, and there's no Reference Ranges of what certain ones should be, ie: Bacteroidetes, Firmicutes, Actinobacteria, and Proteobacteria ratios.
Davenport, E.R., Sanders, J.G., Song, S.J. et al. The human microbiome in evolution. BMC Biol 15, 127 (2017). doi.org/10.1186/s12915-017-0454-
Agreed. I have seen this with my experiments (I've done probably 20-30 stool tests on myself this past year for various projects for this channel).
Fwiw, though, having seen many stool tests on patients over the years- it is possible to change/manipulate your microbiota to a certain degree. Similarly, after seeing enough cases, you do get a sense of pattern recognition and pre- and post-intervention symptomatic changes with stool testing. So, it's not worthless... it's just 1. not well documented and 2. evolving every day. That's why we all need to be observant and mentally flexible. I hate to see people (professionals and lay people alike) place 100% of their trust in ONE test, ONE company, ONE guru/expert, or ONE way of thinking (ex. "carbs are bad!" "no, meat is bad!" "NO, plants are bad!"). Nothing in life is that simple, predictable, or static... life itself makes damn sure that life stays exciting 🤣
@@gutmicrobiomequeen the microbiome changes hour to hour, day to day. How much are those changes and what the changes are? unknown.
There's some papers that indicate the microbiome is influenced by circadian rhythms
I don't know if it changes drastically in that span of time. Like I said, I've done 20-30 stool tests on myself this year, and my microbiome is remarkably stable from sample to sample. Of note, the tests I've been using represent everything as a % of the total microbiota rather than absolute values. I will also say that I tend to focus only down to the genus level, typically. If you're using a test that tries to give you an absolute measurement (like the GI Map or OAT) or if you're looking at super specific markers (like a single species or metabolite), I bet you'll get more variation.
Also, yes! The microbial clock thing is fascinating! I talk about that a bit in FODMAP Freedom. The big take away being that the microbiota get their circadian ques from us and our behavior, so we'd better try to give them good, consistent information (so, consistent sleep and mean timing).
Yes, yes, yes! Would love a video on the OATs markers and/or fungal markers. Find the OATs tests fascinating! Thanks for doing all of these experiments 🙏
Okay, I will officially add that to my "to record" list :) It won't be soon bc I have a ton of videos lined up for winter and spring, but I'll make it happen!
Hi, great video and it confirmes my trust in this test! For Candida it’s the best test to do, a friend of mine did a stool, a blood and another urine test elsewhere, all were NEGATIVE for arabinose while the OAT test of GPL showed a 500% excess which finally confirmed the clinical diagnosis of a severe Candida overgrowth!
I haven't made up my mind if I believe in this test's ability to diagnose yeast overgrowth, honestly. That pattern you shared (all other tests are negative and this one was ragingly positive) means one of two things: 1. That this test is that much better than all the others OR 2. This test is overdiagnosing yeast overgrowth. I could honestly go either way. I'm going to need to do a research deep-dive to try to verify the markers on this test before I can comment further.
@@gutmicrobiomequeen I would rather add to this that Candida overgrowth, just like chronic Lyme, would rather be a clinical diagnosis!
Dr Marty Ross has a very well thought questionnaire which alarmed my friend with a very high score to consider doing the OAT test, a different approach to measure the overgrowth “anywhere” in his body by measuring the metabolites it produces. Maybe those metabolites don’t stay long in the blood (reason why it wasn’t detected in his blood), as the body prefers to filter them out as “toxins” as fast as possible!
This friend of mine has many allergies, food intolerances and malabsorption, which make me suspect the Candida overgrowth is probably located in his small intestine, which in turn is difficult to detect through a stool analysis (as this only reflects life in the colon). Are you still with me why I think the OAT test is probably the most accurate, but a clinical diagnosis would still be needed to create a personalized treatment plan. I’m not a clinician, but a mold/Candida survivor having spent a ton of my time understanding the complex nature of this overgrowth and why so many clinicians miss it, leaving their clients in their suffering.
Good you're doing this work, doesn't seem anyone else has ever bothered testing these labs.
For REAL, weiss27md! For. Real. Somebody's gotta do it.
Hi Nikki, happy new year. Yes, please can you go through each marker in the OATS test.
Will do Naveed! I just have to research them first to figure out how validated they are. No sense in teaching you how to interpret a test if it's not going to tell you anything useful!
Hey Nicole, thanks for another great and informative video. I’ve ordered an OAT test all the way from Europe and I should be getting the result finally after 5 weeks of waiting, so the timing couldn’t be any better.
These series investigating consistency really helps keep companies honest.
And I’d be very interested in a video on how to interpret the OAT test, personally.
Thanks and happy new year!!!
Thanks, Victor! Happy new year to you, too!
Thanks for doing this scientifically. I'm very interested in the next video about the NutraEval!
This week's video (posting 1/12/23) will be a great one :)
A vid on how to interpret the organic acids tests would be truly awesome!
I'm putting it on my to do list for 2023 to do a deep dive on these markers and how validated and accurate they are. Regarding the fungal markers in particular, I think one of two things is true: 1. That this test is that much better than all the others OR 2. This test is overdiagnosing yeast overgrowth. I could honestly go either way.
very interesting video.. I use organic test for testing on patients, so this was very interesting to see that they are fairly consistent..
Great work. Are you reporting this to the lab(s)? They definitely should know. Maybe they would then strive to review their compliance and testing standards. I’m not as forgiving as you are on these issues. These are professional labs. There are no excuses! If it’s not almost exactly the same, it’s bad on their part!! Are their personnel not adequately trained?
The relative difference between both tests is actually surprisingly small. And you shouldn’t forget standard measuring errors.
The majority of these markers (with 1-2 exceptions) were close enough that I'm not too worried about it. However, in my opinion, the inconsistencies/problems with the GI Map stool test were absolutely unforgivable.
This is a great video and I am looking forward to more, particularly the one you mention regarding the validity (or not) of organic acids' implications.
I am a traditional provider who recently has discovered them world of functional lab testing. In my view there is some value to be found in this realm. And... the opposite.
Beyond that there is a lack of a critical eye being cast on these tests from within the functional world. So again your contributions here are most welcome.
I am wondering if you ever use any of the tests available in the realm of the trendy topic of "methylation." I would love to see a comparison of those (Genova's Panel vs Doctor's Data Panel).
I'll share my Organic Acids anecdote. I've had Genova's "ION" panel done twice. Some of the Organic Acids data directly contradicted results that came from the "DUTCH" testing, an approach more concerned with hormonal metabolites. Genova's data in some cases seemed spot on because when I did use it's data to make interventions there were positive improvements.
.
Yes, please make a video on how to interpret the test! It would be much appreciated
I used this test several times. It depicted, intestinal, candida, and Cdiff along with some other markers, being high. I was incredibly sick when I took these tests. Including white tongue and much more. After being treated, I took the tests again. Cdiff cleared after conventional antibiotics, and candida was down dramatically, using holistic approach. I further treated the candida holistically, took another OATS test, and it was gone. I felt dramatically better until the PI - IBS kicked in That said, it was a four year battle with two episodes of Cdiff and constant candida which has now triggered PI - IBS. I'm back in intestinal hell for who knows how long brutal. Essentially I worked so hard for four years to get rid of my infections only to get PI - IBS.😫 I feel this though the OATS test was very accurate in my case.
My favorite macronutrient tests are Vibrant’s and Spectracell’s micronutrient test. I will not depend on any test that doesn’t measure nutrients at the tissue or cellular level. Would be nice for you to do test from both on the same day and compare the results.
Love this. You’re the best
😘😘😘
I'd be interested on more details on each of the markers, also would be interesting to see the difference between the Genova one and this one.
I'm putting it on my to do list for 2023 to do a deep dive on these markers and how validated and accurate they are. I think one of two things is true: 1. That this test is that much better than all the others OR 2. This test is overdiagnosing yeast overgrowth. I could honestly go either way.
17:37 yes please, do a video on it
Yes!
Lots of "yes" answers to that question! I love it! Now to do a super-nerd deep dive to see how validated these markers are!
Please, please do more videos about OAT! :)
Ok! Right after I research the markers to see how validated they are :) No sense in teaching you how to interpret a test if it's based on rubbish!
Would be great to have a video on arabinose and its reliance for candida. Specially as arabinose is present in many foods.
Also please comment on neurotransmitters.
I'm putting it on my to do list for 2023 to do a deep dive on these markers and how validated and accurate they are. Particularly the yeast markers. I think one of two things is true: 1. That this test is that much better than all the others OR 2. This test is overdiagnosing yeast overgrowth. I could honestly go either way.
id love a full breakdown of how this differs from info that a stool test can give, comparing advantages and disadvantages
It's definitely an "apples and oranges" comparison, but I can take a stab at it :)
Thank you for this video!!!!!!!!!!!!!
gratitude for this video
🥰
Thanks for the nerdy info 🤓
You're welcome :)
Do you ever do the ION, I see practitioners over diagnosis and supplement with those labs. The amino acids, neurotransmitters, carb/fat metabolism etc. I think it’s used poorly, would love your thoughts.
Good question! I've never used the ION. I spoke to Genova a while back and they said it's roughly equivalent to the NutrEval. The biggest difference is that you can order ION in NY state, but you cannot get the NutrEval there. Since I was already familiar with the NutrEval, I've never bothered switching.
I agree though- functional practitioners and the like tend to over-prescribe supplements. In particular, with tests like these. You can see my results in these videos- I'm not without abnormal readings here and there! But I'm not running out to supplement every single one of them. In my opinion, this work is all about the big picture and how the patient is feeling. If the big picture looks decent and they feel good, I'm personally not going to over-think it. I'm not sure if that makes me a really good provider or a really bad one 😂 Guess it depends on the individual person's philosophy on health. To the person who just wants to live a reasonably healthy life and feel good, I'm their gal. For people who feel the need to optimize and "biohack" every little detail of their physiology, I am definitly NOT their person. Because I don't think that works nearly as well as people think it does 😂
I am late to the party but am sad to see the comment you pined regarding the OAT having no clinical usefulness?? I have herd other Functional Docs speak highly of this test but I do understand what was said in the comment pined below. I certainly was excited for an Indepth video on interrupting the OAT. but it seems you agree that its clinically insignificant??? and your next video is on comparing 2 Oats so what gives??? please help me understand. is there is value in certain aspects of the OAT?? your thoughts would be greatly appreciated!
That comment was made by a phd in microbiology (not biochem). You get a lot of arrogant insecure people under age 30/40 proud to flex their degree. Usually those with decades of clinical experience are more humble. Such as the Functional Doctors that support this test, some with 50 years experience. When they say the microbiome/values change hour to hour that's a red flag of a young degree flexer. Same arguably applies to every blood/urine test. Point is there are averages and everyone has kidneys lol. May as well say everyone has HPHPA and their HVA/VMA ratio changes from extremely high to normal every hour. I've had 4 stool tests with undetected Akkermansia, it's unlikely it reappears 2 hours later after everyone in my family consistently has it on their tests from the same company. Most people have it appear on every test, compared to it being undetected 4 times straight...
Have you considered doing a micronutrient test from the following labs: Spectracell, Vibrant America, and Cell Science Systems?
Which test do you consider most valid Organix acid test serum tests microbiome tests?
what do you think about hair mineral analysis?
have you heard about myBiome from synlab ?
You were forced to remove the one GI Map video?
I don’t really understand what your conclusion is here…? I was thinking you’re leaning towards saying “it’s not that accurate” but other commenters seem to be thinking you’re saying it’s a valid and reliable test ?
For reflux is it better to get the GI Map or OAT?
I’d get a SIBO breath test if I were you (if you live in the US, Trio Smart test is best). Especially if you bloat after eating certain foods.
I don't recommend the GI Map at all. There are too many WILD inconsistencies with that test. I posted a video about it here on RUclips, but I was forced to remove it, so sadly you can't watch it anymore. An upper endoscopy would be my #1 choice, possibly followed by a SIBO breath test as Victor suggested. Then again, SIBO breath tests are notoriously awful (high rates of false positives and false negatives), too. Siiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiigh.
Thanks! 🙏🙏🙏